scholarly journals TL 18176 - Platelet-rich plasma versus corticosteroid injection in pain and disability outcomes in patients with plantar fasciitis

2019 ◽  
Vol 13 (Supl 1) ◽  
pp. 102S
Author(s):  
Janice De Souza Guimarães ◽  
Fabio Luciano Arcanjo de Jesus ◽  
Gustavo Leporace De Oliveira Lomelino So ◽  
Leonardo Fossati Metsavaht ◽  
Marcus Vinicius Mota Garcia Moreno ◽  
...  

Introduction: Fascite Plantar é a causa mais comum de dor no calcanhar e muitas vezes responde a uma ampla gama de terapias. Atualmente existem muitas opções de tratamento, sendo que algumas, como plasma rico em plaquetas e injeção de corticosteroides, apresentam grande sucesso no alívio da dor. Entretanto, não há consenso sobre o melhor método de tratamento. O objetivo desta revisão sistemática e meta-análise foi investigar os efeitos do plasma rico em plaquetas versus injeção de corticosteróides em desfechos de dor e incapacidade no paciente com fascite plantar.  Métodos: Os estudos foram amplamente pesquisados ​​em PubmedMEDLINE, na base de dados PEDro, na biblioteca eletrônica científica online (SciELO) e no registro central de ensaios controlados da Cochrane, desde a data mais antiga disponível até janeiro de 2019. Foram incluídos ensaios clínicos controlados randomizados que compararam os efeitos do plasma rico em plaquetas versus injeção de corticosteróides para paciente com fascite plantar. Foram calculados as diferenças médias (DM) e intervalos de confiança (ICs) de 95%, e a heterogeneidade foi avaliada usando o teste I2. Os cálculos foram feitos usando um modelo de efeito aleatório.  Resultados: Dez artigos preencheram os critérios do estudo, incluindo 475 pacientes com fascite plantar. Os principais resultados incluíram alterações da linha de base no Escore da Escala Visual Analógica (dor) e no Escore da Sociedade Ortopédica Americana do Pé e Tornozelo (incapacidade). A terapia com plasma rico em plaquetas resultou em melhora na dor (DM -1,01 IC95%: -1,8 a -0,3, N=375) em comparação com a injeção de corticosteróides. Não foi encontrada nenhuma diferença significativa na incapacidade (DM 6,5 IC95%: -15,8 a 29,0, N=156) em participantes do grupo de terapia com plasma rico em plaquetas em comparação com o grupo de injeção de corticosteróides. Além disso, nenhum evento adverso grave foi relatado.  Conclusão: O plasma rico em plaquetas foi mais eficaz do que a injeção de corticosteróides e tem o potencial de reduzir a dor do paciente com fascite plantar.

Author(s):  
Harpreet Singh ◽  
Malay P. Gandhi ◽  
Aliasgar J. Rampurwala ◽  
Tej S. Rudani

<p class="abstract"><strong>Background:</strong> Plantar fasciitis (PF) is considered as degenerative tendinopathies. Repeated micro trauma is the major etiology of these diseases. Autologous platelet rich plasma (PRP) injections are becoming more popular in the treatment of enthesopathies like PF. The growth factors in PRP cause tissue healing. We compared the result of injecting intra-lesional autologous PRP injections versus steroid infiltration in chronic PF.</p><p class="abstract"><strong>Methods:</strong> A prospective, interventional and analytic comparative study was done and 81 patients (120 heels) were included in this study and were followed up for 6 months. We assessed the outcome of each patient using visual analog score (VAS) and foot and ankle disability index (FADI) on follow-up at 1, 3, and 6 months. <strong></strong></p><p class="abstract"><strong>Results:</strong> In our study, female preponderance was seen. Left side was more common as compared to right side. Unilateral PF is more common than bilateral. The difference with in the individual group at baseline and at 1,3 and 6 months was statistically highly significant in terms of VAS and FADI (p=0.0001) But the difference in the between the two groups was insignificant for VAS and FADI at 1, 3 and 6 months.</p><p class="abstract"><strong>Conclusions:</strong> In our study, as there is no significant difference in VAS and FADI score between corticosteroid injection group and PRP injection group at 1, 3 and 6 months follow up. So, it’s reasonable to conclude that both are equally effective in PF. But as PRP injection comes out to be more time consuming and more costly, corticosteroid seems to be more efficient, cost and time wise. Hence, the latter should be a better choice.      </p>


Author(s):  
Vithal Prakash Puri ◽  
Anil Kumar Gaur

<p class="abstract"><strong>Background:</strong> The heel pain is the most common problem worldwide and it was associated with plantar fasciitis (PF). The condition of treatment is very complex. Platelet-rich plasma (PRP) and injection of corticosteroids is the treatment of PF. This study was designed to access the effect of local PRP and local corticosteroid injection in PF patients.</p><p class="abstract"><strong>Methods:</strong> Sixty patients (between 29 to 60 years of age) with chronic PF were randomized prospectively in single tertiary care center in India. The study conducted from December 2013 to December 2015. All the patients were enrolled according to inclusion criteria and divided into two groups randomized. In group A (n=30) received PRP and group B (n=30) received corticosteroids injections. Visual analog scales (VAS) were filled by all the included patients. The follow-up scheduled at one and six months after complete enrolment of patients.<strong></strong></p><p class="abstract"><strong>Results:</strong> Between both the groups the significantly different observed at one and six months follow-up from the baseline. At one month follow-up significantly improvement in mean VAS score were observed in group B (p&lt;0.001). At six months follow-up significantly improvement in mean VAS score were observed in group A (p&lt;0.001).</p><p class="abstract"><strong>Conclusions:</strong> The present study concluded from the significance difference between both the groups proved promising form of treatment in chronic PF patients. Both the treatment was safe and effective in relieving pain improving function at different time period.</p><p> </p>


2016 ◽  
Vol 25 (2) ◽  
pp. 202-207 ◽  
Author(s):  
Shanna L. Karls ◽  
Kelli R. Snyder ◽  
Peter J. Neibert

Clinical Scenario:For active individuals, plantar fasciitis (PF) is one of the most clinically diagnosed causes of heel pain. When conservative treatment fails, one of the next most commonly used treatments includes corticosteroid injections. Although PF has been identified as a degenerative condition, rather than inflammatory, corticosteroid injection is still commonly prescribed. However, the literature has not been examined to determine the effect of corticosteroid injection on PF.Focused Clinical Question:Are corticosteroid injections more effective than other interventions (placebo, platelet-rich plasma, and tenoxicam injections) in the short- and long-term treatment of PF?Summary of Key Findings:Corticosteroid injections are not more effective in the long-term treatment of PF pain than other treatments (platelet-rich plasma, tenoxicam).Clinical Bottom Line:The level 2 and 3 evidence shows that corticosteroids are more effective than placebo injections but are no more effective than tenoxicam injections and perhaps less effective than platelet-rich plasma treatment.Strength of Recommendation:Level 2 and 3 evidence suggests that corticosteroid injections are not more effective in the long-term treatment of PF than platelet-rich plasma or tenoxicam.


2019 ◽  
Vol 47 (13) ◽  
pp. 3238-3246 ◽  
Author(s):  
Joost C. Peerbooms ◽  
Paul Lodder ◽  
Brenda L. den Oudsten ◽  
Kamiel Doorgeest ◽  
Hans M. Schuller ◽  
...  

Background: When nonoperative treatment for chronic plantar fasciitis fails, often a corticosteroid injection is given. Corticosteroid injection gives temporary pain reduction but no healing. Platelet-rich plasma (PRP) has proven to be a safe therapeutic option in the treatment of tendon, muscle, bone, and cartilage injuries. Purpose: To determine the effectiveness of PRP as compared with corticosteroid injections for chronic plantar fasciitis. Study Design: Randomized controlled trial; Level of evidence, 1. Methods: Patients with chronic plantar fasciitis were allocated to have steroid injection or PRP. The primary outcome measure was the Foot Function Index (FFI) Pain score. Secondary outcome measures were function, as scored by the FFI Activity, FFI Disability, and American Orthopaedic Foot & Ankle Society, and quality of life, as scored with the short version of the World Health Organization Quality of Life (WHOQOL-BREF). All outcomes were measured at baseline and at 4, 12, and 26 weeks and 1 year after the procedure. Results: Of the 115 patients, 63 were allocated to the PRP group, of which 46 (73%) completed the study, and 52 were allocated to the control group (corticosteroid injection), of which 36 (69%) completed the study. In the control group, FFI Pain scores decreased quickly and then remained stable during follow-up. In the PRP group, FFI Pain reduction was more modest but reached a lower point after 12 months than the control group. After adjusting for baseline differences, the PRP group showed significantly lower pain scores at the 1-year follow-up than the control group (mean difference, 14.4; 95% CI, 3.2-25.6). The number of patients with at least 25% improvement (FFI Pain score) between baseline and 12-month follow-up differed significantly between the groups. Of the 46 patients in the PRP group, 39 (84.4%) improved at least 25%, while only 20 (55.6%) of the 36 in the control group showed such an improvement ( P = .003). The PRP group showed significantly lower FFI Disability scores than the control group (mean difference, 12.0; 95% CI, 2.3-21.6). Conclusion: Treatment of patients with chronic plantar fasciitis with PRP seems to reduce pain and increase function more as compared with the effect of corticosteroid injection. Registration: NCT00758641 (ClinicalTrials.gov identifier).


The Foot ◽  
2015 ◽  
Vol 25 (4) ◽  
pp. 235-237 ◽  
Author(s):  
Kowshik Jain ◽  
Philip N. Murphy ◽  
Timothy M. Clough

2017 ◽  
Vol 4 (2) ◽  
pp. 84-89
Author(s):  
Gyaneshwar Tank ◽  
Ravikant Rohila ◽  
Rohit Gupta, ◽  
Amit Gupta,

ABSTRACT Introduction Platelet-rich plasma (PRP) is promoted now­adays as an ideal autologous biological blood-derived product. It enhances wound healing, bone healing, tendon healing and is currently being widely used. Aims and objectives A prospective cohort study was done to assess the efficacy of autologous PRP injection and to compare it with corticosteroid injection in treatment of plantar fasciitis (PF). Materials and methods Eighty patients were included in the study and divided into two groups. Group I (30 patients) received PRP injection and group II (50 patients) were given steroid injection. Patients were clinically assessed at different intervals. Functional outcome was evaluated on the basis of visual analog scale (VAS) and foot and ankle ability measure (FAAM) scores. Planter fascia thickness was assessed pre- and postinjection by ultrasound. Results Platelet-rich plasma and corticosteroid injection groups at the initial visit had VAS score of 8.44 and 8.38 respectively which was reduced to 1.46 and 3.02 at the end of 6 months. The PRP and corticosteroid injection groups at the initial visit had FAAM score of 29.9 and 31.6 respectively which increased to 83.4 and 69.1 at the end of 6 months. After injection, the PRP group had significant reduction (35.90%) in the thickness of plantar fascia as compared to corticosteroid group (28.67%). Conclusion Treatment of PF with PRP extract reduces pain and significantly increases function, exceeding the effect of steroid on long-term follow-up. How to cite this article Tank G, Gupta R, Gupta A, Rohila R. Comparative Study of Platelet-rich Plasma and Corticosteroid Injection in the Treatment of Plantar Fasciitis. J Foot Ankle Surg (Asia-Pacific) 2017;4(2):84-89.


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