scholarly journals Association of diabetes mellitus and high myopia in primary open angle glaucoma

1970 ◽  
Vol 10 (1) ◽  
pp. 35-39
Author(s):  
S Bhattarai ◽  
K Sapkota ◽  
SMN Prabhudesai ◽  
JK Shrestha ◽  
AK Sharma
Keyword(s):  
Diabetes Mellitus ◽  
High Myopia ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Cross Sectional Study ◽  
Significant Loss ◽  
Open Angle ◽  
Cross Sectional ◽  
Study Association ◽  
Diagnosis Of Diabetes Mellitus

Background: Primary open angle glaucoma (POAG), a chronic, slowly progressive, optic neuropathy, is insidious in onset and painless, until it has caused a significant loss of vision and visual field. Diabetes mellitus and high myopia are the major risk factor of POAG. Objectives: To determine correlation of diabetes mellitus and high myopia in POAG and to estimate the duration of onset of POAG from the diagnosis of diabetes mellitus and high myopia. Method: This retrospective and cross sectional study was conducted in Prabhudesai eye clinic, Pune, India. All the patients diagnosed as POAG from 1st September 2008 to 1st March 2009 AD were included in this study. Association of high myopia with diabetes mellitus was determined by SPSS 13 software. The average duration of onset of POAG after the diagnosis of diabetes mellitus and high myopia was calculated. Results: There were 63.3% (38) male and 36.7% (22) female out of 60 patients of POAG with mean age 54.4±15.4 years. Among them, 27 (45.0%) patients had diabetes mellitus or high myopia. Onset of POAG was found to occur after 11.1±8.3 years of the diagnosis of diabetes and 10.6±3.2 years after the diagnosis of high myopia. Conclusion: The incidence of diabetes mellitus and high myopia was high and significantly associated in primary open angle glaucoma. POAG was detected soon after the onset of diabetes mellitus and high myopia. DOI: http://dx.doi.org/10.3126/hren.v10i1.6005 HREN 2012; 10(1): 35-39

scholarly journals Gait parameters, functional mobility and fall risk in individuals with early to moderate primary open angle glaucoma: a cross-sectional study

2018 ◽  
Vol 22 (5) ◽  
pp. 376-382 ◽  
Author(s):  
Henrique de Alencar Gomes ◽  
Bruno de Souza Moreira ◽  
Rosana Ferreira Sampaio ◽  
Sheyla Rossana Cavalcanti Furtado ◽  
Sebastião Cronemberger ◽  
...  
Keyword(s):  
Fall Risk ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Cross Sectional Study ◽  
Functional Mobility ◽  
Open Angle ◽  
Sectional Study ◽  
Cross Sectional ◽  
Gait Parameters

scholarly journals Circadian Variation of Ocular Perfusion Pressure in Primary Open Angle Glaucoma- A Cross-sectional Study

2021 ◽  
Author(s):  
Raheeba Pakeer Muhammed ◽  
Neeta Sidhan ◽  
Beena Thankappan
Keyword(s):  
Primary Open Angle Glaucoma ◽  
Perfusion Pressure ◽  
Open Angle Glaucoma ◽  
Circadian Variation ◽  
Cross Sectional Study ◽  
Open Angle ◽  
Sectional Study ◽  
Ocular Perfusion Pressure ◽  
Cross Sectional ◽  
Ocular Perfusion

Introduction: Various haemodynamic factors have been implicated as pathophysiological mechanisms in Primary Open Angle Glaucoma (POAG) other than raised Intraocular Pressure (IOP). However, the exact relationship still remains unclear. Aim: To examine the circadian pattern of Blood Pressure (BP), IOP and Ocular Perfusion Pressure (OPP) with the aim of understanding their relationships in a cohort of patients with POAG. Materials and Methods: A cross-sectional study was conducted in which 44 cases of newly diagnosed, non-hypertensive patients with POAG were enrolled and categorised based on the severity of glaucoma. Recording of BP and IOP were done every 4th hourly during a 24 hour hospital stay. The Mean OPP (MOPP) was calculated as 2/3×Mean Arterial Pressure (MAP)-IOP. Systolic OPP (SOPP) was calculated as Systolic BP-IOP and Diastolic OPP (DOPP) was calculated as Diastolic BP-IOP. The diurnal, nocturnal and 24 hour fluctuations were derived from the difference between the highest and lowest values within each period. Data was analysed using Statistical Package for the Social Sciences (SPSS) version 16.0. Univariate and multivariate regression analysis of the variables with age and severity of POAG were performed Results: Significant positive correlation of the nocturnal fluctuations in MAP (r=0.533), SOPP (r=0.835), DOPP (r =0.768), MOPP (r=0.685) and 24 hour fluctuation in MOPP (r=0.636) were noted with severity of glaucoma on multivariate analysis. No significant correlation of these parameters with age was noted on multivariate analyses. Conclusion: Nocturnal dip in OPP was an important observation among patients with POAG, potentially contributing to its pathophysiology.

scholarly journals A CROSS-SECTIONAL STUDY TO EVALUATE THE USEFULNESS OF ‘PRESSURE TO CORNEA INDEX’ IN PREDICTION OF PRIMARY OPEN ANGLE GLAUCOMA

2018 ◽  
Vol 7 (01) ◽  
pp. 47-49
Author(s):  
Pandiyaraj Saravanasankar ◽  
Anbazhaghan Amudha ◽  
Srinivasan Muralikrishnan ◽  
Reethysreekumar Sruthi ◽  
Rajan Saranya ◽  
...  
Keyword(s):  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Cross Sectional Study ◽  
Open Angle ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Diabetes Mellitus and the risk of Primary open angle glaucoma

2017 ◽  
Vol 9 (1) ◽  
pp. 17-23 ◽  
Author(s):  
P Lavaju ◽  
S Shah ◽  
S Sharma ◽  
R Maskey
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factor ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Corneal Thickness ◽  
Open Angle ◽  
Cross Sectional ◽  
Female Ratio ◽  
Group I ◽  
Group Ii

Background: Diabetes mellitus (DM) is one of the risk factors for Primary open angle glaucoma (POAG). Inclusion of DM as a risk factor for POAG is controversial. The objectives of the study were to investigate whether Type II (T2) DM is a risk factor for POAG and to determine central corneal thickness (CCT) in the subjects with T2DM and to examine the relationship between T2DM and intraocular pressure (IOP).Materials and methods: A comparative cross sectional study was conducted including 189 subjects of age > 40 years. In Group I, 113 patients diagnosed with T2DM and Group II, age and sex matched 76 subjects with POAG without DM was included. Detailed ocular examination, IOP, CCT and funduscopy evaluation was done. Results: Most of the patients were more than 60 years of age with mean age 58 ± 11 years. Male: female ratio was 1:1. POAG was seen in 27.4% of patients with T2DM. Mean IOP in T2DM was 14.67± 2.63mmHg and in non diabetic, 17.25±4.47 mmHg (p <0.00). In group I, mean CCT was 538.83± 22.7μm and in group II, 531.26 ± 20.9μm (p-0.126). There was no association between CCT and glaucoma (p=0.072, 95% CI: -0.76 –17.46). The study could not elicit an association of T2DM with glaucoma. Duration of T2DM did not affect an association between T2DM and glaucoma (p-0.757). Random blood sugar (p<0.001) and oral hypoglycemic drugs (p=0.030) showed an association with glaucoma. Conclusion: The study failed to show an association between T2DM and primary open angle glaucoma and CCT though an association seen with IOP. A larger prospective comparative study may be help in understanding this association. 

scholarly journals A study of relation between primary open angle glaucoma and type II diabetes mellitus

2018 ◽  
Vol 6 (3) ◽  
pp. 997 ◽  
Author(s):  
Aditya Desai ◽  
Dipak Patel ◽  
Avani Sapovadia ◽  
Parin Mehta ◽  
Jyotindra Brahmbhatt
Keyword(s):  
Diabetes Mellitus ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Positive Family History ◽  
Type Ii Diabetes Mellitus ◽  
P Value ◽  
Open Angle ◽  
Exclusion Criteria ◽  
Cross Sectional ◽  
Control Study

Background: Primary open angle glaucoma has been characterized by its adult onset, IOP >21mmHg at some point in the course of the disease, open angles on gonioscopy, glaucomatous visual field changes and glaucomatous optic nerve damage. POAG is a multi-factorial disease such as age, black race, positive family history, high myopia etc. Diabetes mellitus has also been considered as one of the risk factors, but no major study has been conducted to provide tangible proof.Methods: This cross sectional, case control study was conducted to determine whether diabetes stands as a risk factor in development of glaucoma. The selected patients were divided into 3 groups based on inclusion and exclusion criteria. They were subjected to complete ocular examination including gonioscopy and perimetry.Results: The 16 patients from 50 of the diabetic group (28%) were found to have POAG. The p value was <0.005 which was statistically significant. Also, no correlation was found between blood sugar and IOP levels in these patients.Conclusions: These data show a significant correlation between diabetes and glaucoma. Further studies are warranted to determine its actual role in pathogenesis of glaucoma.

Sign in / Sign up

Export Citation Format

Share Document