Looking into a New Challenge, DKA and Covid-19 A Review on Pediatric DKA Cases during New Coronavirus Pandemic Who is to Blame, the Virus or Health System?

2021 ◽  
Vol 5 (7) ◽  
pp. 01-04
Author(s):  
Vida Tajiknia ◽  
Maryam Ghandali ◽  
Ardavan Ahmadvand ◽  
Ali Afrasiabi ◽  
Reza Pirdehghan ◽  
...  

Since the first month of this new pandemic situation, all around the world healthcare system has been facing different challenges and difficulties; patients with chronic diseases such as cancer or diabetes with impaired immune system were at greater risk of infections and complications. It goes without saying that this issue was extremely important among pediatric clinicians dealing with diabetic pediatrics. Diabetes is the number one chronic illness among pediatric patients and the most dangerous and frightened complication of it is Diabetic Ketoacidosis (DKA). Studies have shown a strong association between pandemic and increase in new diabetes type 1 cases and its lethal complication called DKA. Here we are going to take a look at existing data and report about cases with this condition trying to find the missing piece of a big puzzle; what is the role of Covid-19 in causing Diabetes in previously healthy kids and what is the real association between SARS-COV2 virus infection and DKA? We are going to review different studies, possible mechanism, new t1dm cases and old cases, with or without covid infection, DKA cases and its severity.

2008 ◽  
Vol 14 (4) ◽  
pp. 320-323
Author(s):  
Zh. V. Shutskaya

This article summarizes data on homocysteinemia and its influence on vascular pathologic changes in patients with different diseases including diabetes type 1 and type 2. The role of homocystein as an independent risk factor for diabetic nephropathy in children and adolescents is discussed. The problem of homocysteinemia treatment is reviewed.


2014 ◽  
Vol 18 (2 (70)) ◽  
Author(s):  
O. A. Olenovych

According to the results of complex assessment of integral haematological coefficients the development of endogenous intoxication was revealed in case of diabetes mellitus, whose intensity depends on the type of the disease and causes immune system disorganization. The decrease of functional activity of specific immunity as well as nonspecific one in case of diabetes mellitus leads to deregulation of cellular and humoral reactions and depends on diabetes type: in diabetes type 1 the reduction of nonspecific immunoresistance is contributed by microphages, in diabetes type 2 – by macrophages, accompanied by the deficiency of specific immune defense, reliably more significant in diabetes type 2.


2018 ◽  
Vol 80 ◽  
pp. 29-35 ◽  
Author(s):  
Konstantia Kotsani ◽  
Vasiliki Antonopoulou ◽  
Aikaterini Kountouri ◽  
Maria Grammatiki ◽  
Eleni Rapti ◽  
...  

2020 ◽  
Author(s):  
Dominik Sethe ◽  
Arndt Büssing ◽  
Dörte Hilgard ◽  
Bettina Berger

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