scholarly journals Management of Root Like Man: Case from Gatot Soebroto, The Indonesian Army National Hospital

1970 ◽  
Vol 1 (3) ◽  
Author(s):  
Ali Sundoro ◽  
Laureen Supit ◽  
Asrofi S. Surachman ◽  
Harun Adam ◽  
Budiman Budiman ◽  
...  

Background: Patients and clinicians experience the frustration of cutaneous viral warts due to human papilloma virus (HPV) infection. Verruca vulgaris, the common warts, appear in various forms at different body sites. Over 118 types of papilloma virus have been identified. The most common cutaneous warts are caused by types 1, 2, 4, 27, 57, and 19 HPV. The rare cases of generalized warts around the world are suspected to be caused by type 2 HPV. There are many treatment modalities for this disease but none is 100% effective yet. Patient and Method :We report a 39-year-old male with generalized warts on various body parts (scalp, forehead, trunk, arms, lower leg and foot). The team consist of plastic surgeons, dermatologist, psychiatrist, pathologist, medical rehabilitationist, and internist. The treatment goals were to remove all warts, prevent recurrence of the disease, and improve the immunological status of the patient. Serial excisions were performed and closure attained using a combination of primary sutures, skin grafts (split- and full-thickness), and skin flaps. 5 Fluorouracil was administered on the raw surfaces before closure. Staged excisions were performed 11 times, with 3-4 weeks interval over a1-year period. Interferon and cimetidine injection were also given to augment the immune system.Results : All lesions were successfully excised and reconstructed. On a few fingers, hypertrophic scar and minor contracture ensued after closure by skin graft. Patient is able to carry out daily living activities independently. Patient was profoundly delighted and his quality of life improved.Summary : Management of a rare generalized verruca vulgaris through a team approach, by multiple staged excision, 5-FU application before defect closure, combined with antiviral therapy, proved effective in a case.

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Preisy G. I. Tampi ◽  
Ferra O. Mawu ◽  
Nurdjannah J. Niode

Abstract: Verruca vulgaris (common warts) is a benign proliferation of squamous epithelium caused by Human papillomavirus (HPV) infection, especially type 2 and 1. Verruca vulgaris can occur at any age, but more often among children and young adults. Warts are spread by direct or indirect contact. The lesions appear most commonly in areas affected by trauma such as the hands, fingers, elbows, and knees, albeit, they can occur in other places. This study aimed to determine the profile of verruca vulgaris in Dermatovenereology Clinic of Prof. Dr. R. D. Kandou Hospital Manado period January – December 2013. This was a retrospective study based on gender, age, occupation, location of the lesion, and therapy. The results showed that of 4099 new cases there were 43 cases of verruca vulgaris (1.05%), most were females (51.16%), and aged 5-14 years (30.22%). They were commonly students (32.56%), the location of lesion at the upper extremity (32.56%), and the treatment of the lesion with electrical surgery (93.02%). Keywords: verruca vulgaris Abstrak: Veruka vulgaris (common warts atau kutil) adalah proliferasi jinak epitel skuamous yang disebabkan oleh infeksi Human Papillomavirus (HPV), terutama tipe 2 dan 1. Veruka vulgaris dapat menyerang semua kelompok usia, tetapi lebih sering pada anak dan dewasa muda. Penyebaran virus ini dapat melalui kontak langsung maupun secara tidak langsung. Veruka sering timbul pada daerah yang terkena trauma seperti tangan, jari, siku dan lutut, namun dapat timbul di mana saja pada kulit. Penelitian ini bertujuan untuk mengetahui profil veruka vulgaris di Poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado periode Januari-Desember 2013. Penelitian ini bersifat deskriptif retrospektif dengan variabel jenis kelamin, umur, pekerjaan, lokasi lesi, dan penatalaksanaan. Hasil penelitian menunjukkan bahwa dari 4099 kasus baru terdapat 43 kasus veruka vulgaris (1,05%), terbanyak ialah pasien perempuan (51,16%), dengan kelompok umur 5-14 tahun (30,22%), terbanyak pada siswa (32,56%), lokasi lesi ekstremitas atas (32,56%), dan penatalaksanaan lesi dengan bedah listrik (93,02%).Kata kunci: veruka vulgaris


1988 ◽  
Vol 101 (3) ◽  
pp. 537-546 ◽  
Author(s):  
K. Steele ◽  
P. V. Shirodaria ◽  
H. Pfister ◽  
B. Pollock ◽  
P. Fuchs ◽  
...  

SUMMARYThree hundred and seventy-six patients attending their general practitioner with cutaneous warts at five health centres in Northern Ireland were screened for human papilloma virus (HPV) types 1 and 2 IgM antibody using an indirect immunofluorescence test. Eighty-eight (23·4%) patients were positive for HPV type 1 IgM and 156 (41·5%) for HPV type 2 IgM. HPV 1 IgM antibody was significantly more likely to be associated with plantar warts than warts elsewhere (P 0·0001). HPV 2 IgM was present in 45 (34·1%) patients with plantar warts and 99 (45·6%) patients with warts at other sites (P=0·1). Evidence of multiple infection by HPV types 1 and 2 was demonstrated by the finding of HPV 1 and 2 IgM antibodies in the sera of 16 (4·3%). HPV 4 was found in only 1 out of 30 biopsies and HPV 4 IgM was undetectable in 50 randomly chosen sera.


Author(s):  
Lee Kian Khoo ◽  
Low Eng Chai ◽  
Bishwa Prakash Bhattarai ◽  
Dinesh Rokaya ◽  
Boonaur Yongvanichakorn ◽  
...  

AbstractVerruca vulgaris, also known as common warts, is most often seen on the skin of hands and feet. Human papilloma virus (HPV) plays an aetiological role in the development of this lesion. Oral verruca vulgaris (OVV) may occur on the palate, buccal mucosa, and tongue. Although asymptomatic and benign, HPV has been linked to squamous cell carcinoma in the oral cavity and oropharyngeal areas. Therefore, prompt surgical removal of OVV is warranted. We report a case of a OVV in a 48-year-old male patient on palate. The lesion was a white nonscrapable lesion in the middle of a torus palatinus. Excisional biopsy was done together with surgical removal of torus palatinus. Histopathological analysis confirmed the diagnosis of OVV.


2012 ◽  
Vol 30 (3) ◽  
pp. 151-158 ◽  
Author(s):  
Lubna Khondker ◽  
Md Obaidur Rahman Shah ◽  
Md Shirajul Shirajul Islam Khan

Verruca or warts are common significant cause of cosmetic concern and frustration of the patient. Social activities may  be affected. Verruca are formed by benign proliferations of the skin and mucosa that are caused by infection with  Human papilloma virus (HPV). These viruses do not produce acute signs or symptoms but induce a slow, focal expansion of epithelial cells. There are 100 types of Human papilloma virus (HPV). The natural history of common warts is for most of them to spontaneously resolve. But lesions are sometime uncomfortable. Warts typically continue to increase in size and distribution and may become more resistant to treatment over time. A significant  proportion of women with genital HPV infection develops  low-grade cervical lesions. Most of these low-grade lesions regress spontaneously; one study suggests that  approximately 15 percent progress to high-grade cervical  lesions within two years. High-grade cervical lesions have  a strong malignant potential; one study found that about one-third of high-grade lesions progress to cancer within ten years. DOI: http://dx.doi.org/10.3329/jbcps.v30i3.12465 J Bangladesh Coll Phys Surg 2012; 30: 151-158


2017 ◽  
Vol 9 (2) ◽  
pp. 102-107 ◽  
Author(s):  
Ivan Robert Bristow ◽  
Christopher Webb ◽  
Michael Roger Ardern-Jones

Plantar warts, caused by the human papilloma virus (HPV), are a commonly encountered condition presenting in clinic. In adults, an array of various therapies exists, frequently with modest results particularly with plantar lesions. Microwaves have had limited uses for medical purposes. Recently a new portable microwave device has been approved for the treatment of skin lesions. Prior research has demonstrated immuno-stimulatory effects against HPV infection. We report the application of a novel portable medical microwave unit to treat a long-standing plantar wart which had failed to respond to other treatment modalities.


2012 ◽  
Vol 08 (02) ◽  
pp. 84
Author(s):  
Cynthia Fritschi ◽  
Anne M Fink ◽  
◽  

Patients with type 2 diabetes often experience fatigue, which impacts their self-care and quality of life. There are few data supporting a relationship between fatigue and glucose homeostasis, but fatigue in type 2 diabetes has been associated with higher body mass index (BMI), depression, physical inactivity, sleep disturbances, and chronic low-grade inflammation. Although links between fatigue and inflammation are documented in other disease populations, little is known about inflammatory mechanisms specific to type 2 diabetes and associated treatment modalities for type 2 diabetes-related fatigue. Herein we review existing knowledge about fatigue in type 2 diabetes and potential pharmacologic and behavioral therapies.


Author(s):  
Meenu Vijayan ◽  
Rose Jose ◽  
Sruthy Jose ◽  
Suja Abraham ◽  
Jintu Joy

Objective: The aim was to study the vision-related quality of life (QOL) for diabetic retinopathy (DR) among patients with Type 2 diabetes and to assess the direct medical cost of different treatment modalities. Methods: It was based on an individual-based analysis of QOL before and after the treatment for DR. The main objective of the study was to compare QOL between patients based on the different treatment modalities using vision function questionnaire (VFQ)-25, to evaluate the direct medical cost for DR patients undergoing different treatment modalities and to compare the cost and QOL of different treatment modalities in samples with non-proliferative DR (NPDR)/proliferative diabetic retinopathy (PDR) macular edema. The population included were patients with Type 2 diabetes with NPDR, with clinically significant macular edema and PDR, patients diagnosed to have diabetes above 5-year duration, adult patients, ocular pain those who are on regular follow-up and those who are willing to be a part of study. A total of 256 patients were selected out, of which 141 patients were satisfied the study criteria and participated in the study. Data relevant to the voice-related QOL study were obtained and recorded using VFQ-25 questionnaire. Other data relevant to the study were obtained and recorded in a semistructured data collection form by interviewing the patient or their caregivers and by direct examination of patient’s medical record. Expenditure was calculated in Indian Rupees. Results: After comparing the baseline QOL with QOL after treatment, it was found that the overall QOL of the study samples in accordance with the treatment undergone was found to be improved. The overall QOL had improved after the treatment for all samples and major improvement was seen on dependency, social functioning (SF), and mental health (MH). Conclusion: The overall QOL had improved after the treatment for all samples and major improvement were seen on dependency, SF, and MH. In conclusion, the study analyzed that intravitreal bevacizumab therapy is the cheapest one and with the comparatively same clinical outcome when compared with intravitreal ranibizumab therapy for macular edema cases in patients with NPDR and PDR.


2010 ◽  
Vol 8 (2) ◽  
pp. 80 ◽  
Author(s):  
Cynthia Fritschi ◽  
Anne M Fink ◽  
◽  

Patients with type 2 diabetes often experience fatigue, which impacts their self-care and quality of life. There are few data supporting a relationship between fatigue and glucose homeostasis, but fatigue in type 2 diabetes has been associated with higher body mass index (BMI), depression, physical inactivity, sleep disturbances and chronic low-grade inflammation. Although links between fatigue and inflammation are documented in other disease populations, little is known about inflammatory mechanisms specific to type 2 diabetes and associated treatment modalities for type 2 diabetes-related fatigue. Herein we review existing knowledge about fatigue in type 2 diabetes and potential pharmacological and behavioural therapies.


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