Cellular Alteration of the Oral Mucosa due to Orthodontic Appliances and Tobacco Smoking: A Cytomorphometric Study

2019 ◽  
Vol 15 (3) ◽  
pp. 206-210
Author(s):  
Vinay Marla ◽  
Dharanidhar Baral ◽  
Prabhat Ranjan Pokharel ◽  
Ashish Shrestha ◽  
Rajesh Gyawali ◽  
...  
Keyword(s):  
Oral Mucosa ◽  
Tobacco Smoking ◽  
Orthodontic Treatment ◽  
Study Groups ◽  
Cell Diameter ◽  
Orthodontic Appliances ◽  
Low Grade ◽  
Nuclear Area ◽  
Mucosal Cells ◽  
Orthodontic Patients

Introduction: Fixed orthodontic treatment causes chronic low grade irritation on the oral mucosa. Tobacco smoking is considered to be a risk factor in the development of oral cancer. This study involves a cytomorphometric analysis on the buccal mucosal cells in patients undergoing fixed orthodontic treatment who are tobacco smokers. Methods: Exfoliated buccal mucosal cells were obtained from orthodontic patients (smokers & non-smokers) as well as smokers and non-smokers who are not undergoing any orthodontic treatment. Smears were stained with rapid PAP stain and digital images of 50 cells were analysed using the Image J software. Results: Statistical analysis revealed that there were significant increase in the values of nuclear and cell diameter between non-smokers undergoing orthodontic treatment and smokers (p<0.001 & p=0.014 respectively), and between non-smokers undergoing orthodontic treatment and smokers undergoing orthodontic treatment (p<0.001 & p=0.015 respectively). Also, nuclear area and cell area showed significant differences between many of the study groups. Conclusion: It can be concluded that there are nuclear and cellular alterations in patients undergoing fixed orthodontic treatment who are smokers

scholarly journals CELLULAR ALTERATIONS OF THE ORAL MUCOSA DUE TO ORTHODONTIC APPLIANCES AND TOBACCO SMOKING: A CYTOMORPHOMETRIC STUDY

2018 ◽  
Vol 14 (2) ◽  
Author(s):  
Vinay Marla ◽  
Varun Pratap Singh ◽  
Dharanidhar Baral ◽  
Prabhat Ranjan Pokharel ◽  
Ashish Shrestha ◽  
...  
Keyword(s):  
Oral Mucosa ◽  
Tobacco Smoking ◽  
Orthodontic Treatment ◽  
Study Groups ◽  
Cell Diameter ◽  
Orthodontic Appliances ◽  
Low Grade ◽  
Mucosal Cells ◽  
Orthodontic Patients ◽  
Cellular Alterations

<p><strong>Introduction</strong>: Fixed orthodontic treatment causes chronic low grade irritation on the oral mucosa. Tobacco smoking is considered to be a risk factor in the development of oral cancer. This study was designed to do a cytomorphometric analysis on the buccal mucosal cells in patients undergoing fixed orthodontic treatment who are tobacco smokers.</p><p><strong>Methods</strong>: Exfoliated buccal mucosal cells were obtained from orthodontic patients (smokers &amp; non-smokers) as well as smokers and non-smokers who are not undergoing any orthodontic treatment. Smears were stained with rapid PAP stain and digital images of 50 cells were analysed using the Image J software.</p><p><strong>Results and conclusion</strong>: Statistical analysis revealed that there were significant increase in the values of nuclear and cell diameter between non-smokers undergoing orthodontic treatment and smokers (p&lt;0.001 &amp; p=0.014 respectively), and between non-smokers undergoing orthodontic treatment and smokers undergoing orthodontic treatment (p&lt;0.001 &amp; p=0.015 respectively). Also, nuclear area and cell showed significant differences between many of the study groups. Based on these results, it can be concluded that there are nuclear and cellular alterations in patients undergoing fixed orthodontic treatment who are smokers. <strong></strong></p>

scholarly journals Effect of fixed orthodontic appliances on nonmicrobial salivary parameters

2018 ◽  
Vol 88 (6) ◽  
pp. 806-811 ◽  
Author(s):  
Ioannis P. Zogakis ◽  
Erez Koren ◽  
Shlomit Gorelik ◽  
Isaac Ginsburg ◽  
Miriam Shalish
Keyword(s):  
Orthodontic Treatment ◽  
Statistical Significance ◽  
Orthodontic Appliances ◽  
Inclusion Criteria ◽  
Reactive Protein ◽  
Fixed Orthodontic Appliances ◽  
Salivary Ph ◽  
Orthodontic Patients ◽  
The Difference ◽  
Ph Decrease

ABSTRACT Objectives: To examine possible changes in the levels of salivary antioxidants, C-reactive protein (CRP), cortisol, pH, proteins, and blood in patients treated with fixed orthodontic appliances. Materials and Methods: Salivary samples from 21 orthodontic patients who met specific inclusion criteria were collected before the beginning of orthodontic treatment (T0; baseline), 1 hour after bonding (T1), and 4–6 weeks after bonding (T2). Oxidant-scavenging ability (OSA) was quantified using a luminol-dependent chemiluminescence assay. Cortisol and CRP levels were measured using immunoassay kits. pH levels and presence of proteins and blood in the samples were quantified using strip-based tests. Results: A significant decrease in salivary pH was observed after bonding (P = .013). An increase in oxidant-scavenging abilities during orthodontic treatment was detected, but the change was not statistically significant. Cortisol and CRP levels slightly increased after bonding, but the difference was small without statistical significance. Changes in the presence of proteins and blood were also insignificant. Conclusions: Exposure to fixed orthodontic appliances did not show a significant effect on salivary parameters related to inflammation or stress, with the exception of a significant but transient pH decrease after bonding.

scholarly journals Pain, masticatory performance and swallowing threshold in orthodontic patients

2013 ◽  
Vol 18 (6) ◽  
pp. 117-123 ◽  
Author(s):  
Marcos Porto Trein ◽  
Karina Santos Mundstock ◽  
Leonardo Maciel ◽  
Jaqueline Rachor ◽  
Gustavo Hauber Gameiro
Keyword(s):  
Particle Size ◽  
Orthodontic Treatment ◽  
Orthodontic Appliances ◽  
Masticatory Performance ◽  
Threshold Test ◽  
Orthodontic Patients ◽  
Median Particle ◽  
Fixed Appliances ◽  
Baseline Values ◽  
Individual Capacity

OBJECTIVE: The aim of this study was to assess pain, masticatory performance and swallowing threshold of patients undergoing orthodontic treatment. METHODS: Ten patients of both genders (mean age of 17.25 ± 5.21 years), with complete permanent dentition, who underwent orthodontic treatment with fixed appliances were evaluated. The masticatory performance and the swallowing threshold were assessed by patient's individual capacity of fragmenting an artificial test food (Optocal) which was chewed and had the resulting particles processed by a standardized sieving method, presenting the median particle size (MPS) of crushed units. The intensity of pain / discomfort during chewing was evaluated by means of a visual analog scale. All tests were performed at the following times: T0 - before activating the orthodontic appliance; T1 - 24 hours after activation, and T2 - 30 days after activation. RESULTS: The results showed a significant increase in pain at T1 (T0 - 0.60 ± 0.70 mm; T1 - 66.2 ± 34.5 mm), returning to baseline values at T2 (3.20 ± 3.82 mm). Masticatory performance was also reduced in T1 (MPS 10.15 ± 1.1 mm²) in comparison to T0 (MPS 7.01 ± 2.9 mm²) and T2 (MPS 6.76 ± 1.3 mm²). However, particle size was not affected in the swallowing threshold test (T0 - 5.47 ± 2.37 mm²; T1 - 6.19 ± 2.05 mm²; T2 - 5.94 ± 2.36 mm²). CONCLUSION: The orthodontic appliances did not interfere in the size of the particles that would be swallowed, even in the presence of pain.

scholarly journals Microbiological Evaluation of 0.2% Chlorhexidine Gluconate Mouth Rinse in Orthodontic Patients

2007 ◽  
Vol 77 (5) ◽  
pp. 881-884 ◽  
Author(s):  
Emel Sari ◽  
Ilhan Birinci
Keyword(s):  
Streptococcus Mutans ◽  
Orthodontic Treatment ◽  
Chlorhexidine Gluconate ◽  
Wilcoxon Test ◽  
Orthodontic Appliances ◽  
Mouth Rinse ◽  
Fixed Orthodontic Appliances ◽  
Orthodontic Patients ◽  
Fixed Appliances

Abstract Objective: To assess the effectiveness of 0.2% chlorhexidine gluconate mouth rinse on Streptococcus mutans and lactobacilli in orthodontic patients with fixed appliances. Materials and Methods: Twenty patients, aged 13–18, with fixed orthodontic appliances participated in the study. The levels of S mutans and lactobacilli in saliva samples were evaluated at four stages: at the beginning of the orthodontic treatment, at least 2 weeks after the bonding of brackets, 1 week after the introduction of 0.2% chlorhexidine gluconate mouth rinse, and at the fourth week. The changes in S mutans and lactobacilli levels were analyzed via Wilcoxon test. Results: Increases in bacterial levels of S mutans and lactobacilli were detected after the orthodontic appliances were bonded. A significant decrease in S mutans levels was observed 1 week after the introduction of chlorhexidine mouth rinse. Conclusions: An 0.2% chlorhexidine gluconate mouth rinse decreased S mutans levels, but had no effect on lactobacilli levels.

The effectiveness of a dental gel with barberry extract in the treatment of plaque-induced gingivitis in orthodontic patients undergoing treatment with fixed appliances

2021 ◽  
Vol 21 (1) ◽  
pp. 51-56
Author(s):  
A. G. Skubitskaya ◽  
I. V. Firsova ◽  
S. V. Poroyskyi ◽  
O. G. Strusovskaya
Keyword(s):  
Orthodontic Treatment ◽  
Periodontal Diseases ◽  
Orthodontic Appliances ◽  
Local Immunity ◽  
Group I ◽  
Fixed Orthodontic Appliances ◽  
Tnf Α ◽  
Orthodontic Patients ◽  
Fixed Appliances ◽  
Group Ii

Relevance. The high necessity in orthodontic treatment among young patients and the use of fixed orthodontic appliances for the treatment of dental pathology are the factors that initiate inflammatory periodontal processes. Timely diagnosis and optimal preventive and treatment procedures can prevent or stop the inflammatory periodontal complications which could have developed during the orthodontic treatment. One of the effective methods for the prevention and treatment of inflammatory periodontal diseases is the use of targeted antimicrobial agents based on medicinal plants that have specific antimicrobial activity against periodontal pathogens. Purpose – to study the effectiveness of the dental gel with barberry extract for the treatment of plaque-induced gingivitis in orthodontic patients during the active phase of the treatment with fixed appliances.Materials and methods. The study included 60 patients (35 women and 25 men) aged 18 to 35 years who had presented for the orthodontic care. The patients undergoing orthodontic treatment with fixed appliances were randomly divided into two groups. In group I, the patients were prescribed applications of a dental gel with barberry extract; in group II, this medication was not prescribed. The clinical condition of the periodontium was assessed with periodontal indices PMA, SBI and OHI-S. The immune status was evaluated by the level of secretory IgA, interleukins (IL-1β and IL-4) and tumor necrosis factor-α (TNF-α). The patients were followed up during 1 month of treatment. The results were statistically processed with Statsoft Statistica 8.0 and Graph Pad Prism 5.0.Results. In group II, the production of immunoglobulin IgA, pro- and anti-inflammatory cytokines was impaired after a month of treatment, associated with a significant deterioration in the oral hygiene status and an increase in PMA (by 3 times), SBI (by 5.3 times) indices. In group II, the oral fluid concentrations of IL-1β, IL-4 and TNF-α significantly differed from those in group I as of the 7th day of the observation period and indicated suppression of the mucosal immunity. Clinical and immune parameters of the group I patients improved and were comparable with the control by the end of the observation month.Conclusions. Patients with dental abnormalities are at risk of developing inflammatory periodontal diseases. The results of the immunological tests, performed during the treatment with the use of a dental gel with barberry extract, demonstrated the recovery of the local immunity, as evidenced by the elevation of secretory immunoglobulin A in saliva and improvement of cytokine profile parameters.

scholarly journals Periodontal health knowledge and awareness among subjects with fixed orthodontic appliance

2018 ◽  
Vol 23 (5) ◽  
pp. 40.e1-40.e9 ◽  
Author(s):  
Elham S. Abu Alhaija ◽  
Eman M. Al-Saif ◽  
Dafi Q. Taani
Keyword(s):  
Orthodontic Treatment ◽  
Health Knowledge ◽  
Negative Attitude ◽  
Gingival Recession ◽  
Orthodontic Appliances ◽  
Duration Of Treatment ◽  
Periodontal Health ◽  
Fixed Orthodontic Appliances ◽  
Orthodontic Patients ◽  
High Level

Abstract Objective: To report on periodontal health knowledge and awareness among orthodontic patients and to investigate the effect of age, attitude and duration of orthodontic treatment on periodontal health awareness among orthodontic patients. Methods: A total of 297 orthodontics patient (90 males, 207 females) with mean age of 17.7 ± 5.0 years (older then 18 years = 119, 18 years or younger = 178) were included in this study. Subjects were currently wearing upper and lower fixed orthodontic appliances for an mean period of 12.55 ± 10.86 months (less than or equal to 18 months = 231, more than 18 months = 66). Data was collected through a self-administered questionnaire (demographic characteristics, subjects’ awareness toward their periodontal health, periodontal knowledge among orthodontic patient and patients’ attitude toward orthodontic treatment regarding periodontal health) and clinical periodontal examination. Results: Periodontal knowledge was poor among orthodontic patients in relation to dental plaque. Only 24 subjects (8%) correctly answered knowledge-related questions. Adult orthodontic patients reported negative attitude toward fixed orthodontic treatment in respect to periodontal health (p<0.001). Duration of orthodontic treatment negatively affected subjects’ attitude toward fixed orthodontic treatment (p<0.01). The majority of subjects were in the high level of awareness group (64%). Orthodontic patients’ awareness toward their periodontal health during fixed orthodontic treatment was affected by attitude scores (p=0.005), number of teeth with gingival recession (p=0.041), Gingival Index (p=0.000), duration of treatment (p=0.047) and age (p=0.008). Conclusions: Periodontal health knowledge among orthodontic patients was poor. Orthodontic patients’ awareness of their periodontal health was moderate and was affected by age, attitude and duration of orthodontic treatment.

An Investigation into Factors Influencing the Amount of Orthodontic Treatment Attempted by the Recent Graduates of Two Dental Schools

1982 ◽  
Vol 9 (2) ◽  
pp. 77-83 ◽  
Author(s):  
I. D. Brown ◽  
C. D. Stephens ◽  
L. A. Usiskin
Keyword(s):  
Orthodontic Treatment ◽  
Orthodontic Appliances ◽  
Dental Practice ◽  
Factors Influencing ◽  
General Dental Practice ◽  
Orthodontic Patients ◽  
Recent Graduates ◽  
Dental Schools

A questionnaire was sent to Bristol and Guy's Dental Graduates who had been qualified for between 3 and 5 years. This showed that three-quarters of those who were currently in general dental practice had treated six or more orthodontic patients since qualification. A fifth claimed to have treated more than 45. An important factor in determining whether a practitioner carries out orthodontic treatment himself, or refers Patients to a specialist, is the confidence he has in his own ability to adjust and monitor orthodontic appliances. The convenience of alternative orthodontic services would appear to have no influence in such decisions.

scholarly journals Salivary microbial changes during the first 6 months of orthodontic treatment

PeerJ ◽  
2020 ◽  
Vol 8 ◽  
pp. e10446
Author(s):  
Mei Zhao ◽  
Min Liu ◽  
Wei Chen ◽  
Haiping Zhang ◽  
Yuxing Bai ◽  
...  
Keyword(s):  
Orthodontic Treatment ◽  
High Throughput Sequencing ◽  
Oral Microbiome ◽  
Orthodontic Appliances ◽  
Rrna Gene ◽  
Operational Taxonomic Units ◽  
Orthodontic Patients ◽  
Oral Hygiene Instructions ◽  
The 16S Rrna Gene ◽  
Dynamic Alteration

Background Orthodontic treatment is widely used to treat malocclusion. However, the influence of treatment on the oral microbiome remains unclear. In this study, we investigated salivary microbial changes in patients undergoing orthodontic treatment. Methods In total, 19 orthodontic patients participated in this study. Saliva samples were collected at the following three timepoints: before (T0) and 3 months (T1) and 6 months (T2) after the placement of orthodontic appliances. High-throughput sequencing was performed based on the 16S rRNA gene V4 region. Results The phyla of Proteobacteria, Bacteroidetes, Firmicutes, Actinobacteria and Fusobacteria were predominant. Observed Species, Chao1 and ACE, which represent α diversity, were significantly decreased at T1 and subsequently increased at T2. In addition, the β diversity at T1 based on the Bray-Curtis distances differed from T0 and T2. The relative abundances of Prevotella, Porphyromonas and Peptostreptococcus were decreased with treatment, whereas those of Capnocytophaga and Neisseria exhibited the opposite results. In total, 385 of 410 operational taxonomic units were shared at T0, T1 and T2. The co-occurrence networks with hub nodes at T1 were the most complex. Conclusion Orthodontic treatment temporarily affected the saliva microbial community. This dynamic alteration in species did not induce deterioration in oral health. Oral hygiene instructions were necessary and should be emphasized during each visit. Further studies with longer observation periods and more participants are required.

scholarly journals Self-Reported Changes in Oral Hygiene Habits among Adolescents Receiving Orthodontic Treatment

2019 ◽  
Vol 7 (4) ◽  
pp. 96 ◽  
Author(s):  
Sandra Petrauskiene ◽  
Natalia Wanczewska ◽  
Egle Slabsinskiene ◽  
Gintare Zemgulyte
Keyword(s):  
Oral Hygiene ◽  
Orthodontic Treatment ◽  
Background Information ◽  
Categorical Variables ◽  
Orthodontic Appliances ◽  
Risk Indicator ◽  
Fixed Orthodontic Appliances ◽  
Significant Difference ◽  
Orthodontic Patients ◽  
Oral Hygiene Habits

The prevalence of malocclusion and a need for orthodontic treatment is high. Orthodontic appliances increase biofilm accumulation by expanding plaque retention sites. The aim of this study was to investigate the self-reported changes in oral hygiene habits among adolescents receiving orthodontic treatment. A cross-sectional study of 291 patients aged 10–17 years (mean (M) = 12.98; standard deviation (SD) = 2.36) was conducted in the Department of Orthodontics, Lithuanian University of Medical Sciences (LSMU) Hospital (Kaunas, Lithuania) during the fall semester (October–January) of the 2017/2018 study year. An anonymous self-administered questionnaire covered background information, experience of orthodontic treatment, oral hygiene habits and the seeking of professional dental care. Statistical data analysis was performed using SPSS version 22. To establish relationships between categorical variables, Chi-squared tests (χ2) were used. A p-value ≤ 0.05 was set to indicate statistically significant difference. The univariate logistic regression analysis evaluated the probability of an event given a certain risk indicator, including odds ratio (OR) and its confidence interval (95% CI). Associations were found between the usage of auxiliary measures (OR = 1.797 (1.118–2.887), p = 0.015), tongue cleaning (OR = 1.712 (1.059–2.767), p = 0.028), mouth rinsing after meals (OR = 1.707 (1.048–2.781), p = 0.032) and experience of orthodontic treatment, respectively. More orthodontic patients underwent professional oral hygiene regularly than non-orthodontic patients (p = 0.024). More patients with fixed orthodontic appliances reported significantly changed oral hygiene habits, while more orthodontic patients with removable appliances did not change their oral hygiene habits.

Oral Hygiene Status among Orthodontic Patients

2010 ◽  
Vol 11 (4) ◽  
pp. 25-32 ◽  
Author(s):  
Fatin Awartani ◽  
Farhad Atassi
Keyword(s):  
Home Care ◽  
Oral Hygiene ◽  
Orthodontic Treatment ◽  
Plaque Index ◽  
Orthodontic Appliances ◽  
Dental Hygienist ◽  
Maintenance Program ◽  
Fixed Orthodontic Appliances ◽  
Significant Difference ◽  
Orthodontic Patients

Abstract Aim The aim of this study was to evaluate the oral hygiene status of patients with fixed orthodontic appliances. Methods and Materials The following indices were used to evaluate the oral hygiene status of patients in orthodontic treatment: gingival bleeding index (GBI), plaque index (PI), and ortho-plaque index (OPI). A self-administrated questionnaire was prepared covering oral hygiene practice, oral hygiene cleaning aids, and number of visits to a dental hygienist. Results Fifty patients (15–30 years old) were selected for the study from among the orthodontic patients treated at the King Saud University College of Dentistry, Riyadh, Saudi Arabia. Results showed that the PI and OPI were high with mean scores of 65.24 (SD 16.43) and 53.56 (SD 8.74) respectively, while the average GBI was a much lower value at 19.14 (SD 7.95). No significant difference was observed between male and female patients for the PI (p=0.925) and for the OPI (p=0.072), but a significant difference was observed for the GBI at the 5 percent significance level (p=0.033). The result of OPI showed that 20 (40 percent) of the patients had fair oral hygiene, whereas 30 (60 percent) had poor oral hygiene. Only 16 (32 percent) of the participants reported visiting the dental hygienist during their orthodontic treatment, while the remaining 34 (68 percent) did not. Conclusion The oral home care of the orthodontic patients surveyed was not at an optimal level, which indicated the need to establish an oral hygiene maintenance program. Clinical Significance Inadequate oral home care among orthodontic patients may make them more prone to develop gingivitis during orthodontic treatment. It is, therefore, essential that oral hygiene instructions and a hygiene maintenance program not be overlooked during orthodontic treatment. Citation Atassi F, Awartani F. Oral Hygiene Status among Orthodontic Patients. J Contemp Dent Pract [Internet]. 2010 July; 11(4):025-032. Available from: http://www.thejcdp.com/journal/ view/volume11-issue4-atassi

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