Improvement of health status evaluated by Arthritis Impact Measurement Scale 2 (AIMS-2) and Short Form-36 (SF-36) in patients with rheumatoid arthritis treated with tocilizumab

2013 ◽  
Vol 23 (2) ◽  
pp. 276-283 ◽  
Author(s):  
Mie Fusama ◽  
Hideko Nakahara ◽  
Yoshimasa Hamano ◽  
Masayuki Nishide ◽  
Keisuke Kawamoto ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Health Status ◽  
Short Form ◽  
Measurement Scale ◽  
Impact Measurement ◽  
Arthritis Impact Measurement Scale ◽  
Short Form 36 ◽  
Sf 36

scholarly journals Self Management Behaviors in Rheumatoid Arthritis Patients and Associated Factors in Tehran 2013

2015 ◽  
Vol 8 (3) ◽  
pp. 156 ◽  
Author(s):  
Mosharafeh Chaleshgar Kordasiabi ◽  
Maassoumeh Akhlaghi ◽  
Mohammad Hossein Baghianimoghadam ◽  
Mohammad Ali Morowatisharifabad ◽  
Mohsen Askarishahi ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Health Status ◽  
Associated Factors ◽  
Demographic Variables ◽  
Self Management ◽  
Measurement Scale ◽  
Unknown Etiology ◽  
Physician Global Assessment ◽  
Impact Measurement ◽  
Management Behaviors

<p><strong>INTRODUCTION:</strong> Rheumatoid Arthritis (RA) is a systemic, autoimmune and inflammatory disease with an unknown etiology that is associated with progressive joint degeneration, limitation of physical activity and disability. The aim of the study was to evaluate self-management behaviors and their associated factors in RA patients.</p><p><strong>MATERIAL &amp; METHOD: </strong>This cross-sectional study was performed in 2013 on185 patients in Iran. Data were selected through convenient sampling. The collected data included demographic variables, disease related variables, Arthritis Impact Measurement Scale 2 (AIMS-2SF), and Self-Management Behaviors (SMB). Data were analyzed by SPSS17 using Spearman correlation and logistic regression test.</p><p><strong>RESULT:</strong> In this study drug management, regular follow-up, and food supplement were used as the most frequently applied SMB and aquatic exercise, diet, massage therapy, and relaxation were the least common SMBs. Age, education, health status, occupation, marital status, sex, DAS28 (Disease Activity Score 28 joints), and PGA (Physician Global Assessment) were significantly related with SMB.</p><p><strong>CONCLUSION:</strong> The result of the study highlight the influence of demographic variables, health status, and disease related data on SMB. Thus, more studies are required to find factors influencing SMB in order to improve SMB.</p>

scholarly journals Improved pain, physical functioning and health status in patients with rheumatoid arthritis treated with CP-690,550, an orally active Janus kinase (JAK) inhibitor: results from a randomised, double-blind, placebo-controlled trial

2009 ◽  
Vol 69 (2) ◽  
pp. 413-416 ◽  
Author(s):  
J H Coombs ◽  
B J Bloom ◽  
F C Breedveld ◽  
M P Fletcher ◽  
D Gruben ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Health Status ◽  
Short Form ◽  
Controlled Trial ◽  
Health Assessment ◽  
Janus Kinase ◽  
Inadequate Response ◽  
Double Blind ◽  
Sf 36 ◽  
Factor Α

Objectives:To determine the efficacy of CP-690,550 in improving pain, function and health status in patients with moderate to severe active rheumatoid arthritis (RA) and an inadequate response to methotrexate or a tumour necrosis factor α inhibitor.Methods:Patients were randomised equally to placebo, CP-690,550 5, 15 or 30 mg twice daily for 6 weeks, with 6 weeks’ follow-up. The patient’s assessment of arthritis pain (pain), patient’s assessment of disease activity, Health Assessment Questionnaire-Disability Index (HAQ-DI) and Short Form-36 (SF-36) were recorded.Results:At week 6, significantly more patients in the CP-690,550 5, 15 and 30 mg twice-daily groups experienced a 50% improvement in pain compared with placebo (44%, 66%, 78% and 14%, respectively), clinically meaningful reductions in HAQ-DI (⩾0.3 units) (57%, 75%, 76% and 36%, respectively) and clinically meaningful improvements in SF-36 domains and physical and mental components.Conclusions:CP-690,550 was efficacious in improving the pain, function and health status of patients with RA, from week 1 to week 6.

scholarly journals The Relationship between Beliefs about Pain and Functioning with Rheumatologic Conditions

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Tracey Pons ◽  
Edward Shipton ◽  
Rodger Mulder
Keyword(s):  
Response Rate ◽  
Short Form ◽  
Demographic Data ◽  
Measurement Scale ◽  
Psychological Pain ◽  
Impact Measurement ◽  
Pain Mechanisms ◽  
Arthritis Impact Measurement Scale ◽  
Pain Beliefs ◽  
The Relationship

Pain beliefs influence understanding of pain mechanisms and outcomes. This study in rheumatologic conditions sought to determine a relationship between beliefs about pain and functioning. Participants in Arthritis New Zealand’s (ANZ) exercise and education programmes were used. Demographic data and validated instruments used included the Arthritis Impact Measurement Scale 2nd version-Short Form (AIMS2-SF) to measure functioning, and two scales of organic and psychological beliefs in Pain Beliefs Questionnaires (PBQ) to measure pain beliefs. 236 Members of ANZ were surveyed anonymously with AIMS2-SF and PBQ, with a 61% response rate; 144 responses were entered into the database. This study used α of 0.05 and a 1-β of 0.8 to detect for significant effect size estimated to ber=0.25. Analysis revealed a significant relationship between organic beliefs scale of PBQ and functioning of AIMS2-SF, with anrvalue of 0.32 andPvalue of 0.00008. No relationship was found between psychological beliefs scale of PBQ and AIMS2-SF. Organic pain beliefs are associated with poorer functioning. Psychological pain beliefs are not. Beliefs might have been modified by ANZ programmes. Clinicians should address organic pain beliefs early in consultation. Causal links between organic pain beliefs and functioning should be clarified.

Validity of health status measurement with the Dutch Arthritis Impact Measurement Scale 2 in individuals with severe haemophilia

Haemophilia ◽  
2001 ◽  
Vol 7 (2) ◽  
pp. 190-197 ◽  
Author(s):  
E. W. P. De Joode ◽  
N. L. U. Van Meeteren ◽  
H. M. Van Den Berg ◽  
P. De Kleijn ◽  
P. J. M. Helders
Keyword(s):  
Health Status ◽  
Measurement Scale ◽  
Severe Haemophilia ◽  
Impact Measurement ◽  
Health Status Measurement ◽  
Arthritis Impact Measurement Scale

scholarly journals Health status has improved more in women than in men with rheumatoid arthritis from 1994 to 2009: results from the Oslo rheumatoid arthritis register

2013 ◽  
Vol 74 (1) ◽  
pp. 148-155 ◽  
Author(s):  
C Austad ◽  
T K Kvien ◽  
I C Olsen ◽  
T Uhlig
Keyword(s):  
Rheumatoid Arthritis ◽  
Gender Differences ◽  
Health Status ◽  
Gender Gap ◽  
Mixed Model ◽  
Short Form ◽  
Patient Reported Outcome Measures ◽  
Pain Patient ◽  
Sf 36 ◽  
Patient Reported

ObjectiveTo examine changes in patient reported outcome measures (PROs) over 15 years in a representative population of patients with rheumatoid arthritis (RA), with a particular focus on gender differences.Patients and methodsPatients in the Oslo RA register filled in questionnaires including the Modified Health Assessment Questionnaire (MHAQ), the Short-Form 36 (SF-36) with physical (PCS) and mental component summaries and derived utility (SF-6D), visual analogue scales (VAS) for pain, patient global assessment of disease (PtGA) and fatigue, and checklists of medication commonly used in the treatment of RA. Data were collected at five time points during a 15-year period from 1994. Mixed model analyses were used to analyse longitudinal changes in PROs from 1994 to 1996, 2001, 2004 and 2009.ResultsData were available from 829–1025 RA patients at each time point. PROs were statistically significantly improved from 1994 to 2009 (MHAQ, SF-36 PCS, SF-6D, pain VAS, PtGA VAS and fatigue VAS; all p<0.001), and also with clinically important improvement. Men reported significantly better health status than women in 1994, but women improved significantly more than men over 15 years with a reduction of the gender gap in 2009. Antirheumatic medication was increasingly used over 15 years with no gender differences.ConclusionsRA patients reported statistically significantly improved health status for most PROs from 1994 to 2009. Women improved most, and although they still reported higher disease impact than men, the gender differences were small at the final data collection in 2009.

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