scholarly journals Chronic kidney disease pada kucing domestic short hair

2021 ◽  
Vol 5 (2) ◽  
pp. 23-24
Author(s):  
Andrea Puput Handayani ◽  
Vici Eko Handayani ◽  
Tiara Widyaputri

Chronic kidney disease (CKD) merupakan kelainan struktural dan fungsional ginjal yang bersifat irreversibel, sehingga ginjal mengalami penurunan hingga kehilangan fungsinya. Kasus ini ditulis untuk melaporkan proses penentuan diagnosa dan penanganan CKD pada kucing di klinik hewan Citrapet and Vet, Cibubur, Bekasi. Seekor kucing luar ruangan berkelamin betina dibawa ke klinik hewan dengan keluhan kondisi lemas dan tidak mau makan selama 3 hari. Temuan klinis menunjukkan turgor kulit > 2 detik, diare, banyak pinjal, saluran cerna kosong dan banyak gas, serta ginjal teraba berukuran besar. Pemeriksaan hematologi dan kimia darah terjadi penurunan kadar hemoglobin, penurunan hematokrit, leukositosis, limfositosis, granulositosis dan azotemia. Pemeriksaan urinalisis diperoleh nilai BJ dibawah normal, hematuria, proteinuria dan leukosituria. Pencitraan ultrasonografi menunjukkan batas antara pelvis renal, korteks dan medula tidak jelas pada kedua ginjal dan pola anekhoik yang diduga cairan tampak pada ginjal kanan. Kucing didiagnosa CKD dengan prognosa infausta. Terapi yang diberikan adalah pemberian antibiotik, antidiare, probiotik dan suplemen ginjal. Pemilik memutuskan rawat jalan setelah perawatan selama 10 hari dengan kondisi letargi, nafsu makan buruk dan sudah tidak menggalami diare.

Author(s):  
Jiwoon Kim ◽  
Ji Sun Nam ◽  
Heejung Kim ◽  
Hye Sun Lee ◽  
Jung Eun Lee

Abstract. Background/Aims: Trials on the effects of cholecalciferol supplementation in type 2 diabetes with chronic kidney disease patients were underexplored. Therefore, the aim of this study was to investigate the effects of two different doses of vitamin D supplementation on serum 25-hydroxyvitamin D [25(OH)D] concentrations and metabolic parameters in vitamin D-deficient Korean diabetes patients with chronic kidney disease. Methods: 92 patients completed this study: the placebo group (A, n = 33), the oral cholecalciferol 1,000 IU/day group (B, n = 34), or the single 200,000 IU injection group (C, n = 25, equivalent to 2,000 IU/day). 52% of the patients had less than 60 mL/min/1.73m2 of glomerular filtration rates. Laboratory test and pulse wave velocity were performed before and after supplementation. Results: After 12 weeks, serum 25(OH)D concentrations of the patients who received vitamin D supplementation were significantly increased (A, -2.4 ± 1.2 ng/mL vs. B, 10.7 ± 1.2 ng/mL vs. C, 14.6 ± 1.7 ng/mL; p < 0.001). In addition, the lipid profiles in the vitamin D injection group (C) showed a significant decrease in triglyceride and a rise in HDL cholesterol. However, the other parameters showed no differences. Conclusions: Our data indicated that two different doses and routes of vitamin D administration significantly and safely increased serum 25(OH)D concentrations in vitamin D-deficient diabetes patients with comorbid chronic kidney disease. In the group that received the higher vitamin D dose, the lipid profiles showed significant improvement, but there were no beneficial effects on other metabolic parameters.


VASA ◽  
2012 ◽  
Vol 41 (3) ◽  
pp. 159-160
Author(s):  
Espinola-Klein ◽  
F. Dopheide ◽  
Gori

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