Treatment of Cardiovascular Disease With Low Dose Rivaroxaban in Advanced Chronic Kidney Disease

Author(s):  
2012 ◽  
Vol 43 (6) ◽  
pp. 451-456 ◽  
Author(s):  
Cheng-Jui Lin ◽  
Hsuan-Liang Liu ◽  
Chi-Feng Pan ◽  
Chih-Kuang Chuang ◽  
Thanasekaran Jayakumar ◽  
...  

Heart ◽  
2017 ◽  
Vol 103 (23) ◽  
pp. 1880-1890 ◽  
Author(s):  
Iryna Schlackow ◽  
Seamus Kent ◽  
William Herrington ◽  
Jonathan Emberson ◽  
Richard Haynes ◽  
...  

PLoS ONE ◽  
2014 ◽  
Vol 9 (8) ◽  
pp. e104179 ◽  
Author(s):  
Ae Jin Kim ◽  
Hye Jin Lim ◽  
Han Ro ◽  
Kwang-Pil Ko ◽  
Song Yi Han ◽  
...  

2019 ◽  
pp. 2-3

Impaired phosphate excretion by the kidney leads to Hyperphosphatemia. It is an independent predictor of cardiovascular disease and mortality in patients with advanced chronic kidney disease (stage 4 and 5) particularly in case of dialysis. Phosphate retention develops early in chronic kidney disease (CKD) due to the reduction in the filtered phosphate load. Overt hyperphosphatemia develops when the estimated glomerular filtration rate (eGFR) falls below 25 to 40 mL/min/1.73 m2. Hyperphosphatemia is typically managed with oral phosphate binders in conjunction with dietary phosphate restriction. These drugs aim to decrease serum phosphate by binding ingested phosphorus in the gastrointestinal tract and its transformation to non-absorbable complexes [1].


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