12 Regression towards the Mean: Its Etiology, Diagnosis, and Treatment

Author(s):  
David L. Streiner
2001 ◽  
Vol 26 (6) ◽  
pp. 547-549 ◽  
Author(s):  
S. NISHIKAWA ◽  
S. TOH ◽  
H. MIURA ◽  
K. ARAI ◽  
T. IRIE

Thirty-seven patients with dorsal wrist ganglia underwent arthroscopic resection. The mean follow-up was 20 months, and no complications were encountered. The ganglia were classified into three types according to their arthroscopic appearance. This classification helps to determine the amount of dorsal capsular resection required.


2018 ◽  
Vol 8 (4) ◽  
Author(s):  
Viet Hoa Nguyen

Abstract Introduction: Evaluating the role of laparoscopic for diagnosis and treatment of undescended testis in children. Material and Methods: Restrospective study, between 6/ 2014 and 6/2017. All the patients are aged from 1 to 16 years with undescended testis underwent laparoscopic surgery for diagnosis and treatment in Deparment of pediatric surgery – Viet Duc hospital enrolled. Results: Of 95 patiens in total had 106 undescended testis diagnosed and treated by laparoscopy. The mean age of patients was 7,5 ± 3,8 years. 44,2% undescended were on the left side, 44,2% were on the right and 11,6% were undescended bilateral. The correct diagnosis by ultrasound accounted in 79,4%. The locations of testis diagnosed by laparoscopic are : intra abdomen in 45,3%, deep inguinal orifice in 16,9%, extra inguinal orifice in 26,4%, no testicle found in 11,4%. The mean time of operation were 67,33± 28,01 pht. Scrotal positions were achieved 74,5%, remove atrophic testis accounted in 7,6%. Stephen- Flowler technique including step I were in 4,7%, step II in 1,9%. The outcome evaluated by testicular positions following 3 months after operation are : good in 79,2%, moderate 13,2%, poor in 7,6%; By classification of Aubert are : good in 81,1%, moderate in 11,3% and poor in 7,6 %. Conclusion: Laparoscopic surgery is not only a highly sensitive diagnostic method to find accurately the location and size of the testes, but also the most effective method to treat impalpable undescended testes.


PEDIATRICS ◽  
1972 ◽  
Vol 49 (4) ◽  
pp. 606-608
Author(s):  
Paul Harris ◽  
Marshall R. Holley

Blood lead levels were determined on 24 mothers during labor and on the blood of their newborn offspring. The mean value for the mother's blood lead was 13.2 µg/100 gm (range 10 to 20) and for the cord blood 12.3 (range 10 to 20) µg/100 gm whole blood. These levels are lower than "normal" blood lead standards usually accepted in the diagnosis and treatment of childhood lead poisoning.


2019 ◽  
Vol 27 (3) ◽  
pp. 230949901988121 ◽  
Author(s):  
Hasan U Oğur ◽  
Rana Kapukaya ◽  
Özgür Külahçı ◽  
Cengiz Yılmaz ◽  
Kemal Yüce ◽  
...  

Aim: To investigate the diagnosis and treatment methods of soft tissue involvement of hydatid cysts (HCs). Materials and Methods: Eleven patients who were diagnosed as having HC with muscular tissue (soft tissue) involvement between 2010 and 2016 were evaluated retrospectively. Seven patients had typical HC magnetic resonance imaging (MRI) and four patients had cysts with an unusual appearance. We evaluated how to diagnose the cysts using imaging methods, their characteristic radiologic images, and treatment alternatives against the disease. The patients were treated with antihelminthic chemotherapy preoperatively and postoperatively. Results: Of the 11 patients who underwent treatment, 7 were diagnosed using MRI and 4 were diagnosed with histopathologic examinations. The mean follow-up period was 16 (range, 6–24) months, and the mean age was 39.4 (range, 24–56) years. In seven patients, multivesicular appearance with specific MRI findings, T2-hypointense rim appearance, double-rim sign, membrane dissociation, and appearance of daughter cysts were identified as diagnostic criteria. Two patients underwent ultrasound assisted percutaneous aspiration–injection–reaspiration (PAIR) treatment. Seven patients underwent total pericystectomy, and two patients underwent subtotal pericystectomy with serum saline injection into the cyst. Two patients showed signs of mild anaphylaxis, one during the diagnosis and one during treatment. Conclusion: There may be difficulties in the diagnosis and treatment of HCs of the musculoskeletal system. It should be known that there are alternative methods in the treatment (cyst excision and PAIR treatment). Clinical, serologic, and radiologic findings should be used in the diagnosis. To avoid complications during the histopathologic diagnosis, MRI should be examined in detail. It is thought that atypical cysts can be diagnosed (double-layer appearance and peripheral rim sign) in addition to typical cysts (detached membrane and multivesicular appearance), and diagnosis and treatment can be planned without anaphylactic complications.


2017 ◽  
Vol 07 (01) ◽  
pp. 045-051
Author(s):  
Murali Patla ◽  
Sonika Achalli ◽  
K. Saidath ◽  
Crystal Runa Soans ◽  
U.S. Krishna Nayak

AbstractBackground and objectives: The successful treatment of orthognathic surgical patient is dependent on careful diagnosis. The first step in the diagnosis of the patient for orthognathic surgery is to determine the nature of the skeletal, dental and soft tissue defects. Cephalometrics for orthognathic surgery (COGS) analysis by Burstone and colleagues is especially adapted for the diagnosis and treatment planning of orthognathic surgery cases. Burstone and colleagues' COGS analysis are based on Caucasian whites; they may not be applicable as a reference for the diagnosis and treatment of Kerala population patients. Therefore it has become important to determine the cephalometric parameters for this ethnic group. Methodology: Cephalometric radiographs of 50 Keralite adults (25 Males and 25 Females) were analysed who met criteria of the study. The Mean values of various skeletal, dental, angular and linear measurements of Keralites were compared with the White Americans values, originally obtained by Burstone. Results: Statistically significant differences were found in the Keralite samples, who had a greater Anterior and Posterior Cranial base length, Mandibular protrusion, Lower anterior facial heights, Anterior and Posterior Dental heights, Proclined Upper and Lower incisor with less Prominent Chin in comparison to Caucasian. Interpretation and conclusion: This is indicative of disparity between cephalometric norms of Caucasians and Keralites. However conclusions can't be drawn from a single study, hence further studies to establish the cephalometric norms for different ethnic groups across the country may be advisable.


1996 ◽  
Vol 63 (3) ◽  
pp. 394-397
Author(s):  
S. Ciampalini ◽  
A. Lissiani ◽  
E. Belgrano

Laparoscopy has proved to be the most reliable technique in the diagnosis and treatment of nonpalpable testis found in almost 20% of cryptorchid cases. Possible applications are laparoscopic exploration in order to visualise a vanishing testis, Fowler-Stephens orchidopexy and orchiectomy. In orchiectomy, the use of laparoscopy is indicated in adults with single nonpalpable testis, while it is reasonable to use it in severely compromised cases when there is a bilateral nonpalpable testis. Finally it should be used when severe testicular hypotrophy is found. We performed laparoscopic orchiectomy in 6 men at the Departments of Urology of Sassari and Trieste from 1991 to 1996. The mean time of the operation was 1 hour and 50 mins with 1 day hospitalisation. No complications occurred.


2012 ◽  
Vol 18 (4) ◽  
pp. 387-390 ◽  
Author(s):  
Gary R Cutter

Relapse rates and thus the impact of therapies have been decreasing. Why they decline and the impact on our ability to understand which treatments are better require more than simple math. The objective of this review is to discuss the impact of regression to the mean, changes in outcome effects and how we compare outcomes over time and among studies. This paper provides discourse on the topics of regression to the mean, some examples of the pitfalls of changes and some difficulties in the interpretation of the common percentage change in outcomes. The results show that we can often be deceived by what we think we see and they also demonstrate how such confusion evolves in the literature. This article aims to caution against the over-interpretation of changes from baseline, which are helped along by regression towards the mean and other factors. Furthermore, how we interpret changes from baseline requires care and not wishful thinking, coupled with careful digestion of seemingly reasonable explications of results.


Author(s):  
Cengiz Güney ◽  
Abuzer Coskun

Background: Poisoning constitutes an important part of morbidity and mortality among environmental emergencies that can be prevented, frequent in childhood, requiring rapid diagnosis and treatment. This study aimed was to examine the epidemiological, clinical and therapeutic characteristics of drug and corrosive poisonings in terms of children. Materials and Methods: Between January 2010 and December 2018, 1678 patients between the ages of 1-16 who applied to the emergency department with drug and corrosive poisoning were included in the study. The patients were divided into three groups as 1-5, 6-11 and over 12 years of age, and the substances with known pharmacological agents were divided into 10 groups. The Zargar Classification (7) was used to determine the degree of damage caused by corrosive substances in the esophagus. Results: The mean age of the patients was 8.32 ± 3.23 years (1-15 years). The girl/boy ratio of the cases was 1.18 / 1 and 54.3% were girls. 18.9% of the cases were under five years of age, 61% were between 6-11 years and 20% were older than 12 years. 94.6% of the patients were poisoned by drugs and 5.4% of them were poisoned due to non-drug reasons. Accidental poisoning was most commonly seen in children aged 6-11 and suicides were seen in children older than 12 years. It was found that 62.2% of the poisonings were accidental and 37.8% were suicidal. The most common causes of poisoning were analgesics and paracetamol exposure as a pharmacological agent. Mortality was found to be most common in 1-5 years age group and accidental poisonings. Accidental poisoning was common in girls and suicidal poisoning was common in boys. Grade 3 damage was found endoscopically in all of the mortalities due to corrosive substances. Conclusion: It was found that accidental poisoning was observed in children under five years of age, suicides were observed in children older than 12 years and the most important cause of mortality was due to corrosive substances. Cause-specific rapid diagnosis and treatment will contribute to the reduction of morbidity and mortality.


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