Clinical significance of diffusion tensor tractography as a predictor of functional recovery after laminoplasty in patients with cervical compressive myelopathy

2012 ◽  
Vol 17 (2) ◽  
pp. 147-152 ◽  
Author(s):  
Masaya Nakamura ◽  
Kanehiro Fujiyoshi ◽  
Osahiko Tsuji ◽  
Tsunehiko Konomi ◽  
Naobumi Hosogane ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Diffusion Tensor Imaging ◽  
Recovery Rate ◽  
Diffusion Tensor ◽  
Diffusion Tensor Tractography ◽  
Recovery Rates ◽  
Significant Difference ◽  
Cervical Compressive Myelopathy ◽  
Compressive Myelopathy ◽  
And Diffusion

Object This study was conducted to determine whether postoperative changes in the fractional anisotropy (FA) value and diffusion tensor imaging of the cervical spinal cord can predict functional outcome for patients with cervical compressive myelopathy (CCM). Methods Twenty patients with CCM were treated by laminoplasty from 2008 to 2009. Both T2-weighted MRI and diffusion tensor imaging were performed before and after surgery. The FA values were analyzed and fiber tracking was performed. The fiber tract (FT) ratio was calculated according to the following formula: (number of fibers at the compressed level)/(number of fibers at the C-2 level) × 100%. The Japanese Orthopaedic Association scoring system for cervical myelopathy was used to determine pre- and postoperative neurological status of the patients, and the Hirabayashi method was used to calculate the recovery rate. Results There was no significant difference in recovery rates between patients with and those without intramedullary high signal intensity on preoperative T2-weighted images. Substantial differences in FA value among spinal cord, bone, and CSF made it difficult to obtain a precise FA value for the compressed spinal cord. There was a significant correlation between the preoperative FT ratio and the recovery rate (p = 0.0006). A poor outcome (recovery rate < 40%) could be anticipated for CCM patients with preoperative FT ratios below 60%. Conclusions The preoperative FT ratio correlated significantly with the recovery rates in CCM patients. Preoperative diffusion tensor tractography can be a new prognostic predictor for neurological recovery in CCM patients after laminoplasty.

scholarly journals DIFFUSION TENSOR TRACTOGRAPHY

Neurosurgery ◽  
2008 ◽  
Vol 63 (3) ◽  
pp. 452-459 ◽  
Author(s):  
Wai Hoe Ng ◽  
Dennis Lai-Hong Cheong ◽  
Kathleen Joy Khu ◽  
Govidasamy Venkatesh ◽  
Yee Kong Ng ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Magnetic Resonance ◽  
Fractional Anisotropy ◽  
Corticospinal Tract ◽  
Tumor Volume ◽  
Diffusion Tensor ◽  
Diffusion Tensor Tractography ◽  
Significant Difference ◽  
Fiber Number ◽  
And Diffusion

ABSTRACT OBJECTIVE Benign extracerebral lesions such as meningiomas may cause hemiparesis by compression and deviation without infiltrating the white matter. We used magnetic resonance diffusion tensor imaging and diffusion tensor tractography to investigate the effects of benign extracerebral lesions on the corticospinal tract (CST). METHODS Thirteen patients with extracerebral lesions (11 benign meningiomas and 2 benign cysts) underwent magnetic resonance diffusion tensor imaging and diffusion tensor tractography of the CST using fiber assignment by continuous tractography. The CST was reconstructed and assessed by comparing the ipsilateral and unaffected contralateral fibers. The tumor volume, relative fractional anisotropy, fiber deviation, relative fiber number, and relative fiber per voxel were compared between patients without and with temporary presurgical hemiparesis. RESULTS Seven patients without hemiparesis and five patients with temporary hemiparesis were analyzed; one patient had permanent weakness and was excluded from analysis. There was no significant difference in the tumor volume, relative fractional anisotropy, presence of cerebral edema, or CST deviation between groups. In patients with temporary hemiparesis, the median relative fiber number (mean, 0.35 ± 0.32) and relative fiber per voxel (mean, 0.49 ± 0.14) were significantly reduced compared with patients without hemiparesis (0.92 ± 0.55, P = 0.04; and 0.96 ± 0.28, P &lt; 0.01, respectively). CONCLUSION In patients with benign extracerebral lesions, reduction in fiber number and fiber per voxel, but not fiber deviation, correlated with temporary hemiparesis. Clinical recovery was possible even if the CST fibers detected by diffusion tensor tractography were reduced by benign extracerebral lesions.

scholarly journals Application of fiber tractography and diffusion tensor imaging to evaluate spinal cord diseases in dogs

2017 ◽  
Vol 79 (2) ◽  
pp. 418-424 ◽  
Author(s):  
Yuko KONISHI ◽  
Hiroyuki SATOH ◽  
Yasuyoshi KUROIWA ◽  
Mizuki KUSAKA ◽  
Atsushi YAMASHITA ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Fiber Tractography ◽  
Spinal Cord Diseases ◽  
And Diffusion

scholarly journals MR diffusion tensor imaging of the spinal cord: can it help in early detection of cervical spondylotic myelopathy and assessment of its severity?

2019 ◽  
Vol 50 (1) ◽  
Author(s):  
Talaat Ahmed Abd El Hameed Hassan ◽  
Ramy Edward Assad ◽  
Shaimaa Atef Belal
Keyword(s):  
Spinal Cord ◽  
Diffusion Tensor Imaging ◽  
Early Detection ◽  
Cervical Spondylotic Myelopathy ◽  
Diffusion Tensor ◽  
Cervical Spinal Cord ◽  
Cervical Cord ◽  
Mr Diffusion ◽  
Compressive Myelopathy ◽  
Mr Diffusion Tensor Imaging

Abstract Background The aim of this study is to evaluate the potential application of MR diffusion tensor imaging (with calculation of fractional anisotropy (FA) values) in assessment of the spondylotic cervical spinal canal compromise and comparison with the information issued from conventional MR sequences for early detection of cervical spondylotic myelopathy (CSM). Thirty patients (11 males and 19 females) were included in this study; age ranged from 22 to 70 years (mean age = 44). All patients had conventional and diffusion tensor imaging (DTI) examinations of the cervical spine for detection and assessment of degree of cervical cord myelopathy. FA values of the whole cord circumference and at 3, 6, 9, 12 o’clock positions of the normal cord (opposite to C2), opposite to the most affected disc, and below the level of the most affected disc were measured. Results High statistically significant P values were obtained when comparing the FA values of the normal cord with the cord opposite to the most affected disc, the normal cord with the cord below the affected disc and the cord at the level of the most affected disc with the cord below the level of the most affected disc. Conclusions DTI of the cervical spinal cord with FA measurement in patients with cervical spondylosis helps in early detection of cervical cord compressive myelopathy prior to appearance of changes in conventional MRI, which can improve the clinical outcome and help in treatment plans.

Diffusion tensor imaging and fiber tractography in cervical compressive myelopathy: preliminary results

2011 ◽  
Vol 40 (12) ◽  
pp. 1543-1551 ◽  
Author(s):  
Joon Woo Lee ◽  
Jae Hyoung Kim ◽  
Jong Bin Park ◽  
Kun Woo Park ◽  
Jin S. Yeom ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Fiber Tractography ◽  
Preliminary Results ◽  
Cervical Compressive Myelopathy ◽  
Compressive Myelopathy

scholarly journals Reproducibility of tract-specific magnetization transfer and diffusion tensor imaging in the cervical spinal cord at 3 tesla

2009 ◽  
pp. n/a-n/a ◽  
Author(s):  
Seth A. Smith ◽  
Craig K. Jones ◽  
Aliya Gifford ◽  
Visar Belegu ◽  
BettyAnn Chodkowski ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Cervical Spinal Cord ◽  
Magnetization Transfer ◽  
3 Tesla ◽  
Specific Magnetization ◽  
And Diffusion
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