Donor-Derived Viral Specific T-cells (VSTs) for Prophylaxis Against Viral Infections After Allogeneic Stem Cell Transplant

2019 ◽  
Author(s):  
Keyword(s):  
T Cells ◽  
Stem Cell ◽  
Stem Cell Transplant ◽  
Viral Infections ◽  
Cell Transplant ◽  
Allogeneic Stem Cell Transplant

scholarly journals Hexaviral Specific T-Cells Used for Prophylaxis and Treatment of Viral Infections in Patients Post Stem Cell Transplant

2019 ◽  
Vol 25 (3) ◽  
pp. S337
Author(s):  
Katherine M. Harris ◽  
Patrick J. Hanley ◽  
Nan Zhang ◽  
Gelina M. Sani ◽  
Haili Lang ◽  
...  
Keyword(s):  
T Cells ◽  
Stem Cell ◽  
Stem Cell Transplant ◽  
Viral Infections ◽  
Cell Transplant

scholarly journals Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study

Blood ◽  
2013 ◽  
Vol 122 (17) ◽  
pp. 2965-2973 ◽  
Author(s):  
Conrad Russell Y. Cruz ◽  
Kenneth P. Micklethwaite ◽  
Barbara Savoldo ◽  
Carlos A. Ramos ◽  
Sharon Lam ◽  
...  
Keyword(s):  
T Cells ◽  
Stem Cell ◽  
B Cell ◽  
Stem Cell Transplant ◽  
Phase 1 ◽  
Cell Transplant ◽  
Allogeneic Stem Cell Transplant ◽  
B Cell Malignancies ◽  
Phase 1 Study ◽  
Key Points

Key Points Allogeneic CD19-CAR VSTs are well tolerated by patients with relapsed B-cell malignancies post-HSCT. At periods of CD19-CAR VST persistence, these cells demonstrate antitumor activity.

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