scholarly journals Intracranial hypotension syndrome: a comprehensive review

2003 ◽  
Vol 15 (6) ◽  
pp. 1-8 ◽  
Author(s):  
Michael Paldino ◽  
Alon Y. Mogilner ◽  
Michael S. Tenner

Intracranial hypotension may have variable clinical presentations, but has a rather uniform component of postural headache among its symptomatology. Its symptoms are explainable given the effects of the hypotension and attempts within the craniospinal axis to maintain volume homeostasis in the face of cerebrospinal fluid leakage (Monro–Kellie hypothesis). The imaging corollaries of the consequences of intracranial hypotension are especially well depicted on magnetic resonance imaging studies.

Author(s):  
Kerrie L. Schoffer ◽  
Timothy J. Benstead ◽  
Ian Grant

Background:Spontaneous intracranial hypotension (SIH) is a neurologic syndrome of unknown etiology, characterized by features of low cerebral spinal fluid (CSF) pressure, postural headache and magnetic resonance imaging (MRI) abnormalities.Methods:Four symptomatic cases of SIH presented to our institution over a six-month period. Magnetic resonance imaging studies were performed in all four cases. Diagnostic lumbar puncture was done in all except one case.Results:All of the patients on whom lumbar punctures were performed demonstrated low CSF pressure and CSF protein elevation with negative cultures and cytology. Three out of the four patients exhibited MRI findings of diffuse spinal and intracranial pachymeningeal gadolinium enhancement and extradural or subdural fluid collections. One patient had no MRI abnormalities despite prominent postural headache and reduced CSF pressure at lumbar puncture. All patients recovered with intravenous fluids and conservative treatment.Conclusion:Magnetic resonance imaging abnormalities are found in most, but not all patients, with SIH. Cerebral spinal fluid abnormalities can be detected even in patients with normal MRI studies. It is important to recognize the variability of imaging results in this usually benign disorder.


2005 ◽  
Vol 24 (4) ◽  
pp. 284-290 ◽  
Author(s):  
David F. Abbott ◽  
Helen I. Opdam ◽  
Regula S. Briellmann ◽  
Graeme D. Jackson

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