scholarly journals Primary Retroperitoneal Serous Cystadenoma Mimicking Rectal Duplication Cyst: A Case Report

2020 ◽  
pp. 1-3
Author(s):  
Valentine Nfonsam ◽  
Hunter Jecius ◽  
Mary Junak ◽  
Mohammad Hamidi ◽  
Valentine Nfonsam
Keyword(s):  
Urinary Incontinence ◽  
Single Layer ◽  
Exploratory Laparotomy ◽  
Serous Cystadenoma ◽  
Duplication Cyst ◽  
Simple Cyst ◽  
Large Space ◽  
Serous Cystadenomas ◽  
Prolapse Symptoms ◽  
Primary Retroperitoneal

Background: Primary retroperitoneal serous cystadenomas (PRSCs) are extremely rare, and their pathogenesis is not well understood. Differentiating these tumors from other cystic or tumorigenic lesions can be challenging given the unusual retroperitoneal location and varied symptomatology. Case Presentation: An 83-year-old female was evaluated for vaginal prolapse symptoms, fecal incontinence, and intermittent mixed urinary incontinence symptoms. Magnetic resonance imaging showed a large space-occupying cystic structure closely associated with the rectum. After exploratory laparotomy with excision of the retroperitoneal mass, biopsy showed a simple cyst filled with serous fluid and lined by a single layer of cuboidal epithelial cells consistent with serous cystadenoma. On follow up visit, she reported improvement in stress urinary incontinence, but continued to have difficulty with urinary and bowel urge incontinence. Conclusion: PRSCs should be considered during evaluation of retroperitoneal space-occupying lesions despite the rarity of serous cystadenomas being found in this location. The pathophysiology of how PRSCs arise is still not well understood but establishing better techniques to distinguish these lesions from other cystic and tumorigenic lesions should be investigated.

scholarly journals Giant Primary Retroperitoneal Serous Cystadenoma: A Rare Entity Mimicking Multiple Neoplastic and Nonneoplastic Processes

2019 ◽  
Vol 144 (4) ◽  
pp. 523-528
Author(s):  
Fengming Chen ◽  
Kun Jiang
Keyword(s):  
Clinical Presentation ◽  
Ovarian Neoplasms ◽  
Current Knowledge ◽  
Serous Cystadenoma ◽  
Point Of View ◽  
Cyst Excision ◽  
Serous Cystadenomas ◽  
The Common ◽  
Cystic Masses ◽  
Primary Retroperitoneal

Serous cystadenoma, often known as ovarian serous cystadenoma, is one of the common benign ovarian neoplasms. On the other hand, primary retroperitoneal serous cystadenoma is an extremely rare benign entity whose pathogenesis has not been well understood. Clinical presentation and symptomatology vary greatly and are highly dependent on the size and location of the lesion. Primary retroperitoneal serous cystadenomas are homogeneous, unilocular, thin-walled cystic masses. If they grow large enough, they tend to compress and deform adjacent organs, giving clinicians a misimpression of malignant pattern of behavior. Therefore, it is crucial to differentiate benign primary retroperitoneal serous cystadenomas from other epithelial and nonepithelial cystic lesions or masses involving retroperitoneal regions. Management-wise, complete cyst excision without rupture or spillage of the cyst contents is the recommended therapeutic method for primary retroperitoneal serous cystadenomas. This review will highlight the current knowledge on its pathogenesis and discuss its histopathologic features and differential diagnoses from the pathologist's point of view.

scholarly journals A Giant Primary Retroperitoneal Serous Cystadenoma: Case Report and Review of Retroperitoneal Cysts

2017 ◽  
Vol 03 (01) ◽  
pp. e32-e37 ◽  
Author(s):  
Amit Mori ◽  
Kinesh Changela ◽  
Dhuha Alhankawi ◽  
Alexander Itskovich ◽  
Ahmar Butt ◽  
...  
Keyword(s):  
Early Recognition ◽  
Secondary Infection ◽  
Abdominal Distension ◽  
Serous Cystadenoma ◽  
Cystic Lesions ◽  
Surgical Specimen ◽  
Serous Cystadenomas ◽  
History Of ◽  
Work Up ◽  
Primary Retroperitoneal

AbstractPrimary retroperitoneal serous cystadenomas (PRSCs) are rare cystic lesions whose pathogenesis is currently not well understood. Although the vast majority of tumors are benign, early recognition and resection is necessary to avoid malignant transformation, rupture, and secondary infection. Here we present the case of a 79-year-old woman who presented with confusion, visual hallucinations, and a history of fall. As part of the work-up for abdominal distension, computed tomography scan of the abdomen and pelvis was performed, which revealed a right-sided retroperitoneal cystic lesion measuring 26.6 × 16.7 cm in size. The lesion was resected laparoscopically, and the surgical specimen measured 28 × 17 cm. Histology revealed a serous cystadenoma. The postsurgical course was uneventful, and no radiological recurrence was noted on 3 months follow-up. Very few primary retroperitoneal cystic lesions have been reported in the literature. Most lesions are benign and predominantly occur in females. They may remain asymptomatic for long periods of time and are usually discovered when they reach very large in size. In rare cases, these lesions may have malignant potential. Diagnosis of PRSC should be considered in the differential diagnosis of all retroperitoneal cysts.

scholarly journals Primary Papillary Serous Carcinoma of the Peritoneum

2014 ◽  
Vol 8 (2) ◽  
pp. 60-62
Author(s):  
NM Jayakumar ◽  
PS Sangam ◽  
VU Grampurohit ◽  
AF Myagery
Keyword(s):  
Exploratory Laparotomy ◽  
Serous Carcinoma ◽  
Ovarian Malignancy ◽  
Simple Cyst ◽  
Rare Type ◽  
Moderate Amount ◽  
Obstetrics And Gynaecology ◽  
Pain Abdomen ◽  
Eosinophilic Cytoplasm ◽  
Papillary Serous Carcinoma

Primary papillary serous carcinoma of peritoneum (PPSCP) is a rare type of primary peritoneal adenocarcinoma and is clinico-histopathologically indistinguishable from primary ovarian papillary serous carcinoma. A 70 -year- female presented with pain abdomen of 4 months duration. On examination partially mobile vague mass was present in the suprapubic region. Exploratory laparotomy revealed normal right ovary and the left ovary showed simple cyst. Nodular, firm tumour was seen arising from omentum and measured 20x13x9.3 cm. Microscopically tumour was composed of large sheets of polygonal cells having large hyperchromatic and pleomorphic nuclei and moderate amount of eosinophilic cytoplasm forming cribriform pattern and papillae. It has similar prognosis as that of ovarian malignancy. This case of extraovarian papillary serous carcinoma of peritoneum (EPSCP) is presented here for its rarity.Nepal Journal of Obstetrics and Gynaecology / Vol 8 / No. 2 / Issue 16 / July-Dec, 2013 / 60-62 DOI: http://dx.doi.org/10.3126/njog.v8i2.9774

scholarly journals Ovarian huge serous cystadenoma with torsion in adolescent girl: a case report

2017 ◽  
Vol 6 (3) ◽  
pp. 1151
Author(s):  
Shweta Avinash Khade ◽  
Sneha Shirodkar
Keyword(s):  
Differential Diagnosis ◽  
Adolescent Girl ◽  
Serous Cystadenoma ◽  
Ovarian Cysts ◽  
Emergency Laparotomy ◽  
Surgical Removal ◽  
Germ Cell Tumours ◽  
Serous Cystadenomas ◽  
Epithelial Tumours ◽  
Ovarian Masses

In adolescent Ovarian cysts are an extremely common gynaecological problem. Majority of ovarian cysts are benign with few cases being malignant. Ovarian serous cystadenomas are rare in children. A 14-year-old presented with severe abdominal pain and abdominal distention. She underwent emergency laparotomy and surgical removal, the mass was found to be torsion of ovarian serous cystadenoma-fibroma on histology. In conclusions, germ cell tumours the most important causes for the giant ovarian masses in children. Epithelial tumours should not be forgotten in the differential diagnosis.

Massive ovarian edema associated with ovarian serous cystadenoma: a case report and review of the literature

2006 ◽  
Vol 16 (Suppl 1) ◽  
pp. 326-330
Author(s):  
W. E. Khalbuss ◽  
B. Dipasquale
Keyword(s):  
Lower Abdominal Pain ◽  
Single Layer ◽  
Serous Cystadenoma ◽  
Cystic Mass ◽  
Ovarian Neoplasm ◽  
Solid Mass ◽  
Outer Cortex ◽  
First Case ◽  
Massive Ovarian Edema ◽  
Computed Tomography Scanning

Massive ovarian edema is a rare entity that can be confused with an ovarian neoplasm. A few ovarian lesions have been reported that are associated with massive ovarian edema. This article describes the first case of an ovarian serous cystadenoma associated with a massive ovarian edema. The patient was a 17-year-old female who was referred to the emergency room because of lower abdominal pain. Subsequent ultrasound and computed tomography scanning studies revealed an abdominopelvic cystic mass suggestive of an ovarian neoplasm. She underwent an exploratory laparoscopy, and a left salpingo-oophorectomy was performed. The specimen weighed 1610 g and consisted of a cystic mass measuring 17 × 15 × 8 cm attached to a solid mass measuring 13 × 11 × 4 cm. Microscopy revealed a cystic and a solid lesion. The cystic structure was composed of a flat or cuboidal single-layer lining showing ciliated epithelium and focal areas of papillary structures compatible with a diagnosis of ovarian serous cystadenoma. The solid mass had an intact capsule and diffuse interstitial edema, preserving the overall structure of the ovary and sparing the outer cortex. These findings are compatible with the diagnosis of ovarian massive edema. This report of an association of serous cystadenoma with massive ovarian edema broadens the histologic spectrum in which a massive ovarian edema may be encountered.

scholarly journals Pancreatic Serous Cystadenomas Report of 8 Cases with a Mean Follow up of 7 Years

HPB Surgery ◽  
1996 ◽  
Vol 9 (4) ◽  
pp. 215-217 ◽  
Author(s):  
Alejandro Fabiani ◽  
Gonzalo J. Delía ◽  
Roberto De Rosa ◽  
María T. Pombo ◽  
Oscar Molfino ◽  
...  
Keyword(s):  
Gastric Emptying ◽  
Pancreatic Fistula ◽  
Delayed Gastric Emptying ◽  
Acute Cholangitis ◽  
Serous Cystadenoma ◽  
Malignant Potential ◽  
Cystic Tumor ◽  
Serous Cystadenomas ◽  
Pancreatic Cystic Tumor

Serous cystadenoma of the pancreas are rare tumors and have little or no malignant potential.We report our experience in the management of eight casses of these tumors in the last 22 years. All the patients were women with a mean age of 59 years. All the cysts caused symptoms. Ultrasound and CTscan were useful in the diagnosis of the pancreatic cystic tumor out not in determining the nature of these lesions clear. FNA-biopsy was performed in 6 cases but in only one c se was the diagnosis confirmed. All tumors were resected. Four radical pancreatoduodenectomies, two distal pancreatectomies and two cystectomies were performed. Mean followup was 83.5 months. All patients are alive and with no signs of recurrence. Complications include an external pancreatic fistula, an acute cholangitis and a case of delayed gastric emptying. In all cases the histological diagnosis was serous cystadenoma of the pancreas. We conclude that resection of these tumors is mandatory although they are supposed to be benign, in order to avoid complications and because malignant transformations has been related to nonresective treatment.

scholarly journals A Minimum Perturbation Theory of Deep Perceptual Learning

2021 ◽  
Author(s):  
Haozhe Shan ◽  
Haim Sompolinsky
Keyword(s):  
Perceptual Learning ◽  
Network Architecture ◽  
Brain Plasticity ◽  
Deep Structure ◽  
Causal Relation ◽  
Neuronal Response ◽  
Single Layer ◽  
Behavioral Changes ◽  
Large Space ◽  
Deep Network

AbstractPerceptual learning (PL) involves long-lasting improvement in perceptual tasks following extensive training. Such improvement has been found to correlate with modifications in neuronal response properties in early as well as late sensory cortical areas. A major challenge is to dissect the causal relation between modification of the neural circuits and the behavioral changes. Previous theoretical and computational studies of PL have largely focused on single-layer model networks, and thus did not address salient characteristics of PL arising from the multiple-staged “deep” structure of the perceptual system. Here we develop a theory of PL in a deep neuronal network architecture, addressing the questions of how changes induced by PL are distributed across the multiple stages of cortex, and how do the respective changes determine the performance in fine discrimination tasks. We prove that in such tasks, modifications of synaptic weights of early sensory areas are both sufficient and necessary for PL. In addition, optimal synaptic weights in the deep network are not unique but span a large space of solutions. We postulate that, in the brain, plasticity throughout the deep network is distributed such that the resultant perturbation on prior circuit structures is minimized. In contrast to most previous models of PL, the minimum perturbation (MP) learning does not change the network readout weights. Our results provide mechanistic and normative explanations for several important physiological features of PL and reconcile apparently contradictory psychophysical findings.

scholarly journals Serous Cystadenoma of the Pancreas Presenting as a Third Primary Neoplasm

2003 ◽  
Vol 17 (9) ◽  
pp. 552-554 ◽  
Author(s):  
Aydın Şeref Köksal ◽  
Aysel Ülker ◽  
Mehmet Asıl ◽  
Bilge Tunç ◽  
Arda Kemal ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Previous History ◽  
Serous Cystadenoma ◽  
The Body ◽  
Pathological Examination ◽  
Cystic Neoplasms ◽  
Serous Cystadenomas ◽  
History Of ◽  
Primary Neoplasm ◽  
Other Neoplasms

Serous cystadenomas are the most common cystic neoplasms of the pancreas. They may occur solely or coexist with other neoplasms. A 10 cm mass involving the body of the pancreas was observed in the computed tomography of a 61-year-old man with a previous history of bladder and prostate carcinoma. Ultrasonography and computed tomography of the mass demonstrated multiple small cysts associated with a central calcified scar. A distal pancreatectomy was performed. Pathological examination confirmed the diagnosis of serous microcystic adenoma. This is the first report of a serous cystadenoma of the pancreas with two metachronous neoplasms. This feature should be kept in mind during the diagnosis and evaluation of patients with serous cystadenoma.

An Overview of Ovarian Tumours at B.P. Koirala Memorial Cancer Hospital, Nepal

2019 ◽  
Vol 3 (1) ◽  
pp. 44-48
Author(s):  
Chin Bahadur Pun ◽  
Sadina Shrestha ◽  
Ranjan Raj Bhatta ◽  
Greta Pandey ◽  
Suraj Uprety ◽  
...  
Keyword(s):  
Mucinous Cystadenoma ◽  
Cystic Teratoma ◽  
Serous Cystadenoma ◽  
Serous Cystadenocarcinoma ◽  
Cancer Hospital ◽  
Benign Ovarian Tumours ◽  
Serous Cystadenomas ◽  
Ovarian Tumours ◽  
Epithelial Tumours ◽  
Yolk Sac Tumour

Introduction: Ovarian cancer is the seventh most commonly diagnosed cancer among women in the world. This study was conducted with the aim to find out different histological types of ovarian tumours reported at B.P. Koirala Memorial Cancer Hospital (BPKMCH), Chitwan, Nepal. Methods: This was a retrospective study carried out at the Department of Pathology of BPKMCH from January 1, 2018 to December 31, 2018. This study included the patients who were operated at BPKMCH or referred cases from elsewhere, but the specimen was processed and reported at BPKMCH. All the data were retrieved and analyzed from the records of Pathology Department. Results: Altogether 87 cases of ovarian tumours were reported during the study period. Out of which, 31 cases were benign ovarian tumours whereas 56 cases were malignant ovarian tumours. Both benign and malignant ovarian tumours were most common in age group 41 to 50 years of age. Among benign ovarian tumours, 12 cases were serous cystadenoma, 7 cases mucinous cystadenoma, 6 cases mature cystic teratoma, 2 cases serous cyst adenofibroma, 2 cases benign Brenner tumour and 2 endometroid cystadenoma. Among malignant ovarian tumours, 33 cases were serous cystadenocarcinoma, 11 cases mucinous cystadenocarcinoma, 2 cases immature teratoma, 3 cases were malignant sex cord stromal tumours (granulosa cell tumour), 2 cases dysgerminoma, 1 case yolk sac tumour, 1 case endometroid carcinoma and 3 cases were metastatic adenocarcinoma. Conclusion: Surface epithelial tumours were most common ovarian tumours in this study. Serous cystadenomas were most common benign ovarian tumours whereas serous cystadenocarcinomas were the most common malignant ovarian tumours.  

scholarly journals Fifteen-Year Follow-Up of a Patient with Acinar Cystic Transformation of the Pancreas and Literature Review

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Xiaoyun Wen ◽  
Jela Bandovic
Keyword(s):  
Abdominal Pain ◽  
Cystic Lesion ◽  
Pancreatic Head ◽  
Single Layer ◽  
Exploratory Laparotomy ◽  
Final Diagnosis ◽  
Cystic Neoplasm ◽  
Histologic Diagnosis ◽  
Ultrasound Surveillance

Acinar cystic transformation (ACT), also known as “acinar cell cystadenoma,” is a rare and newly recognized benign pancreatic cystic neoplasm. However, its true malignant potential remains unknown. Here, we report a case of ACT with 15-year follow-up. A 10-year-old female initially presented with abdominal pain and was found to have a cystic lesion in the region of pancreatic head on computed tomography scan. She underwent an exploratory laparotomy, and the intraoperative biopsy of the cyst wall showed a true pancreatic cyst without malignancy. Her symptoms subsequently resolved, and she was placed under close ultrasound surveillance. For the next fifteen years, the patient was asymptomatic without any complications and had a successful pregnancy. Surveillance showed the tumor grew in size from 4.2 cm to 6.2 cm in diameter. In the latest five months, she noted occasional abdominal pain. A pylorus-preserving pancreaticoduodenectomy was performed. The resected cystic lesion was multilocular and lined by a single layer of bland epithelium ranging from nondescript flat/cuboidal epithelium to apparent acinar cells which were strongly positive for trypsin, so the final diagnosis was confirmed to be ACT. The prior biopsy was retrospectively reviewed to reveal similar epithelial lining. To the best of our knowledge, this is the longest period of follow-up for ACT to date. Our findings suggest that ACT is a slow-growing neoplasm without malignant transformation after fifteen years. Therefore, we recommend biopsy for histologic diagnosis followed by close ultrasound surveillance without surgical intervention in asymptomatic or young ACT patients.

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