scholarly journals Inhibitory Effects of 6-Methylsulfinylhexyl Isothiocyanate on Superoxide Anion Generation from Differentiated HL-60 Human Promyelocytic Leukemia Cells

2017 ◽  
Vol 23 (2) ◽  
pp. 343-348 ◽  
Author(s):  
Tomoe Yamada-Kato ◽  
Isao Okunishi ◽  
Yosuke Fukamatsu ◽  
Yusuke Yoshida
Keyword(s):  
Superoxide Anion ◽  
Promyelocytic Leukemia ◽  
Leukemia Cells ◽  
Inhibitory Effects ◽  
Superoxide Anion Generation

Inhibitory effects of cardols and related compounds on superoxide anion generation by xanthine oxidase

2015 ◽  
Vol 166 ◽  
pp. 270-274 ◽  
Author(s):  
Noriyoshi Masuoka ◽  
Ken-ichi Nihei ◽  
Ayami Maeta ◽  
Yoshiro Yamagiwa ◽  
Isao Kubo
Keyword(s):  
Xanthine Oxidase ◽  
Superoxide Anion ◽  
Inhibitory Effects ◽  
Superoxide Anion Generation ◽  
Related Compounds

scholarly journals Chemical Constituents of the Leaves of Peltophorum pterocarpum and Their Bioactivity

Molecules ◽  
2019 ◽  
Vol 24 (2) ◽  
pp. 240 ◽  
Author(s):  
Yue-Chiun Li ◽  
Ping-Chung Kuo ◽  
Mei-Lin Yang ◽  
Tzu-Yu Chen ◽  
Tsong-Long Hwang ◽  
...  
Keyword(s):  
Superoxide Anion ◽  
Methanol Extract ◽  
Chemical Constituents ◽  
Mass Spectrometric ◽  
Inhibitory Effects ◽  
Superoxide Anion Generation ◽  
Chemical Structures

Two new sesquiterpenoids peltopterins A and B (compounds 1 and 2) and fifty-two known compounds were isolated from the methanol extract of P. pterocarpum and their chemical structures were established through spectroscopic and mass spectrometric analyses. The isolates 40, 43, 44, 47, 48, 51 and 52 exhibited potential inhibitory effects of superoxide anion generation or elastase release.

scholarly journals Inhibitory Effects of Indirubin Derivatives on the Growth of HL-60 Leukemia Cells

2010 ◽  
Vol 5 (1) ◽  
pp. 1934578X1000500
Author(s):  
Nguyen Manh Cuong ◽  
Bui Huu Tai ◽  
Dang Hoang Hoan ◽  
Tran Thu Huong ◽  
Young Ho Kim ◽  
...  
Keyword(s):  
Cell Viability ◽  
Cancer Cells ◽  
Trypan Blue ◽  
Promyelocytic Leukemia ◽  
Leukemia Cells ◽  
Cytotoxic Activities ◽  
Inhibitory Effects ◽  
Trypan Blue Exclusion ◽  
Trypan Blue Exclusion Method ◽  
Exclusion Method

Six indirubin derivatives have been synthesized and their inhibitory effects on the growth of HL-60 human promyelocytic leukemia cells investigated. Cell viability was determined using the trypan blue exclusion method. Indirubin-3′-oxime (I-1) inhibited the growth of HL-60 cells with a GI50 value of 36.6 μM, whereas I-0, I-2, I-3, I-4 and I-6 showed only weak cytotoxic activities against HL-60 cancer cells with GI50 values in the range of 97.3 to over 100 μM. These results indicate that indirubin derivatives might be useful candidate agents for exploring potential antileukemic drugs.

Inhibitory Effects of N-acetylcysteine on Superoxide Anion Generation in Human Polymorphonuclear Leukocytes

1997 ◽  
Vol 49 (5) ◽  
pp. 525-529 ◽  
Author(s):  
VICTORIA VILLAGRASA ◽  
JULIO CORTIJO ◽  
MIGUEL MARTÍ-CABRERA ◽  
JOSÉ L. ORTIZ ◽  
LUISA BERTO ◽  
...  
Keyword(s):  
Superoxide Anion ◽  
Polymorphonuclear Leukocytes ◽  
Inhibitory Effects ◽  
Superoxide Anion Generation ◽  
Human Polymorphonuclear Leukocytes
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