The Relationship between ABO Blood Group Type and the COVID-19 Susceptibility in Qatif Central Hospital, Eastern Province, Saudi Arabia: A Retrospective Cohort Study

Objective: To investigate the association between the ABO blood group and the COVID-19 susceptibility. Material & Methods: The study is a retrospective cohort study. It included all hospitalized confirmed COVID-19 patients in Qatif central hospital, Eastern province, Saudi Arabia. Results: Our sample consists of 72 patients, we found a percentage distribution of 23.62%, 33.33%, 9.72%, and 33.33% for blood groups A, B, AB and O, respectively. Our results showed significantly increased risk for AB blood groups and significantly lower risk for the O blood group. Although there was a higher percentage distribution of the B blood group among COVID-19 patients as compared to the blood donors’ groups, this difference did not reach statistical significance. Conclusion: patients with AB blood group have higher susceptibility while patients with O blood group have lower susceptibility to COVID-19 infection. Our study has limitations and further studies are needed.

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The Relationship between ABO Blood Group Type and the COVID-19 Susceptibility in Qatif Central Hospital, Eastern Province, Saudi Arabia: A Retrospective Cohort Study

Open Journal of Internal Medicine ◽

10.4236/ojim.2020.102024 ◽

2020 ◽

Vol 10 (02) ◽

pp. 232-238 ◽

Cited By ~ 1

Author(s):

Ghada Ali Aljanobi ◽

Alya Hassan Alhajjaj ◽

Fatimah Lateef Alkhabbaz ◽

Jumana Mansour Al-Jishi

Keyword(s):

Saudi Arabia ◽

Cohort Study ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Abo Blood Group ◽

Central Hospital ◽

Eastern Province ◽

Group Type ◽

Blood Group Type ◽

The Relationship

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Gallbladder cancer in Eastern Province of Saudi Arabia: A retrospective cohort study

Annals of Medicine and Surgery ◽

10.1016/j.amsu.2018.09.020 ◽

2018 ◽

Vol 35 ◽

pp. 117-123 ◽

Cited By ~ 5

Author(s):

Mohammed Yousef Aldossary ◽

Amal Ali Alayed ◽

Samir S. Amr ◽

Shareef Alqahtani ◽

Mamdouh Alnahawi ◽

...

Keyword(s):

Saudi Arabia ◽

Cohort Study ◽

Gallbladder Cancer ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Eastern Province

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PB2310 OUTPATIENT FOLLOW-UP IS ASSOCIATED WITH REDUCED EMERGENCY DEPARTMENT VISITS IN PATIENTS WITH SICKLE CELL DISEASE – A RETROSPECTIVE COHORT STUDY FROM RIYADH, SAUDI ARABIA

HemaSphere ◽

10.1097/01.hs9.0000567708.40912.cf ◽

2019 ◽

Vol 3 (S1) ◽

pp. 1030-1031

Author(s):

R. Saleh ◽

L. Alhmaly ◽

R. Vishwakarma ◽

I. Kamran ◽

M. Damlaj ◽

...

Keyword(s):

Emergency Department ◽

Saudi Arabia ◽

Cohort Study ◽

Sickle Cell Disease ◽

Sickle Cell ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Emergency Department Visits ◽

Cell Disease

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Clinical Significance of Co-expression of Aberrant Antigens in Acute Leukemia: A Retrospective Cohort Study in Makah Al Mukaramah, Saudi Arabia

Asian Pacific Journal of Cancer Prevention ◽

10.7314/apjcp.2014.15.1.221 ◽

2014 ◽

Vol 15 (1) ◽

pp. 221-227 ◽

Cited By ~ 8

Author(s):

Nahla Ahmad Bahgat Abdulateef ◽

Manar Mohammad Ismail ◽

Hanadi Aljedani

Keyword(s):

Saudi Arabia ◽

Cohort Study ◽

Acute Leukemia ◽

Clinical Significance ◽

Retrospective Cohort Study ◽

Retrospective Cohort

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Improved Renal Recovery with Eculizumab Therapy among Children with High Prevalence of Mutation-Associated Atypical Hemolytic Uremic Syndrome: A Retrospective Cohort Study

Kidney & Blood Pressure Research ◽

10.1159/000510612 ◽

2020 ◽

Vol 45 (6) ◽

pp. 939-954

Author(s):

Abdulaziz A. Bamhraz ◽

Khawla A. Rahim ◽

Hassan Y. Faqeehi ◽

Abdulkarim Alanazi

Keyword(s):

Saudi Arabia ◽

Cohort Study ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Atypical Hemolytic Uremic Syndrome ◽

Renal Recovery ◽

Genetic Mutations ◽

Plasma Therapy ◽

High Prevalence ◽

Uremic Syndrome

Introduction: Genetic defects that determine uncontrolled activation of the alternative complement pathway have been well documented, which account for approximately 40–60% of atypical hemolytic uremic syndrome (aHUS) cases worldwide. In Saudi Arabia, nearly half of the marriages are consanguineous, resulting in a high prevalence of such genetic diseases. Recent studies have demonstrated the effectiveness of eculizumab against aHUS. Objective: We report our experience of using plasma therapy or/and eculizumab to treat children with aHUS in a tertiary care center in Saudi Arabia and to compare their clinical characteristics, genetic mutations, and treatment outcomes. Methods: A retrospective cohort study was conducted between January 2010 and May 2017. Data, including demographic parameters, clinical presentation, hospital stay duration, need for dialysis, renal recovery, genetic mutations, and outcomes, were obtained from electronic medical records of all eligible patients. Results: Overall, 21 children with aHUS were included, of which 12 (57.1%) received eculizumab therapy and 9 (42.9%) received only plasma therapy. End-stage renal disease occurred in 7 children (33.3%), of which 4 (57.1%) received only plasma therapy and 3 (42.9%) received eculizumab therapy whose genetic mutations were not related to the complement dysregulation system. No child who received eculizumab therapy showed recurrence; however, 3 children (33.3%) who received plasma therapy alone showed recurrence. Genetic mutations were detected in 12/20 (60%) of those who underwent genetic screening. Conclusions: Children who received eculizumab therapy showed good renal recovery and maintained remission compared with children who received plasma therapy alone. Genetic mutations were detected in 60% of the patients, which was associated with a high prevalence of consanguineous marriages.

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