scholarly journals Patient outcomes in integrated HIV and non-communicable disease models of care: a scoping review

Author(s):  
Blessings Gausi ◽  
Paul Otiku ◽  
Nisha Jacob ◽  
Tolu Oni
2021 ◽  
Vol 3 (1) ◽  
pp. 65-71
Author(s):  
Virna Wulandari ◽  
Siti Annisa Devi Trusda ◽  
Rika Nilapsari

Diabetes melitus (DM) merupakan penyakit tidak menular dengan insidensi terus meningkat setiap tahunnya. Salah satu komplikasi DM tersering adalah nefropati diabetik yang ditandai dengan albuminuria. Sodium glucose co-transporter (SGLT-2) inhibitor merupakan golongan obat antidiabetik yang bersifat insulin independen dan diharapkan menurunkan kejadian kerusakan fungsi ginjal. Kurangnya penelitian dan informasi obat golongan ini di Indonesia menyebabkan peneliti melakukan penelitian dengan tujuan mengetahui efektivitas pemberian obat golongan SGLT-2 inhibitor pada pasien DM tipe 2 terhadap penurunan kejadian albuminuria. Metode yang digunakan dalam penelitian ini adalah scoping review, dengan bahan penelitian artikel dari jurnal internasional yang memenuhi kriteria inklusi dan eksklusi. Artikel ini kemudian diseleksi menggunakan diagram PRISMA dengan mempertimbangkan Population (DM tipe 2), Intervention (pemberian SGLT-2 inhibitor), Comparison (plasebo atau anti diabetik lain), Outcome (penurunan albuminuria), Study (RCT dan Cohort retrospective). Didapatkan dari 13 artikel bahwa obat SGLT-2 inhibitor yang digunakan bervariasi yaitu canagliflozon (6), empagliflozin (3), dapagliflozin (2), ertugliflozin (2), dan yang tersering digunakan adalah canagliflozin ditemukan pada 6 artikel (50%). Golongan obat SGLT-2 inhibitor memiliki kecenderungan yang sama, dapat ditoleransi dengan baik dan efektif dalam menurunkan kejadian albuminuria melalui mekanisme perubahan hemodinamik ginjal, dengan urin albumin-kreatinin rasio (UACR) sebagai parameter. Scoping ReviewSGLT-2 Inhibitors Effective to Reduce Albuminuria in Type 2 Diabetes Mellitus Diabetes mellitus (DM) is a non-communicable disease with an increasing incidence every year. One of the most common complications of DM is diabetic nephropathy which is characterized by albuminuria. Sodium-glucose co-transporter (SGLT-2) Inhibitors is a class of anti-diabetic drugs that are insulin-independent and expected to reduce the incidence of impaired kidney function. The aim of this study was to ensure the effectiveness of SGLT-2 inhibitor drug administration in type 2 DM patients to reduce the incidence of albuminuria. The method used is scoping review, with research articles from international journals sorted by the inclusion and exclusion criteria. These articles was selected using the PRISMA diagram by considering Population (DM type 2), Intervention (administration of SGLT-2 inhibitors), Comparison (placebo or other anti-diabetic), Outcome (decreased albuminuria), Study (RCT and retrospective cohort). It was obtained from 13 articles that the SGLT-2 inhibitor drugs used varied, canagliflozon (6), empagliflozin (3), dapagliflozin (2), ertugliflozin (2), and the most commonly used was Canagliflozin found in 6 articles (50%). The SGLT-2 inhibitor class of drugs has the same tendency, well-tolerated, and effective in reducing the incidence of albuminuria through the mechanism of renal hemodynamic changes, with urine albumin-to-creatinine ratio (UACR) as a parameter.


2022 ◽  
Vol 2 (1) ◽  
Author(s):  
A. Komuhangi ◽  
C. Jenkins ◽  
F. Nakaggwa ◽  
P. Agaba ◽  
F. Githinji ◽  
...  

Abstract Background The impact of informal caregiving is increasingly recognised as an important but often particularly neglected area of research in low and middle income countries. It is important to understand not only the effect of care on patient outcomes, but also the impact of caring on caregivers’ health and wellbeing. Methods Guided by the Arksey and O’Malley (Res Methodol 8:19–32, 2005) framework, this scoping review sought to collate and chart existing research on the needs, burdens and challenges experienced by caregivers in Uganda. Results The results of this review indicate that research focusing on the needs of caregivers for individuals with communicable disease, particularly HIV, has been well developed in Uganda, however, there is a lack of research on caregiving related to non-communicable diseases. Research has been dominated by small qualitative studies that are informative for understanding roles, burdens and contextually-specific aspects of care, but there is a need for larger studies that develop and test interventions designed to support the needs of caregivers. Conclusions Recurrent themes identified within this review, such as challenges in providing physical support and accessing treatment services, financial costs of care, psychological and mental health impacts and the experience of stigma, should help to inform well targeted and contextually-appropriate future research and interventions.


2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Rita Suhuyini Salifu ◽  
Khumbulani W. Hlongwana

Abstract Objectives To explore the mechanisms of collaboration between the stakeholders, including National Tuberculosis Control Program (NTP) and the Non-Communicable Disease Control and Prevention Program (NCDCP) at the national, regional, and local (health facility) levels of the health care system in Ghana. This is one of the objectives in a study on the “Barriers and Facilitators to the Implementation of the Collaborative Framework for the Care and Control of Tuberculosis and Diabetes in Ghana” Results The data analysis revealed 4 key themes. These were (1) Increased support for communicable diseases (CDs) compared to stagnant support for non-communicable diseases (NCDs), (2) Donor support, (3) Poor collaboration between NTP and NCDCP, and (4) Low Tuberculosis-Diabetes Mellitus (TB-DM) case detection.


Foods ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 1719
Author(s):  
Valentina Castillo ◽  
Fernanda Figueroa ◽  
Karoll González-Pizarro ◽  
Paz Jopia ◽  
Claudia Ibacache-Quiroga

Non-alcoholic fatty liver disease (NAFLD) is a chronic non-communicable disease, with a prevalence of 25% worldwide. This pathology is a multifactorial illness, and is associated with different risks factors, including hypertension, hyperglycemia, dyslipidemia, and obesity. Beside these predisposing features, NAFLD has been related to changes in the microbiota, which favor the disease progression. In this context, the modulation of the gut microbiota has emerged as a new therapeutic target for the prophylaxis and treatment of NAFLD. This review describes the changes in the gut microbiota associated with NAFLD and the effect of probiotics, prebiotics, and synbiotics on the gut microbiota, liver damage, anthropometric parameters, blood lipids, inflammation markers and insulin resistance in these patients.


Epidemiologia ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 14-26
Author(s):  
Anastasia I Kolomvotsou ◽  
Elena Riza

Over the past years there is a substantial wave of migrants and refugees all over the world. Europe accepts approximately one-third of the international migrant population with Greece, in particular, having received large numbers of refugees and migrants by land and sea since the beginning of the civil war in Syria. Diabetes, a non-communicable disease, is a global health problem, affecting people in developing countries, refugees and migrants, and its basic treatment tool includes self-management and education. In this pilot study, we organized educational, interactive group sessions for diabetic refugees, based on culture, health, and nutritional needs according to a questionnaire developed for the study. The sessions were weekly, for two months, in the context of primary healthcare, organized by a dietitian. Nine individuals completed the sessions, five of nine were diagnosed in Greece and seven of nine needed diabetes education. Their waist circumference was above normal and they were all cooking at home. Their nutritional habits improved by attending the sessions and the interaction helped their social integration. They all found the sessions useful, and felt more self-confident regarding diabetes control and healthier.


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