The Biological Activity of Eucalyptus rostrata Leaves Extraction against E.coli and Staphylococcus aureus isolated from Iraqi Patients

2018 ◽  
Vol 59 (4A) ◽  
Keyword(s):  
Staphylococcus Aureus ◽  
Biological Activity ◽  
And Staphylococcus Aureus

Development of phyllanthin containing microcapsules and their improved biological activity towards skin cells and Staphylococcus aureus

2012 ◽  
Vol 22 (1) ◽  
pp. 468-471 ◽  
Author(s):  
Pik-Ling Lam ◽  
Roberto Gambari ◽  
Joanne Yip ◽  
Marcus Chun-Wah Yuen ◽  
Kim-Hung Lam ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Biological Activity ◽  
Skin Cells ◽  
And Staphylococcus Aureus

scholarly journals New 3- hydrazonoindolin-2-one Cd(II) complexes with amino pyridine ligands, Synthesis, Characterization and biological activity evaluation

2020 ◽  
Vol 25 (2) ◽  
pp. 38
Author(s):  
Lubna W. Mohammed ◽  
Ahmed A. Irzoqi
Keyword(s):  
Staphylococcus Aureus ◽  
Biological Activity ◽  
Staphylococcus Epidermidis ◽  
Heterocyclic Ring ◽  
Azomethine Group ◽  
Gram Positive Bacteria ◽  
Pyridine Ligands ◽  
Tetrahedral Complexes ◽  
And Staphylococcus Aureus

This research includes synthesis and characterization of some of Cd(II) complexes with (3-hydrazonoindolin-2-one)(HZI) ligand and amino pyridine ligands.    Treatment equialmolar of CdCl2.2.5H2O and (HZI) ligand with two moles of n-aminopyridine (n-amp) (n:2,3,4) ligands afford a tetrahedral complexes of the type [Cd(HZI)(n-amp)2]Cl2, where (HZI) ligand behaves as a bidentate chelating fashion through the N atom of azomethine group and  O atom of carbonyl group. Whereas the (n-amp)(n: 2,3,4) was bonded monodentate mode through the N atom of heterocyclic ring. The prepared complexes have been characterized by molar conductivity, elemental analysis, infrared spectra and 1H-NMR and 13C-NMR spectra. Also the evaluation of biological activity of the prepared complexes against two types of gram positive bacteria (Staphylococcus Epidermidis and Staphylococcus aureus) and (Citrobacer Freundii) and gram negative, all prepared complexes showed activity against Staphylococcus aureus more than  amikacin, while the [Cd(HZI)(3-amp)2]Cl2 complex showed high activity against Staphylococcus Epidermidis and Citrobacter freundii more than another prepared complexes   http://dx.doi.org/10.25130/tjps.25.2020.028

scholarly journals Synthesis , Characterization and Study of Biological Activity of Some New Schiff Bases ,1,3-Oxazepine and Tetrazole Derived from 2,2 di thiophenyl Acetic Acid

2018 ◽  
Vol 31 (1) ◽  
pp. 189 ◽  
Author(s):  
Eman M. Hussain ◽  
Hussam Z. Naji
Keyword(s):  
Mass Spectrometry ◽  
Staphylococcus Aureus ◽  
Acetic Acid ◽  
Biological Activity ◽  
Hydrazine Hydrate ◽  
Schiff Bases ◽  
Sodium Azide ◽  
Derivatives Of ◽  
Tetrazole Derivatives ◽  
And Staphylococcus Aureus

         In this study  new  derivatives  of  Schiff bases 5-8 , 1,3- oxazepine  9-16 and tetrazoles 17-19 have  been synthesized from the new starting  material 1 which has  synthesized  the reaction of  one mole of dichloro acetic acid and two moles of  thiophenol , the esters  2-3 were synthesized from the reaction of  compound 1 with methanol or ethanol respectively  in the presence of  H2SO4  as  catalyst  then 2,2-dithiophenylaceto Hydrazide  4 were synthesized from the reaction of  2 or 3 with hydrazine hydrate  80 % , Schiff bases 5-8 were  synthesized from the reaction of  4 with appropriate aldehyde or ketone .Treatment  of  Schiff bases with maleic and phathalic  anhydride in dry benzene to give 1,3-oxazepen derivatives  9-16 and with sodium azide in tetrahydrofuran (THF) afforded  tetrazole derivatives 17-19. All these compounds have been characterized from their melting pointes, FTIR , 1HNMR and compounds 1,5 and 18 by mass spectrometry . Derivatives 6,7,11,16,17 and 18 were tested against inhibition of E.coli and. Staphylococcus- aureus and were all funds to be active. Scheme (1).

scholarly journals The compounds and biological activity of Thamnosma africana

2006 ◽  
Vol 25 (3) ◽  
Author(s):  
H. F. Mafokane ◽  
N. Potgieter ◽  
T. Van Ree
Keyword(s):  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Plasmodium Falciparum ◽  
Biological Activity ◽  
Ethyl Acetate Extract ◽  
Chemical Compounds ◽  
Volatile Oil ◽  
E Coli ◽  
Aerial Parts ◽  
And Staphylococcus Aureus

The aerial parts and fruits of Thamnosma africana were investigated for chemical compounds present in them. The volatile oil of T. africana was prepared by hydrodistillation of leaves, flowers and stems, and characterized by GC-MS. The oil was tested for antimicrobial activity on cultures of E. coli, B. subtilis and S.aureus, and found to inhibit Bacillus subtilis and Staphylococcus aureus at 0.1% dilution. The oil was also active against Plasmodium falciparum in micromolar concentrations. Chromatographic separation of the ethyl acetate extract of the aerial parts yielded two isomers of methoxypsoralen (xanthotoxin and bergapten) and 6-(1c,2c-dihydroxy-3c-methyl-3c-butenyl)-7-methoxychromen-2-one (thamnosmonin). The epoxide of thamnosmonin, 6-(1c,2c-epoxy-3c-methylbut-3c-en-1c-yl)-7-methoxychromen-2-one (thamnosmin), and methyl p-isopentenyloxycinnamate were isolated from the hexane extract of the fruits, while another furanocoumarin, 4,9-dimethoxy-7H-furo[3,2-g]benzopyran-7-one (isopimpinellin) was isolated from a dichloromethane extract of the aerial parts.

Synthesis of Some New Derivatives of Pyrrolidine-2-one and Studying Their Antibacterial Potentials

2020 ◽  
Vol 38 (3B) ◽  
pp. 128-141
Author(s):  
Nadia A. Betti ◽  
Redha Ib. Hussain ◽  
Sahar Ab. Kadhem
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Biological Activity ◽  
Hydrazine Hydrate ◽  
1H Nmr ◽  
Mass Spectra ◽  
Biological Activities ◽  
Ft Ir ◽  
Derivatives Of ◽  
And Staphylococcus Aureus

New derivatives of pyrrolidine-2-one have been synthesized through lactamization of γ –butyrolactone (GBL) by hydrazine hydrate (80%), ethylene diamine and ethanol amine to afford compounds (1-aminopyrrolidin-2-one), (1-(2-aminoethyl)pyrrolidine-2-one) and (1-(2-hydroxyethyl)pyrrolidine-2-one), respectively. Compound (1-aminopyrrolidin-2-one) underwent several reactions to synthesize the rest of these derivatives. All synthesized compounds were approved by their FT-IR, 1H-NMR and some by Mass spectra. The biological activities of these derivatives were evaluated against Escherichia coli and Staphylococcus aureus. Many of these derivatives showed moderate biological activity against one or both kind of bacteria in comparison to amoxicillin and some showed no biological activity at all.

A Convenient Synthesis of new Phenanthrolinone and Naphthyridinone Derivatives: Evaluation of their Biological activity

2014 ◽  
Vol 9 (1) ◽  
pp. 1866-1872
Author(s):  
Mona A. Hosny ◽  
Wafaa A. Mokbel ◽  
Emtithal A. El-Sawi
Keyword(s):  
Staphylococcus Aureus ◽  
Biological Activity ◽  
Candida Albicans ◽  
Sodium Hydroxide ◽  
Good Activity ◽  
Substituted Phenols ◽  
Smiles Rearrangement ◽  
Convenient Synthesis ◽  
Effective Synthesis ◽  
And Staphylococcus Aureus

A novel and effective synthesis of substituted acetamide via smiles rearrangement is described. Treatment of phenols with 2-chloroacetamide in the presence of sodium hydroxide and DMA where substituted phenols, which contain electron withdrawing groups, are more reactive for smiles rearrangement. The reaction followed by cyclization of the product by E.A.A. afforded the corresponding substituted phenanthrolinone and naphthyridinone in good yields and showed higher activity against (G- and G+, Eschierchia coli and Staphylococcus aureus respectively) and good activity toward Aspergillius flavus and Candida albicans.

scholarly journals A Convenient Synthesis of new Phenanthrolinone and Naphthyridinone Derivatives: Evaluation of their Biological activity

2013 ◽  
Vol 9 (1) ◽  
pp. 1866-1872
Author(s):  
Mona A. Hosny ◽  
Wafaa A. Mokbel ◽  
Emtithal A. El-Sawi
Keyword(s):  
Staphylococcus Aureus ◽  
Biological Activity ◽  
Candida Albicans ◽  
Sodium Hydroxide ◽  
Good Activity ◽  
Substituted Phenols ◽  
Smiles Rearrangement ◽  
Convenient Synthesis ◽  
Effective Synthesis ◽  
And Staphylococcus Aureus

A novel and effective synthesis of substituted acetamide via smiles rearrangement is described. Treatment of phenols with 2-chloroacetamide in the presence of sodium hydroxide and DMA where substituted phenols, which contain electron withdrawing groups, are more reactive for smiles rearrangement. The reaction followed by cyclization of the product by E.A.A. afforded the corresponding substituted phenanthrolinone and naphthyridinone in good yields and showed higher activity against (G- and G+, Eschierchia coli and Staphylococcus aureus respectively) and good activity toward Aspergillius flavus and Candida albicans.

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