scholarly journals Expression of Brain-Derived Neurotrophic Factor in the Brain of Depressed Mice: Systematic Literature Review

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Nur Azizah AS ◽  
Lysa Veterini ◽  
Hafid Algristian ◽  
Hotimah Masdan Salim
Keyword(s):  
Literature Review ◽  
Chronic Stress ◽  
Systematic Literature Review ◽  
Data Extraction ◽  
Stress Exposure ◽  
Inclusion Criteria ◽  
Literature Study ◽  
Experimental Animals ◽  
The Brain

Introduction: Chronic stress exposure plays a role as a risk factor for depression. In chronic stress, there is prunning of nerve cell dendrites so that depression becomes irreversible. Depression is caused by low serotonin (5-HT2) neurotransmitters in the postsynaptic cleft. Recent findings in experimental animals indicate that serotonergic preparations are required to increase serotonin levels in the synapse opening, thereby triggering the formation of new dendrites to make depression reversible. The different results when these preparations create resistance in cases of chronic depression and actually increase the risk of uncomfortable and even fatal side effects with long-term use.Methods: This Systematic Literature Review uses the PubMed and Google Scholar databases for the period 2015-2020. A total of 322 articles at the beginning of identification and those that met the inclusion criteria in this study were six articles.Results: The results of data extraction showed that the depression condition caused by various stressors resulted in BDNF levels in the hippocampus decreased significantly by p≤0.005.Conclusion: Based on the literature study, it was concluded that in depressive conditions, BDNF levels in the brain decreased.

A systematic literature review of incidence and predictors of headache and migraine in survivors of haemorrhagic stroke

2021 ◽  
Vol 17 (2) ◽  
pp. S26-S31
Author(s):  
Rachael Suzanne Jones
Keyword(s):  
Literature Review ◽  
Systematic Literature Review ◽  
Intracranial Haemorrhage ◽  
Human Subjects ◽  
Data Extraction ◽  
Haemorrhagic Stroke ◽  
True Incidence ◽  
Study Selection ◽  
Online Library

Background: Headache is a frequent symptom of stroke, but little is known about the true incidence of headache following a haemorrhagic stroke, or if there are any risk factors for experiencing stroke-related headache. A systematic literature review was undertaken to examine the burden of headache in haemorrhagic stroke. Methods: A systematic search of electronic databases, including MEDLINE, CINAHL, Embase, SAGE Premier, Wiley Online Library and Elsevier's ScienceDirect, with a date range of January 1990 to October 2016, for human subjects and written in English was performed. Study selection using clear criteria was undertaken, and data extraction and assessment of quality was performed. Results: Some five from a total of 27 studies met the selection criteria. A total of 483 participants were included. The pooled random effects model showed 0.5528 (95% CI 0.3756-0.7235) had headache at onset, and 0.3917 (95% CI 0.1156-0.7108) had long-term headaches. A pooled estimate for gender as a risk factor showed women had an odds ratio (OR) of 1.93 (95% CI 1.16-3.22). Conclusions: Approximately 55% of patients with intracranial haemorrhage will experience headaches at stroke onset, with a further 39% experiencing long-term headaches. Women are nearly twice as likely as men to experience headache post-intracranial haemorrhage.

scholarly journals Is there a sex difference in mortality rates for deaths occurring in paediatric intensive care units? Systematic literature review protocol

BMJ Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. e046794
Author(s):  
Ofran Almossawi ◽  
Amanda Friend ◽  
Luigi Palla ◽  
Richard Feltbower ◽  
Bianca De Stavola
Keyword(s):  
Intensive Care ◽  
Literature Review ◽  
Intensive Care Units ◽  
Systematic Literature Review ◽  
Data Extraction ◽  
Linkage Study ◽  
Paediatric Intensive Care ◽  
Admission Rates ◽  
Ethical Approval ◽  
Paediatric Intensive Care Units

IntroductionIn the general population, female children have been reported to have a survival advantage. For children admitted to paediatric intensive care units (PICUs), mortality has been reported to be lower in males despite the higher admission rates for males into intensive care. This apparent sex reversal in PICU mortality is not well studied. To address this, we propose to conduct a systematic literature review to summarise the available evidence. Our review will study the reported differences in mortality between males and females aged 0–17, who died in a PICU, to examine if there is a difference between the two sexes in PICU mortality, and if so, to describe the magnitude and direction of this difference.Methods and analysisStudies that directly or indirectly addressed the association between sex and mortality in children admitted to intensive care will be eligible for inclusion. Studies that directly address the association will be eligible for data extraction. The search strings were based on terms related to the population (children in intensive care), the exposure (sex) and the outcome (mortality). We used the databases MEDLINE (1946–2020), Embase (1980–2020) and Web of Science (1985–2020) as these cover relevant clinical publications. We will assess the reliability of included studies using the risk of bias in observational studies of exposures tool. We will consider a pooled effect if we have at least three studies with similar periods of follow up and adjustment variables.Ethics and disseminationEthical approval is not required for this review as it will synthesise data from existing studies. This manuscript is a part of a larger data linkage study, for which Ethical approval was granted. Dissemination will be via peer-reviewed journals and via public and patient groups.PROSPERO registration numberCRD42020203009.

Computer Science Unplugged: A Systematic Literature Review

2021 ◽  
pp. 004723952110188
Author(s):  
Ali Battal ◽  
Gülgün Afacan Adanır ◽  
Yasemin Gülbahar
Keyword(s):  
Literature Review ◽  
Computer Science ◽  
Systematic Literature Review ◽  
Computational Thinking ◽  
Thinking Skills ◽  
Inclusion Criteria ◽  
Relevant Research ◽  
Tangible Programming ◽  
Review Procedure ◽  
Research Studies

The computer science (CS) unplugged approach intends to teach CS concepts and computational thinking skills without employing any digital tools. The current study conducted a systematic literature review to analyze research studies that conducted investigations related to implementations of CS unplugged activities. A systematic review procedure was developed and applied to detect and subsequently review relevant research studies published from 2010 to 2019. It was found that 55 research studies (17 articles + 38 conference proceedings) satisfied the inclusion criteria for the analysis. These research studies were then examined with regard to their demographic characteristics, research methodologies, research results, and main findings. It was found that the unplugged approach was realized and utilized differently among researchers. The majority of the studies used the CS unplugged term when referring to “paper–pencil activities,” “problem solving,” “storytelling,” “games,” “tangible programming,” and even “robotics.”

scholarly journals Understanding Preferences for Coastal Climate Change Adaptation: A Systematic Literature Review

2021 ◽  
Vol 13 (15) ◽  
pp. 8594
Author(s):  
Angela Mallette ◽  
Timothy F. Smith ◽  
Carmen Elrick-Barr ◽  
Jessica Blythe ◽  
Ryan Plummer
Keyword(s):  
Literature Review ◽  
Systematic Literature Review ◽  
Place Attachment ◽  
Private Property ◽  
Public Support ◽  
Inclusion Criteria ◽  
Policy Makers ◽  
Coastal Adaptation ◽  
Significant Research ◽  
Response Policy

Lack of public support for coastal adaptation can present significant barriers for implementation. In response, policy makers and academics are seeking strategies to build public support for coastal adaptation, which requires a deeper understanding of peoples’ preferences for coastal adaptation and what motives those preferences. Here, we conduct a systematic literature review to understand preferences for coastal adaptation options and the factors influencing these preferences. Ninety peer-reviewed publications meet the inclusion criteria. The findings revealed that hard protection options were often the most frequently preferred, likely due to a desire to maintain current shoreline, for the protection of recreational spaces and private property, and a perceived effectiveness of hard protection options. Soft protection, including nature-based approaches, accommodation, and no action were the next most preferred options. Finally, retreat options were the least preferred, often due to strong place attachment. We identify twenty-eight factors that could influence preferences, with risk perception, place attachment, and financial considerations occurring most frequently in the literature. In the conclusion, we outline the most significant research gaps identified from our analysis and discuss the implication for adaptation research and practice.

scholarly journals Best Practices and Methodologies to Promote the Digitization of Public Services Citizen-Driven: A Systematic Literature Review

Information ◽  
2018 ◽  
Vol 9 (8) ◽  
pp. 197 ◽  
Author(s):  
Heloise Leão ◽  
Edna Canedo
Keyword(s):  
Literature Review ◽  
Best Practices ◽  
Systematic Literature Review ◽  
Public Services ◽  
Future Research ◽  
Private Companies ◽  
Digital Platform ◽  
Brazilian Government ◽  
Delivery Of Services

Governments at all levels have a mandate to provide services, protect society, and make the economy prosper. While this is a long-term goal, citizens are now expecting greater and faster delivery of services from government. This paper presents a systematic literature review of service digitization carried out by the governments of several countries, which was motivated by the lack of primary studies in the literature related to the identification of the processes and methodologies adopted by these governments and private companies to provide their services to the citizen. This work also contributes to the identification of best practices, technologies and tools used for the provision and evaluation of digitized services provided and how governments are evaluating the gains from digitization. These results of this systematic literature review serve as inputs to guide current and future research of the Brazilian Government in the construction of a digital platform for the provision of its services directed to the citizen, seeking to analyze their needs and improving the services currently provided.

scholarly journals INTEREST-FREE FINANCING IN AGRO-INDUSTRY: CONCEPTS, THEORIES, METHODS AND RESEARCH GAPS

2021 ◽  
Vol 9 (03) ◽  
pp. 84-94
Author(s):  
Kiki Yulianto ◽  
◽  
Sukardi a ◽  
Nastiti Siswi Indrasti ◽  
Sapta Raharja ◽  
...  
Keyword(s):  
Literature Review ◽  
Systematic Literature Review ◽  
State Of The Art ◽  
Secondary Data ◽  
Future Research ◽  
Literature Study ◽  
Research Gaps ◽  
The Road ◽  
Road Map ◽  
Conference Papers

Interest-free financing in agro-industry is an exciting topic that has been developed by many researchers, but there is no clarity regarding the road map for future research. Therefore, formulations such as concepts, theories, methods, and research gaps, focusing on interest-free financing in agro-industry, are essential. This literature study was conducted using a systematic literature review method. The data used are secondary data from textbooks, theses/dissertations, conference papers, journals, scientific articles, and working papers. This study resulted in the formulation of the theory, concepts, and methods studied in the form of an explanation of 8 sub-topics of research gaps supported by references and explanations of state of the art. They are making it easier for researchers who have the same interest in developing and looking for novelties with the topic of interest-free financing research in the agro-industry.

scholarly journals The Big Why of Implementing Computational Thinking In STEM Education: A Systematic Literature Review

2021 ◽  
Vol 6 (3) ◽  
pp. 272-289
Author(s):  
Norhafizan Abdul Wahab ◽  
Othman Talib ◽  
Fazilah Razali ◽  
Nurzatulshima Kamarudin
Keyword(s):  
Literature Review ◽  
Stem Education ◽  
Systematic Literature Review ◽  
Web Of Science ◽  
Meta Analysis ◽  
Computational Thinking ◽  
Considerable Effect ◽  
Research Gaps ◽  
Prisma Statement

Computational Thinking (CT) has been increasingly embraced as a reformation in STEM education. This paper discusses why the implementation of CT would have a considerable effect on STEM education. The first objective of this systematic literature review is to identify the subjects that incorporate the most elements of CT in STEM education. Secondly, it aims to provide an overview of CT practices in the classrooms. Finally, the major findings of this study seek to discuss the benefits and challenges of the use of CT in STEM education. Fifteen articles were methodically selected from Scopus, Web of Science, Dimensions, and Google Scholar databases as the relevant studies to be discussed in this systematic study, based on the PRISMA Statement (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) review technique. This review identifies current research gaps and directions for the practice and implementation of CT in STEM education. Further analysis of the articles has contributed to a conclusion that CT has become more widespread and multi-disciplinary and seems to have propagated improvements in STEM education. Still, a new study is required, especially on long-term implications.

scholarly journals Commercialization of conventional and sustainability-oriented innovations: a comparative systematic literature review

2021 ◽  
Vol 19 (1) ◽  
pp. 340-353
Author(s):  
Dinara Kalmakova ◽  
Yuriy Bilan ◽  
Aknur Zhidebekkyzy ◽  
Rimma Sagiyeva
Keyword(s):  
Economic Growth ◽  
Literature Review ◽  
Systematic Literature Review ◽  
Scientific Debate ◽  
Innovation Research ◽  
Comparative Review ◽  
Strategic Factors ◽  
Impact Of Technology ◽  
The Impact

Innovations play an important role in achieving competitiveness and long-term economic growth at all levels of the economic hierarchy. More recently, the role of sustainability-oriented innovation in achieving economic growth has become equally important. However, there is a scientific debate about the possibility of effective commercialization of sustainability-oriented innovations. The existence of such scientific debate, as well as the absence of citation-based systematic literature reviews, became a prerequisite for conducting a comparative literature review of research on the effective commercialization of conventional and sustainability-oriented innovations. The purpose of the study is to conduct a comparative review and analysis of research on the commercialization efficiency of conventional and sustainability-oriented innovations. The analysis was conducted on the basis of a citation-based systematic literature review method. The results show that sustainable innovation research is more focused on the relationship between commercialization and firm performance. In the field of conventional innovations, research trends have shifted from studying the impact of technology transfer office (TTO) size, staffing, compensation practices to how strategic factors affect the efficiency of commercialization. In the area of sustainability-oriented innovation, the issues of the strategic orientation impact cause the most sustained interest, while managerial concerns and the stringency of environmental regulations have been actively explored in the past few years. It was revealed that the commercialization efficiency of sustainability-oriented innovations is characterized by so called sustainability-oriented criteria. A distinctive output criterion for commercialization efficiency of sustainability-oriented innovation is the improvement of the firm’s image. In addition, content analysis identified possible research directions to be investigated.

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