scholarly journals A Comparative Study of Iron Oxide Nanoparticles Surface Modified Using Carboxylic Acids

2021 ◽  
Vol 8 (1) ◽  
pp. 116-125
Author(s):  
Archana S.
Keyword(s):  
Surface Modification ◽  
Iron Oxide ◽  
Magnetic Nanoparticles ◽  
Comparative Study ◽  
Succinic Acid ◽  
Iron Oxide Nanoparticles ◽  
The Body ◽  
Precipitation Method ◽  
Iron Oxide Nanoparticle ◽  
Oxide Nanoparticles

In the last decade nanotechnology has greatly developed in many research fields such as engineering, electronic, biological and many others. They can offer several possibilities to design tools, to create new techniques or improve the already existing ones, to discover innovative applications. Nano-science is one of the most important research and development frontiers in modern science. Nanotechnology is now widely used throughout the pharmaceutical industry, medicine, electronics, robotics, and tissue engineering. For biological and biomedical applications, magnetic iron oxide nanoparticles are the primary choice because of their biocompatibility, super-paramagnetic behavior and chemical stability. The purpose of this work is the design, development and surface modification of magnetic nanoparticles. Naked iron oxide nanoparticles have high chemical activity, toxicity and aggregate in the body fluid therefore providing surface coating for the stability of the magnetic nanoparticles. These protective shells not only stabilize the magnetic iron nanoparticles but also can be used for further functionalization. Here the iron oxide nanoparticles were prepared by co-precipitation method, then this nanoparticle is modified using acids- oleic acid and succinic acid and a comparative study is carried out. The TEM, FTIR and DSC characterization techniques were used to confirm the surface modification. After which, it was found the iron oxide nanoparticle with succinic acid gives a uniform coating of the three and can be used for further functionalization for various applications.

Investigation of Magnetic Iron Oxide Nanoparticle Properties with Co-Precipitation Methods under Different Reaction Conditions

2020 ◽  
Vol 10 ◽  
Author(s):  
Sema Salgın ◽  
Uğur Salgın ◽  
Nagihan Soyer
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Morphological Structure ◽  
Precipitation Method ◽  
Iron Oxide Nanoparticle ◽  
Hydrodynamic Diameter ◽  
Oxide Nanoparticles ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Magnetic Iron Oxide ◽  
Co Precipitation

: In this study, magnetic iron oxide nanoparticles were synthesized by cost effective and an easy co-precipitation method. The effects of reaction parameters such as the mole ratio of Fe2+/Fe3+ (1/1, 1/2 and 1/3) and the base type (NaOH and NH4OH) on the average hydrodynamic diameter, zeta potential, chemical and morphological structure and saturation magnetization values of magnetic iron oxide nanoparticles were systematically investigated. Magnetic iron oxide nanoparticles synthesized at the mole ratio of 1/2 using NH4OH base gave better results in terms of particle size and particle shape, magnetization value. In order to prevent the formation of different phases in the co-precipitation method, an alternative approach was developed and the reaction was performed using inert supercritical CO2 atmosphere.

Evaluation of Surface-modified Superparamagnetic Iron Oxide Nanoparticles to Optimize Bacterial Immobilization for Bio-separation with the Least Inhibitory Effect on Microorganism Activity

2020 ◽  
Vol 10 (2) ◽  
pp. 166-174
Author(s):  
Mehdi Khoshneviszadeh ◽  
Sarah Zargarnezhad ◽  
Younes Ghasemi ◽  
Ahmad Gholami
Keyword(s):  
Iron Oxide ◽  
Amino Acid ◽  
Magnetic Nanoparticles ◽  
Iron Oxide Nanoparticles ◽  
Surface Coating ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Surface Charges ◽  
Surface Modified

Background: Magnetic cell immobilization has been introduced as a novel, facile and highly efficient approach for cell separation. A stable attachment between bacterial cell wall with superparamagnetic iron oxide nanoparticles (SPIONs) would enable the microorganisms to be affected by an outer magnetic field. At high concentrations, SPIONs produce reactive oxygen species in cytoplasm, which induce apoptosis or necrosis in microorganisms. Choosing a proper surface coating could cover the defects and increase the efficiency. Methods: In this study, asparagine, APTES, lipo-amino acid and PEG surface modified SPIONs was synthesized by co-precipitation method and characterized by FTIR, TEM, VSM, XRD, DLS techniques. Then, their protective effects against four Gram-positive and Gram-negative bacterial strains including Enterococcus faecalis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa were examined through microdilution broth and compared to naked SPION. Results: The evaluation of characterization results showed that functionalization of magnetic nanoparticles could change their MS value, size and surface charges. Also, the microbial analysis revealed that lipo-amino acid coated magnetic nanoparticles has the least adverse effect on microbial strain among tested SPIONs. Conclusion: This study showed lipo-amino acid could be considered as the most protective and even promotive surface coating, which is explained by its optimizing effect on cell penetration and negligible reductive effects on magnetic properties of SPIONs. lipo-amino acid coated magnetic nanoparticles could be used in microbial biotechnology and industrial microbiology.

Preparation of magnetized iron oxide grafted on graphene oxide for hyperthermia application

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Ahmad Abulfathi Umar ◽  
Muhamad Fazly Abdul Patah ◽  
Faisal Abnisa ◽  
Wan Mohd Ashri Wan Daud
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Near Infrared ◽  
Malignant Tumors ◽  
Synthesis Method ◽  
Therapeutic Modality ◽  
Iron Oxide Nanoparticle ◽  
Oxide Nanoparticles ◽  
Hybrid Nanostructure ◽  
Characterization Techniques

AbstractMagnetic hyperthermia therapy (MHT) is a highly promising therapeutic modality for the treatment of different kinds of cancers and malignant tumors. The therapy is based on the concept that; iron oxide nanoparticles deposited at cancer sites can generate heat when exposed to an alternating current magnetic field or near infrared radiation and consequently destroying only the cancer cells by exploiting their vulnerability to heat. The fact that the treatment is at molecular level and that iron oxide nanoparticles provide more guided focus heating justifies its efficacy over treatment such as surgery, radiation therapy and chemotherapy. Nevertheless, the spread of MHT as the next-generation therapeutics has been shadowed by insufficient heating especially at the in vivo stage. This can be averted by modifying the iron oxide nanoparticle structure. To this end, various attempts have been made by developing a magnetic hybrid nanostructure capable of generating efficient heat. However, the synthesis method for each component (of the magnetic hybrid nanostructure) and the grafting process is now an issue. This has a direct effect on the performance of the magnetic hybrid nanostructure in MHT and other applications. The main objective of this review is to detail out the different materials, methods and characterization techniques that have been used so far in developing magnetic hybrid nanostructure. In view of this, we conducted a comprehensive review and present a road map for developing a magnetic hybrid nanostructure that is capable of generating optimum heat during MHT. We further summarize the various characterization techniques and necessary parameters to study in validating the efficiency of the magnetic hybrid nanostructure. Hopefully, this contribution will serve as a guide to researchers that are willing to evaluate the properties of their magnetic hybrid nanostructure.

Succinylated heparin monolayer coating vastly increases superparamagnetic iron oxide nanoparticle T2 proton relaxivity

Nanoscale ◽  
2019 ◽  
Vol 11 (27) ◽  
pp. 12905-12914 ◽  
Author(s):  
Manman Xie ◽  
Shijia Liu ◽  
Christopher J. Butch ◽  
Shaowei Liu ◽  
Ziyang Wang ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Contrast Agents ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Iron Oxide Nanoparticle ◽  
Oxide Nanoparticles ◽  
Clinical Use ◽  
History Of ◽  
Oxide Nanoparticle ◽  
Superparamagnetic Iron Oxide Nanoparticle

Superparamagnetic iron oxide nanoparticles (SPIONs) have a history of clinical use as contrast agents in T2 weighted MRI, though relatively low T2 relaxivity has caused them to fall out of favor as new faster MRI techniques have gained prominence.

Comparative study on the magnetic properties of iron oxide nanoparticles loaded on mesoporous silica and carbon materials with different structure

2009 ◽  
Vol 121 (1-3) ◽  
pp. 178-184 ◽  
Author(s):  
Sher Alam ◽  
Chokkalingam Anand ◽  
Radhakrishnan Logudurai ◽  
Veerappan V. Balasubramanian ◽  
Katsuhiko Ariga ◽  
...  
Keyword(s):  
Magnetic Properties ◽  
Iron Oxide ◽  
Mesoporous Silica ◽  
Comparative Study ◽  
Iron Oxide Nanoparticles ◽  
Carbon Materials ◽  
Oxide Nanoparticles

Effect of aluminum doped iron oxide nanoparticles on magnetic properties of the polyacrylonitrile nanofibers

2017 ◽  
Vol 37 (2) ◽  
pp. 135-141
Author(s):  
Armin Ourang ◽  
Soheil Pilehvar ◽  
Mehrzad Mortezaei ◽  
Roya Damircheli
Keyword(s):  
Magnetic Properties ◽  
Iron Oxide ◽  
Magnetic Nanoparticles ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Negative Interaction ◽  
Magnetic Nanofibers

Abstract In this work, polyacrylonitrile (PAN) was electrospun with and without magnetic nanoparticles (aluminum doped iron oxide) and was turned into magnetic nanofibers. The results showed that nanofibers diameter decreased from 700 nm to 300 nm by adding nanoparticles. Furthermore, pure PAN nanofibers were indicated to have low magnetic ability due to polar bonds that exist in their acrylonitrile groups. Obviously by adding only 4 wt% of the nanoparticles to PAN nanofibers, magnetic ability soared by more than 10 times, but at a higher percentage, it was shown to change just a little due to negative interaction among nanoparticles. This event relates to antiferromagnetically coupling of nanoparticles due to incomplete dispersion at higher percentage.

One pot synthesis and surface modification of mesoporous iron oxide nanoparticles

2019 ◽  
Vol 19 ◽  
pp. 100343 ◽  
Author(s):  
Ruby Phul ◽  
Vipul Shrivastava ◽  
Umar Farooq ◽  
Meryam Sardar ◽  
Abul Kalam ◽  
...  
Keyword(s):  
Surface Modification ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
One Pot ◽  
One Pot Synthesis

The Effect of Focused Ultrasound on Magnetic Polyelectrolyte Capsules Loaded with Dye When Suspended in Tissue-Mimicking Gel

2019 ◽  
Vol 16 (4) ◽  
pp. 355-363 ◽  
Author(s):  
Carmen Stavarache ◽  
Mircea Vinatoru ◽  
Timothy Mason
Keyword(s):  
Iron Oxide ◽  
Magnetic Nanoparticles ◽  
Iron Oxide Nanoparticles ◽  
Exposure Time ◽  
Ultrasonic Irradiation ◽  
Focused Ultrasound ◽  
Relative Degree ◽  
Oxide Nanoparticles ◽  
Dye Release ◽  
Iron Oxide Magnetic Nanoparticles

Background: Capsules containing a dye were prepared by the LbL method with iron oxide nanoparticles (50 nm) in different layers of the shell. Method: The capsules were dispersed in a gel and subjected to focused ultrasonic irradiation at three different powers and exposure times. Result: It was found that the inclusion of iron oxide magnetic nanoparticles in any of the polyelectrolyte shells (4, 6, 8 and 10) strengthened the capsules with respect to capsules without nanoparticles. Incorporation of nanoparticles in shell 8 provided the most resistance to fragmentation under focused ultrasonic irradiation. The relative degree of capsule stability is dependent on both the power of the ultrasound and the exposure time. Conclusion: The presence of iron oxide nanoparticles not only conferred more resistance to fragmentation but also provided a route to protein labelled dye release through sonoporation that was not present for capsules without nanoparticles.

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