Can the Edinburgh Postnatal Depression Scale be used to screen for anxiety in the perinatal period? A factor analysis of high-risk and community samples
Background: Timely and accurate detection of perinatal mental health problems is essential for the wellbeing of both mother and child. Growing evidence has suggested that the Edinburgh Postnatal Depression Scale (EPDS) is not a unidimensional measure of perinatal depression, but can be used to screen for anxiety disorders.Methods: We aimed to assess the factor structure of the EPDS in 3 different groups of women: n=266 pregnant women at high-risk of depression (“Perinatal Stress Study”), n=471 pregnant women from a community sample, and n=637 early postnatal women from a community sample (“developing Human Connectome Project”). Exploratory factor analysis (40% of each sample) and confirmatory factor analysis (60% of each sample) were performed. The relationship between EPDS scores and history of mental health was investigated. Results: Results suggested that a 3-factor model (depression, anxiety, and anhedonia) is the most appropriate across groups. The anxiety subscale (EPDS 3A) emerged consistently and was related to maternal history of anxiety disorders. Total EPDS score was related to history of mental health problems. Limitations: Although data were collected on maternal history of mental health, there was no standardized diagnostic interview administered to assess the relationship between EPDS 3A and a current diagnosis of anxiety disorder. Conclusions: A better understanding of the multi-factorial structure of the EPDS can inform diagnosis and management of women in the prenatal and postnatal period. The EPDS 3A could be used to provide initial screening information for anxiety in situations where a validated anxiety questionnaire is not administered.