scholarly journals Mindfulness Based Therapy in Cancer Patients: Meta-Analysis

2021 ◽  
Vol 6 (3) ◽  
pp. 329-338
Author(s):  
Kamna Yadav ◽  
Samanta Puspak Kumar Jena
Keyword(s):  
Meta Analysis ◽  
Well Being ◽  
Medium Effect ◽  
Anxiety And Depression ◽  
Controlled Trials ◽  
Reference List ◽  
Random Effects Model ◽  
Randomized Controlled ◽  
Journal Content ◽  
Effect Size Calculation

Evidence suggested that mindfulness-based techniques have been effective in increasing psychological well-being. The present meta-analytic study aimed to examine the effects of mindfulness-based programmes on anxiety, and depression in cancer infected and survivors. Improvement in mindfulness across groups were also studied. Using various search items (e.g., MBCT, MBSR, Cancer). A systematic search of the electronic databases, reference list, and journal content lists were conducted from June 2011 to June 2020. Fourteen randomized controlled trials (N = 1831) evaluating effect of mindfulness in reducing anxiety and depression in cancer, measuring at pre-and-post interventions were included in this study. Random effects model was utilized for effect-size calculation. Interventions were between 5-8 weeks, with majority of participants been female (98.79%). Significant medium effect was observed for anxiety (g = 0.34) and depression (g = 0.32) with moderate heterogeneity and higher for mindfulness (g = 1.061) with high heterogeneity. Publication bias was not observed. Mindfulness has substantial effects in reducing anxiety and depression in cancer infected and survivors.

scholarly journals Resource Group Assertive Community Treatment (RACT) as a Tool of Empowerment for Clients with Severe Mental Illness: A Meta-Analysis

2012 ◽  
Vol 8 (1) ◽  
pp. 144-151 ◽  
Author(s):  
Tommy Nordén ◽  
Ulf Malm ◽  
Torsten Norlander
Keyword(s):  
Randomized Controlled Trials ◽  
Assertive Community Treatment ◽  
Meta Analysis ◽  
Well Being ◽  
Community Treatment ◽  
Medium Effect ◽  
Controlled Trials ◽  
Psychiatric Diagnoses ◽  
Randomized Controlled ◽  
Resource Group

The aim of the current meta-analysis was to explore the effectiveness of the method here labeled Resource Group Assertive Community Treatment (RACT) for clients with psychiatric diagnoses as compared to standard care during the period 2001 – 2011. Included in the meta-analysis were 17 studies comprising a total of 2263 clients, 1291 men and 972 women, with a weighted mean age of 45.44 years. The diagnoses of 86 % of the clients were within the psychotic spectrum while 14 % had other psychiatric diagnoses. There were six randomized controlled trials and eleven observational studies. The studies spanned between 12 and 60 months, and 10 of them lasted 24 months. The results indicated a large effect-size for the ”grand total measure” (Cohen´sd= 0.80). The study comprised three outcome variables: Symptoms, Functioning, and Well-being. With regard to Symptoms, a medium effect for both randomized controlled trials and non-randomized studies was found, whereas Functioning showed large effects for both types of design. Concerning Well-being both large and medium effects were evident. The conclusions of the meta-analysis were that the treatment of clients with Resource Group Assertive Community Treatment yields positive effects for clients with psychoses and that the method may be of use for clients within the entire psychiatric spectrum.

scholarly journals M103. PSYCHOLOGICAL ONLINE INTERVENTION FOR PSYCHOSIS: A SYSTEMATIC REVIEW AND META-ANALYSIS

2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S174-S174
Author(s):  
Rebeca Pardo Cebrián ◽  
Eduardo González-Fraile ◽  
Teresa Sánchez-Gutiérrez ◽  
Sara Barbeito ◽  
Belén Fernández-Castilla ◽  
...  
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Randomised Trial ◽  
Online Intervention ◽  
Well Being ◽  
Psychotic Symptoms ◽  
Psychological Interventions ◽  
Controlled Trials ◽  
Randomized Controlled

Abstract Background Although the use of technological advances in psychiatric treatment is relatively recent, the availability and sophistication of technologies are growing, research on psychological interventions for patients with psychosis has incorporated the use of various electronic applications, social networks, and other similar tools to provide new methods/routes of communication between therapists and patients. This new therapeutic approach may provide patients with personalized, flexible, and evidence-based interventions in their communities and even in their own homes. The aim of this study is reviewing the scientific literature about the use of online intervention for patients with psychosis to show the current state of online intervention and asses the effectiveness of these treatments. Methods The review was conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We have identified articles from Pubmed and Medline databases. We included all randomized controlled trials designed to test the efficacy of the online intervention or web-based intervention to patients with psychosis. We excluded observational trials, non-randomised trial and protocol study. Studies with RCT design and the participants must not have more than 5 to 10 years of evolution since the diagnosis, and the papers have been published between 2010 and 2019, in English language. The researchers independently assessed the articles and the discrepancies were resolved by consensus. Results We presented data about all randomized controlled trials of online interventions/ e-Health interventions/ App-mobile based and/or computer based intervention programs than were specifically designed for people with first episode psychosis or psychotic symptoms that had measured changes in functioning, quality of life or positive/negative symptoms. As unique treatment or as a complementary treatment with other psychological or psychopharmacology intervention. Discussion Online psychological interventions can play an important role in the well-being of people with schizophrenia. The strengths and limitations of our systematic review and meta-analysis will be discussed.

Randomized controlled trials (RCTs) examining continuous (CS) versus intermittent strategies (IS) of delivering systemic treatment (Tx) for untreated metastatic colorectal cancer (mCRC): A meta-analysis from the Cancer Care Ontario program in evidence-based care.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 3534-3534 ◽  
Author(s):  
Scott R. Berry ◽  
Roxanne Cosby ◽  
Timothy R. Asmis ◽  
Kelvin K. Chan ◽  
Nazik Hammad ◽  
...  
Keyword(s):  
Systemic Treatment ◽  
Meta Analysis ◽  
Sensitivity Analyses ◽  
Controlled Trials ◽  
Evidence Based ◽  
Random Effects Model ◽  
Randomized Controlled ◽  
Hazard Ratios ◽  
Evidence Based Care ◽  
Review Manager

3534 Background: Given the varying impact on efficacy demonstrated in individual RCTs of CS vs IS of delivering systemic Tx for mCRC, a meta-analysis of the available RCTs was performed. Methods: RCTs that compared a CS versus IS of delivering systemic Tx were identified by a systematic search (MEDLINE, EMBASE and ASCO and ESMO proceedings) and review. The results of identified trials were clinically homogeneous (Table) so the data was pooled using Review Manager software (RevMan 5.2). Overall survival (OS) hazard ratios were extracted directly from the most recently reported trial results. A random effects model was used for all pooling. Results: 10 RCTs were identified (n= 4,296). After an induction period, the maintenance Tx patients received during the IS was: none (5 trials, n=2,562), fluoropyrimidine (F) (2 trials, n=759), biologic (B) (2 trials, n=852), F+B (1 trial, n=123). Results of the meta-analysis are summarized in the Table (HR>1 favors CS). Sensitivity analyses performed demonstrate results are robust independent of the induction or maintenance Tx used. QOL (data from 2 trials) was either the same in both arms (single Tx induction trial with no maintenance Tx, n=354) or improved in the IS arm (combination tx induction trial with no maintenance Tx, n=1,630). Conclusions: IS of delivering systemic Tx for mCRC do not result in a statistically significant reduction in OS compared to a CS of delivery whether or not maintenance therapy is included. QOL is the same or better with an IS. [Table: see text]

scholarly journals Selenium Supplementation for Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Yaofu Fan ◽  
Shuhang Xu ◽  
Huifeng Zhang ◽  
Wen Cao ◽  
Kun Wang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Adverse Events ◽  
Autoimmune Thyroiditis ◽  
Literature Search ◽  
Meta Analysis ◽  
Well Being ◽  
Selenium Supplementation ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Close Relationship

Many studies have reported that selenium (Se) has a close relationship with autoimmune thyroiditis (AIT). The therapeutic effect of Se supplementation in AIT treatment remains unclear. The objective of the present study was to determine the efficacy of Se supplementation for the treatment of AIT. A structured literature search was undertaken to identify all randomized controlled trials conducted in patients with AIT receiving Se supplementation or placebo. Nine studies enrolling a total of 787 patients were included. The results showed that Se supplementation with duration 6 months significantly dropped the TPOAb titers but did not decrease the TgAb titers. Patients assigned to Se supplementation for 12-month duration showed significantly lower TPOAb titers and TgAb titers. Patients after Se supplementation had a higher chance to improve the mood or well-being compared with controls. Se supplementation is associated with a significant decrease in TPOAb titers at 6 and 12 months; meanwhile, the TgAb titers can be dropped at 12 months. After Se supplementation treatment, patients had a higher chance to improve the mood without significant adverse events.

scholarly journals Effects of Tea Consumption on Anthropometric Parameters, Metabolic Indexes and Hormone Levels of Women with Polycystic Ovarian Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

2021 ◽  
Vol 12 ◽  
Author(s):  
Wenjuan Shen ◽  
Yujia Pan ◽  
Bao Jin ◽  
Zongyu Zhang ◽  
Tianjiao You ◽  
...  
Keyword(s):  
Systematic Review ◽  
Body Weight ◽  
Randomized Controlled Trials ◽  
Green Tea ◽  
Random Effects ◽  
Meta Analysis ◽  
Biomedical Literature ◽  
Controlled Trials ◽  
Random Effects Model ◽  
Randomized Controlled

ObjectiveOur aim was to conduct a systematic review and meta-analysis to assess the effectiveness and safety of tea supplements for patients with polycystic ovary syndrome (PCOS).MethodsWe conducted searches of the published literature in PubMed, EMBASE, Cochrane Library, Web of Science, Chinese Biomedical Literature Database, Chinese National Knowledge Infrastructure (CNKI), VIP database, and Wanfang Database in 1985 to September 2021. Data from randomized controlled trials (RCTs) were obtained to assess the effects of tea versus placebo in women with PCOS. Weighted mean differences (WMDs) were pooled using a random-effects model or risks ratios (RRs) using a random-effects model.ResultsSix RCTs (235 participants) were included in our systematic review. Tea supplements as adjuvant therapy led to greater improvement in body weight (WMD −2.71, 95% CI −4.95 to −0.46, P = 0.02, I2 = 0%), fasting blood glucose (FBG: WMD −0.40, 95% CI −0.59 to −0.20, P < 0.0001, I2 = 0%) and fasting insulin (FINS: WMD −3.40, 95% CI −4.76 to −2.03, P < 0.00001, I2 = 0%) when compared with placebo. There were no significant differences of body mass index, waist circumference, hip circumference, waist-to-hip ratio (WHR), body fat rate, total testosterone, free testosterone (FT), dehydroepiandrosterone, luteinizing hormone or follicular-stimulating hormone (FSH) between the two groups. In addition, subgroup analysis suggested that green tea was effective on body weight, FINS, FBG, FT, and FSH, and herbal tea can also reduce FT levels, tea supplements had a significant impact on FBG and FSH in trials with intervention duration ≥ 3 months, and intervention lasting less than 3 months can improve FINS. Tea had significant effect on reducing WHR, FBG and FSH in Asian PCOS patients, but not in Caucasians. And there was no statistically significant effect of tea on weight and FINS in Asians, but it was effective for Caucasian participants. Compared with placebo, tea supplements did not cause significant adverse reactions (RR 1.45, 95% CI 0.30 to 6.90, P = 0.65, I2 = 0%).ConclusionThis meta-analysis suggests that consumption of tea supplementation in women with PCOS could significantly decrease the levels of FBG and FINS as well as reduce body weight. Especially green tea, not only has the above effects, but also has a significant effect on improving a variety of reproductive hormone indexes. Furthermore, tea supplementation is a relatively safe therapy for PCOS patients. Systematic Review RegistrationPROSPERO https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=212755, identifier CRD42021249196.

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