scholarly journals Prevalence of EGFR Mutations and Clinico-Pathological Characteristics of Chilean Lung Cancer Patients

2019 ◽  
Vol 20 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Roger Gejman ◽  
Sergio Gonzalez ◽  
Matias Munoz Medel ◽  
Bruno Nervi ◽  
Cesar Sanchez ◽  
...  

2013 ◽  
Vol 8 (3) ◽  
pp. 295-300 ◽  
Author(s):  
Niki Karachaliou ◽  
Carlota Costa ◽  
Ana Gimenez-Capitan ◽  
Miguel Angel Molina-Vila ◽  
Jordi Bertran-Alamillo ◽  
...  






2017 ◽  
Vol 28 ◽  
pp. v574 ◽  
Author(s):  
B. Park ◽  
D-E. Ryu ◽  
H.K. Kim ◽  
J.H. Cho ◽  
J. Lee ◽  
...  


2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e18038-e18038
Author(s):  
Baohui Han ◽  
Yu Dong ◽  
Yanwei Zhang ◽  
Bo Jin

e18038 Background: Background: As the non-smoking Asian patients with adenocarcinoma of the EGFR gene tend to have higher mutation rate, and serum CEA levels in patients with lung cancer, especially adenocarcinoma, high expression in many recent years, studies have also found that serum CEA levels in EGFR-changes before and after TKI therapy efficacy and treatment are closely related. However, whether serum CEA level and EGFR gene mutations is a correlation between two biomarkers. This study attempts to explore its relevance between EGFR gene mutations and analysis of serum CEA levels in non-smoking patients with lung cancer and it’s various clinical and pathological features. Methods: 84 cases of histologically confirmed non-smoking history in newly diagnosed lung cancer patients, respectively, serum CEA levels and histological detection of EGFR gene. According to the expression level of serum CEA patients were divided into high expression and did not express two groups were compared in patients with EGFR gene mutations. Results: 58/84 cases were found with activity EGFR gene mutations, the overall mutation rate was 69.0%, serum CEA levels high expression of EGFR gene mutation was significantly higher than non-expression group (serum CEA levels were <5ng/ml, ≥ 5ng/ml <20ng/ml, ≥ 20ng/ml patients with EGFR gene mutations histology were 63.2%, 70.8%, 81.8%). Conclusions: Non-smoking lung cancer patients with serum CEA levels and EGFR gene mutations was positively correlated.



2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e20017-e20017
Author(s):  
Jin-Hyoung Kang ◽  
Jung-Young Shin ◽  
Jeong-Oh Kim ◽  
Min Young Kim ◽  
Kyoung Hwa Son ◽  
...  


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