Expression of zinc-finger protein X-linked, ZFX, is associated with enhanced survival in patients with breast cancer.
Keyword(s):
Stage Iv
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We mined published tumor transcriptome data with paired survival data to discover genes associated with survival outcomes in breast cancer (1, 2). We found that the zinc-finger protein X-linked ZFX (3, 4) was among the genes most differentially expressed in both primary and metastatic tumor tissues when comparing tumor transcriptomes based on survival at 24 months. ZFX expression was significantly higher in the metastatic tumors of patients surviving greater than 24 months, suggesting that increased ZFX expression confers a survival benefit to patients with stage IV metastatic breast cancer.
2021 ◽
2020 ◽
Keyword(s):
2020 ◽
Keyword(s):
Keyword(s):
Keyword(s):
2020 ◽
Keyword(s):
2021 ◽
Vol 5
(1)
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pp. 97-110