Effect of Amla fruit (Emblica officinalisGaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients

2011 ◽  
Vol 62 (6) ◽  
pp. 609-616 ◽  
Author(s):  
Muhammad Shoaib Akhtar ◽  
Ayesha Ramzan ◽  
Amanat Ali ◽  
Maqsood Ahmad
2020 ◽  
Vol 31 (2) ◽  
pp. 64-68
Author(s):  
Rusdiana ◽  
Sry Suryani Widjaja ◽  
Mila Hayati Daulay ◽  
Almaycano Ginting

Background: The global prevalence of type 2 diabetes mellitus is increasing steadily and diabeticretinopathy is one of the microvascular complications of diabetes mellitus. This research aims tocompare different clinical and metabolic parameters among type 2 diabetic patients with and withoutdiabetic retinopathy. Methods: This cross-sectional study was done at various primary health care centers in Medan cityand the surrounding areas in North Sumatera from May to July 2020. Collected medical data includedblood pressure, body mass index, duration of disease, family history and medical treatment. Laboratorydata included blood glucose, glycated hemoglobin (HbA1c) and lipid profile. Diabetic retinopathy wasdetected by funduscopic examination by an ophthalmologist. Results: Total patients were 88 and 26 had retinopathy. There was significant difference betweenthe average blood pressure, blood glucose and HbA1C values among patients with type 2 diabetesmellitus with and without retinopathy (p<0.005). But, there was no significant difference between theaverage body mass index (BMI), abdominal circumference and lipid profile. Conclusion: Study showed that type 2 diabetic patients with retinopathy had increased blood glucoselevels and HbA1c than patients without retinopathy. Bangladesh J Medicine July 2020; 31(2) :64-68


2019 ◽  
Vol 24 (4) ◽  
pp. 420-425
Author(s):  
Somaye Sadat Hoseini ◽  
Seyed Alireza Saadatjoo ◽  
Samaneh Nakhaee ◽  
Alireza Amirabadizadeh ◽  
Maryam Rezaie ◽  
...  

2020 ◽  
Vol 7 (2) ◽  
Author(s):  
Najah RH ◽  
Mohammad AAH ◽  
Ammar RMR

Introduction: Evidence has long existed regarding the relationship between oxidative stress and diabetes. The present study was conducted to assess the effect of atorvastatin on selected oxidative stress parameters in the form of reduced glutathione (GSH), lipid peroxidation byproduct malondialdehyde (MDA) levels, glutathione –S- transferase (GST) activity and catalase (CAT) activity) and its effect on lipid profile (total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL), low density lipoprotein (LDL) and very low density lipoprotein (VLDL) in dyslipidaemic type 2 diabetic patients . Materials and Methods: Fifty nine dyslipidaemic type 2 diabetic patients were included in this study. Full history was taken and general examination of patients was performed. Patients studied were taking glibenclamide (an oral hypoglycaemic drug) during the study as a treatment for their disease. These patients were followed up for 60 days and divided randomly into 2 groups. Group I (n = 31): no drug was given and served as dyslipidaemic diabetic control. Group II (n = 28): received atorvastatin tablets 20 mg once daily at night. Of the 59 Fifty patients, 46 completed the study while 13 patients withdrew. This is due to non compliance of the patients. Blood samples were drawn from the patients at the beginning and after 60 days of follow up between 8:30 & 10:30 am after at least 12-14 hours fast. Fasting blood glucose, lipid profile, selected oxidative stress parameters (GSH, MDA levels, GST and CAT activities) were measured. Renal and hepatic functions were also assessed. Results: This study revealed that: atorvastatin treatment increased serum GSH; reduced MDA levels significantly while did not significantly affect CAT and GST activity. In atorvastatin treatment, TC, TG, LDL and VLDL decreased significantly while HDL increased significantly. Conclusion: There was insignificant correlations between atorvastatin induced changes in the oxidation markers and the observed changes of the lipid profile.


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