scholarly journals CORRECTION OF RESISTANT ARTERIAL HYPERTENSION IN PATIENTS WITH CHRONICKIDNEYDISEASE STAGE I–III

Author(s):  
O. M. Loboda

Aim. The aim was to investigate the use of the I1–imidazoline receptor agonist moxonidine as an ‘add–on’ agent and determine its effect on heart rate variability in patients with CKD st. I–III and resistant hypertension. Methods. We investigated the safety and efficacy of moxonidine (200–600 mg) in a group of 35patients with CKD st. I–III whose had prior treatment with three or more antihypertensive medications, although without adequate control [systolic blood pressure (SBP) 145–165 mm Hg and/or diastolic BP (DBP) 95–100 mm Hg]. BP was measured according to internationally accepted guidelines before and after 3 month of treatment with moxonidine used as an ‘add–on’ agent in the patients with CKD st. I–III and resistant hypertension. Age ofpatients was 53±5,8 years. Glomerular filtration rate (GFR) before treatment was 68,7±23,0 mL/min/1,73m 2. Before and 3 months after treatment, we determined improvement in the time–frequency analysis of heart rate variability. Results. Following treatment with moxonidine, the SBP significant fell from 153.6±8.1 to 130.7±4.6 mmHg (P< 0.001). The DBP also showed a significant reduction from 96.7±2,4 to 80.9±2,6 mmHg (P< 0.001). Reduction of SBP pressure was 22.9±7.9 mm Hg and reduction of DBP was 15.9±3.1 mm Hg. 29patients (83%) achieved the goal blood pressure – 130/80 mm Hg and less. 5 patients (14%) were not achieve goal blood pressure, but blood pressure lowered <140/90 mm Hg. In 1 patient (3%) blood pressure decreased from 160/100 mm Hg to 145/90 mm Hg. The majority of patients (28 – 80%)

Author(s):  
Arundhati Goley ◽  
A. Mooventhan ◽  
NK. Manjunath

Abstract Background Hydrotherapeutic applications to the head and spine have shown to improve cardiovascular and autonomic functions. There is lack of study reporting the effect of either neutral spinal bath (NSB) or neutral spinal spray (NSS). Hence, the present study was conducted to evaluate and compare the effects of both NSB and NSS in healthy volunteers. Methods Thirty healthy subjects were recruited and randomized into either neutral spinal bath group (NSBG) or neutral spinal spray group (NSSG). A single session of NSB, NSS was given for 15 min to the NSBG and NSSG, respectively. Assessments were taken before and after the interventions. Results Results of this study showed a significant reduction in low-frequency (LF) to high-frequency (HF) (LF/HF) ratio of heart rate variability (HRV) spectrum in NSBG compared with NSSG (p=0.026). Within-group analysis of both NSBG and NSSG showed a significant increase in the mean of the intervals between adjacent QRS complexes or the instantaneous heart rate (HR) (RRI) (p=0.002; p=0.009, respectively), along with a significant reduction in HR (p=0.002; p=0.004, respectively). But, a significant reduction in systolic blood pressure (SBP) (p=0.037) and pulse pressure (PP) (p=0.017) was observed in NSSG, while a significant reduction in diastolic blood pressure (DBP) (p=0.008), mean arterial blood pressure (MAP) (p=0.008) and LF/HF ratio (p=0.041) was observed in NSBG. Conclusion Results of the study suggest that 15 min of both NSB and NSS might be effective in reducing HR and improving HRV. However, NSS is particularly effective in reducing SBP and PP, while NSB is particularly effective in reducing DBP and MAP along with improving sympathovagal balance in healthy volunteers.


2009 ◽  
Vol 6 (3) ◽  
pp. 38-56
Author(s):  
G V Ryabykina ◽  
T A Shishova ◽  
D N Laptev ◽  
V B Mychka ◽  
L N Lyutikova ◽  
...  

Aim: this study the changes of blood pressure (BP), heart rate variability (HRV) characteristics, average weighed rhythmogram variation (AWRV) and QTc in patients with metabolic syndrome (MC) and arterial hypertension (AH) before and after therapy of betablocker, metformin and their combination. Materials: 51 patients with МС and AH were enrolled in the study. The patients were randomization on 3 groups: the monotherapy of nebivolol (N) 5 mg/days (n=18), the monotherapy of metformin (M) 1700 mg/days (n=15) and nebivolol+metformin combination therapy (N+M) (n=18). The estimated variables included of BP, HRV, AWRV and QTc before and after 24 weeks of the treatment. Results: after 24 weeks of the N treatment QTc interval change from 44823 ms to 43317ms (p0.05). Treatment of M changes AWRV from 872234 ms to 761195 (p>0.05), QTc from 44825 ms to 43427 ms (p


Author(s):  
Kang-Ming Chang ◽  
Miao-Tien Wu Chueh ◽  
Yi-Jung Lai

Background: It is well known that meditation improves the physical and psychological condition of its practitioners. This study investigated the heart rate variability response of meditation practitioners in two Chan master teaching environments, namely face-to-face and video classes. Methods: Experimental sessions were conducted, one featuring face-to-face classes and the other featuring video classes. The difference in participants’ physiological parameters (blood pressure and heart rate variability) between the two experimental sessions was determined. In the first session, physiological parameters were recorded twice, before and after one teaching course, and the second session took place one month after the first. The first and second sessions had 45 and 27 participants, respectively. Those involved in the first experiment had no experience with meditation, whereas participants in the second experiment had practiced meditation for an average of 9 years (range = 1 to 27 years). Both experiments were conducted once a week, with each session lasting 1.5 h. Results: For both experiments, both heart rate and heart rate variability by age significantly decreased after one teaching course. Conclusions: Chan meditation practitioners benefit from receiving both face-to-face and video class teaching from a Chan master.


2020 ◽  
Vol 30 (03) ◽  
pp. 2050003 ◽  
Author(s):  
K. J. Blinowska ◽  
P. Lachert ◽  
J. Zygierewicz ◽  
D. Janusek ◽  
P. Sawosz ◽  
...  

We evaluated the properties of oscillations in the Mayer waves (MW) frequency range ([Formula: see text][Formula: see text]Hz) detected in blood pressure, heart rate variability, cerebral blood oxygenation changes and evolution of electroencephalographic (EEG) rhythms to elucidate the mechanisms of MW generation. We examined the persistence of MW in different signals and stability of their oscillations on the level of individual MW waveforms, which was achieved by applying matching pursuit (MP). MP yields adaptive time-frequency approximation of signal’s structures in terms of frequency, amplitude, time occurrence, and time-span. The number of waveforms contributing to 95% of the energy of the signals was vastly different for the time series, but the average number of waveforms conforming to the MW criteria was almost the same ([Formula: see text] per 120[Formula: see text]s epoch). In all the investigated signals, MW had the same distributions of frequency and the number of cycles. We show that the MW energy ratios in different signals varied strongly, [Formula: see text]. The highest percentage of MW energy was observed in blood pressure signals, heart rate variability, and reduced hemoglobin, in contrast to brain signals and oxygenated hemoglobin. The percentage of MW energy was related to the strength of causal influence exerted by them on the other signals. Our results indicate existence of a common mechanism of MW generation and support the hypothesis of MW generation in the baroreflex loop; however, they do not exclude the action of a central pacemaker.


2014 ◽  
Vol 32 (3) ◽  
pp. 644-651 ◽  
Author(s):  
Gil F. Salles ◽  
Frederico M. Ribeiro ◽  
Gleison M. Guimarães ◽  
Elizabeth S. Muxfeldt ◽  
Claudia R.L. Cardoso

Author(s):  
Samruddhi Chintaman Vyas ◽  
A. Mooventhan ◽  
N. K. Manjunath

AbstractBackgroundThough hot arm and foot bath (HAFB) is widely used, a precise physiological response is not reported. Hence, the present study was conducted to evaluate the effect of HAFB on heart rate variability (HRV) and blood pressure (BP) in healthy volunteers.Materials and MethodsSixteen healthy male volunteers’ aged 23.81 ± 5.27 (mean ± standard deviation) years were recruited. All the subjects underwent only one session of HAFB (104-degree Fahrenheit) for the duration of 20 min. Assessments such as Electrocardiography and BP were taken before and after the intervention.ResultsResults of this study showed a significant reduction in systolic-BP (SBP), diastolic-BP (DBP), mean arterial pressure (MAP), the mean of the intervals between adjacent QRS complexes or the instantaneous heart rate (RR interval), the number of interval differences of successive NN intervals greater than 50 ms (NN50), the proportion derived by dividing NN50 by the total number of NN intervals (pNN50), and high frequency (HF) band of HRV along with a significant increase in heart rate (HR), low-frequency (LF) band of HRV and LF/HF ratio compared to its baseline.ConclusionsResults of this study suggest that 20 min of HAFB produce a significant increase in HR and a significant reduction in SBP, DBP, and MAP while producing parasympathetic withdrawal.


2020 ◽  
Author(s):  
Liang Wu ◽  
Ping Shi ◽  
Jiang Shao ◽  
Anan Li ◽  
Hongliu Yu ◽  
...  

Abstract Background : Heart rate variability (HRV) provides an opportunity to capture the tiny but early signs that may predict the future cardiovascular risk in healthy individuals and further, helps understand how well the cardiovascular autonomic system works. Aims of this study were to elucidate short-term recovery of HRV and its relationship with blood pressure recovery after different intensity treadmill exercise. Methods : Fifteen healthy participants performed four different conditions (REST; speed 6km/h; speed 8km/h; speed 10km/h), systolic and diastolic blood pressure per 30s (SBP, DBP) and 5-mins consecutive heart beats intervals were measured after each trial. Autonomic nervous regulation was evaluated using HRV time-frequency domain indices and heart rate asymmetry (HRA) indices. Each index was calculated using 5 mins electrocardiogram (ECG) series and consecutive 30-s windows in 5 mins. Results : the vagally related indices (RMSSD, pNN50 and HF) decreased and the indices representing overall variability (SDNN, LF) had different trends as intensity increasing. The sympathetic-vagal balance parameter LF/HF increased, too. HRV indices had strong correlations with DBP but weak with SBP. Meanwhile, heart rate asymmetry vanished after each trial. Conclusions : The findings suggested a vagal withdrawal as soon as the end of treadmill exercise. It could be concluded that sympathetic modulation was stronger as intensity increasing. During recovery period, DBP was mediated by vagal activation and sympathetic withdrawal. The diminished asymmetry in Poincaré plot was the result of sympathetic acceleration and vagal reduction.


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