scholarly journals Effects of Carvacrol and Volatile Fraction of Winter Savory (Satureja montana L.) on Body Temperature in Humans Who Experience Cold Sensitivity

2013 ◽  
Vol 19 (6) ◽  
pp. 1085-1092 ◽  
Author(s):  
Hideki MASUDA ◽  
Noriyuki MORI ◽  
Yoko MATSUI ◽  
Keiko TSUKIYAMA ◽  
Osamu NISHIMURA ◽  
...  
2016 ◽  
Vol 22 (1) ◽  
pp. 135-144 ◽  
Author(s):  
Hideki Masuda ◽  
Noriyuki Mori ◽  
Kaori Matsui ◽  
Shoko Wakimura ◽  
Daisuke Chino ◽  
...  

Pharmaceutics ◽  
2019 ◽  
Vol 12 (1) ◽  
pp. 7 ◽  
Author(s):  
Alessandro Maccelli ◽  
Luca Vitanza ◽  
Anna Imbriano ◽  
Caterina Fraschetti ◽  
Antonello Filippi ◽  
...  

Chemical fingerprints of four different Satureja montana L. essential oils (SEOs) were assayed by an untargeted metabolomics approach based on Fourier-transform ion cyclotron resonance (FT-ICR) mass spectrometry (MS) coupled with either electrospray ionization or atmospheric pressure chemical ionization ion sources. Analysis and relative quantification of the non-polar volatile fraction were conducted by gas chromatography (GC) coupled to MS. FT-ICR MS confirmed significant differences in the polar metabolite composition, while GC-MS analyses confirmed slight fluctuations in the relative amount of major terpenes and terpenoids, known to play a key role in antimicrobial mechanisms. Oil in eater (O/W) nanoemulsions (NEs) composed by SEOs and Tween 20 or Tween 80 were prepared and analyzed in terms of hydrodynamic diameter, ζ-potential and polydispersity index. The results confirm the formation of stable NEs homogeneous in size. Minimum inhibitory and minimum bactericidal concentrations of SEOs were determined towards Gram-positive (Listeria monocytogenes, Staphylococcus aureus, Staphylococcus haemolyticus) and Gram-negative clinical isolates (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Serratia marcescens). Commercial SEO showed strongest antibacterial activity, while SEO 3 was found to be the most active among the lab made extractions. MIC and MBC values ranged from 0.39 to 6.25 mg·mL−1. Furthermore, a SEO structured in NEs formulation was able to preserve and improve antimicrobial activity.


2016 ◽  
Vol 22 (6) ◽  
pp. 817-827 ◽  
Author(s):  
Hideki Masuda ◽  
Noriyuki Mori ◽  
Yuka Hirobe ◽  
Risako Tanaka ◽  
Daisuke Chino ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-8
Author(s):  
Keiichiro Sugimoto ◽  
Hiroaki Takeuchi ◽  
Kazuya Nakagawa ◽  
Yasuhiro Matsuoka

Ginger is known to warm the body. Therefore, we conducted a placebo-controlled crossover trial to investigate the hyperthermic effect of a palatable ginger-containing beverage in healthy women with cold-sensitive extremities. Six women drank 280 mL of 0.07% ginger extract-containing or placebo beverage in a temperature-controlled room (21°C). Their palm temperatures were measured as measure of surface body temperature using a thermographic camera before intake and every 10 min after intake for 60 min. Palm temperature increased immediately following intake of the ginger and placebo beverages. However, palm temperature following intake of the ginger beverage increased for 20 min, while palm temperature following placebo intake decreased again after 10 min. The increased palm temperature following ginger intake was maintained significantly longer than after placebo intake (p < 0.05). In response to a questionnaire, some subjects answered that their increased body temperature was maintained after drinking the ginger beverage. Ginger extract-containing beverage may thus improve cold sensitivity.


2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Józef Rzepa ◽  
Mieczysław Sajewicz ◽  
Tomasz Baj ◽  
Patrycja Gorczyca ◽  
Magdalena Włodarek ◽  
...  

It was the aim of this study to compare the efficiency of the different essential oil extraction methods upon the two winter savory (Satureja montana) samples of different origin. The compared techniques were the headspace gas chromatography with mass spectrometric detection (HS-GC/MS) run at the two different headspace temperatures (i.e., at 80 and 100°C) and the three different steam distillation techniques preceding the GC/MS analysis. HS-GC/MS is considered as the technique of the first choice, and the compared steam distillation techniques are recommended, respectively, by Polish Pharmacopoeia, European Pharmacopoeia, and the Polish Patent. Adequate conclusions were drawn as to the advantage of HS-GC/MS (not having the pharmacopoeial recommendation) over the different steam distillation techniques and the drawbacks of each individual analytical procedure were discussed.


1998 ◽  
Vol 201 (6) ◽  
pp. 793-803 ◽  
Author(s):  
J E Østnes ◽  
C Bech

Metabolic rate (MR) and various body temperatures were recorded in pigeons Columba livia during gradual lowering of the ambient temperature (Ta) and during cold exposure (-10 degrees C) for an entire circadian cycle. The aim was to study how changes in MR accorded with the observed body temperature displacements and our knowledge of regional cold sensitivity. When Ta was lowered from 28 to -10 degrees C, the threefold increase in MR was accompanied by a significant increase in deep-body and spinal cord temperatures. Cold exposure also resulted in a distinct rise in breast skin temperature, whereas the skin temperatures of the neck, back and leg decreased significantly. Thus, during acute cold exposure of pigeons, peripheral thermosensors seem to have the primary effect in mediating metabolic cold defence, while internal thermosensors are apparently of minor importance. By using differential weightings of various skin areas, cold-sensitivity values of between -3.9 and -14. 7 W kg-1 degrees C-1 were estimated. These values indicate a much higher skin thermosensitivity of birds than has been previously suggested. When cold-exposed for an entire circadian cycle, the pigeons usually maintained a low leg skin temperature. However, during these experiments, the pigeons showed regular distinct increases in leg skin temperature, obviously due to cold-induced vasodilatations (CIVDs). The flushing of cold peripheral blood through the body in connection with these CIVDs resulted in a decrease in deep-body temperature (Tb), to which the pigeons responded with a distinct increase in MR. From the concomitant changes in MR and Tb, a total body cold sensitivity of -8.0 W kg-1 degrees C-1 was calculated, a value that is close to the previously published cold-sensitivity value of pigeons. This shows that, at least under some naturally occurring conditions, internal thermosensors will provide a significant error signal in the control of metabolic cold defence. Furthermore, the results of our study show that the relative importance of various thermosensitive sites in the control of metabolic cold defence is contextual.


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