Degenerate Primer Based PCR for Rapid and Accurate Detection of Infectious Pathogens, Acinetobacter baumannii, and Staphylococcus aureus, with the Targeting of FtsZ Gene

2020 ◽  
Vol 35 (3) ◽  
pp. 174-179
Author(s):  
M. Moosazadeh Moghaddam ◽  
H. Zare ◽  
H. Tebyanian ◽  
A. Hakakian ◽  
M. Heiat ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Acinetobacter Baumannii ◽  
Degenerate Primer ◽  
Accurate Detection ◽  
Ftsz Gene ◽  
And Staphylococcus Aureus

scholarly journals A Study on Acinetobacter baumannii and Staphylococcus aureus Strains Recovered from the Same Infection Site of a Diabetic Patient

2019 ◽  
Vol 76 (7) ◽  
pp. 842-847 ◽  
Author(s):  
Nancy Castellanos ◽  
Jun Nakanouchi ◽  
Dennis Irfan Yüzen ◽  
Sammie Fung ◽  
Jennifer S. Fernandez ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Diabetic Patient ◽  
Acinetobacter Baumannii ◽  
Infection Site ◽  
And Staphylococcus Aureus

scholarly journals Structure-Activity Relationship Modeling and Experimental Validation of the Imidazolium and Pyridinium Based Ionic Liquids as Potential Antibacterials of MDR Acinetobacter Baumannii and Staphylococcus Aureus

2021 ◽  
Vol 22 (2) ◽  
pp. 563
Author(s):  
Ivan V. Semenyuta ◽  
Maria M. Trush ◽  
Vasyl V. Kovalishyn ◽  
Sergiy P. Rogalsky ◽  
Diana M. Hodyna ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Ionic Liquids ◽  
Acinetobacter Baumannii ◽  
Predictive Accuracy ◽  
Coefficient Of Determination ◽  
Chemical Library ◽  
Chemical Modeling ◽  
Qsar Analysis ◽  
Test Sets ◽  
And Staphylococcus Aureus

Online Chemical Modeling Environment (OCHEM) was used for QSAR analysis of a set of ionic liquids (ILs) tested against multi-drug resistant (MDR) clinical isolate Acinetobacter baumannii and Staphylococcus aureus strains. The predictive accuracy of regression models has coefficient of determination q2 = 0.66 − 0.79 with cross-validation and independent test sets. The models were used to screen a virtual chemical library of ILs, which was designed with targeted activity against MDR Acinetobacter baumannii and Staphylococcus aureus strains. Seven most promising ILs were selected, synthesized, and tested. Three ILs showed high activity against both these MDR clinical isolates.

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