The potential role of protein leverage in the US obesity epidemic
The protein leverage model of obesity posits that decreasing the protein content of the diet leads to compensatory increases in total energy intake to maintain an absolute amount of protein consumed. Increased energy intake thereby results in weight gain. According to data from food balance sheets from the United Nations Food and Agriculture Organization, while the absolute protein content of the US food supply has increased since the early 1970s, the fraction of available calories from protein has decreased by ~1% due to greater increases in available carbohydrate and fat. Surprisingly, even such a small decrease in the protein fraction of the food supply has the potential to result in large increases in energy intake according to the protein leverage model. Therefore, while the protein leverage effect is unlikely to fully explain the obesity epidemic, its potential contribution should not be ignored.