scholarly journals Orientia beyond fever and rash (Unusual presentations of scrub typhus)

2021 ◽  
Vol 12 (5) ◽  
pp. 130-134
Author(s):  
Avinash Hanbe Rajanna ◽  
Swetha Rajoli
Keyword(s):  
Scrub Typhus ◽  
Leukocytoclastic Vasculitis ◽  
Maculopapular Rash ◽  
Limb Weakness ◽  
Course Of Illness ◽  
Obligate Intracellular ◽  
Lower Limb Weakness ◽  
Male Farmer ◽  
The Family ◽  
Bilateral Lower Limb

Scrub typhus is a zoonotic disease caused by an obligate intracellular gram-negative bacterium of the family Rickettsiaceae called Orientia tsutsugamushi. We are reporting three cases: Case 1:- A 42 year old male, farmer who presented with fever, rash and pandigital gangrene. Case 2:- A 52 year old female positive for scrub typhus treated came with c/o bilateral lower limb weakness which gradually progressed to upper limb, diagnosed to be AIDP, Case 3:- A 32 year old male presented with fever, maculopapular rash and leukocytoclastic vasculitis in first week of illness proved by biopsy. All three cases were positive for OXK (Weil Felix). Scrub typhus can present with unusual clinical features and complication during the course of illness and cases are reported for its varied presentations.

scholarly journals Bilateral lower limb weakness: a cerebrovascular consequence of covid-19 or a complication associated with it?

2020 ◽  
Vol 15 (5) ◽  
pp. 901-905 ◽  
Author(s):  
J. B. Morjaria ◽  
F. Omar ◽  
R. Polosa ◽  
G. Gulli ◽  
P. U. Dalal ◽  
...  
Keyword(s):  
Lower Limb ◽  
Limb Weakness ◽  
Lower Limb Weakness ◽  
Bilateral Lower Limb

scholarly journals Rosuvastatin-related rhabdomyolysis causing severe proximal paraparesis and acute kidney injury

2019 ◽  
Vol 12 (10) ◽  
pp. e229244 ◽  
Author(s):  
Kosar Hussain ◽  
Anil Xavier
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
High Dose ◽  
Normal Range ◽  
Limb Weakness ◽  
Lower Limb Weakness ◽  
History Of ◽  
Complicated Course ◽  
Bilateral Lower Limb ◽  
Initial Blood

We describe the case of a 76-year-old man who presented with bilateral lower limb weakness associated with decreased urine output. His initial blood results showed acute kidney injury (AKI) stage 3 with substantially raised serum creatine kinase concentration of 37 950 IU/L (normal range <171 U/L). He had been on high-dose rosuvastatin for 4 years with a recent brand change occurring 1 week prior to onset of symptoms. There was no history of pre-existing neuromuscular disease. Statin-related rhabdomyolysis was suspected and rosuvastatin was withheld. His muscle strength gradually improved. He required haemodialysis for 10 weeks. He was discharged home after a complicated course of hospitalisation. His renal function improved and he became dialysis-independent; however, he was left with residual chronic kidney disease.

Scrub typhus

2020 ◽  
pp. 1252-1257
Author(s):  
Daniel H. Paris ◽  
Nicholas P.J. Day
Keyword(s):  
Scrub Typhus ◽  
Disease Incidence ◽  
Multiorgan Failure ◽  
Febrile Illness ◽  
Maculopapular Rash ◽  
Obligate Intracellular ◽  
Tsutsugamushi Disease ◽  
Dead End ◽  
Diagnostic Difficulties ◽  
Transstadial Transmission

Orientia spp. are obligate intracellular Gram-negative bacteria that cause scrub typhus, historically known as ‘tsutsugamushi disease’, a febrile illness characterized by early non-specific ‘flu-like’ symptoms, and sometimes a diffuse, macular, or maculopapular rash and/or a necrotic lesion eschar at the inoculation site. Leptotrombidium mites transmit Orientia spp. to humans via the bite of the larval stage, while all mite stages act as bacterial reservoirs through vertical transovarial and transstadial transmission. Scrub typhus is a leading cause of treatable undifferentiated febrile illness in many regions of Asia, and unfortunately remains an underappreciated neglected disease, mainly due to diagnostic difficulties and lack of awareness among medical staff. Complications include meningo-encephalitis, respiratory and renal failure, and severe multiorgan failure. Scrub typhus can be treated effectively with tetracyclines, macrolides, and chloramphenicol. Humans are dead-end hosts and do not participate in the Orientia life cycle, hence treatment does not affect overall disease incidence.

scholarly journals Bilateral lower limb weakness in acute severe ulcerative colitis

The Lancet ◽  
2016 ◽  
Vol 388 (10039) ◽  
pp. 101-102 ◽  
Author(s):  
Ruairi W Lynch ◽  
Timothy Soane ◽  
Rod Gibson ◽  
Suvankar Pal ◽  
Charlie W Lees
Keyword(s):  
Ulcerative Colitis ◽  
Lower Limb ◽  
Limb Weakness ◽  
Severe Ulcerative Colitis ◽  
Lower Limb Weakness ◽  
Bilateral Lower Limb

scholarly journals Primary spinal peripheral primitive neuroectodermal tumor with acute presentation: A case report and review of literature

2019 ◽  
Vol 10 (3) ◽  
pp. 59-61
Author(s):  
Abta Bachchan ◽  
Kaushik Roy ◽  
Suniti Kumar Saha ◽  
Debajyoti Pathak ◽  
Partha Ghosh ◽  
...  
Keyword(s):  
Lower Limb ◽  
Bowel Dysfunction ◽  
Review Of Literature ◽  
Peripheral Primitive Neuroectodermal Tumor ◽  
Thoracic Region ◽  
Radiological Findings ◽  
Limb Weakness ◽  
Lower Limb Weakness ◽  
Neuroectodermal Tumors ◽  
Bilateral Lower Limb

Primary spinal primitive neuroectodermal tumors (PNET) is a rare occurrence and carries a poor prognosis. A 13-year old female patient acutely presented with pain in the thoracic region, bilateral lower limb weakness, bladder and bowel dysfunction. Clinically paraplegia with truncal weakness, lower limb deep tendon reflexes of both side were absent and planter reflexes equivocal bilaterally. Preoperative MRI of thoracic spine revealed D4-D6 extradural SOL. A D4-D5 Laminectomy and left Cortico transversectomy done. Pathological findings were consistent with PNET. The clinical, histopathological, and radiological findings of the patient are presented.

scholarly journals Immediate Response to Chemotherapy in an Adult Neuroblastoma Patient Presenting with Cord Compression

2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Nedal Bukhari ◽  
Bachar Harfouch ◽  
Majid Shallal Alotaibi ◽  
Hulayel Al-Harbi ◽  
Omar Chamdine
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Cord Compression ◽  
Limb Weakness ◽  
Lower Limb Weakness ◽  
Response To Chemotherapy ◽  
History Of ◽  
Bilateral Lower Limb ◽  
The Right ◽  
Neuroblastoma Patient

We report a case of a 31-year-old female patient with high-risk neuroblastoma (NBL) who presented with a history of static back pain and bilateral lower limb weakness for almost a month. Her primary tumor was located in the right paraspinal region, causing spinal cord compression (SCC). Chemotherapy was administered with an immediate clinical improvement noted after 24 hours of starting treatment. We herein report the efficacy of chemotherapy in an adult neuroblastoma (aNBL) patient presenting with spinal cord compression.

scholarly journals Neurological deficit following spinal anaesthesia for caesarean section: an anesthetist’s nightmare

2017 ◽  
Vol 5 (2) ◽  
pp. 694
Author(s):  
Unnati Asthana ◽  
Deepika Aggarwal ◽  
Jai Prakash ◽  
Madhu Gupta ◽  
Anshu Mali
Keyword(s):  
Caesarean Section ◽  
Spinal Anaesthesia ◽  
Cauda Equina ◽  
Emergency Caesarean Section ◽  
Past Medical History ◽  
Limb Weakness ◽  
The Third ◽  
Lower Limb Weakness ◽  
Bilateral Lower Limb ◽  
Intraspinal Hematoma

Neurological deterioration after regional anaesthesia, though extremely rare has been reported worldwide. A number of mechanisms like intraspinal hematoma, meningitis, cauda equina syndrome, etc. have been attributed to this dreadful complication. We present a case of a 26 year old female with no past medical history who was posted for emergency caesarean section. After an uneventful surgery under a subarachnoid block, the patient was discharged on the third day. However, on tenth postoperative day, the patient presented in casualty with bilateral lower limb weakness and backache. What was initially thought of being a rare post-operative complication of spinal anaesthesia was found to be an incidental intradural lesion on subsequent evaluation. Even a thorough pre-anaesthetic checkup may not prevent the occurrence of such incidents postoperatively.

Sign in / Sign up

Export Citation Format

Share Document