scholarly journals PATTERN OF PROSTATIC DISEASE

2010 ◽  
Vol 17 (04) ◽  
pp. 573-577
Author(s):  
SADIA HAMEED ◽  
AKRAM MALIK ◽  
SAIRA BILAL ◽  
SHAHID RIAZ DOGAR ◽  
SHAZIA ASLAM
Keyword(s):  
Case Series ◽  
Intraepithelial Neoplasia ◽  
Prostatic Disease ◽  
Case Series Study ◽  
The Mean ◽  
Study Case ◽  
Well Differentiated ◽  
Series Study ◽  
Study Setting ◽  
Period Duration

Objectives: Analysis of the pattern of prostatic disease in Faisalabad. Design of Study: Case series study. Setting: Department of Pathology, University Medical and Dental College (UM&DC) and Meezan Laboratory (ML). Period: Duration of the study is three years. Methods and Materials: All prostatic specimens presenting to the Pathology department at the UM&DC and ML for histopathology were included. Results: During this period 540 prostatic biopsies were examined. The mean age of the patients was 67 years. Out of these 467(86.5%) were benign, 2 (0.3%) had prostatic intraepithelial neoplasia and 71 (13.5%) were malignant. All the cases of malignancies were adenocarcinomas. Most of them were well differentiated (Gleason’s score 2-4). The highest incidence of hyperplasia and malignancy occurred between 60-70 years of age. Conclusions: The incidence of prostatic cancer is on the rise and measures should be taken for early detection.

scholarly journals Triple Procedure for Dense Cataractous Neovascular Glaucoma Patients

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Hossam M. Moharram ◽  
Shaaban Abd-Elhamid Mehany Elwan ◽  
Mahmoud M. Nassar ◽  
Mohamed F. Abdelkader
Keyword(s):  
Case Series ◽  
Neovascular Glaucoma ◽  
Panretinal Photocoagulation ◽  
Case Series Study ◽  
Triple Procedure ◽  
Distant Visual Acuity ◽  
Pars Plana ◽  
The Mean ◽  
Series Study

Purpose. One of the most difficult refractory glaucomas is the neovascular type (NVG), and its association with dense cataract adds to this difficulty. This study aimed to provide results of the triple surgical procedure for such conditions. Methods. 12 eyes of 12 patients with NVG and dense cataract were included in this case series study. The mean age of patients was 57.25 ± 5.9 years. The mean preoperative intraocular pressure (IOP) was 47.25 ± 4.04 mmHg with maximum antiglaucoma therapy. The mean best corrected distant visual acuity (BCDVA) in LogMAR was 2.13 ± 0.38. All patients received intravitreal injection of 1.25 mg (0.05 ml) bevacizumab followed by phacoemulsification, pars plana vitrectomy (PPV) including panretinal photocoagulation (PRP), and trabeculectomy with mitomycin C (MMC). Mean IOP and BCDVA changes were the main outcome results of this study. Results. The follow-up period was 2 years. The mean BCDVA was improved to 1.22 ± 0.35, 1.13 ± 0.34, 1.12 ± 0.37, 1.06 ± 0.38, and 1.01 ± 0.37 at 1, 3, 6, 12, and 24 months, respectively, after this procedure. This improvement was statistically significant when compared with preoperative BCDVA (P<0.0001). The mean postoperative IOP was dropped to 20.08 ± 4.1, 17.08 ± 2.1, 17.17 ± 5, 15.75 ± 4.7, and 16.17 ± 6.1 mmHg, respectively. At the last follow-up, the mean IOP was statistically significantly lower than preoperative IOP (P<0.0001) at the previously mentioned time points. The success rate was complete in 90.9% of eyes and qualified in 100% of eyes. Iris and angle neovascularization had regressed significantly in all patients, and no serious complications occurred during the follow-up period. Conclusions. This triple surgery can safely improve patients with NVG and dense cataract regarding BCDVA and IOP control. This trial is registered with NCT04143620.

scholarly journals Clinical profile of SUNCT/SUNA in Japan: A clinic-based study

2019 ◽  
Vol 2 ◽  
pp. 251581631982990 ◽  
Author(s):  
Shoji Kikui ◽  
Junichi Miyahara ◽  
Hanako Sugiyama ◽  
Kentaro Yamakawa ◽  
Yoshihiro Kashiwaya ◽  
...  
Keyword(s):  
Case Series ◽  
Japanese Patients ◽  
Preventive Therapy ◽  
Short Term ◽  
Case Series Study ◽  
Clinical Profiles ◽  
The Mean ◽  
Series Study ◽  
Headache Center

Objectives: This study aimed to report the clinical profiles of patients with short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT)/short-lasting unilateral neuralgiform headache attacks with cranial autonomic (SUNA) in a Japanese population by surveying those enrolled at a regional headache center in Japan. Methods: In this consecutive case series study, the clinical characteristics of patients with SUNCT (eight men, three women; mean age: 59.5 ± 20.5 years) and SUNA (five men, four women; mean age: 51.3 ± 18.4 years) who visited Tominaga Hospital from February 2011 to January 2017 were examined. Headaches were diagnosed according to the International Classification of Headache Disorders, Third edition (ICHD-3) guidelines. Results: Brief clusters of separate attacks were reported by all patients. The mean duration of attacks was 91.9 ± 87.9 s. Ipsilateral rhinorrhea was observed in 9 of 20 (45.0%) cases and facial sweating was observed in 1 of 20 (5.0%) cases. An eminent response to lamotrigine was observed in 9 of 9 (100%) patients; however, adverse events were only reported in 2 of 9 (22.2%) cases. An intravenous infusion of lidocaine was demonstrated to be completely successful for short-term prevention in 5 of 6 (83.3%) SUNCT cases. Conclusions: Lamotrigine can successfully treat most patients, and intravenous lidocaine is useful for the short-term preventive therapy of severe recalcitrant attacks in Japanese patients with SUNCT/SUNA.

Functional and Radiographic Outcomes of Minimally Invasive Intramedullary Nail Device (MIIND) for Moderate to Severe Hallux Valgus

2020 ◽  
pp. 107110072096967
Author(s):  
Carlo Biz ◽  
Alberto Crimì ◽  
Ilaria Fantoni ◽  
Jacopo Tagliapietra ◽  
Pietro Ruggieri
Keyword(s):  
Hallux Valgus ◽  
Case Series ◽  
Radiographic Outcomes ◽  
Case Series Study ◽  
Significant Correction ◽  
The Mean ◽  
Series Study ◽  
Severe Hallux Valgus

Background: This study was aimed at assessing clinical and radiographic outcomes of the Minimally Invasive Intramedullary Nail Device (MIIND) to correct moderate to severe hallux valgus (HV) and the long-term persistence of its effects. Methods: This case series study involved 100 patients, 84 women and 16 men (mean age, 59 years), who underwent the MIIND procedure with a mean follow-up of 97 months. Assessment was performed preoperatively, postoperatively, at 6 and 12 months, and at last follow-up. Clinical outcomes were evaluated with American Orthopaedic Foot & Ankle Society (AOFAS) scores, visual analog scale (VAS), and patient satisfaction. Intermetatarsal angle (IMA), metatarsophalangeal hallux valgus angle (HVA), distal metatarsal articular angle (DMAA), and tibial sesamoid position were assessed. Statistical analysis was performed. Results: The mean AOFAS score improved from 57.9 to 90.5 points, VAS scale was 1.5 ± 2.0, and patients’ satisfaction was 8.7 ± 1.4. The mean correction of the HVA and IMA showed a significant correction; however, the effect of time was not statistically significant on DMAA. Sex ( P = .047), severity ( P = .050), associated procedures ( P = .000), and preoperative angle ( P = .000) showed significant association with HVA correction and its persistence over time. Age was not statistically significant. Complications were 9 cases of superficial wound infection and 6 recurrences. Conclusions: The MIIND technique proved a viable procedure to correct moderate to severe HV with a low rate of complications and recurrence, producing significant correction of most radiographic parameters assessed and their persistence, even at long term. Level of Evidence: Level IV, case series study.

Partial capitate shortening for Kienböck’s disease

2014 ◽  
Vol 40 (9) ◽  
pp. 957-960 ◽  
Author(s):  
A. Citlak ◽  
U. Akgun ◽  
T. Bulut ◽  
M. Tahta ◽  
B. Dirim Mete ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Case Series ◽  
Magnetic Resonance Images ◽  
Stage Ii ◽  
Pinch Strength ◽  
Case Series Study ◽  
The Mean ◽  
Series Study ◽  
Carpal Height

The purpose of this study was to report our experience of partial capitate shortening in seven patients with a median 38 months follow-up. Staging was made by the Lichtman classification system and stage II and III-A patients were included in the study. The mean age was 34 years (range 22–52). Patients were assessed for pain, range of motion, grip and pinch strength, and satisfaction was recorded using a scale between 0 and 4. All these parameters showed improvement after surgery. The Lichtman stage, lunate height index and carpal height index were determined radiographically. Magnetic resonance images of the wrist were studied for lunate revascularization at the final follow-up and occurred in all patients. According to our study, partial capitate shortening seems an effective treatment for Lichtman stage II and III-A patients. Level IV case series study.

scholarly journals Subconjunctival injections of triamcinolone acetonide to treat uveitic macular edema

2019 ◽  
Author(s):  
Yi Qu ◽  
Xinshu Liu ◽  
Anyi Liang ◽  
Chan Zhao ◽  
Fei Gao ◽  
...  
Keyword(s):  
Macular Edema ◽  
Triamcinolone Acetonide ◽  
Case Series ◽  
Subconjunctival Injection ◽  
Retrospective Case ◽  
Case Series Study ◽  
Uveitic Macular Edema ◽  
The Mean ◽  
Series Study

Abstract Background: To evaluate the efficacy and safety of subconjunctival triamcinolone acetonide (TA) injections for treating uveitic macular edema (UME). Methods: This retrospective case series study included patients with UME who received subconjunctival TA injections with a minimum follow-up period of 6 months. The main outcome was central macular thickness. The secondary outcomes included the best corrected visual acuity, recurrence rate and intraocular pressure. Results: In total, 68 patients (83 eyes) were enrolled in this study. The mean CMT decreased from 456.9 ± 171.1 μm at baseline to 324 ± 175.9 μm, 305.6 μm ± 147.7 μm, 331.8 ± 154.3 μm and 281.1 ± 147.6 μm at 1, 2, 3 and 6 months postinjection, respectively (all P < 0.01). A total of 21/83 eyes exhibited elevated IOPs, which was controlled with topical IOP-lowering agents in 14 eyes, whereas 7 eyes got subconjunctival TA deposit surgically removed. Conclusion: subconjunctival TA injections appear to be safe and effective for UME.Key Words: Triamcinolone acetonide; subconjunctival injection; uveitis; macular edema

scholarly journals SUBFERTILE PATIENTS

2016 ◽  
Vol 23 (02) ◽  
pp. 152-155
Author(s):  
Shazia Abbass ◽  
Ejaz Ahmed ◽  
Iram Shabbir
Keyword(s):  
Pregnancy Rate ◽  
Case Series ◽  
Primary Treatment ◽  
Monthly Income ◽  
First Line ◽  
Case Series Study ◽  
Rate Study ◽  
Series Study ◽  
Study Setting ◽  
Line Drug

Objective: To determine the efficacy of Letrozole as a first line drug in subfertile patients in term of pregnancy rate. Study Design: Case series study. Setting: OutpatientDepartment of Gynecology, Nishtar Hospital Multan. Period: May 2012 to December 2012.Material and methods: A total of 246 females with primary subfertility were enrolled in studyfrom gynecological outpatient department. Results: Mean age of the patients was 25.92 ±3.93years. 132 patients (54.0 %) had BMI of 2-25 kg/m2 and 101 patients (41%) had increasedof BMI 26-30 kg/m2 and 13patients (5%) were obese and had BMI of >30 kg/m2. 42 patients(17%) were illiterate. 54 patients (22%) were primary to middle and 62(25%) were matricand 88(36%) were FSC and > than FSC. 39(16%) patients had monthly income 10,000 and120(49%) patients had monthly income 10,000 -30,000 and 87(35%) patients had monthlyincome >30,000. Pregnancy was seen in 34% (83 patients). Conclusion: Aromatase inhibitors,Letrozole significantly increases pregnancy rate as a primary treatment in subfertility patients.

scholarly journals Pediatrics Infected with COVID-19: A Case Series Study on Pediatrics Hospitalized in a Referral Pediatric Hospital

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Houman Hashemian ◽  
Saeid Sadat Mansouri ◽  
Hamid Reza Badeli ◽  
Ebrahim Esmaili ◽  
Majid Asgharzadeh ◽  
...  
Keyword(s):  
Ct Scan ◽  
Clinical Laboratory ◽  
Treatment Strategies ◽  
Case Series ◽  
Pediatric Hospital ◽  
Laboratory Findings ◽  
Case Series Study ◽  
The Mean ◽  
Underlying Diseases ◽  
Series Study

Introduction. COVID-19 infection which is a novel pneumonia associated with coronavirus suddenly broke out in the world. The aim of this study is to analyze and summarize the clinical characteristics of pediatric patients who were hospitalized in a referral pediatric hospital because of COVID-19 infection. Materials and Methods. Twenty-one COVID-19 infection cases confirmed by clinical and laboratory findings who were hospitalized in our center from 20 February to 19 April 2020 were included. Demography information, clinical, laboratory, and radiological findings, and treatment strategies of patients were evaluated. Results. The mean age was 91.5 ± 68.38 months (1-225), and there were 12 (57.1%) boys and 9 (42.9%) girls. Fever ≥ 38 ° C was detected in 11 (52.4%) patients. Eleven (52.3%) patients had tachypnea, and 4 (19%) of them developed tachycardia. Nine CT scans (42.85%) demonstrated a halo sign, and patchy infiltration was seen in CT scan of 7 patients (33.33%). Furthermore, bilateral crazy-paving pattern was seen in CT scan of nine (42.85%) patients. We prescribed chloroquine in 8 (38.1%), oseltamivir in 8 (38.1%), Kaletra in 6 (28.6%), and Ribavirin in 1 (4.8%) of patients. Finally, four (19.04%) patients expired which one of them suffered from ARDS. Conclusions. We found out that boys might develop more severe cases of COVID-19, and this could be more common in school age. Manifestations might be milder than adults, and the most severe cases might be associated with underlying diseases. Also, the effectiveness of drugs in the treatment of this disease needs further study.

scholarly journals Volar Scaphoid Plating for Nonunion: A Multicenter Case Series Study

2020 ◽  
Vol 09 (03) ◽  
pp. 225-229
Author(s):  
Kevin Eng ◽  
Stephen Gill ◽  
Simon Hoy ◽  
Vivek Shridar ◽  
Natasha Van Zyl ◽  
...  
Keyword(s):  
Case Series ◽  
Visual Analogue Score ◽  
Rotational Stability ◽  
Volar Aspect ◽  
Number Of Patients ◽  
Case Series Study ◽  
Structural Graft ◽  
The Mean ◽  
Series Study

Abstract Background The volar scaphoid plate from Medartis (Medartis AG, Austrasse, Basel, Switzerland) is a variable angle titanium locking plate, preformed for the volar aspect of the scaphoid. It does not have compressive capability, and may act as a bridging device. It may provide an advantage over a compression screw where the pathoanatomy is less favorable to such a device with increased rotational stability. It may act as a buttress plate for correction of humpback deformity for example. It has been used in nonunions and with vascularized grafts. Questions Our study aims to assess the results of our patients with scaphoid nonunion treated with scaphoid volar plating over a larger number of patients. We aim to identify techniques to increase the success of plating. Methods Patients from our cohort were retrospectively reviewed. Operations were performed by three hand fellowship trained surgeons and in two centers. Inclusion involved a scaphoid plate procedure for a nonunion of the scaphoid with a minimum of 6 months of follow-up. Exclusions were those who had less than 6 months of follow-up. Data included demographics, patient-rated wrist evaluation (PRWE), a quick disabilities of the arm, shoulder, and hand (qDASH), visual analogue score, and range and grip. Radiology was reviewed. Results Thirty-two eligible patients were assessed. The mean age was 25 years (range 13–46), 2 were female and 15 were smokers. Mean follow-up postsurgery was 18 months. Twenty-nine of 32 patients united (90.6%) on computed tomography scan. Clinical assessment was performed in the 25 patients. The mean qDASH score was 12.5 (range 0–42) and mean PRWE was 11 (range 0–54). The mean arc of motion was 115 degrees. The mean grip strength was 39 kg compared with 41 kg on the nonoperated side. Conclusion We postulate that the plate acts like an internal bridging device, acting over a small distance, and inherent stability of the construct with structural graft and accurate reduction prior to plating is advantageous. Potential problems include plate impingement on the volar lip of the radius, particularly when trying to plate more proximal fractures. Ideally, it is utilized for mid to distal waist fractures.

scholarly journals Safety and Efficacy of Pterygium Extended Removal Followed by Extended Conjunctival Transplant for Recurrent Pterygia

2021 ◽  
Author(s):  
Walid Allam ◽  
Ahmed Roshdy Alagorie ◽  
Mohammed Nasef ◽  
Molham El-Bakary
Keyword(s):  
Donor Site ◽  
Case Series ◽  
Surgical Excision ◽  
Safety And Efficacy ◽  
Case Series Study ◽  
Corrected Distance Visual Acuity ◽  
The Mean ◽  
Prospective Case Series ◽  
Series Study

Abstract Purpose To study the safety and efficacy of pterygium extended removal followed by extended conjunctival transplant for recurrent pterygia. Methods Thirty-three eyes of 33 subjects with recurrent pterygia were enrolled in this prospective case series study. Pterygium extended removal followed by extended conjunctival transplantation was done for all subjects. One surgeon (WA) performed all surgeries. All subjects completed follow-up for at least 12 months and were evaluated for recurrence and complications. Results The mean age of the participants was 41.2 ± 10.3 years (range 22–60), 7 females (21.2%). The mean duration of follow-up was 25.64 ± 9.24 months (range 12–43). Corrected distance visual acuity (decimal notation) improved from 0.69 ± 0.22 (range 0.2–1.0) at presentation to a 1-year postoperative value of 0.83 ± 0.2 (range 0.3–1.0). No recurrence was reported in all subjects throughout the follow-up period. Transient graft swelling was recorded in 14 cases (42.4%) and resolved in all cases by the first week. All patients developed variable degrees of transient postoperative diplopia that resolved completely by the first 6 weeks. Donor site granuloma developed in 4 cases (12.1%). Spontaneous resolution was observed in 3 cases, while in one case, surgical excision was performed 2 months after the procedure. Conclusions In this study of eyes with recurrent pterygia, pterygium extended removal followed by extended conjunctival transplant was found safe and effective with no recurrence and minimal postoperative complications.

scholarly journals Five Years Prospective Study on Implant Failure and Marginal Bone Remodeling Expected Using Bone Level Implants with Sandblasted/Acid-Etched Surface and Conical Connection

2021 ◽  
Author(s):  
Marco Tallarico ◽  
Aurea Immacolata Lumbau ◽  
Silvio Mario Meloni ◽  
Irene Ieria ◽  
Chang-Joo Park ◽  
...  
Keyword(s):  
Bone Remodeling ◽  
Case Series ◽  
Insertion Torque ◽  
Case Series Study ◽  
The Mean ◽  
Prospective Case Series ◽  
One Year ◽  
The One ◽  
Series Study

Aim: the purpose of the present prospective, case series study were to report implant survival rate and marginal bone remodeling expected five years after loading using dental implants placed in in the daily practice. Material and Methods: this research was designed as an open-cohort, prospective case series study. Any completely or partially edentulous patients scheduled to receive at least one bone leve were considered eligible for this study. Primary outcomes were: cumulative implant (ISR) and prosthetic (PSR) survival rates, and any complications experienced up the five years follow-up. Secondary outcomes were: marginal bone remodeling, implant insertion torque, implant stability quotient (ISQ), and thickness of gingival biotype. Results: ninety consecutive patients (34 males and 56 females; mean age 53.2&plusmn;15.4 years; range of 24&ndash;81 years), 243 implants were placed and followed for at least five years after loading (mean of 65.4&plusmn;3.1 months; range of 60&ndash;72 months). The mean implant insertion torque was 42.9&plusmn;4.8 Ncm (range from 15 to 45 Ncm). Overall, 83.5% of the implants (n=203) were placed with an insertion torque between 35 and 45 Ncm. At the one year follow-up, no drop-outs were recorded, but 17 patients (18.9%) with 18 restorations (12.6%) delivered on 34 implants (14%) were lost at the five years examination. At the five-year examination, six implants failed in six patients, resulting in a cumulative ISR of 97.5%. At the five-year follow-up, four prostheses failed (2.8%) resulting in a cumulative PSR of 97.2%. At the five-year examination, five complications were reported by five different patients, resulting in a prosthetic success rate of 96.5%, measured at patient level. Five years after loading, mean MBL was 0.41 &plusmn; 0.30 mm (95% CI: 0.26&ndash;0.34). Difference from the one year data was 0.04 &plusmn; 0.19 mm (95% CI: 0.01&ndash;0.07). The mean ISQ value at implant placement was 71.6 &plusmn; 5.5 (range of 45&ndash;88). Six months later, the mean ISQ was 76.7 &plusmn; 4.4 (range of 66&ndash;89). The difference was statistically significant (P=0.0001). Statistically significant higher MBL was found for smokers, and patient with thin gingival biotype. Conclusions: High implant survival and success rates could be expected with stable marginal bone remodeling up to five years after loading. Smoking and thin tissue biotype were the most important variabilities associated with higher MBL. Further research are needed to confirm these results.

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