scholarly journals Age-related decline in item but not spatiotemporal associative memory for a real-world event

2018 ◽  
Author(s):  
Nicholas Diamond ◽  
Kristoffer Romero ◽  
Nivethika Jeyakumar ◽  
Brian Levine
Keyword(s):  
Older Adults ◽  
Episodic Memory ◽  
Associative Memory ◽  
Real World ◽  
Item Memory ◽  
Discrimination Accuracy ◽  
Core Component ◽  
Museum Exhibit ◽  
Item Order ◽  
Age Related

Normal aging is typically associated with reduced ability to reconstruct the spatiotemporal context of past events, a core component of episodic memory. However, little is known about our ability to remember the order of events comprising extended real-world experiences and how this ability changes with age. We leveraged the richness and structure of a museum exhibit to address this question. Three months after visiting the exhibit, 141 adults aged 18-84 completed a test of spatiotemporal order memory and old/new recognition using pictures from the exhibit and similar lures, from which measures of associative and item memory were derived. Order discrimination accuracy was modulated by inter-item order and distance in younger and older adults, extending findings from recognition of laboratory stimuli at short delays to remote real-world experiences. In contrast to established findings from laboratory-based assessments, we observed a significant effect of aging on item memory driven byincreased lure susceptibility, but no age-related reduction in spatiotemporal associative memory. These findings present novel insights into different components of memory for real-world experiences at naturalistic timescales and across the lifespan.

The effects of stereotype threat on the associative memory deficit of older adults

2015 ◽  
Author(s):  
◽  
Matthew S. Brubaker
Keyword(s):  
Older Adults ◽  
Stereotype Threat ◽  
Associative Memory ◽  
Memory Performance ◽  
Memory Deficit ◽  
Item Memory ◽  
University Of Missouri ◽  
Age Related ◽  
Associative Deficit ◽  
Negative Effect

[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] One of the suggestions made in the literature regarding older adults' episodic memory decline is that it is caused by their reduced ability to bind together components of an episode and retrieve the binding (termed an associative deficit). The purpose of the current research is to assess whether the age-related associative memory deficit is at least partially mediated by stereotype threat, which has been shown to negatively affect performance on a wide variety of cognitive tasks, including memory performance of older adults. To date the effects of stereotype threat on older adults' memory performance have only been shown using tests of item memory, and between subject manipulations. The question assessed in the current research is whether older adults' associative memory will be affected by stereotype threat more than item memory, rendering it one potential factor underlying the associative deficit. To answer this question, three experiments were conducted, which used an item-associative recognition memory paradigm while manipulating stereotype threat both within and between subjects. The first two experiments attempted to establish the baseline effect by directly comparing item and associative memory in younger and older adults under induced stereotype threat, reduced stereotype threat, and no stereotype threat (i.e. control) conditions. While a baseline age-related associative deficit was not shown in the control condition, inducing stereotype threat did have a significant negative effect on older adults' associative memory performance without affecting item memory performance -- suggesting that stereotype threat does increase the age-related associative deficit. The third experiment further assessed the stage of processing -- encoding, retrieval, or both -- during which the effect of stereotype threat on older adults' memory occurs. Results showed that when stereotype threat was induced only at retrieval, memory performance was in line with performance with the reduced stereotype threat and control conditions, suggesting that this effect of stereotype threat occurs primarily during encoding of the information.

Dopamine Receptor Genes Modulate Associative Memory in Old Age

2017 ◽  
Vol 29 (2) ◽  
pp. 245-253 ◽  
Author(s):  
Goran Papenberg ◽  
Nina Becker ◽  
Beata Ferencz ◽  
Moshe Naveh-Benjamin ◽  
Erika J. Laukka ◽  
...  
Keyword(s):  
Older Adults ◽  
Episodic Memory ◽  
Associative Memory ◽  
Genetic Risk ◽  
Genetic Risk Score ◽  
Memory Task ◽  
Population Based ◽  
Item Memory ◽  
Nucleotide Polymorphisms ◽  
Genetic Score

Previous research shows that associative memory declines more than item memory in aging. Although the underlying mechanisms of this selective impairment remain poorly understood, animal and human data suggest that dopaminergic modulation may be particularly relevant for associative binding. We investigated the influence of dopamine (DA) receptor genes on item and associative memory in a population-based sample of older adults (n = 525, aged 60 years), assessed with a face–scene item associative memory task. The effects of single-nucleotide polymorphisms of DA D1 (DRD1; rs4532), D2 (DRD2/ANKK1/Taq1A; rs1800497), and D3 (DRD3/Ser9Gly; rs6280) receptor genes were examined and combined into a single genetic score. Individuals carrying more beneficial alleles, presumably associated with higher DA receptor efficacy (DRD1 C allele; DRD2 A2 allele; DRD3 T allele), performed better on associative memory than persons with less beneficial genotypes. There were no effects of these genes on item memory or other cognitive measures, such as working memory, executive functioning, fluency, and perceptual speed, indicating a selective association between DA genes and associative memory. By contrast, genetic risk for Alzheimer disease (AD) was associated with worse item and associative memory, indicating adverse effects of APOE ε4 and a genetic risk score for AD (PICALM, BIN1, CLU) on episodic memory in general. Taken together, our results suggest that DA may be particularly important for associative memory, whereas AD-related genetic variations may influence overall episodic memory in older adults without dementia.

scholarly journals A Specificity Principle of Memory: Evidence from Aging and Associative Memory

2019 ◽  
Author(s):  
Nathaniel R. Greene ◽  
Moshe Naveh-Benjamin
Keyword(s):  
Older Adults ◽  
Episodic Memory ◽  
Associative Memory ◽  
Normal Aging ◽  
Associative Recognition ◽  
Specific Information ◽  
Old Adults ◽  
Variable Delays ◽  
Age Related ◽  
Multiple Levels

The ability to remember associations among components of an event, which is central to episodic memory, declines with normal aging. In accord with the specificity principle of memory (Surprenant & Neath, 2009), these declines may occur because associative memory requires retrieval of specific information. Guided by this principle, we endeavored to determine whether ubiquitous age-related deficits in associative memory (e.g., Naveh-Benjamin, 2000) are restricted to specific representations or extend to the gist of associations. Young and old adults (30 each in Experiment 1, 40 each in Experiment 2) studied face-scene pairs and were administered associative recognition tests following variable delays. Whereas both young and older adults could retrieve the gist of associations, older adults were impaired in their ability to retrieve more specific representations. Our results also show that associations can be retrieved from multiple levels of specificity, suggesting that episodic memory might be accessed on a continuum of specificity.

scholarly journals Semantic Relatedness Corrects the Age-Related Binding Deficit in Working Memory and Episodic Memory

2019 ◽  
Vol 75 (9) ◽  
pp. 1841-1849 ◽  
Author(s):  
Vanessa M Loaiza ◽  
Sabina Srokova
Keyword(s):  
Older Adults ◽  
Working Memory ◽  
Episodic Memory ◽  
Age Groups ◽  
Semantic Relatedness ◽  
Item Memory ◽  
Younger Adults ◽  
Age Related ◽  
Long Term Retention

Abstract Objectives It is well known that age differentially impacts aspects of long-term episodic memory (EM): Whereas a binding deficit indicates that older adults are less capable than younger adults to encode or retrieve associations between information (e.g., the pairing between two memoranda, such as lock – race), item memory is relatively intact (e.g., recognizing lock without its original pairing). Method We tested whether this deficit could be corrected by facilitating establishment of the bindings in working memory (WM) through adapting the semantic relatedness of studied pairs according to participants’ ongoing performance (Experiments 1 and 2). We also examined whether this was evident for the long-term retention of pairs that were not tested in WM (Experiment 2). Results The results revealed matched binding and item memory in WM and EM between age groups. Most importantly, older adults required increased semantic strength between word pairs to achieve similar performance to that of younger adults, regardless of whether pairs were immediately tested during the WM task. Discussion These findings indicate that relying on their superior semantic memory can correct the commonly exhibited profound deficit in binding memory in older age.

scholarly journals A Specificity Principle of Memory: Evidence From Aging and Associative Memory

2020 ◽  
Vol 31 (3) ◽  
pp. 316-331 ◽  
Author(s):  
Nathaniel R. Greene ◽  
Moshe Naveh-Benjamin
Keyword(s):  
Older Adults ◽  
Episodic Memory ◽  
Associative Memory ◽  
Normal Aging ◽  
Associative Recognition ◽  
Specific Information ◽  
Variable Delays ◽  
Age Related ◽  
Multiple Levels

The ability to remember associations among components of an event, which is central to episodic memory, declines with normal aging. In accord with the specificity principle of memory, these declines may occur because associative memory requires retrieval of specific information. Guided by this principle, we endeavored to determine whether ubiquitous age-related deficits in associative memory are restricted to specific representations or extend to the gist of associations. Young and older adults (30 each in Experiment 1, 40 each in Experiment 2) studied face–scene pairs and then performed associative-recognition tests following variable delays. Whereas both young and older adults could retrieve the gist of associations, older adults were impaired in their ability to retrieve more specific representations. Our results also show that associations can be retrieved from multiple levels of specificity, suggesting that episodic memory might be accessed on a continuum of specificity.

scholarly journals Age-related Decline in Associative Memory: Understanding the Roles of Controlled and Automatic Processes

2018 ◽  
Author(s):  
Jimmy Y. Zhong
Keyword(s):  
Older Adults ◽  
Episodic Memory ◽  
Associative Memory ◽  
Automatic Processes ◽  
Memory Decline ◽  
Current Review ◽  
Age Related ◽  
Associative Deficit ◽  
Contextual Elements ◽  
Episodic Memories

Memory decline in old age is highly noticeable based on tasks assessing episodic memory, which require remembering information about events at specific times and places. The exact cognitive mechanism that accounts for this prominent age-related decline in episodic memory has not been well-understood, and the multitude of mechanisms that were proposed have drawn a credible amount of research and discussions. The current review focuses on the associative deficit hypothesis (ADH) - originally proposed by Naveh-Benjamin and colleagues - that was suggested to form the basis of age-related declines in episodic memories. According to the ADH, older adults’ poorer episodic memory is attributed to the difficulties they experience in formulating relations or links between single units of information (i.e., items or contextual elements), binding them together into a coherent distinctive unit, and retrieving the links between the component features/units whenever necessary [COPYRIGHT CC-BY-NC-ND 4.0 J. Y. ZHONG, 2018].

A model to assess age-related changes in two-point discrimination of plantar skin

1999 ◽  
Vol 89 (8) ◽  
pp. 383-391 ◽  
Author(s):  
W Lynch ◽  
J Mooney
Keyword(s):  
Older Adults ◽  
Statistical Analysis ◽  
Linear Relationship ◽  
Middle Aged ◽  
Discrimination Accuracy ◽  
Discrimination Ability ◽  
Fixed Distance ◽  
Age Related ◽  
Older Subjects ◽  
Age Related Changes

A device was constructed to assess two-point discrimination in the plantar skin of younger, middle-aged, and older adults. The device consisted of paired filaments, each delivering a tip force of 4.56 log units (equivalent to 3.63 g), at a fixed distance apart. Statistical analysis showed significant differences in two-point discrimination accuracy between these groups of subjects. Younger subjects showed greater accuracy of plantar two-point discrimination than either middle-aged or older subjects, with an apparent inverse linear relationship between subject age and plantar two-point discrimination ability. A model to assess age-related changes in two-point discrimination is presented.

Episodic Future Thinking and Cognitive Aging

2018 ◽  
Author(s):  
Daniel L. Schacter ◽  
Aleea L. Devitt ◽  
Donna Rose Addis
Keyword(s):  
Older Adults ◽  
Problem Solving ◽  
Episodic Memory ◽  
Prospective Memory ◽  
Cognitive Aging ◽  
Episodic Future Thinking ◽  
Future Thinking ◽  
Age Related ◽  
Prosocial Intentions ◽  
Age Related Changes

Episodic future thinking refers to the ability to imagine or simulate experiences that might occur in an individual’s personal future. It has been known for decades that cognitive aging is associated with declines in episodic memory, and recent research has documented correlated age-related declines in episodic future thinking. Previous research has considered both cognitive and neural mechanisms that are responsible for age-related changes in episodic future thinking, as well as effects of aging on the functions served by episodic future thinking. Studies concerned with mechanism indicate that multiple cognitive mechanisms contribute to changes in episodic future thinking during aging, including episodic memory retrieval, narrative style, and executive processes. Recent studies using an episodic specificity induction—brief training in recollecting episodic details of a recent experience—have proven useful in separating the contributions of episodic retrieval from other non-episodic processes during future thinking tasks in both old and young adults. Neuroimaging studies provide preliminary evidence of a role for age-related changes in default and executive brain networks in episodic future thinking and autobiographical planning. Studies concerned with function have examined age-related effects on the link between episodic future thinking and a variety of processes, including everyday problem-solving, prospective memory, prosocial intentions, and intertemporal choice/delay discounting. The general finding in these studies is for age-related reductions, consistent with the work on mechanisms that consistently reveals reduced episodic detail in older adults when they imagine future events. However, several studies have revealed that episodic simulation nonetheless confers some benefits for tasks tapping adaptive functions in older adults, such as problem-solving, prospective memory, and prosocial intentions, even though age-related deficits on these tasks are not eliminated or reduced by episodic future thinking.

A comparison of immersive virtual reality with traditional neuropsychological measures in the assessment of executive functions

2017 ◽  
Vol 30 (2) ◽  
pp. 79-89 ◽  
Author(s):  
Sophie Melissa Clare Davison ◽  
Catherine Deeprose ◽  
Sylvia Terbeck
Keyword(s):  
Older Adults ◽  
Virtual Reality ◽  
Real World ◽  
Future Research ◽  
Immersive Virtual Reality ◽  
Neuropsychological Measures ◽  
Seating Arrangement ◽  
Age Related ◽  
Initial Work ◽  
Neuropsychological Tasks

ObjectiveThis study investigated immersive virtual reality (IVR), as a novel technique to test executive function of healthy younger and older adults. We predicted IVR tasks to have greater predictive power than traditional measures when assessing age-related cognitive functioning due to the real-world validity of the tasks.MethodsParticipants (n=40) completed the Stroop colour–word test and the trail-making test (TMT) as traditional and commonly used assessments of executive functioning. Participants then completed three IVR tasks; a seating arrangement task, an item location task (both set in a virtual chemistry lab), and a virtual parking simulator.ResultsYounger adults completed significantly more parking simulator levels (p<0.001), placed significantly more objects (p<0.001), and located significantly more items than older adults (p<0.01), demonstrating higher levels of performance. Significant correlations were found between performance on traditional neuropsychological measures and IVR measures. For example, Stroop CW performance significantly correlated with the number of parking simulator levels completed (τ=0.43, p<0.01). This suggests that IVR measures assess the same underlying cognitive constructs as traditional tasks. In addition, IVR measures contributed a significant percentage of the explained variance in age.ConclusionIVR measures (i.e. number of parking simulator levels completed and number of objects placed in the seating arrangement task) were found to be stronger contributors than existing traditional neuropsychological tasks in predicting age-related cognitive decline. Future research should investigate the implementation of these real-world-based tasks in clinical groups given this promising initial work.

scholarly journals Relational binding and holistic retrieval in aging

2020 ◽  
Author(s):  
Chi Ngo ◽  
Nora Newcombe
Keyword(s):  
Older Adults ◽  
Episodic Memory ◽  
Cognitive Aging ◽  
Memory Capacity ◽  
Cognitive Status ◽  
Verbal Iq ◽  
Age Related ◽  
Associative Deficit ◽  
General Cognitive Status ◽  
Relational Binding

Episodic memory binds together diverse elements of an event into a cohesive unit. This property enables the reconstruction of multidimensional experiences when triggered by a cue related to a past event via pattern completion processes. Such holistic retrieval is evident in young adults, as shown by dependency in the retrieval success for different associations from the same event (Horner &amp; Burgess, 2013, 2014). Aspects of episodic memory capacity are vulnerable to aging processes, as shown by reduced abilities to form linkages within an event through relational binding (associative deficit hypothesis: Naveh-Benjamin, 2002). However, prior work has not examined whether this reduction affects holistic retrieval in typical aging. Here, we leveraged dependency analyses to examine whether older adults remember or forget events holistically, and whether the degree of holistic retrieval declines with old age. We found evidence for continued holistic retrieval, because accuracy for one aspect of an event predicted accuracy for other aspects of the same event. Younger and older adults did not differ in the degree of holistic recollection, despite robust age-related differences in relational binding. However, within the group of older adults, holistic recollection showed a significant decline with advancing age, controlling for pairwise relational binding performance, verbal IQ, and general cognitive status. These results suggest that a decline in holistic retrieval is an aspect of episodic memory decrements later in cognitive aging.

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