Estimation of the 3-Day Faecal Fat Excretion and Fat Concentration as a Differential Test of Malabsorption and Maldigestion

1987 ◽  
Vol 22 (1) ◽  
pp. 91-96 ◽  
Author(s):  
N. Thorsgaard Pedersen ◽  
H. Halgreen ◽  
H. Worning
1967 ◽  
Vol 119 (6) ◽  
pp. 573-576 ◽  
Author(s):  
E. C. Raffensperger
Keyword(s):  

2007 ◽  
Vol 293 (2) ◽  
pp. G510-G516
Author(s):  
Karin E. R. Gooijert ◽  
Rick Havinga ◽  
Alida R. Oosterloo-Duinkerken ◽  
Enge E. A. Venekamp-Hoolsema ◽  
Folkert Kuipers ◽  
...  

Erythropoietic protoporphyria (EPP) is characterized by toxic accumulation of the hydrophobic compound protoporphyrin (PP). Ferrochelatase-deficient ( fch/ fch) mice are an animal model for human EPP. Recently, we have demonstrated that the accumulation of another hydrophobic compound, unconjugated bilirubin, could effectively be treated by stimulation of fecal fat excretion. We investigated whether stimulation of fecal fat excretion enhanced the disposal of PP in fch/ fch mice. Fch/ fch mice were fed for 8 wk with a high-fat diet (16 wt% fat; control) or with the high-fat diet mixed with either a nonabsorbable fat (sucrose polyester) or the intestinal lipase inhibitor orlistat. The effects of the treatments on fecal excretion of fat and PP and on hepatic PP concentrations were compared with control diets. Fecal fat excretion in fch/ fch mice on a high-fat diet was higher than in mice on a low-fat diet (+149%, P < 0.05). Sucrose polyesters and orlistat increased fecal fat excretion even more, up to sixfold of control values. However, none of the different treatments affected fecal PP excretion or hepatic PP concentration. Treatment of fch/ fch mice with a high-fat diet, a nonabsorbable fat diet, or with orlistat increased the fecal excretion of fat but did not increase fecal PP excretion or decrease hepatic PP concentration. The present data indicate that accumulation of PP is not amenable to stimulation of fecal fat excretion.


2001 ◽  
Vol 43 (2) ◽  
pp. 97-111 ◽  
Author(s):  
Herman Feifel ◽  
Stephen Strack

This study examined the death attitudes of a number of prominent thanatologists over a 15-year span. In 1973, 40 (30 men, 10 women) invited participants at a conference on death and dying were surveyed concerning their attitudes toward dying and death using Feifel's Death Attitudes Questionnaire, a Death Semantic Differential Test, and a Death Metaphors Test. Fifteen years later, 25 (62.5 percent) of these individuals again gave their responses to the three measures. Analyses were limited to basic group comparisons because the original raw data were unavailable. Respondents were primarily behavioral scientists (64 percent), but sizeable minorities were from medicine/nursing (24 percent) and religion/philosophy (12 percent). They were about equally divided in the religious (45 percent) versus non-religious (55 percent) categories, and rated themselves as being fairly satisfied with themselves and life in general. Almost two-thirds reported some fear of death (64 percent at both time points), and only 20 percent indicated that the idea of their own death was “easy to accept.” Most (60–64 percent) reported a fear of the personal consequences of death, including pain and an inability to have experiences or complete projects, with the next most pervasive fear (36–40 percent) being the consequences to loved ones, including pain, loss, and financial difficulties. Concerning what occurs after death, about half of the respondents (48–52 percent) indicated that death is the end of existence, another 24–30 percent were uncertain and 16–17 percent believed in the continued existence of a soul. Death attitudes were remarkably stable over the 15-year interval. The major difference found was a lessening of death fear from 1973 to 1988 ( p < .002), that subjects attributed primarily to their ongoing conversations about death and dying (56 percent), and the deaths of family and friends (32 percent).


2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Amin Mousavi ◽  
Zahra Sharafi ◽  
Abdolreza Mahmoudi ◽  
Hadi Raeisi Shahraki

Background. The Oxford Happiness Inventory (OHI) is a self-report tool to measure happiness. A brief review of previous studies on OHI showed the lack of evaluation of OHI fairness/equivalence in measuring happiness among identified groups. Methods. To examine the psychometric properties and measurement invariance of the OHI, responses of 500 university students were analyzed using item response theory and ordinal logistic regression (OLR). Relevant measures of effect size were utilized to interpret the results. Differential test functioning was also evaluated to determine whether there is an overall bias at the test level. Results. OLR analysis detected four items across gender and two items across marital status to function differentially. An assessment of effect sizes implied negligible differences for practical considerations. Conclusions. This study was a significant step towards providing theoretical and practical information regarding the assessment of happiness by presenting adequate evidence regarding the psychometric properties of OHI.


2019 ◽  
Vol 20 (1) ◽  
pp. 57-77 ◽  
Author(s):  
Steven L. Wise ◽  
James Soland, ◽  
Yuanchao Bo
Keyword(s):  

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