Efficacy of Cryotherapy Combined With Intralesional Tuberculin PPD Versus Intralesional Tuberculin PPD in Treatment of Multiple Common Warts

Objective.To investigate the clinical efficacy and safety of intralesional injection of 2% zinc sulfate solution in the treatment of common warts.Patients and Methods.One hundred and twenty patients (78 females and 42 males) aged 5–55 years with 225 common warts participated in this prospective monocentric randomized study. All lesions were treated with intralesional injection of 2% zinc sulfate.Results.From 225 warts injected, 135 warts (60%) cured from the first session, 51 warts (22.67%) cured from the second session, and 12 warts (5.33%) cured from the third session. There is no significant relation between improvement and patient’s ages, duration, or number of warts (P<0.05). All patients complained from pain during injection, and all treated lesions showed redness, tenderness, and swelling in the first 3 days after injection. Late complications were postinflammatory hyperpigmentation in 90 patients (75%), scaring in 9 patients (7.5%), and ulceration in 3 patients (2.5%). Recurrence occurred in 3 lesions (1.33%).Conclusion.The clinical data indicate that intralesional injection of 2% zinc sulfate is an effective maneuver in the treatment of common warts; however, its associated complications limit its use.

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Common Warts

Close Encounters of the Microbial Kind ◽

10.1007/978-3-030-56978-5_9 ◽

2021 ◽

pp. 147-156

Author(s):

Michael Wilson ◽

Philippa J. K. Wilson

Keyword(s):

Common Warts

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Management of Root Like Man: Case from Gatot Soebroto, The Indonesian Army National Hospital

Jurnal Plastik Rekonstruksi ◽

10.14228/jpr.v1i3.63 ◽

1970 ◽

Vol 1 (3) ◽

Author(s):

Ali Sundoro ◽

Laureen Supit ◽

Asrofi S. Surachman ◽

Harun Adam ◽

Budiman Budiman ◽

...

Keyword(s):

Hpv Infection ◽

Treatment Modalities ◽

Team Approach ◽

Body Parts ◽

Papilloma Virus ◽

Verruca Vulgaris ◽

Common Warts ◽

Cutaneous Warts

Background: Patients and clinicians experience the frustration of cutaneous viral warts due to human papilloma virus (HPV) infection. Verruca vulgaris, the common warts, appear in various forms at different body sites. Over 118 types of papilloma virus have been identified. The most common cutaneous warts are caused by types 1, 2, 4, 27, 57, and 19 HPV. The rare cases of generalized warts around the world are suspected to be caused by type 2 HPV. There are many treatment modalities for this disease but none is 100% effective yet. Patient and Method :We report a 39-year-old male with generalized warts on various body parts (scalp, forehead, trunk, arms, lower leg and foot). The team consist of plastic surgeons, dermatologist, psychiatrist, pathologist, medical rehabilitationist, and internist. The treatment goals were to remove all warts, prevent recurrence of the disease, and improve the immunological status of the patient. Serial excisions were performed and closure attained using a combination of primary sutures, skin grafts (split- and full-thickness), and skin flaps. 5 Fluorouracil was administered on the raw surfaces before closure. Staged excisions were performed 11 times, with 3-4 weeks interval over a1-year period. Interferon and cimetidine injection were also given to augment the immune system.Results : All lesions were successfully excised and reconstructed. On a few fingers, hypertrophic scar and minor contracture ensued after closure by skin graft. Patient is able to carry out daily living activities independently. Patient was profoundly delighted and his quality of life improved.Summary : Management of a rare generalized verruca vulgaris through a team approach, by multiple staged excision, 5-FU application before defect closure, combined with antiviral therapy, proved effective in a case.

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Evaluation of therapeutic effectiveness of vitamin D3 injections in common warts in a tertiary care centre

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20192134 ◽

2019 ◽

Vol 5 (3) ◽

pp. 462

Author(s):

Sushmalatha Banoth

Keyword(s):

Vitamin D3 ◽

Normal Saline ◽

Tertiary Care ◽

Treatment Session ◽

Tertiary Care Centre ◽

Cutaneous Manifestations ◽

Multiple Modalities ◽

Common Warts ◽

Group A ◽

Group B

Background: Warts or verrucae are the benign cutaneous manifestations caused by human papilloma virus. The treatment of wart possess a therapeutic challenge, as a result multiple modalities are existing for the treatment of cutaneous warts, which is cumbersome and may result in cosmetic disfigurement, chances of recurrences. The aim of the present study was to determine the resolution of common warts in response to vitamin D3 injections and to compare the resolution of common warts in the group receiving vitamin D3 with placebo group receiving normal saline.Methods: A total of 26 patients were enrolled and divided into Group A- received lesional injection of 0.2 ml vitamin D3 every 3 weeks for 3 months for the improvement in the size of warts. Group B- received 0.2 ml of normal saline injections as a control. The maximum of three sessions were carried in both groups. Clinical assessment was done by photographic evaluation at baseline, before each treatment session, and after completion of treatment.Results: In group A, 76.92% (10) of the patients showed complete clearance of wart with vitamin D3 injection, while in group B 8% (1) of patients with normal saline showed partial response. This therapy was well tolerated except for the minimal side effects like pain, redness and swelling at the site of injection.Conclusions: Intralesional Vit D3 injections may be a treatment option for warts, which has a good cosmetical acceptance and simple, well tolerated easily administrated in outpatient clinic rather than conventional treatment.

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Detection and Typing of Human Papillomavirus in Cutaneous Common Warts by Multiplex Polymerase Chain Reaction

Journal of Life Science ◽

10.5352/jls.2011.21.7.947 ◽

2011 ◽

Vol 21 (7) ◽

pp. 947-952

Author(s):

Soon-Yong Choi ◽

Jong-Ho Lim ◽

Eun-Jung Kim ◽

Hei-Sung Kim ◽

Beom-Joon Kim ◽

...

Keyword(s):

Polymerase Chain Reaction ◽

Human Papillomavirus ◽

Multiplex Polymerase Chain Reaction ◽

Chain Reaction ◽

Common Warts ◽

Polymerase Chain

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A comparative Study Between Needling and Homologous Autoimplantation Techniques in Treatment of Multiple Plantar Warts

QJM ◽

10.1093/qjmed/hcab093.008 ◽

2021 ◽

Vol 114 (Supplement_1) ◽

Author(s):

Nermeen Samy Abdel Fattah ◽

Rania Mahmoud Elhusseiny ◽

Aml Magdy Darahem

Keyword(s):

Treatment Response ◽

De Novo ◽

Response To Treatment ◽

Clinical Appearance ◽

Skin Contact ◽

Common Warts ◽

Significant Difference ◽

Assess Treatment Response ◽

Skin To Skin ◽

Plantar Warts

Abstract Background Warts are a common dermatologic complaint resulting from infection with HPV which spread by direct skin-to-skin contact or by autoinoculation. The clinical appearance of warts is variable depends on the type of HPV involved and the site of infection. There are various types of viral warts including common warts, plantar warts, plane warts and genital warts, usually diagnosis of warts is made through clinical examination of the lesions and no laboratory investigations are required. Objective To compare between the therapeutic efficacy and safety of needling versus homologous autoimplantation techniques in treatment of multiple plantar warts and assess their recurrence rate. Patients and Methods Our study included 40 patients with multiple de novo planter warts(3 -10 warts) of (>1 and <3 years duration) divided into 2 groups, 20 patients per group, one group subjected to autoimplantation of wart tissue and the other subjected to needling procedure. Follow up of studied patients was assessed by physician after 2,8 and 12 weeks of procedure through clinical and dermoscopic examination to assess treatment response and after 16 weeks to assess recurrence Results Results of our study reported that there was high statistically significant difference between the 2 studied groups as regard response to treatment after 12 weeks being higher among autoimplantation group (p = 0.001). Moreover, there were no significant relations between treatment response of both patient groups and each of gender, age of patients, number of warts and duration of lesions. Conclusion Autoimplantation technique is more effective and less painful than needling procedure in treatment of multiple plantar warts (both manipulated and remote warts). No significant relations were found between treatment response of either techniques and demographic or clinical characteristics of studied patients.

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