The present survey for the ethno-botanical study was conduct on Khairabad Valley, Dir lower PK Pakistan, which as contain a lot of wild medicinal. Collect information including local names, local medicinal uses, Status of plants. A total of 50plants were collected, out of which 4 were gymnosperm and 46belong to angiosperm. Belong to 32family, out of this the familyLiliaceae was leading contain 8specie, followed by family Solanaceae with 3 specie, and family Apiaceaetwo specie, Rosaceae and Rutaceae consist threespecie and the remainingall consist of single species on the basis of the their statusthe plant were divided in to herb 50%, shrub 18%, tree 30% and climber 2%. 6plant uses were as tonic, four were as anticancer, three purgative and two plants were used as antiseptic, 6 are laxative, 4for wound, 3 used for digestive disorder, 5 sedative, 9use as a pain killer, 2 for blood stopping, 4 used as anthelimintis, 4 carminative, 2 used for vomiting, 5 for lever disorder, 5 headache, 7 for cough, 4 as a purgative, 3 ar0matic, 2 hemorrhoids, 4 astringent, 4 used as anti inflammatory.