ALGORITHM FOR EARLY DIAGNOSIS AND PREVENTION OF PROFESSIONAL SENSORINEURAL HEARING LOSS

Author(s):  
E.A. Preobrazhenskaya ◽  
◽  
A.V. Sukhova ◽  
E.N. Kryuchkova

Abstract: The aim of the study is to develop an algorithm for early diagnosis and prevention of professional neurosensory hearing elasticity (PNST). A comprehensive audiological survey of 600 miners aged 37 to 58, with 10 to 35 years of experience in noise conditions above the PDU for 7-21 dBA (class 3.1-3.3) was carried out. Based on the studies, an algorithm of early diagnosis and prevention of PNST, consisting of 3 blocks: I - hygienic (assessment of working conditions and risk categorization), II - clinical diagnostic, based on modern audiological methods of hearing research with the selection of diagnostic markers of risk of PNST, III - preventive, including the development of individual hearing preservation programs. The developed algorithm allows in 65-75% of cases to identify changes in the auditory analyzer at the preclinical stage, to clarify the nature and localization of the auditory analyzer, which is important in the development of therapeutic and preventive measures.

2015 ◽  
Vol 129 (8) ◽  
pp. 767-772 ◽  
Author(s):  
V Atchariyasathian ◽  
K Pruegsanusak ◽  
S Wongsriwattanakul

AbstractObjective:To compare the incidence of sensorineural hearing loss between those treated with docetaxel, cisplatin and 5-fluorouracil induction chemotherapy followed by carboplatin concurrent chemoradiotherapy and those treated with conventional concurrent chemoradiotherapy for advanced nasopharyngeal carcinoma.Methods:Serial pure tone audiometry was conducted in 36 nasopharyngeal carcinoma patients who were randomised into 2 groups. The first group received docetaxel, cisplatin and 5-fluorouracil induction chemotherapy followed by carboplatin concurrent chemoradiotherapy. The second group received conventional concurrent chemoradiotherapy.Results:The incidence of sensorineural hearing loss at speech frequency in the first group was 10 per cent and in the second group was 50 per cent (p = 0.0027). Bone conduction thresholds were significantly increased after completion of the treatment at 2–4 kHz in the first group and at all frequencies in the second group.Conclusion:The docetaxel, cisplatin and 5-fluorouracil induction chemotherapy regimen followed by concurrent chemoradiotherapy was associated with a lower incidence of sensorineural hearing loss than conventional concurrent chemoradiotherapy. This regimen may be the preferred choice of treatment for hearing preservation.


1979 ◽  
Vol 93 (12) ◽  
pp. 1223-1228 ◽  
Author(s):  
Israel Brama ◽  
Dan Engelhard

SummaryFOUR cases of bilateral congenital choanal atresia are presented. Three of them (75 per cent) were shown by Electric Response Audiometry (ERA) tests to have, in addition, congenital nerve deafness; and two had other congenital anomalies. Thus, congenital nerve deafness should be considered as a possible congenital anomaly associated with choanal atresia. Early diagnosis and treatment of congenital choanal atresia can prevent death from asphyxia during the neonatal period, but after surgical correction of the atresia the possible existence of additional anomalies has to be determined and treated.By the use of electric response audiometry we are able to detect sensorineural hearing loss during the neonatal period and can plan the rehabilitation of deaf infants.


2001 ◽  
Vol 125 (5) ◽  
pp. 544-551 ◽  
Author(s):  
Rick A. Friedman ◽  
Bradley W. Kesser ◽  
William H. Slattery ◽  
Derald E. Brackmann ◽  
William E. Hitselberger

2019 ◽  
Vol 8 (1) ◽  
pp. 39-42
Author(s):  
Alexander Zinchuk ◽  
Nadiya Prykuda

Introduction. Lyme borreliosis (LB) is endemic spirochetosis with a transmission mechanism, which is often marked by a durable, recurrent course with multiple organ damages. LB is characterized by the appearance of migrating erythema at the site of tick bite. Durable persistence of the agent promotes disease progressing and occurrence of serious complications related to the nervous system, the heart and the locomotive apparatus. Among infrequent and especially dangerous complications of LB is damage to the hearing apparatus with the development of sensorineural deafness – hearing loss, which develops within 24 hours due to function impairment of the internal ear or auditory nerve. That infectious diseases account for 12.8-13% of numerous causes of sensorineural deafness development. Most frequently, the disease caused by B. burgdorferi is mentioned. Aim. To analyze the clinical case of Lyme borreliosis complicated by the sensorineural hearing loss. Materials and methods. The analysis of clinical-laboratory and instrumental data of the patient with Lyme borreliosis, whose course of the disease was complicated by sensorineural hearing loss. The patient received care at Lviv Regional Infectious Diseases Clinical Hospital (LRIDCH). Results. The article presents a clinical case of Lyme borreliosis, complicated by sensorineural hearing loss, which appeared on the 15th day from the onset of erythema annulare in the patient. Hearing recovery in the patient could not be achieved via administration of etiotropic treatment (2.0 g/per day of ceftriaxone for 28 days), which was likely associated with late visit of the patient for medical aid. Conclusions. Sensorineural hearing loss is one of the rare, but severe lesions of auditory analyzer in LB. Hearing improvement after antibiotic therapy is possible in certain cases in early treatment.


1995 ◽  
Vol 104 (9_suppl2) ◽  
pp. 342-345 ◽  
Author(s):  
N. M. Young ◽  
J. C. Johnson ◽  
M. B. Mets ◽  
T. C. Hain

Usher's syndrome (US) is an autosomal recessive disorder characterized by congenital sensorineural hearing loss and retinitis pigmentosa. The majority of affected individuals have severe to profound sensorineural hearing loss and are therefore potential cochlear implant candidates. A goal of our otology program has been early identification and implantation of children with US. At our center, early diagnosis of US has been achieved by comprehensive ophthalmologic evaluation including electroretinography. Four of our 19 pediatric cochlear implant recipients with congenital sensorineural hearing loss were identified with US and implanted prior to the onset of signs or symptoms of visual loss. All children have received measurable benefit from cochlear implantation. In light of the dual sensory deficits present in US, the need for early diagnosis and cochlear implantation is of special importance in this population.


2018 ◽  
Vol 2018 ◽  
pp. 1-11 ◽  
Author(s):  
Min Yong Lee ◽  
Yong-Ho Park

Sensorineural hearing loss is caused by the loss of sensory hair cells (HCs) or a damaged afferent nerve pathway to the auditory cortex. The most common option for the treatment of sensorineural hearing loss is hearing rehabilitation using hearing devices. Various kinds of hearing devices are available but, despite recent advancements, their perceived sound quality does not mimic that of the “naïve” cochlea. Damage to crucial cochlear structures is mostly irreversible and results in permanent hearing loss. Cochlear HC regeneration has long been an important goal in the field of hearing research. However, it remains challenging because, thus far, no medical treatment has successfully regenerated cochlear HCs. Recent advances in genetic modulation and developmental techniques have led to novel approaches to generating HCs or protecting against HC loss, to preserve hearing. In this review, we present and review the current status of two different approaches to restoring or protecting hearing, gene therapy, including the newly introduced CRISPR/Cas9 genome editing, and stem cell therapy, and suggest the future direction.


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