scholarly journals Pathogenetic basis of venous thromboembolic complications as deuteropathies of COVID-19

2020 ◽  
Vol 96 (7) ◽  
pp. 485-490
Author(s):  
S. A. Fedorov ◽  
A. P. Medvedev ◽  
N. Yu. Borovkova ◽  
E. V. Taranov
Keyword(s):  
Health Care ◽  
Systemic Inflammatory Response Syndrome ◽  
Literature Review ◽  
Inflammatory Response ◽  
Distress Syndrome ◽  
International System ◽  
Morbidity And Mortality ◽  
Thromboembolic Complications ◽  
Venous Thromboembolic ◽  
Epidemiological Characteristics

Аt present, it can be noted without exaggeration that COVID-19 is the most serious challenge to the international system of practical health care in its recent history. Extremely high rates of morbidity and mortality dictate the need for a more detailed study of the pathogenetic aspects of the developing infectious disaster. In addition to respiratory distress syndrome, and systemic inflammatory response syndrome, COVID-19 is characterized by polyvalent disorders of the mechanisms of systemic hemostasis, which is reflected in the increase in the number of venous thromboembolic complications in the overall structure of morbidity and mortality. This literature review summarizes information on Covid-associated coagulopathy and its impact on changes in the clinical and epidemiological characteristics of venous thromboembolic complications.

Multiple arterial and venous thromboembolic complications in AL amyloidosis and cardiac involvement: a case report and literature review

Amyloid ◽  
2012 ◽  
Vol 19 (3) ◽  
pp. 156-160 ◽  
Author(s):  
Benjamin Freeman ◽  
J. Mark Sloan ◽  
David C. Seldin ◽  
Andrew J. Cowan ◽  
Frederick L. Ruberg ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Cardiac Involvement ◽  
Al Amyloidosis ◽  
Thromboembolic Complications ◽  
Venous Thromboembolic

scholarly journals Systemic inflammatory response syndrome in surgical patients with sepsis

2004 ◽  
Vol 132 (5-6) ◽  
pp. 182-186 ◽  
Author(s):  
Dragan Milic ◽  
Miljko Pejic ◽  
Sasa Zivic ◽  
Aleksandar Karanikolic ◽  
Slobodan Jovanovic ◽  
...  
Keyword(s):  
Systemic Inflammatory Response Syndrome ◽  
Inflammatory Response ◽  
Systemic Inflammatory Response ◽  
Current Understanding ◽  
Morbidity And Mortality ◽  
Surgical Patients ◽  
Font Color

Systemic inflammatory response syndrome and sepsis are common in surgically treated patients. Systemic inflammatory response syndrome represents a major factor of morbidity and mortality in these patients. The pathogenesis of these syndromes has been increasingly clarified. The objective of this review is to present an overview of our current understanding of the physiology underlying these conditions. <br><br><font color="red"><b> This article has been retracted. Link to the retraction <u><a href=http://dx.doi.org/10.2298/SARH1206269U>10.2298/SARH1206269U</a><u></b></font>

Heparin-Induced Fever: A Case Report and Literature Review

2019 ◽  
Vol 40 (5) ◽  
pp. 723-724 ◽  
Author(s):  
Jake Laun ◽  
Katie Laun ◽  
Adeel Farooqi ◽  
David J Smith
Keyword(s):  
Case Report ◽  
Systemic Inflammatory Response Syndrome ◽  
Literature Review ◽  
Inflammatory Response ◽  
Systemic Inflammatory Response ◽  
Burn Patients ◽  
Drug Induced ◽  
Documented Case

Abstract Burn patients are often plagued by fever due to the inflammatory nature of their injuries as well as the normal postoperative systemic inflammatory response syndrome. One etiology for fever, often not initially considered, is drug-induced fever. A rare cause of drug-induced fever is heparin with only one documented case reported in the literature. We present a case of heparin-induced fever in a patient who experienced a 32% total BSA friction burn after a motorcycle crash.

scholarly journals Bacterial purulent meningitis in children: is there a light at the end of the tunnel?

2021 ◽  
Vol 20 (4) ◽  
pp. 28-34
Author(s):  
A. A. Vilnits ◽  
N. V. Skripchenko ◽  
E. Yu. Gorelik ◽  
A. V. Astapova ◽  
K. V. Markova ◽  
...  
Keyword(s):  
Health Care ◽  
Literature Review ◽  
High Mortality ◽  
Risk Group ◽  
Morbidity And Mortality ◽  
Strict Adherence ◽  
Purulent Meningitis ◽  
Life Threatening ◽  
Heavy Burden ◽  
Meningitis In Children

Bacterial purulent meningitis is a life-threatening disease characterized by high mortality and severe consequences in survivors. Despite the modern possibilities of medicine, the disease continues to be a heavy burden on health care, the economy and society everywhere.Aim. To draw the attention of doctors to the problems associated with modern features of epidemiology, the consequences and possibilities of preventing bacterial purulent meningitis, especially in children, who constitute the main risk group for the development of this pathology.Literature review of Russian and foreign publications on the problem under consideration presented.Vaccination is recognized as one of the main tools for reducing morbidity and mortality from meningitis. Prophylactic vaccinations against N. meningitidis, Str.pneumoniae, H. influenzae, along with strict adherence to anti-epidemic measures in hospitals providing care to newborns, can help reduce the incidence of purulent meningitis in children and improve outcomes if they develop.

scholarly journals Outcomes of Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome due to COVID-19, lessons learned from the first wave of COVID 19

2021 ◽  
Author(s):  
Cameron Blazoski ◽  
Michael Baram ◽  
Hitoshi Hirose
Keyword(s):  
Septic Shock ◽  
Renal Failure ◽  
Acute Respiratory Distress Syndrome ◽  
Systemic Inflammatory Response Syndrome ◽  
Inflammatory Response ◽  
Extracorporeal Membrane Oxygenation ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Culture Negative

Introduction: Extracorporeal membrane oxygenation (ECMO) has been used as a refractory treatment for acute respiratory distress syndrome (ARDS) due to COVID-19, but there has been little evidence of its efficacy. We conducted this study to share our experience using ECMO as a bridge to recovery for ARDS due to COVID-19. Methods: All adult patients who were placed on ECMO for ARDS due to COVID -19 between April 2020 and June 2020 (during the first wave of COVID-19) were identified. The clinical characteristics and outcomes of these patients were analyzed with a specific focus on the differences between patients who survived to hospital discharge and those who did not. Results: 20 COVID-19 patients were included in this study. All patients were placed on veno-veno ECMO. Comparing between survivors and non-survivors, older age was associated with hospital mortality (p=0.02). The following complications were observed: renal failure requiring renal replacement therapy (35%, n=7), bacteremia during ECMO (20%, n=4),coinfection with bacterial pneumonia (15%, n=3), cannula site bleeding (15%, n=3), stroke (10%, n=2), gastrointestinal bleeding (10%, n=2), and liver failure (5%, n=1). The complications associated with patient mortality were culture positive septic shock (p=0.01), culture-negative systemic inflammatory response syndrome (p=0.01), and renal failure (p=0.01). The causes of death were septic shock (44%, n=4), culture-negative systemic inflammatory response syndrome (44%, n=4), and stroke (11%, n=1). Conclusions: Based on our experience, ECMO can improve refractory ARDS due to COVID-19 in select patients. Proper control of bacterial infections during COVID-19 immunomodulation therapy may be critical to improving survival.

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