scholarly journals Effect of Addition of Black Cumin Seed Oil (Nigella sativa) as a Source of Omega-6 on Cork Albumin Powder (Channa Striata) for Wound Closure

2020 ◽  
Vol 10 (7) ◽  
pp. 656-662
Author(s):  
Dwi Inayatur Rohmah ◽  
Eddy Suprayitno
Keyword(s):  
Wound Closure ◽  
Seed Oil ◽  
Nigella Sativa ◽  
Black Cumin ◽  
Omega 6 ◽  
Channa Striata ◽  
Black Cumin Seed ◽  
Cumin Seed ◽  
Black Cumin Seed Oil

scholarly journals Formulasi dan Uji Aktivitas Antibakteri Sediaan Emulgel Minyak Biji Jintan Hitam (Nigella sativa L.) terhadap Bakteri Staphylococcus epidermidis

2021 ◽  
Vol 11 (2) ◽  
pp. 121-131
Author(s):  
Nesa Agistia ◽  
Melzi Oktaviani ◽  
Wildan Khairi Mukhtadi ◽  
Della Ariska
Keyword(s):  
Antibacterial Activity ◽  
Staphylococcus Epidermidis ◽  
Seed Oil ◽  
Nigella Sativa ◽  
Positive Control ◽  
Diffusion Method ◽  
Black Cumin ◽  
Black Cumin Seed ◽  
Cumin Seed ◽  
Black Cumin Seed Oil

Acne is a skin problem that often occurs, one of the causes is the bacterium Staphylococcus epidermidis. Black cumin seed oil (Nigella sativa L.) can be used as an antibacterial because it contains thymoquinone and α-pinene. This study aims to obtain black cumin seed oil emulgel preparations that has antibacterial activity against Staphylococcus epidermidis. The preparations were formulated with concentrations of 3% (FI), 5% (FII), and 7% (FIII). Evaluation of the preparation was carried out for eight weeks including organoleptic tests, spreadability, emulsion type, pH, viscosity, homogeneity. Antibacterial activity tests was carried out using the well-diffusion method. The results of the evaluation of all three formulas obtained showed a semi-solid consistency, light brown in color, characteristically smelled of black cumin seed oil, stable, M/A emulsion type, homogeneous, non-irritating, pH FI = 4.51-4.95, FII = 4.72-4.99, FIII = 4.57-4.87, dispersion FI = 3.2-3.8 cm, FII = 3.3-3.9 cm, FIII = 3.4-3.9 cm, viscosity FI = 10.7-26.1 Ns/m2, FII = 11.2-32.0 Ns/m2, FIII = 11.5-34.1 Ns/m2. The antibacterial activity test showed the inhibitory power of FI 11,66±0,09 mm, FII 14.48±0.03 mm, FIII 17.35±0,.8 mm, lower than the positive control (clindamycin). All three black cumin seed oil emulgel preparations obtained met the physical requirements and had bacterial inhibition (p

scholarly journals Physiochemical properties of Saudi Nigella sativa L. (‘Black cumin’) seed oil

OCL ◽  
2021 ◽  
Vol 28 ◽  
pp. 11
Author(s):  
Nesrain Farhan ◽  
Nadia Salih ◽  
Jumat Salimon
Keyword(s):  
Linoleic Acid ◽  
Vitamin E ◽  
Volatile Compounds ◽  
Seed Oil ◽  
Nigella Sativa ◽  
Physiochemical Properties ◽  
Black Cumin ◽  
Black Cumin Seed ◽  
Cumin Seed ◽  
Black Cumin Seed Oil

The seeds of Nigella sativa L. (Ranunculaceae), commonly known as black cumin seeds and Habat Al-barkah in Saudi Arabia, are used extensively for flavouring and medicinal purposes. This work reported the study of physiochemical properties of Saudi black cumin seed oil (BCSO). The results of hexane extraction showed that black cumin seeds are rich in oil (43.7%). All the oil samples show high saponification values and low unsaponification values. High iodine values (122.7 mg/100 g) showed high degree of unsaturation (86%) for Saudi BCSO with about 60% of dominant linoleic acid (C18:2). The volatile compounds presence in Saudi BCSO were extracted using steam distillation method and analyzed using gas chromatography mass spectrometer (GC/MS). The results showed that the volatile compounds such as p-cymene (31.50 ± 0.51%) and thymoquinone (25.35 ± 0.37%) were dominantly high in Saudi BCSO. Other compounds such as 3,5-dimethyl cyclohexanol, α-thujene, carvacrol, paeonol and longifolene were also present. Vitamin E was analyzed using High performance liquid chromatography (HPLC)-fluorescence method. The total concentrations of vitamin E were 451 ppm. The Saudi BCSO showed high content of linoleic acid (59.8%). The HPLC results showed that major triacylglycerols (TAGs) of Saudi BCSO were 1-oleoyl-2,3-dilinoleoylglycerol (OLL; 37.7 ± 0.4%) and 1,2,3-trilinoleylglycerol (LLL; 35.9 ± 0.3%). On the other hand, minor TAGs present were 1-palmitoyl-2,3-dilinoleylglycerol (PLL; 6.7 ± 0.9%), 1,2,3-trioleylglycerol (OOO; 6.4 ± 0.5%) and 1,2-dioleyl-3-linoleylglycerol (OOL; 5.7 ± 1.1%). The Saudi BCSO exhibited specific physicochemical properties and might be used for medicinal applications.

Effect of Black Cumin Seed Oil (Nigella sativa) on Enhancement of Immunity in the Climbing Perch, Anabas testudineus

2015 ◽  
Vol 6 (6) ◽  
pp. 331-339 ◽  
Author(s):  
Aisha Khatun ◽  
M. Hossain ◽  
M. Rahman ◽  
M. Alam ◽  
Farzana Yasmin ◽  
...  
Keyword(s):  
Seed Oil ◽  
Nigella Sativa ◽  
Anabas Testudineus ◽  
Black Cumin ◽  
Climbing Perch ◽  
Black Cumin Seed ◽  
Cumin Seed ◽  
Black Cumin Seed Oil

scholarly journals A case study on in vitro investigations of the potent biological activities of wheat germ and black cumin seed oil

2015 ◽  
Vol 39 ◽  
pp. 801-812 ◽  
Author(s):  
Didem AĞ ŞELECİ ◽  
Zinar Pınar GÜMÜŞ ◽  
Murat YAVUZ ◽  
Muharrem ŞELECİ ◽  
Rebecca BONGARTZ ◽  
...  
Keyword(s):  
Wheat Germ ◽  
Seed Oil ◽  
Biological Activities ◽  
Black Cumin ◽  
Black Cumin Seed ◽  
Cumin Seed ◽  
Black Cumin Seed Oil

scholarly journals Black cumin seed oil increase leucocyte and CD4Thelper number in sprague-dawley rats induced with dimethylbenzanthracene

2019 ◽  
Vol 8 (2) ◽  
pp. 238
Author(s):  
Titiek Hidayati ◽  
Akrom Akrom ◽  
Indrayanti Indrayanti ◽  
Sagiran Sagiran
Keyword(s):  
Cell Count ◽  
Seed Oil ◽  
Corn Oil ◽  
Sprague Dawley ◽  
Black Cumin ◽  
Th Cell ◽  
Group I ◽  
Black Cumin Seed ◽  
Cumin Seed ◽  
Black Cumin Seed Oil

<p>Cigarette smoke contains 7, 12 dimethylbenzanthracene (DMBA). Metabolic of DMBA is immunosuppressive. Black cumin seed oil (BCSO) is an immunomodulation. The aim of this study was to determine the effect of BCSO on leukocyte, CD4Th and CD4CD25Treg in Sprague-Dawley (SD) mice induced with DMBA. The 96 SD rats were divided into 8 groups of 12. Group I received aquabidest and standard feeding. Groups II, III and IV received BCSO (an equivalent of 6.8, 68 and 136 mg/kg BW / day thymoquinone, respectively). Group V received thymoquinone (50 mg / kg BW / day) and group VI received tamoxifen (60 mg / kg BW). Group VII (DMBA) was induced with DMBA (10x20mg / kg BW for 5 weeks). Group VIII received standard feeding and corn oil treatment. In the third week, all groups began to be induced with DMBA (20 mg/kg BW twice per week for five weeks). Data collection of leukocytes, CD4Th and CD4CD25Treg was performed at week 27th. The mean difference of CD4Th and CD4CD25Treg counts between groups was calculated with one way ANOVA. Results: The administration of BCSO, thymoquinone, and tamoxifen had increased leukocytes and CD4 Th cell count. The CD4Th cell count of the treatment groups was higher than that of the DMBA group (p &lt;0.05). BCSO equivalent doses of 6.8 and 68 mg/kg BW / day thymoquinone showed immunoprotective effects. Conclusion: It can be concluded that the BCSO administration at doses of 6.8 and 68 mg/kg BW / day shows immunoprotective effects due to DMBA induction.</p>

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