scholarly journals A Comparison of Various Data Reduction Procedures in a Multiple Sclerosis Sleep Study

2018 ◽  
Vol 1 (1) ◽  
pp. 15-28
Author(s):  
Aniqa Tasnim Hossain ◽  
Daria Trojan ◽  
John Kimoff ◽  
Andrea Benedetti
Keyword(s):  
Multiple Sclerosis ◽  
Sleep Quality ◽  
Data Reduction ◽  
Pittsburgh Sleep Quality Index ◽  
Sleep Time ◽  
Objective Measures ◽  
Subjective Sleep Quality ◽  
Sleep Study ◽  
Reduction Strategies ◽  
Lasso Method

Clinical studies often deal with datasets with numerous variables. As a result of the similarities between the variables, we frequently observe the presence of multicollinearity in the data. This study aimed to apply different data reduction strategies to sleep study variables in multiple sclerosis (MS) patients. The main objective was to use various data reduction strategies to explain a subjective measure of sleep quality (Pittsburgh Sleep Quality Index: PSQI) by the objective measures of sleep quality obtained during complete in-laboratory overnight polysomnography. Overall, we found that few objective measures of sleep quality were important in explaining the subjective PSQI, based on the results of various well-accepted statistical methods. Total sleep time was found to be the most important feature of objective sleep quality for explaining subjective sleep quality among all other investigated objective sleep quality variables in most of the approaches investigated in this study. The LASSO method for estimation worked best in terms of interpretability among all the approaches considered.

scholarly journals 234 Sleep quality during the coronavirus pandemic in a Brazilian family-based cohort

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A93-A94
Author(s):  
Tamara Taporoski ◽  
Felipe Beijamini ◽  
Francieli Ruiz ◽  
Sabrina Ahmed ◽  
Malcolm von Schantz ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Pittsburgh Sleep Quality Index ◽  
Subjective Sleep Quality ◽  
Full Sample ◽  
Rural Town ◽  
Heart Study ◽  
Longitudinal Comparison ◽  
Family Based ◽  
And Gender ◽  
Stratified Analysis

Abstract Introduction Early in the COVID-19 pandemic, Brazil adopted measures to minimize the spread of the virus, including quarantine orders where people only left home for essential business. This practice could negatively impact sleep by reducing exposure to daylight and physical activity. We examined subjective sleep quality in Baependi, a small rural town in Brazil during the COVID-19 quarantine order. Methods This sample is from the Baependi Heart Study, a family-based cohort of adults. Participants (n=800, 71% women, mean age 51.6±15.6 years) completed the Pittsburgh Sleep Quality Index (PSQI) early in the COVID pandemic (April-May, 2020). They were also asked about their compliance to the quarantine order (yes/no). We compared sleep between quarantined (QT) and not-quarantined individuals (NQT). Longitudinal data was obtained from a subsample of 417 individuals who also completed a pre-COVID PSQI between January, 2010 and September, 2014. Results Individuals compliant with the quarantine had worse sleep quality than non-quarantined individuals [QT PSQI= 6.1 (±3.9), NQT PSQI= 5.0 (±3.5), p<0.01]. Stratified analysis showed that differences in PSQI scores between QT and NQT was greater for women [QT = 6.4 (±4), NQT = 5.2 (±3.7), p<0.01] and older people [QT = 6.6 (±0.1), NQT = 5.5 (±3.3), p=0.02]. Associations were attenuated after adjusting for age and gender. PSQI components demonstrated a higher sleep latency for the QT group in the full sample (p=0.02), women (p<0.01) and young (<50 years, p=0.03). Sleep duration was shorter in the QT young subsample (p=0.03). QT women also reported lower sleep efficiency (p=0.01) and greater use of sleep medication than NQT women (p<0.01). In the longitudinal subsample, PSQI scores were significantly higher during COVID than pre-pandemic [COVID= 5.7 (±3.8), pre-COVID= 5 (±3.3), p<0.01]. The significant change in PSQI was only observed in the QT participants [COVID= 5.9 (±3.7), pre-COVID= 5.2 (±3.4), p<0.01] and not NQT [COVID= 5 (±3.7), pre-COVID= 4.5 (±3), p=0.12. Conclusion Individuals who quarantined during COVID-19 had worse sleep quality than individuals who did not quarantine. Longitudinal comparison demonstrated that participants who quarantined had worse sleep quality during COVID compared to before to the pandemic. Support (if any) NIH 1R01HL141881

scholarly journals Sleep quality of women with gynecological and breast cancer

2006 ◽  
Vol 14 (6) ◽  
pp. 872-878 ◽  
Author(s):  
Renata Furlani ◽  
Maria Filomena Ceolim
Keyword(s):  
Breast Cancer ◽  
Sleep Quality ◽  
Nursing Care ◽  
Pittsburgh Sleep Quality Index ◽  
Night Sleep ◽  
Subjective Sleep Quality ◽  
Subjective Sleep ◽  
Waking Up ◽  
Careful Assessment

Subjective sleep quality has been recognized as a valuable indicator of health and quality of life. This exploratory and descriptive study aimed at describing habitual sleep quality of women suffering from gynecological and breast cancer and comparing habitual versus sleep quality during hospitalization. Twenty-five women admitted in hospital for clinical treatment of cancer completed the Pittsburgh Sleep Quality Index (PSQI) within 72 hours after admission and again just before discharge. Fifty-two percent of subjects reported habitual bad sleep quality, and this proportion increased to 80% of subjects during hospital stay. Subjects indicated the following most frequent causes of night sleep disturbance: need to go to the toilet, waking up early and receiving nursing care during the night. Results point to the importance of including careful assessment of sleep quality and environment in nursing care planning for oncology patients, mainly during hospitalization.

scholarly journals 0515 Durability of Effects of Forehead Cooling on EEG Sleep Measures in Insomnia Patients from 2- to 30-Nights Use and 6-Month Safety Results

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A197-A197
Author(s):  
D Rippole ◽  
J Schirm ◽  
E Nofzinger
Keyword(s):  
Sleep Quality ◽  
Open Label ◽  
Safety Study ◽  
Subjective Sleep Quality ◽  
Sleep Study ◽  
Subjective Sleep ◽  
Sleep Studies ◽  
Open Label Trial ◽  
Study Participants ◽  
Over Time

Abstract Introduction Forehead cooling has previously been shown to improve EEG sleep measures in insomnia patients when applied for 2 nights. The current study assessed the durability of these effects after 30 days in home use as well as safety over 6 months in home use. Methods This was a prospective, open label trial involving 32 adults meeting diagnostic criteria for primary insomnia who previously had participated in a 2 night in lab EEG sleep study. In the current study, participants received an additional 30 nights in home treatment, then had repeat EEG sleep studies performed to determine if effects noted at 2 nights remained durable after 30 days. Subjects also participated in an open label 6-month in-home use safety study. Results Baseline, 2-night and 30-night EEG sleep measures for sleep latency were 80.7 ± 73.8, 25.3 ± 22.6, 26.2 ±25.8 minutes (2- to 30-night difference p=0.81, NS) and for sleep efficiency were 67.4 ± 15.7, 81.4 ± 11.2, 83.2 ± 13.6 (2- to 30-night difference p=0.18, NS). Subjective sleep quality (0-100 scale with 100=best) at baseline, 2-night and 30-nights were 29.8 ± 15.2, 48.3 ± 20.2, 57.2 ± 21.1 (linear improvements significant over time p<0.001). No adverse effects were seen across 6-months use. Conclusion Forehead cooling demonstrated durability of effects on EEG sleep measures from 2- to 30-nights use. Continuing improvements in subjective sleep quality when measured over time from baseline assessments to the end of the 30-night in-home use period were noted. Forehead cooling was safe over 6 months use in the home as evidenced by no serious device related adverse events. Support Ebb Therapeutics, Pittsburgh, PA 15222

scholarly journals Sleep deprivation and drowsiness of medical residents and medical students

2016 ◽  
Vol 43 (6) ◽  
pp. 438-444 ◽  
Author(s):  
KÁTIA SHEYLLA MALTA PURIM ◽  
ANA TEREZA BITTENCOURT GUIMARÃES ◽  
ANA CLÁUDIA KAPP TITSKI ◽  
NEIVA LEITE
Keyword(s):  
Medical Students ◽  
Sleep Quality ◽  
Sleep Deprivation ◽  
Pittsburgh Sleep Quality Index ◽  
Medical Residents ◽  
Undergraduate Medical Students ◽  
Subjective Sleep Quality ◽  
Subjective Sleep ◽  
Preventive Actions ◽  
Demographic Questionnaire

ABSTRACT Objective: to evaluate sleep quality and daytime sleepiness of residents and medical students. Methods: we applied a socio-demographic questionnaire, the Pittsburgh Sleep Quality Index (PSQI) and the Epworth Sleepiness Scale (ESS) to a population of residents and medical students. Results: hundred five residents and 101 undergraduate medical students participated. Residents presented higher mean PSQI (6.76±2.81) with poorer sleep quality when compared with undergraduates (5.90±2.39); Both had similar measures of sleepiness by ESS (p=0.280), but residents showed lower duration and lower subjective sleep quality. Conclusion: medical students and residents presented sleep deprivation, indicating the need for preventive actions in the medical area.

scholarly journals Sleep Quality and Depression in Vitiligo Patients

2020 ◽  
Vol 9 (1) ◽  
pp. 35-41
Author(s):  
Aynure Öztekin ◽  
Coşkun Öztekin
Keyword(s):  
Sleep Quality ◽  
Patient Group ◽  
Quality Index ◽  
Pittsburgh Sleep Quality Index ◽  
Healthy Control Group ◽  
Psychiatric Evaluation ◽  
Control Group ◽  
Subjective Sleep Quality ◽  
Dermatology Clinic ◽  
Healthy Control

Aim: Vitiligo is a common disorder that has not only dermatological but also psychological consequences. The aim of this study was to compare depression and sleep quality of vitiligo patients with healthy control group. Methods: In this cross-sectional case-control study, patients admitted to the Dermatology Clinic of Skin and Venereal Diseases Department of Hitit University Erol Olçok Education and Research Hospital between August 2018 and August 2019 were compared with healthy control group. The study included 67 patients and 69 control group participants who were matched for age, sex, marriage status, and education level. The subjects were asked to complete a sociodemographic data form, the Beck Depression Inventory, and the Pittsburgh Sleep Quality Index. Results: The median total Pittsburgh Sleep Quality Index score was higher in the patient group compared with the control group. The median scores for subjective sleep quality, sleep latency, and sleep disturbance were also higher in the patient group compared with the control group. A family history of vitiligo was present in 18 (26.9%) patients. The most common type was acrofacial vitiligo, which was present in 29 (43.3%) patients. Conclusions: Increased probability levels of depression and impaired sleep quality in vitiligo patients suggest that psychiatric evaluation and treatment should be provided for vitiligo patients as a part of a multidisciplinary approach in order to increase the success of the treatment. Keywords: Vitiligo, depression, sleep quality

scholarly journals Effect of kidney transplantation on sleep quality in patients admitted in ICU:a cross-section study in China

2019 ◽  
Author(s):  
Lu Long ◽  
Jia Liu ◽  
Jin Yan ◽  
Jian fei Xie ◽  
Huan Liu ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Sleep Quality ◽  
Linear Regression Analysis ◽  
Sleep Onset ◽  
Sleep Time ◽  
Middle Level ◽  
Sleep Disruption ◽  
Poor Sleep ◽  
Subjective Sleep Quality ◽  
Subjective Sleep

Abstract Background Although evidences showed that sleep disorder is common in patient with end stage renal disease (ESRD), less is known about their sleep quality after early post-kidney transplantation (kTx) especially in Intensive Care Unite (ICU). Thus, the purpose of this study is to investigate sleep quality of kTx recipients in ICU and explore factors related poor sleep, second, to measure the correlation of subjective sleep quality and sleep architecture assessed by PSG in kTx recipients. Methods This study recruited participants from ESRD patients registered in transplantation waiting list at the third xiangya hospital of central south university in China. Participants required to complete the Pittsburgh sleep quality index(PSQI) and demographic questionnaire as baseline data and received one night of Polysomnography (PSG) in the ICU within 96 hours of surgery, during which time sound and light data were monitored. After that Richards Campbell sleep questionnaires (RCSQ) also need completed. Results 26 participants self-reported sleep quality and sleep efficiency based on RCSQ was at middle level (49.2 ± 25.6mm), and 14/26(53.8%) kTx recipients in ICU were poor sleepers defined by RCSQ <50. PSG showed that most kTx recipients in ICU had shallow sleep with mainly stage 2 sleep time (80.90 ±70.10 min), lower total sleep time (136.50 ±86.41 min), higher awakening frequency after sleep onset (8.87 ±5.92 times) and long awaken time (94.67 ±75.09 min) when a sleep disruption occured. multiple linear regression analysis showed that self-reported noise and pain were the significant factor affecting sleep(P < 0.05).Conclusion Subjective sleep quality based on RCSQ scored better than objective one measured by PSG in kTx recipients, sleep disruption always remained a substantial problem and affected by self-reported noise and pain.

scholarly journals The relationship between fatigability and sleep quality in people with multiple sclerosis

2016 ◽  
Vol 2 ◽  
pp. 205521731668277 ◽  
Author(s):  
Mayis Aldughmi ◽  
Jessie Huisinga ◽  
Sharon G Lynch ◽  
Catherine F Siengsukon
Keyword(s):  
Multiple Sclerosis ◽  
Sleep Quality ◽  
Quality Index ◽  
Sleep Disturbances ◽  
Performance Test ◽  
Pittsburgh Sleep Quality Index ◽  
Self Report ◽  
Poor Sleep ◽  
Poor Sleep Quality ◽  
The Relationship

Background Perceived fatigue and fatigability are constructs of multiple sclerosis (MS)-related fatigue. Sleep disturbances lead to poor sleep quality, which has been found to be associated with perceived fatigue in people with MS (PwMS). However, the relationship between fatigability and sleep quality is unknown. Objective To explore the relationship between physical and cognitive fatigability with self-reported and objective measures of sleep quality in PwMS. Methods Fifty-one ambulatory PwMS participated in the study. Physical fatigability was measured by percent-change in meters walked on the six-minute walk test (6MWT) and in force exerted on a repeated maximal hand grip test. Cognitive fatigability was measured using response speed variability on the continuous performance test. Self-report sleep quality was measured using the Pittsburgh Sleep Quality Index, and objective sleep quality was measured using 1 week of actigraphy. Results Components of the Pittsburgh Sleep Quality Index and several actigraph parameters were significantly associated with physical fatigability and cognitive fatigability. However, controlling for depression eliminated the association between the sleep outcomes and cognitive fatigability and attenuated the association between the sleep outcomes and physical fatigability. Conclusion Poor sleep quality is related to fatigability in MS but depression appears to mediate these relationships.

scholarly journals Regular Caffeine Intake Delays REM Sleep Promotion and Attenuates Sleep Quality in Healthy Men

2021 ◽  
pp. 074873042110139
Author(s):  
Janine Weibel ◽  
Yu-Shiuan Lin ◽  
Hans-Peter Landolt ◽  
Christian Berthomier ◽  
Marie Brandewinder ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Rem Sleep ◽  
Sleep Time ◽  
Caffeine Intake ◽  
Sleep Regulation ◽  
Caffeine Consumption ◽  
Subjective Sleep Quality ◽  
Placebo Condition ◽  
Double Blind ◽  
Sleep Episode

Acute caffeine intake can attenuate homeostatic sleep pressure and worsen sleep quality. Caffeine intake—particularly in high doses and close to bedtime—may also affect circadian-regulated rapid eye movement (REM) sleep promotion, an important determinant of subjective sleep quality. However, it is not known whether such changes persist under chronic caffeine consumption during daytime. Twenty male caffeine consumers (26.4 ± 4 years old, habitual caffeine intake 478.1 ± 102.8 mg/day) participated in a double-blind crossover study. Each volunteer completed a caffeine (3 × 150 mg caffeine daily for 10 days), a withdrawal (3 × 150 mg caffeine for 8 days then placebo), and a placebo condition. After 10 days of controlled intake and a fixed sleep-wake cycle, we recorded electroencephalography for 8 h starting 5 h after habitual bedtime (i.e., start on average at 04:22 h which is around the peak of circadian REM sleep promotion). A 60-min evening nap preceded each sleep episode and reduced high sleep pressure levels. While total sleep time and sleep architecture did not significantly differ between the three conditions, REM sleep latency was longer after daily caffeine intake compared with both placebo and withdrawal. Moreover, the accumulation of REM sleep proportion was delayed, and volunteers reported more difficulties with awakening after sleep and feeling more tired upon wake-up in the caffeine condition compared with placebo. Our data indicate that besides acute intake, also regular daytime caffeine intake affects REM sleep regulation in men, such that it delays circadian REM sleep promotion when compared with placebo. Moreover, the observed caffeine-induced deterioration in the quality of awakening may suggest a potential motive to reinstate caffeine intake after sleep.

scholarly journals Does media use before bedtime affect the sleep of psychosomatic rehabilitation patients?

2020 ◽  
Vol 24 (4) ◽  
pp. 253-258
Author(s):  
Jasmin Faber ◽  
Indra Steinbrecher-Hocke ◽  
Peter Bommersbach ◽  
Angelika A. Schlarb
Keyword(s):  
Sleep Quality ◽  
Media Use ◽  
Total Sleep Time ◽  
Sleep Time ◽  
Sleep Efficiency ◽  
Subjective Sleep Quality ◽  
Psychosomatic Rehabilitation ◽  
Sleep Parameters ◽  
Rehabilitation Clinic ◽  
The Relationship

Abstract Objective Media use can affect sleep. However, research regarding various populations is sparse. The objective of this study was to examine the relationship between media use directly before bedtime and various sleep parameters in patients of a psychosomatic rehabilitation clinic. Methods Patients from a German psychosomatic rehabilitation clinic were tested regarding subjective sleep quality and insomnia symptoms based on questionnaires such as the Pittsburgh Sleep Quality Index (PSQI). Eligible patients also completed an additional sleep log over a period of 1 week. A total of 347 insomnia patients were enrolled, with a mean age of 49.77 years (range 22–64 years; median = 52 years). 57.5% of the patients were 50 years or older. Results Analysis showed that media use and various sleep diary parameters such as total sleep time (r = −0.386, p = 0.042; rTST2 = 0.149) and sleep efficiency (r = −0.507, p = 0.006; rSE2 = 0.257) were significantly associated. In detail, more media consumption was associated with less total sleep time and a lower sleep efficiency. The same result was found for media use and sleep efficiency on weekdays (r = −0.544, p = 0.002; rSE2 = 0.296), but not for other sleep parameters. However, media use time and subjective sleep quality were not significantly correlated, r = −0.055, p = 0.768. Conclusion This study, which is the first to examine the relation between media use and sleep in patients of a psychosomatic rehabilitation clinic, suggests a significant association between media use and sleep duration as well as sleep efficiency. However, more research is needed to investigate the relationship between media use and sleep in more detail, to increase patients’ quality of life and to incorporate these findings into the daily life of clinicians and therapists as well as into sleep hygiene education and sleep trainings.

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