scholarly journals Glomus tumor of uncertain malignant potential

1970 ◽  
Vol 1 (1) ◽  
pp. 66-68
Author(s):  
R Baral ◽  
H Limbu
Keyword(s):  
Glomus Tumor ◽  
Subcutaneous Tissue ◽  
Malignant Potential ◽  
Merkel Cell ◽  
Uncertain Malignant Potential ◽  
Glomus Tumors ◽  
Nail Bed ◽  
Current Definition ◽  
History Of ◽  
Glomus Body

Glomus tumors closely resemble the normal glomus body and have a predilection for skin and subcutaneous tissue. Clinically, Glomus tumors are present on the nail bed and are of less than 1 cm. We report a case of a male who presented with a 3 month history of swelling in the left thumb which was mildly tender. The swelling measured 6 x 6.5 cm. On microscopy the tumor showed mild atypia with increased mitotic activity. These features, by current definition, would suggest uncertain malignant potential. Keywords: Glomus tumor; Glomangioma; Merkel cell carcinoma.DOI: 10.3126/jpn.v1i1.4457 Journal of Pathology of Nepal (2011) Vol.1, 66-68  

scholarly journals Low-Grade Malignancy Glomus Tumor in a Setting of Multiple Glomus Tumors – Case Report

2019 ◽  
Vol 7 (23) ◽  
pp. 4082-4088
Author(s):  
Violeta Vasilevska-Nikodinovska ◽  
Milan Samardjiski ◽  
Rubens Jovanovik ◽  
Boro Ilievski ◽  
Vesna Janevska
Keyword(s):  
Glomus Tumor ◽  
Subcutaneous Tissue ◽  
Vena Cava ◽  
Malignant Potential ◽  
Biological Behavior ◽  
Low Grade ◽  
Uncertain Malignant Potential ◽  
Glomus Tumors ◽  
Small Nodule ◽  
Multiple Lesions

BACKGROUND: Glomus tumors are rare neoplasms accounting for less than 2% of all soft tissue tumors but multiple lesions may be seen in up to 10% of the patients. Solitary glomus tumor (GT) most frequently appears as small nodule in specific locations such as subungual region or deep dermis. However, rarely these entities have been observed in extracutaneous locations such as the gastrointestinal, cardiovascular, respiratory tracts, and other visceral organs. A small fraction of the GTs may present as tumors of uncertain malignant potential or as malignant glomus tumors. CASE PRESENTATION: We report a patient with multiple glomus tumors on the time of diagnosis, which was histologically diagnosed as an atypical glomus tumor following resection of a tumor thrombus in the left renal vein, inferior vena cava trombus with intracardial extension, and mitral valve specimen. The intramuscular lesion from the thigh was diagnosed as a glomus tumor of uncertain malignant potential. Further examinations revealed multiple lesions trough her body: kidneys, breast, heart and subcutaneous tissue. The diagnosis of glomus tumor of uncertain malignant potential versus glomus tumor with low malignant potential could be quite challenging, and the clinical course may be as a determining factor for final diagnosis. CONCLUSION: To our knowledge, this is the only known case of glomus tumor with multiple organ involvement and aggressive biological behavior at presentation.

scholarly journals Glomus tumor: an atypical presentation

2020 ◽  
Vol 6 (2) ◽  
pp. 269
Author(s):  
Rajeshwari K. A. ◽  
Rajagopal R.
Keyword(s):  
Glomus Tumor ◽  
Malignant Potential ◽  
Glomus Tumour ◽  
Excision Biopsy ◽  
Team Approach ◽  
Vascular Tumour ◽  
Uncertain Malignant Potential ◽  
Glomus Tumors ◽  
History Of ◽  
Intracytoplasmic Lumina

<div class="WordSection1"><p class="abstract">Glomus tumors are rare soft-tissue neoplasms of the neuromyoarterial glomus body, typically present in adults as small, blue-red papules or nodules of the distal extremities, with most cases involving subungual sites. The majority of glomus tumors are benign, malignant cases have been rarely reported, with such cases typically being locally invasive. 27 years old patient presented with four years history of intermittent swelling, pain in left lower leg. Biopsy of the lesion revealed lobulated vascular tumour composed of endothelial cells showing intracytoplasmic lumina and solid aggregates of tumour cells, divided by intervening fibrocollagenous septae. Glomus tumour of uncertain malignant potential was diagnosed after excision biopsy. Multispeciality team approach was done for complete cure of the condition.</p></div>

scholarly journals Glomus Tumor of Uncertain Malignant Potential: A Rare Case Report

2020 ◽  
Vol 3 (1) ◽  
pp. 14-17
Author(s):  
Mehta Shailee ◽  
◽  
Dabral Ritwika ◽  
Trivedi Priti ◽  
◽  
...  
Keyword(s):  
Soft Tissues ◽  
Glomus Tumor ◽  
Malignant Potential ◽  
Uncertain Malignant Potential ◽  
Current Case ◽  
Glomus Tumors ◽  
Large Size ◽  
Rare Case Report ◽  
Mitotic Figures

Glomus tumor is usually a small, benign tumor and typically occurs in the dermis or subcutis or soft tissues of the extremities and rarely in the visceral locations. Its bronchopulmonary origin is exceedingly rare clinical condition. The current case reported a 51-year-old male with dyspnea on exertion and obstructive pneumonia; he had a glomus tumor which has large size, deep location and exhibits an infiltrative margin as well as atypical mitotic figures. These characteristic suggests malignant behavior. Therefore diagnosis of glomus tumor of uncertain malignant potential was favored. Recently, the histopathological diagnostic criteria for malignant glomus tumors were defined in the WHO classification of soft tissue and bone tumors 4th edition. Here we also reviewed the literature on primary bronchopulmonary glomus tumors with special attention to the current concept of malignancy grade estimation.

scholarly journals Glomangioma of Uncertain Malignant Potential: A Case Report

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Meghan McCullough ◽  
Bonnie Balzer ◽  
Stuart H. Kuschner
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Glomus Tumor ◽  
Malignant Potential ◽  
Benign Tumors ◽  
Uncertain Malignant Potential ◽  
Glomus Tumors ◽  
Soft Tissue Masses ◽  
High Index Of Suspicion ◽  
And Behavior

Glomus tumors are rare benign tumors which commonly affect the hand but are seldom seen extradigitally. Less commonly seen is the glomangioma, a variant of benign glomus tumor, and even rarer is the glomangiosarcoma, a malignant variant. Determining malignancy can be difficult and an intermediate diagnosis, glomus tumor of uncertain malignant potential, has been proposed. We present a case of a 56-year-old male with a recurrent forearm mass diagnosed as a glomangioma of uncertain malignant potential. Although the characteristics and behavior of malignant cases are still incompletely understood, it is important that a high index of suspicion be maintained when approaching these tumors, especially when large or recurrent. Glomangiomas should be included in the differential diagnosis when evaluating soft tissue masses in the forearm and should be evaluated for malignant features.

scholarly journals Intravascular Glomus Tumor of the Forearm Causing Chronic Pain and Focal Tenderness

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Sang Ki Lee ◽  
Dae Geon Song ◽  
Won Sik Choy
Keyword(s):  
Chronic Pain ◽  
Glomus Tumor ◽  
Rare Condition ◽  
Surgical Excision ◽  
Vascular Tumor ◽  
Glomus Tumors ◽  
Contrast Magnetic Resonance ◽  
History Of ◽  
Subcutaneous Layer ◽  
Magnetic Resonance Imaging Mri

Introduction. A glomus tumor is a benign vascular tumor derived from glomus cells and occurs mainly in the subcutaneous layer of the subungual or digital pulp. Extradigital glomus tumors have been reported within the palm, wrist, forearm, foot, bone, stomach, colon, cervix, and mesentery. Glomus tumors can originate from the intraosseous, intramuscular, periosteal, intravascular, and intraneural layers. However, a glomus tumor originating from the intravascular layer of the forearm is a rare condition.Case Report. A 44-year-old woman had a 7-year history of chronic pain and focal tenderness of the forearm. No hypersensitivity or sensory alterations were observed. Contrast magnetic resonance imaging (MRI) showed a mass measuring 5 × 3 × 2 mm leading to a vein. Surgical excision was performed, and the tumor was completely resected. Finding of gross examination revealed a dark-red, well-defined soft tissue tumor, and histologic examination confirmed that the mass was a glomus tumor. The patient’s symptoms were completely resolved postoperatively.Conclusion. Intravascular glomus tumors rarely occur in the forearm; therefore, a thorough physical exam, comprehensive medical history, in-depth imaging, and early surgical excision upon clinical suspicion may be helpful to prevent a delayed or incorrect diagnosis.

Behavior of primary tracheal glomus tumor, uncertain malignant potential subtype

2019 ◽  
Vol 67 (11) ◽  
pp. 991-995
Author(s):  
Yuxing Jin ◽  
Samer AL Sawalhi ◽  
Deping Zhao ◽  
Haomin Cai ◽  
Ahmad M. Odeh ◽  
...  
Keyword(s):  
Glomus Tumor ◽  
Malignant Potential ◽  
Uncertain Malignant Potential

Glomus Tumor of the Toe

2017 ◽  
Vol 107 (3) ◽  
pp. 257-260 ◽  
Author(s):  
Robert L.B. Sprinkle ◽  
Omar P. Sangueza ◽  
Gregory A. Schwartz
Keyword(s):  
Glomus Tumor ◽  
The Body ◽  
Cold Sensitivity ◽  
Middle Phalanx ◽  
Soft Tissue Lesion ◽  
Glomus Tumors ◽  
Common Presentation ◽  
Neoplastic Lesion ◽  
Second Toe ◽  
Glomus Body

A glomus tumor is an uncommon, predominantly benign, neoplastic lesion that primarily involves a thermoregulatory microvascular apparatus, the glomus body. Although these lesions can occur anywhere in the body, the subungual tissue of the hand represents the most common presentation site. Glomus tumors are not often encountered in the foot. Symptoms traditionally include the classic triad of pain, pressure, and cold sensitivity. This case report describes a variant location for a glomus tumor in the subcuticular tissue adjacent to the medial middle phalanx of the second toe. The nonsubungual location for this presentation should prompt the inclusion of glomus tumor in a digital soft-tissue lesion differential diagnosis. The lesion was excised surgically and was subsequently diagnosed histopathologically as a glomus tumor.

scholarly journals Malignant Glomus Tumor (Glomangiosarcoma) of Intestinal Ileum: A Rare Case Report

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Ahmed Abu-Zaid ◽  
Ayman Azzam ◽  
Tarek Amin ◽  
Shamayel Mohammed
Keyword(s):  
Glomus Tumor ◽  
Single Case ◽  
Abdominal Mass ◽  
Benign Tumors ◽  
Histopathological Diagnosis ◽  
Glomus Tumors ◽  
First Case ◽  
Rare Case Report ◽  
English Medical Literature ◽  
History Of

Glomus tumors are rare mesenchymal neoplastic lesions arising from glomus bodies that are involved in skin thermoregulation. They are mostly benign tumors, and malignant variants have been rarely reported. The subungual zones of fingers and toes are the most frequent sites of observation. Glomus tumors arising in visceral organs of the gastrointestinal tract are exceedingly rare. Stomach antrum and intestinal duodenum are the most frequent organs involved. No single case of glomus tumor involving intestinal ileum has been previously reported in the English medical literature. To the best of our knowledge, we report the first case of malignant glomus tumor (glomangiosarcoma) of intestinal ileum in a 29-year-old female patient who presented with a 1-month history of a tender pelvi-abdominal mass, constipation, vomiting, and melena. The intestinal ileum glomus tumor was resected, and histopathological diagnosis was consistent with glomangiosarcoma. A postoperative 6-month followup failed to show any evidence of tumor recurrence.

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