scholarly journals Clinicopathologic profile of sinonasal diseases in a tertiary hospital in Port Harcourt

2021 ◽  
Vol 10 (1) ◽  
pp. 012-018
Author(s):  
Matilda Uju Ibekwe ◽  
Edirirn Nosa Oghenekaro

Background: In a typical ear nose and throat clinic, disease conditions involving the nose and paranasal sinuses are not uncommon. The aim of this study is to determine the clinicopathologic profile of these diseases as it occurs in university of Port Harcourt teaching hospital. Methodology: A retrospective descriptive analysis of all patients with diagnosis of sinonasal disease that presented in the ear nose and throat surgery department of university of Port Harcourt teaching hospital within the period of 5years (from 2016 – 2020). Data retrieved were biodata, clinical features, diagnosis and treatment, these were all collated and analysed. Patients without complete records were excluded. The patients recruited had clinical diagnosis which was aided by radiological investigations and confirmed by histology. Result: A total of 68 patients were studied within the 5year period. There were 35males and 33 females. The mean age was 33.96+/_17.9 years. The age groups 11-20 and 41-50 were more affected. Rhinosinusitis was the commonest condition seen while inflammatory polyp was the commonest histologic diagnosis. Polypectomy with bilateral antrostomy was the commonly done surgery in 26.4% age. Conclusion: Disease of the nose and paranasal sinuses are commonly seen in ENT practice and rhinosinusitis is the commonest entity encountered with inflammatory polyp as the commonest histopathologic finding. Squamous cell carcinoma was the commonest malignant lesion seen occurring more in males. Age distribution of the diseases was statistically significant.

Author(s):  
Ibekwe Matilda Uju

<p class="abstract"><strong>Background:</strong> Nasopharyngeal cancer though an uncommon head and neck cancer, has high morbidity and mortality. It is a cancer that has peculiar geographic variations and hence has been studied by a lot of researchers globally. It however has not been studied as an entity in the South region. This study was to determine the clinical and histologic presentations as well as the prevalence of this disease in Port Harcourt.</p><p class="abstract"><strong>Methods:</strong> Hospital based retrospective review of all patients with confirmed diagnosis of nasopharyngeal cancer seen within the period of January 2014 to December 2018 at ENT Department University of Port Harcourt teaching hospital. The hospital records were the source of data. The demographics, clinical presentations, histology, investigations and outcome were all collated from the records and were analyzed with IBM SPSS version 25.  </p><p class="abstract"><strong>Results:</strong> Forty-one patients were studied with age range of 12-85 years. The mean age was 43±15.1 years. Male to female ratio was 1.2:1. Age 40 to 49 years was the most affected. Nasopharyngeal carcinoma was the commonest cancer recorded 68.29% followed by non-Hodgkin’s lymphoma 19.5%. Keratinizing squamous cell carcinoma was the commonest histologic type 43.9%. Commonest symptoms were neck swelling and nasal congestion 24.55%. Age distribution showed a statistical difference with histology of cancer. Mortality of 4.87 was recorded; the rest was lost to follow up.</p><p class="abstract"><strong>Conclusions:</strong> Nasopharyngeal carcinoma is the commonest cancer in the nasopharynx. It is significantly related with age. Patients often present late and it has very high morbidity and mortality rate. Attention to early vague symptoms will enhance early diagnosis, treatment therefore prognosis.</p>


Author(s):  
Ibekwe Matilda Uju ◽  
O. Ikenga Victor

Background: Bleeding from the nose is one of the commonest emergencies that could present in a typical ear, nose and throat clinic. It is often a frightful experience for both the patient and relations, especially in severe cases. Aim: To determine the aetiological profile, the management and outcome in patients that presented with epistaxis in University of Port Harcourt teaching hospital.  Patients and Methods: This was a retrospective study of patients with complaints of epistaxis that were managed within the period of January 2006 to January 2018 in the Ear, Nose and Throat (ENT) department, including referrals from the accident & emergency department and children emergency ward. Data on demographics, aetiology, associated clinical features, treatment modalities and outcome of such treatments were all collated. These were analyzed using IBM statistical package for social sciences SPSSversion 20and results presented in simple descriptive tables. Results: There were altogether 196 patients studied, 95 males and 101 females, giving a male to female ratio of 1:1.06.  The age range was from 1 to 81 years. Age group 30-39 was the most affected with 22.29% Aetiological factors were; hypertension in 9.2% trauma in 11.2%, idiopathic in most; 58.2%, chronic rhinosinusitis in 18.4%. Conservative medical therapy was the commonest treatment modality; 68.38%. Anterior nasal packing in 26.5% while 4.1% had posterior packing. Anterior aspect of the nose was the commonest site of bleed recorded in 160 cases. All the patients had a favourable outcome. Conclusion: Epistaxis in this environment still presents as a common emergency and in the majority of the case, the cause is not known, however, trauma appears to be one of the commonest cause implicated in our setting. The young adults appear to be the ones mainly affected.


Author(s):  
Ibekwe Matilda Uju ◽  
Anyama Ernest Ugonna

Background: It is not all facial nerve palsy that presents to the otorhinolaryngologist that is Bell’s palsy; therefore there is a need for proper evaluation of these patients. This study is to determine the pattern and prevalence of otorhinolaryngologic disorders associated with facial nerve paralysis. Aim: To determine the prevalence and pattern of otorhinological disorders implicated in facial nerve paralysis in University of Port Harcourt Teaching Hospital. Patients and Methods: Study design: This was a hospital-based descriptive study. The patients diagnosed with facial nerve paralysis seen in the Ear Nose and Throat surgery and Physiotherapy departments of the University of Port Harcourt Teaching Hospital (UPTH) from January 2014 to December 2018 were collated and those among them with associated otorhinolaryngological disorders were recruited and studied. Data on patient demographics, presenting complaints and ear nose and throat disorders were sought from the case files, clinic and ward registers. Data entry was done using Microsoft Excel and exported to United States CDC Epi-Info version 7 for data analysis. Frequency tables and appropriate charts were used to present data. Chi square statistics was performed to determine significant differences between demographics of the patients and category of facial nerve palsy patients at alpha level of 0.05. Results: 76 patients with facial nerve paralysis, twenty one of them were associated with ORL disorder giving a prevalence of 27.6%. Ages below 40 years were the most affected and a slight male preponderance. Acute and chronic otitis media were seen in 33.3% of these patients respectively while Ramsay hunt syndrome and otitis externa were seen in 9.5%. Age and incidence of ORL disorders in these patients had statistical correlation. Conclusion: ORL disorders associated with facial paralysis are still prevalent and otitis media appear to be the most common.


Author(s):  
Stella-Maris C. Egboh ◽  
Bolaji I. Otike-Odibi ◽  
Dasetima D. Altraide ◽  
Abimbola T. O. Awopeju

Dengue fever is a mosquito borne disease which can easily be missed or misdiagnosed in early stages as a result of poor surveillance, similarity with other febrile illness and unavailability of PCR necessary for its diagnosis. We hereby report a 44year old female nurse living around a bushy and swampy environment, who presented to university of Port-Harcourt teaching hospital (UPTH) with high grade fever of 1week duration, also developed joint pains, passage of coke colored urine, sensor neural deafness, hyperglycemia and petechial hemorrhage while on admission. Patient continued to have persistent fever despite having completed her anti-malaria and antibiotics, viral studies were subsequently done for her and she was found to have dengue virus. Patient was conservatively managed and discharged for follow-up in medical outpatient and Ear nose and throat clinic.


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