scholarly journals SUBFERTILE PATIENTS

2016 ◽  
Vol 23 (02) ◽  
pp. 152-155
Author(s):  
Shazia Abbass ◽  
Ejaz Ahmed ◽  
Iram Shabbir

Objective: To determine the efficacy of Letrozole as a first line drug in subfertile patients in term of pregnancy rate. Study Design: Case series study. Setting: OutpatientDepartment of Gynecology, Nishtar Hospital Multan. Period: May 2012 to December 2012.Material and methods: A total of 246 females with primary subfertility were enrolled in studyfrom gynecological outpatient department. Results: Mean age of the patients was 25.92 ±3.93years. 132 patients (54.0 %) had BMI of 2-25 kg/m2 and 101 patients (41%) had increasedof BMI 26-30 kg/m2 and 13patients (5%) were obese and had BMI of >30 kg/m2. 42 patients(17%) were illiterate. 54 patients (22%) were primary to middle and 62(25%) were matricand 88(36%) were FSC and > than FSC. 39(16%) patients had monthly income 10,000 and120(49%) patients had monthly income 10,000 -30,000 and 87(35%) patients had monthlyincome >30,000. Pregnancy was seen in 34% (83 patients). Conclusion: Aromatase inhibitors,Letrozole significantly increases pregnancy rate as a primary treatment in subfertility patients.

2018 ◽  
Vol 5 (2) ◽  
pp. 420
Author(s):  
Subhash N. Halbhavi ◽  
Mahantayya Ganjigatti ◽  
Shrikant B. Kuntoji ◽  
Mohammedgouse A. Karikazi

Background: A thyroid enlargement whether diffuses or in the form of nodules have to be investigated to rule out neoplasm. FNAC is the first line of investigation. USG and TFT are also used. The cases which are at high risk are considered for surgery. Aims and objectives of the study was the clinical presentation of thyroid swellings, incidence of various thyroid swelling, benign versus malignant lesion and to correlate the clinical diagnosis with that of pathological diagnosis.Methods: A case series study of 60 patients attending surgical OPD IPD with symptoms of thyroid in SNMRC and HSK hospital Bagalkot between 1-1-2015 to 30-6-2016. After detailed history thorough, clinical examination was carried out all the patients underwent routine investigations TFT FNAC USG neck. Few patients underwent surgery and all the thyroid specimens were sent for HPE and the clinical diagnosis is correlated with that of pathological diagnosis.Results: Of 60 cases female to male ratio was 9:1. The age group involved is between 31-40 years (31.67%). Duration of goiter is less than one year in 60% of cases. The chief complaint was swelling in front of the neck 100%. Duration of swelling ranged from 15 days to 15 years. Toxic features were present in 18.33% of cases, but after TFT the toxic cases were only 6.67%. Most of the patient showed colloid goiter (43.33%) on FNAC. Out of 60 cases only 22 cases did undergo surgery histopathological specimen were colloid versus nodular goiter in 81.88% out of 22 cases only.Conclusions: Thyroid swellings are common in females they occur in 3rd and 4th decade most commonly. FNAC is very useful in the diagnosis. The main indications of surgery are cosmetic problems, pressure effect symptoms are suspicion of malignancy.


2018 ◽  
Vol 25 (08) ◽  
pp. 1155-1159
Author(s):  
Muhammad Sameer Khulsai ◽  
Muhammad Imran ◽  
Atiq Ahmed Khan ◽  
Syed Ijlal Ahmed ◽  
Qazi Muhammad Zeeshan ◽  
...  

Background and Objectives: To analyze the functional outcome of open doorlaminoplasty (ODL) for the treatment of Cervical Ossified Posterior Longitudinal Ligament(OPLL). Study Design: Case series study. Setting: Civil Hospital Karachi. Period: 05 years,2013 to 2017. Material & Methods: 18 patients (15 Male, 3 Female) underwent ODL for cervicalOPLL, over a period of 5 years. Pre-operative & post- operative degree of myelopathy wasassessed using Nurick grading score. Patients with Nurick grade > 2 were included in study.MRI compatible titanium micro plates & screws were used. Instability was assessed by X-rayCervical Spine obtained 6 weeks post-operatively. Results: Mean age of presentation was 52years. 2 to 3 levels were involved in most cases. Mean operative time was 2 hours 30 minutes.Following Nurick grading 94.4% (n=17) improved by grade 1 or more, while in only 5.6%(n=1) it remained same. No instability or kyphotic deformity was seen on follow up X-rays.Conclusion: ODL is a safe & effective procedure for the treatment of multiple level OPLL. Itcan avoid complications related to the anterior approach (like unintentional durotomy & spinalcord injury) and diminished the possibility of instability & kyphotic deformity associated withlaminectomy alone.


2012 ◽  
Vol 19 (05) ◽  
pp. 672-678
Author(s):  
ATIF SITWAT HAYAT ◽  
MOHAMMAD ADNAN BAWANY ◽  
FURRUKH NAZ SILAWAT ◽  
Mohammad Akber Memon

Background: Porto-systemic encephalopathy (PSE) is a common medical emergency at our settings due to increasedprevalence of chronic liver disease. Objective: To determine frequency of common precipitating factors in patients having porto-systemicencephalopathy (PSE) at tertiary care settings in Hyderabad. Study design: Descriptive case series study. Setting: Department of MedicineIsra University Hospital Hyderabad. Period: 1st April 2011 to 31st December 2011. Methods: A total 100 patients manifesting clinical featuresof PSE were included in this study by non-probability convenience sampling. The data was evaluated in statistical program SPSS version 16.Results: As 100 patients with PSE were enrolled in the current study, out of these 96 patients have precipitating factors involved while only 4patients have no such factors. Out of these 96 patients, 36 patients have only single risk factor found while in 64 cases multiple factors wereimplicated. Constipation, infections (except SBP) and renal impairment were noted in 36%, 24% and 22% respectively. Conclusions:Constipation, infections (except SBP) and renal impairment were the most common precipitating factors of porto-systemic encephalopathy inour study. Hence priority should be given to them in terms of hospital funds, medicines and human efforts.


2010 ◽  
Vol 17 (01) ◽  
pp. 101-104
Author(s):  
HAJI KHAN KHOHARO ◽  
F ATI MA QURESHI ◽  
SHUAIB ANSARI ◽  
Rizwan Javed

Objective: The study was conducted to determine the frequency of Chloroquine-resistant Plasmodium falciparum. Subjects& Methods: This was a descriptive case series study conducted at Muhammad Medical College Mirpurkhas & Liaquat University HospitalHyderabad/ Jamshoro, from January 2007 to December 2007. Total 160 patients with acute attack of fever were selected & studied who fulfilledthe inclusion criteria. The WHO extended test was done by giving 25 mg/kg body weight of Chloroquine base over 3 days. The interpretationof the test was done as per criteria laid down by WHO. Results: Out of one hundred sixty, 110 (68.75%) were males and 50 (31.25%) werefemales with ratio of 2.2:1. The age range 16-45 years with mean 28±12 years. Seventy one patients (44.375%) were Chloroquine sensitive.Chloroquine-resistance (CQR) Rl, Rll & both Rl Rll noted were 28.125%, 15.645% & 43.75% respectively. The CQR- R III was not observedin our study. Conclusions: In view of this situation, more organized and thorough studies must be conducted to elucidate the epidemiology,geographic-distribution & degree of Chloroquine resistance. And the local strategies be made to overcome this problem and to assess the needfor changing the first line drug.


2010 ◽  
Vol 17 (04) ◽  
pp. 573-577
Author(s):  
SADIA HAMEED ◽  
AKRAM MALIK ◽  
SAIRA BILAL ◽  
SHAHID RIAZ DOGAR ◽  
SHAZIA ASLAM

Objectives: Analysis of the pattern of prostatic disease in Faisalabad. Design of Study: Case series study. Setting: Department of Pathology, University Medical and Dental College (UM&DC) and Meezan Laboratory (ML). Period: Duration of the study is three years. Methods and Materials: All prostatic specimens presenting to the Pathology department at the UM&DC and ML for histopathology were included. Results: During this period 540 prostatic biopsies were examined. The mean age of the patients was 67 years. Out of these 467(86.5%) were benign, 2 (0.3%) had prostatic intraepithelial neoplasia and 71 (13.5%) were malignant. All the cases of malignancies were adenocarcinomas. Most of them were well differentiated (Gleason’s score 2-4). The highest incidence of hyperplasia and malignancy occurred between 60-70 years of age. Conclusions: The incidence of prostatic cancer is on the rise and measures should be taken for early detection.


Author(s):  
Amir Moeintaghavi ◽  
Negar Azami ◽  
Mohammad Sadegh Zohrevand ◽  
Farid Shiezadeh ◽  
Hamid Jafarzadeh ◽  
...  

2018 ◽  
Vol 45 (4) ◽  
pp. 261-266
Author(s):  
Jorge Luis Alfredo Herrera Ariza ◽  
Mario Alejandro Villabón ◽  
Ángela Carolina Rojas Ruiz ◽  
Iván Fernando Moncada

Objetivo: Determinar los agentes microbianos más frecuentes en pacientes de UCI con diagnóstico de sinusitis nosocomial en el Hospital de San José, período de dos años. Diseño: Estudio observacional tipo serie de casos. Materiales y métodos: Se incluyeron pacientes mayores de 18 años con una estancia hospitalaria mayor a 48 horas, que desarrollaron sinusitis nosocomial de acuerdo a los criterios de los Centers for Disease Control (CDC). Uso de dos técnicas: punción y lavado de seno maxilar. Resultados: 19 pacientes que cumplen los criterios de sinusitis nosocomial. Edad promedio 55 años, predominio sexo masculino. El 94.7% tuvo sonda orogástrica, 89.5% intubación orotraqueal y 89.5% ventilación mecánica. Hubo aislamiento polimicrobiano de gram positivos, gram negativos, anaerobios y hongos. La mortalidad en UCI fue 32%. Conclusiones: Se presenta una adecuada sensibilidad al tratamiento con vancomicina y piperacilina tazobactam en esta patología. El rendimiento diagnóstico es igual al realizar lavado y punción del seno maxilar.Objetive: To determine the microbial agents on UCI patients who have beendiagnosed with nosocomial sinusitis at the San Jose Hospital, (Bogota, Colombia) in a two-year period. Design: Case series study. Materials and methods: Patients who were older than 18-year olds, with a hospitalization longer than 48 hours who developed nosocomial sinusitis, according to the criteria established by the Centers for Disease Control (CDC) were included. Two techniques were employed for data collection: puncture and maxillary sinus wash. Results: 19 patients fulfill the criteria requirements for nosocomial sinusitis. Average age was 55 years old. Population mostly was composed by male individuals. 94.7% had a gastric tube intervention; 89.5% had tracheal intubation 89.5% mechanical ventilation. Polymicrobial isolation with gram positive, gram negative, anaerobic and fungi were identified. Mortality in critical care unites was 32%. Conclusions: An adequate sensitivity to treatment with vancomycin and piperacillin tazobactam was evidenced in this pathology.To perform a washing or maxillary sinus puncture had the same efficiency fordiagnosing this disease.


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