scholarly journals Change of Age Distribution of Childhood and Adolescent Thyroid Cancer after the Fukushima Nuclear Accident Compared with the Chernobyl Cases

2020 ◽  
pp. 1-5
Author(s):  
Toshiko Kato ◽  
Toshiko Kato
Keyword(s):  
Thyroid Cancer ◽  
Health Management ◽  
Age Distribution ◽  
Published Data ◽  
Younger Age ◽  
Radiation Induced ◽  
Age Patterns ◽  
The One ◽  
Childhood Thyroid Cancer ◽  
Age At Exposure

Background and Methods: Comparison of age patterns of childhood and adolescent childhood thyroid cancer after the nuclear accidents in Fukushima and Chernobyl is often used as a criterion of radiationinduced thyroid cancer in Fukushima. The Fukushima Health Management Survey reports that thyroid cancers in Fukushima are unlikely to be radiation-induced, and one reason for the conclusion was no case was found in the age of 0-5 years at exposure. Published data on the health effects of the Chernobyl accident were analysed to assess whether there was one age pattern common in Chernobyl to be used as a criterion of radiation-induced thyroid cancer. Various age distributions of thyroid cancer as to the age at exposure and age at diagnosis, which depend on the country and the extent of radiation contamination, were studied as a function of years after exposure. Results and Conclusion: The highest incidence of thyroid cancer for infants aged 0-4 at exposure was observed only in Belarus. The high incidence of age group 0-4 AE became apparent only after 12 years from the accident in Ukraine and Russia. Age distribution of diagnosed or suspected thyroid cancer cases in Fukushima by age at exposure shifts to younger age side, average age from 14.9 to 8.3 years in 9 years after the accident. This trend agrees with the one in Ukraine and Russia. Because there is no common age pattern in Chernobyl, we should better not use age pattern as a simple criterion of radiation-induced thyroid cancer.

scholarly journals Age Distribution of Childhood Thyroid Cancer Patients in Ukraine After Chernobyl and in Fukushima After the TEPCO-Fukushima Daiichi NPP Accident

Thyroid ◽  
2014 ◽  
Vol 24 (10) ◽  
pp. 1547-1548 ◽  
Author(s):  
Mykola D. Tronko ◽  
Vladimir A. Saenko ◽  
Victor M. Shpak ◽  
Tetiana I. Bogdanova ◽  
Shinichi Suzuki ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Patients ◽  
Age Distribution ◽  
Fukushima Daiichi ◽  
Childhood Thyroid Cancer

Ultrasound diagnosis of radiation-induced childhood thyroid cancer in Belarus: 10 years of practical experience

2002 ◽  
Vol 1234 ◽  
pp. 221-229
Author(s):  
Valentina M. Drozd ◽  
Andrej P. Lyshchik ◽  
Evgueni P. Demidchik ◽  
Evgeny D. Cherstvoy ◽  
Vladislav A. Ostapenko ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Practical Experience ◽  
Ultrasound Diagnosis ◽  
Radiation Induced ◽  
Childhood Thyroid Cancer

scholarly journals Childhood thyroid cancer in Belarus, Russia, and Ukraine after Chernobyl and at present

2007 ◽  
Vol 51 (5) ◽  
pp. 748-762 ◽  
Author(s):  
Yuri E. Demidchik ◽  
Vladimir A. Saenko ◽  
Shunichi Yamashita
Keyword(s):  
Thyroid Cancer ◽  
Radiation Risk ◽  
Basic Sciences ◽  
Results Of Treatment ◽  
Radiation Induced ◽  
Sporadic Cases ◽  
Risk Of Disease ◽  
Childhood Thyroid Cancer ◽  
Cancer In Children

Thyroid cancer in children is usually rare, but in the individuals exposed to radiation risk of disease increases considerably. After the Chernobyl accident in 1986, an over 10-fold maximal elevation in the incidence of thyroid cancer was registered about a decade later, cumulatively resulting in more than a thousand of newly diagnosed cases in children who lived in the territories of Belarus, Russia, and Ukraine affected by radioactive fallouts. Experience from the epidemic substantially promoted knowledge in clinical pediatric oncology, pathology and basic sciences. This article overviews epidemiology, clinical features, results of treatment and follow-up of childhood patients with radiation-induced Chernobyl thyroid cancer in comparison to sporadic cases diagnosed at present. In addition, we discuss general issues of pathology and molecular findings in childhood thyroid carcinomas.

scholarly journals Updated Incidence of Thyroid Cancer in the North East Region of Romania after 35 Years of Chernobyl Fallout. Is There a Link between?

Diagnostics ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 907
Author(s):  
Laura Teodoriu ◽  
Maria Christina Ungureanu ◽  
Letitia Leustean ◽  
Cristina Preda ◽  
Delia Ciobanu ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Age Distribution ◽  
Age Groups ◽  
Chernobyl Fallout ◽  
Statistical Correlations ◽  
North East ◽  
The North ◽  
East Region ◽  
Radioactive Cloud ◽  
The Moment

Thyroid cancer (TC) represents a worldwide problem, the consistent growth of the incidence increment issues about management of risk factors and curative treatment. Updated statistical data are not complete in the North East region of Romania and need to be improved. Therefore, through this study, we aim to renew the existing data on thyroid cancer. We conducted a retrospective study covering a period of 10 years. Data were collected from a hospital information system (InfoWorld) between 2009 and 2019. Patients’ age groups were stratified in relation with the age at the moment of the Chernobyl event. A database was obtained (Microsoft Excel) and statistical correlations were applied. In the studied period, 1159 patients were diagnosed: 968 females and 191 males, distributed by region, with the highest addressability in Iasi (529), followed by neighboring counties. Age distribution displayed that most of the thyroid cancers were in the range 4060 years old (50.94%), followed by 60–80 years old (32.41%). Most patients were diagnosed with papillary carcinoma 63.10%, then follicular 14.7%, medullary 6.74% and undifferentiated 1.02%. Romania was in the vicinity of the radioactive cloud at Chernobyl fallout, so we must deliberate whether the increased incidence of thyroid cancer in the age group 40–60 years is associated with radiogenicity (iodine 131) given the fact that over has 35 years and the half-life of other radioisotopes like Caesium-137 and Strontium -90 is completed.

Gene Expression Profiles for Radiation-induced Thyroid Cancer

2011 ◽  
Vol 23 (4) ◽  
pp. 282-288 ◽  
Author(s):  
C. Maenhaut ◽  
V. Detours ◽  
G. Dom ◽  
D. Handkiewicz-Junak ◽  
M. Oczko-Wojciechowska ◽  
...  
Keyword(s):  
Gene Expression ◽  
Thyroid Cancer ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Radiation Induced

Patient Segmentation Based on Patient Loyalty

2018 ◽  
Vol 20 (4) ◽  
pp. 508-534
Author(s):  
Remedios Calero ◽  
Carlota Lorenzo ◽  
Martina G. Gallarza
Keyword(s):  
Health Care ◽  
Health Management ◽  
Health Care Financing ◽  
Secondary Data ◽  
Patient Loyalty ◽  
Health Council ◽  
Patient Segmentation ◽  
Patient Profiles ◽  
The One ◽  
The Impact

The present study aims to perform a segmentation of patients based on their loyalty behaviour. The analysis focuses on Valencia, a region in Spain that features a capitated financing and free-elective framework; such a framework is particularly suitable for this type of study because patient loyalty directly affects the system’s budget and economic viability. Using secondary data from the regional health council, the study focuses on relationships of influence and latent segmentation in answering seven research questions. The two-pronged statistical analysis is designed to analyse relationships of influence, on the one hand, and latent segmentation, on the other. Significant differences were found among the various scales analysed in the three patient loyalty behavioural models (capture, retention and desertion) for each variable within the scope, that is, subjective (gender, age and nationality) and circumstantial (size of the assigned and receiving hospital, location of the province of the assigned hospital). This finding indicates that it may be possible to develop patient profiles based on such variables to analyse different loyalty behaviours in patients and the impact of hospital communication strategies on these behaviours. Patient loyalty is essential to the viability of a capitated health care financing and management system. Likewise, identifying patient profiles would contribute to a better Valencian public health management. Accordingly, it might be applied to evaluate other health care financing systems.

Mouse one-cell embryos undergoing a radiation-induced G2 arrest may re-enter S-phase in the absence of cytokinesis

2002 ◽  
Vol 80 (7) ◽  
pp. 618-624 ◽  
Author(s):  
P Jacquet ◽  
J Buset ◽  
J Vankerkom ◽  
S Baatout ◽  
L de Saint-Georges ◽  
...  
Keyword(s):  
Calyculin A ◽  
Embryonic Cells ◽  
G2 Arrest ◽  
Cell Stage ◽  
Chromosome Fragments ◽  
X Irradiation ◽  
Radiation Induced ◽  
Mouse Zygotes ◽  
The One

PCC (premature chromosome condensation) can be used for visualizing and scoring damage induced by radiation in the chromatin of cells undergoing a G1 or G2 arrest. A method involving the fusion of irradiated single embryonic cells with single MI oocytes was used to induce PCC in mouse zygotes of the BALB/c strain, which suffer a drastic G2 arrest after X-irradiation (dose used 2.5 Gy). Other G2-arrested embryos were exposed in vitro to the phosphatase inhibitor calyculin A. Both methods furnished excellent chromosome preparations of the G2-arrested embryos. The mean number of chromosome fragments did not change significantly during G2 arrest, suggesting that zygotes of this strain are unable to repair DNA damage leading to such aberrations. Forty to fifty percent of the irradiated embryos were unable to cleave after G2 arrest and remained blocked at the one-cell stage for a few days before dying. PCC preparations obtained from such embryos suggested that about 30% of them had undergone a late mitosis not followed by cytokinesis and had entered a new DNA synthesis. These results are discussed in the light of recent observations in irradiated human cells deficient in the p53/14-3-3sigma pathway.Key words: PCC, embryo, oocyte, calyculin A, G2 arrest, cytokinesis.

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