Prognostic criteria of psychophysiological adaptation according to visual and computer EEG analyses of employees of nuclear hazardous enterprises and industries

2021 ◽  
Vol 61 (9) ◽  
pp. 588-593
Author(s):  
Zoya F. Zvereva ◽  
Felix S. Torubarov ◽  
Svetlana N. Lukyanova ◽  
Elena A. Denisova ◽  
Elena V. Miroshnik
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Cardiovascular System ◽  
Visual Analysis ◽  
Spectral Power ◽  
Central Regulation ◽  
Low Level ◽  
Prognostic Criteria ◽  
The Central Nervous System ◽  
Different Levels

Introduction. The study's relevance is due to the need to improve the safety of nuclear industry enterprises and, as a consequence, to ensure a good level of psychophysiological functioning of employees. The study aims to identify the analysis of EEG indicators characterizing the FS of the central nervous system at different levels of PFA using visual and computer analysis. Materials and methods. Object - 331 archival EEGS of workers of hazardous radiation industries. The researchers determined the level of adaptation of employees using psychological, psychophysical, and physiological techniques. We conventionally recorded the EEG at rest and functional loads. In addition, scientists used a visual analysis and computer evaluation of the spectral power of EEG biopotentials in the processing. Results. With the help of visual analysis, we identified diagnostic features reflecting different levels of psychophysiological adaptation and functional activity of structural and functional formations of the central nervous system. It is possible to determine the role of structural and functional formations in forming a low level of adaptation and formulate prognostic criteria for adaptation. Researchers have identified some mechanisms of these criteria based on the evaluation results of the spectral power of EEG biopotentials. Conclusions. We identified four abnormal indicators in the EEG: "Type IV EEG", "Unstable EEG dynamics", "High index of β1 activity", "Presence of flashes of bilateral synchronous waves". These indicators indicate the presence of violations of the central regulation of the cardiovascular system and dysfunctional changes in the structures of the limbic-reticular complex. Therefore, we consider it as a criterion of a low level of PFA. The identification in the EEG of persons with a high level of PFA electroencephalographic norm indicates the absence of violations of the central regulation of the cardiovascular system and dysfunctional changes in the structures of the limbic-reticular complex. Researchers consider this a sign of a high probability of these individuals performing professional activities with a low risk of emergencies due to reduced adaptation.

Bioelectric Activity of the Brain in the Operational Personnel of the Russian Nuclear Power Plant with a Low Level of Psychophysiological Adaptation

2021 ◽  
Vol 66 (2) ◽  
pp. 29-35
Author(s):  
F. Torubarov ◽  
Z Zvereva ◽  
S. Luk'yanova
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Cardiovascular System ◽  
Functional Activity ◽  
Main Role ◽  
Central Regulation ◽  
Bioelectric Activity ◽  
Low Level ◽  
The Central Nervous System ◽  
The Brain

Purpose: The aim is to study the bioelectric activity of the brain in the operational workers of the Novovoronezh and Beloyarsk nuclear power plants with a low level of psychophysiological adaptation. Material and methods: An EEG study of 101 operational employees of the NPP was conducted, visual and spectral analyses were used. EEG indicators of individuals with a low level of psychophysiological adaptation and low functional activity of structural and functional formations of the central nervous system were compared with those of individuals with a high level of adaptation, high functional activity of structural and functional formations of the central nervous system. Results: Visual analysis of individuals with a low level of psychophysiological adaptation revealed abnormal EEG indicators, indicating functional disorders of the central nervous system. The greatest violations were revealed in the structural and functional formation responsible for the central regulation of the cardiovascular system. A comparative assessment of the spectral power of the EEG at different levels of psychophysiological adaptation revealed a state of tension (tense adaptation) observed in individuals with both low and high levels of adaptation. The similarity between the structural and functional formation "central regulation of the cardiovascular system" with low functional activity and a low level of psychophysiological adaptation in terms of the number of abnormal EEG indicators can be considered as evidence of its greatest contribution to the formation of a low level of adaptation.The evaluation of interhemispheric interactions in structural and functional formations at their low and high activity, as well as at low and high levels of adaptation, suggested that the formation of a high level of psychophysiological adaptation as an integral characteristic of the main role played by the formation of the "Cortex" and "central regulation of the cardiovascular system". In the formation of a low level of psychophysiological adaptation as an integral characteristic, the main role is played by the formations "cortex" and "cortical-subcortical interaction". Conclusion: A violation of the bioelectric activity of the brain may be one of the pathogenetic mechanisms of reduced adaptation. The presence of statistically significant differences in EEG indicators in individuals with low and high levels of adaptation, revealed by visual and spectral analysis, allows us to consider these indicators as informative not only in terms of identifying deviations in the diagnosis of functional disorders, but also in assessing the effectiveness of rehabilitation and health measures.

Musculoskeletal injuries in children

2011 ◽  
Author(s):  
Tim Theologis
Keyword(s):  
At Risk ◽  
Central Nervous System ◽  
Nervous System ◽  
Cardiovascular System ◽  
Musculoskeletal Injuries ◽  
Characteristic Pattern ◽  
Growth Disturbance ◽  
Hypovolaemic Shock ◽  
The Central Nervous System ◽  
K Wires

♦ In children, bone is more flexible and heals faster than in adults but is at risk of growth disturbance. It is also capable of remodelling♦ The physis is weaker than the structures around it and therefore is liable to disruption in trauma♦ The possibility of injuries as a result of abuse must be considered in children and have a characteristic pattern♦ In poly trauma, children are more susceptible to hypothermia. Abdominal viscera and the cranium are more vulnerable. However, the central nervous system has more scope for recovery, and the cardiovascular system has an excellent capacity for coping with hypovolaemic shock♦ A reliable specific paediatric score should be used to plan treatment♦ The management of fractures is more likely to involve traction, plaster, and K-wires.

scholarly journals Analyses of temporal regulatory elements of the prosaposin gene in transgenic mice

2003 ◽  
Vol 370 (2) ◽  
pp. 557-566 ◽  
Author(s):  
Ying SUN ◽  
David P. WITTE ◽  
Peng JIN ◽  
Gregory A. GRABOWSKI
Keyword(s):  
Spinal Cord ◽  
Central Nervous System ◽  
Nervous System ◽  
Transgenic Mice ◽  
Peak Level ◽  
Regulatory Elements ◽  
Low Level ◽  
The Central Nervous System ◽  
Flanking Region ◽  
The Brain

The expression of prosaposin is temporally and spatially regulated at transcriptional and post-translational levels. Transgenic mice with various 5′-flanking deletions of the prosaposin promoter fused to luciferase (LUC) reporters were used to define its temporal regulatory region. LUC expression in the transgenic mice carrying constructs with 234bp (234LUC), 310bp (310LUC) or 2400bp (2400LUC) of the 5′-flanking region was analysed in the central nervous system and eye throughout development. For 310LUC and 2400LUC, low-level LUC activity was maintained until embryonal day 18 in brain, eye and spinal cord. The peak level of LUC activity was at birth, with return to a plateau (1/3 of peak) throughout adulthood. Deletion of the region that included the retinoic acid-receptor-related orphan receptor (RORα)-binding site and sequence-specific transcription factor (Sp1) cluster sites (44—310bp) suppressed the peak of activity. By comparison, the peak level for 234LUC was shifted 2 weeks into neonatal life in the brain, but not in the eye, and no peak of activity was observed in the spinal cord. The endogenous prosaposin mRNA in eye, spinal cord and cerebellum had low-level expression before birth and continued to increase into adulthood. In cerebrum, the endogenous mRNA showed similar expression profile to constructs 310LUC, 2400LUC and 234LUC, with the peak expression at 1 week and a decreased level in adult. In the brain of the newborn, 2400LUC was highly expressed in the trigeminal ganglion and brain stem regions when compared with the generalized expression pattern for endogenous prosaposin mRNA. These results suggest that the modifiers (RORα- and Sp1-binding sites) residing within 310bp of the 5′-flanking region mediate developmental regulation in the central nervous system and eye. Additional regulatory elements outside the 5′ region of the 2400bp promoter fragment appear to be essential for the physiological control of the prosaposin locus.

Functional Response of the Central Nervous System of Dogs to Low-Level Irradiation

1966 ◽  
Vol 5 (1) ◽  
pp. 177-184 ◽  
Author(s):  
C. F. Sams ◽  
S. Endo ◽  
R. B. Aird ◽  
G. D. Adams ◽  
G. L. Ellman
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Functional Response ◽  
Low Level ◽  
The Central Nervous System

Maceste and its importance in the treatment of diseases of the nervous system

1927 ◽  
Vol 23 (4) ◽  
pp. 464-464
Author(s):  
V. I. Znamensky
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Cardiovascular System ◽  
Peripheral Nervous System ◽  
Tabes Dorsalis ◽  
The Central Nervous System ◽  
The Brain

According to V. I. Znamensky indicated for treatment in Matsesta: 1) diseases of the peripheral nervous system, -neuralgia, neuritis; 2) diseases of the central nervous system connected with disorders of the cardiovascular system, - hemiplegia and hemiparesis due to thrombosis and embolism; (treatment of acute forms of the mentioned diseases, it goes without saying, is contraindicated); 3) Luetic diseases,-vascular syphilis of the brain, lues cerebrospinalis, meningo-myelitis, tabes dorsalis incipiens and Luetic radiculitis (here; baths, giving increase of metabolism and excretions, make possible mercury treatment with impunity); 4) remnants of lethargic encephalitis.

scholarly journals Microglial cell depletion is fatal with low level picornavirus infection of the central nervous system

2019 ◽  
Vol 25 (3) ◽  
pp. 415-421 ◽  
Author(s):  
John Michael S. Sanchez ◽  
Ana Beatriz DePaula-Silva ◽  
Daniel J. Doty ◽  
Amanda Truong ◽  
Jane E. Libbey ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Microglial Cell ◽  
Cell Depletion ◽  
Low Level ◽  
The Central Nervous System ◽  
Picornavirus Infection

scholarly journals Vasoactive effects of sex hormones

1997 ◽  
Vol 43 (2) ◽  
pp. 45-53 ◽  
Author(s):  
A. N. Karachentsev ◽  
P. V. Sergeev
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Cardiovascular System ◽  
Sex Hormones ◽  
Scientific Literature ◽  
Circulatory System ◽  
Vascular Wall ◽  
Biologically Active ◽  
The Central Nervous System ◽  
Active Substances

Extensive experimental and clinical material cited in the modern scientific literature indicates the effect of sex hormones on the cardiovascular system and the need to take into account changes in its activity during therapy with drugs containing these biologically active substances [3, 5, 7, 71]. Along with the numerous compounds mediated through the structures of the central nervous system and circulating in the circulatory system, the genomic vasoactive effects of all steroid compounds, including sex hormones, can be realized due to the direct effect on the vascular wall [55, 66, 71, 75].

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