Cervical intradural extramedullary cavernoma presenting with isolated intramedullary hemorrhage

2008 ◽  
Vol 8 (1) ◽  
pp. 88-91 ◽  
Author(s):  
Juri Kivelev ◽  
Christian N. Ramsey ◽  
Reza Dashti ◽  
Matti Porras ◽  
Olli Tyyninen ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Spinal Cord ◽  
World Literature ◽  
Resonance Imaging ◽  
Unique Case ◽  
True Incidence ◽  
Spinal Cavernoma ◽  
The Central Nervous System ◽  
Intradural Extramedullary ◽  
Spinal Cavernomas

✓Among cavernomas of the central nervous system, spinal ones are rare. The true incidence of spinal cavernomas is unclear, but with widespread use of magnetic resonance imaging the number of cases is increasing. Furthermore, cav-ernomas represent only 5–12% of all vascular anomalies of the spinal cord, with a mere 3% reported to be intradural and intramedullary in location. Cervical spine intradural extramedullary cavernomas are very seldom seen, and only 4 cases have been reported in world literature previously. In this report, a unique case of an intradural extramedullary spinal cavernoma was surgically treated in a patient who presented only with an intramedullary hemorrhage.

scholarly journals Toxicity of Shiga Toxin 1 in the Central Nervous System of Rabbits

2001 ◽  
Vol 69 (10) ◽  
pp. 6545-6548 ◽  
Author(s):  
Jun Fujii ◽  
Yoshimasa Kinoshita ◽  
Takashi Yutsudo ◽  
Hatsumi Taniguchi ◽  
Tom Obrig ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Spinal Cord ◽  
Central Nervous System ◽  
Cerebrospinal Fluid ◽  
Nervous System ◽  
Magnetic Resonance ◽  
Shiga Toxin ◽  
Brain Lesions ◽  
Resonance Imaging ◽  
The Central Nervous System

ABSTRACT The action of Shiga toxin (Stx) on the central nervous system was examined in rabbits. Intravenous Stx1 was 44 times more lethal than Stx2 and acted more rapidly than Stx2. However, Stx1 accumulated more slowly in the cerebrospinal fluid than did Stx2. Magnetic resonance imaging demonstrated a predominance of Stx1-dependent lesions in the spinal cord. Pretreatment of the animals with anti-Stx1 antiserum intravenously completely protected against both development of brain lesions and mortality.

Magnetic resonance imaging findings of a case of an intradural-extramedullary tuberculoma of the spinal cord

2009 ◽  
Vol 69 (2) ◽  
pp. e49-e52 ◽  
Author(s):  
Francesc Calaf ◽  
Laura Oleaga ◽  
Nathalie Sigritz ◽  
Mattia Squarcia ◽  
Sofía González ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Spinal Cord ◽  
Magnetic Resonance ◽  
Imaging Findings ◽  
Resonance Imaging ◽  
Intradural Extramedullary

scholarly journals Multiple myeloma presenting as an intramedullary spinal cord tumor: a case report and review of the literature

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Long Di ◽  
Kevin Huang ◽  
Tigran Kesayan ◽  
Derek Kroll ◽  
Rachid C. Baz ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Spinal Cord ◽  
Central Nervous System ◽  
Multiple Myeloma ◽  
Nervous System ◽  
Magnetic Resonance ◽  
Current Evidence ◽  
Resonance Imaging ◽  
Extramedullary Disease ◽  
The Central Nervous System

Abstract Background Extramedullary disease in multiple myeloma often portends a worse diagnosis. In approximately 1% of cases, multiple myeloma may metastasize to the central nervous system as either leptomeningeal involvement or an intracranial, intraparenchymal lesion. Spinal cord metastases, however, are exceedingly rare. We present a case of spinal cord multiple myeloma as well as a literature review of reported cases. Case presentation A 66-year-old African American man with multiple myeloma presented with acute midthoracic pain and lower extremity paresis and paresthesia. Magnetic resonance imaging of the spine revealed two contrast-enhancing intramedullary enhancing lesions in the T1–T2 and T6–T7 cord. Resection with biopsy yielded a diagnosis of metastatic multiple myeloma. Conclusion To date, only six cases of extramedullary disease to the spinal cord in patients with multiple myeloma have been reported, including our patient’s case. In all cases, neurologic deficit was observed at presentation, and magnetic resonance imaging of the spine revealed an intramedullary, homogeneously enhancing lesion. Current evidence suggests worse prognosis in patients with extramedullary disease to the central nervous system, and treatment paradigms remain debatable.

scholarly journals Brainstem cavernous malformation

2013 ◽  
Vol 32 (01) ◽  
pp. 31-36
Author(s):  
Ariel Roberto Estramiana ◽  
Diana Lara Pinto de Santana ◽  
Eberval Gadelha Figueiredo ◽  
Manoel Jacobsen Teixeira
Keyword(s):  
Magnetic Resonance Imaging ◽  
Spinal Cord ◽  
Central Nervous System ◽  
Clinical Presentation ◽  
Cavernous Malformation ◽  
Vascular Malformations ◽  
Resonance Imaging ◽  
The Central Nervous System ◽  
Magnetic Resonance Imaging Mri ◽  
Brainstem Cavernous Malformation

AbstractCavernous malformation (CM) of the central nervous system (CNS) are acquired or developmental vascular malformations that represent the 5% to 15% of all vascular malformations of the CNS. Eighty to ninety percent of CM are supratentorial, 15% infratentorial, and 5% occur in the spinal cord. The subset of brainstem malformation presents as a very difficult paradigm for treating clinicians. The widespread use of magnetic resonance imaging (MRI) has increased the recognition of this disease. Clinical presentation, pathophysiology and treatment are discussed in this article.

CERVICAL INTRAMEDULLARY GLIOBLASTOMA WITH INTRACRANIAL DISSEMINATION: DESCRIPTION OF A RAPIDLY PROGRESSING CASE AND A LITERATURE REVIEW

2010 ◽  
Vol 13 (01) ◽  
pp. 43-48 ◽  
Author(s):  
Kei Ando ◽  
Yukihiro Matsuyama ◽  
Yoshito Sakai ◽  
Shiro Imagama ◽  
Zenya Ito ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Spinal Cord ◽  
Central Nervous System ◽  
Nervous System ◽  
Magnetic Resonance ◽  
Literature Review ◽  
Resonance Imaging ◽  
Intracranial Lesion ◽  
The Central Nervous System

We present a case of a 65-year-old female with glioblastoma of the spinal cord, which disseminated to an intracranial lesion. Magnetic resonance imaging revealed diffuse swelling at levels C1 to 4, which was pathologically consistent with glioblastoma, and right side pontine parenchyma mass. The patient died after seven weeks of hospitalization. The confirmed diagnosis of glioblastomas was obtained as a result of autopsy. Spinal glioblastomas are rare lesions of the central nervous system with a prognosis as poor as that of their intracranial counterpart. There have been only nine reports in English since 1990, including this case in Japan.

scholarly journals Intradural Spinal Cord Tumors Surgical Experience with Modified Sheehan Technique

2021 ◽  
Vol 5 (7) ◽  
Author(s):  
Ramadan Shamseldein
Keyword(s):  
Magnetic Resonance Imaging ◽  
Spinal Cord ◽  
Magnetic Resonance ◽  
Spinal Injury ◽  
Resonance Imaging ◽  
Spinal Cord Tumors ◽  
Radiological Investigation ◽  
Intramedullary Tumors ◽  
Period Range ◽  
Intradural Extramedullary

Background: Primary spinal cord tumors are rare neoplasms that lead to significant morbidities. They representing about 2–4% of all tumors that affect the central nervous system. According to their relation to the dura, and spinal cord they are classified into extradural, intradural extramedullary and intradural intramedullary tumors. Magnetic resonance imaging is the radiological investigation of choice for the diagnosis of intradural tumors both intra and extramedullary. Surgical excision is the best treatment modality in the majority of patients. Patients and Methods: This is a retrospective study of thirty patients, fifteen males, and fifteen females suffering spinal cord tumors. Median age at diagnosis 41years. Follow up period range from 6months to 43 months with average 24 months. Neurological assessment of the patients carried out by ASIA (American spinal injury association) scoring. Radiological evaluation occurs through MRI (magnetic resonance imaging) with contrast. Of the studied group seven cases were intradural intramedullary and twenty-three cases were intradural extramedullary. The utilized surgical approach was modified Sheehan technique and all the cases were operated by a single surgeon to avoid the inter surgeon variability. Histopathological assessment was done for the excised specimen for all patients. Results: Thoracic region most affected 53.3%, followed by cervical 23.4%, then lumbar (20%) regions. 76.7% intradural extramedullary, and 23.3% intradural intramedullary. Schwannoma 43.3% and Meningioma (20%) were the most pathology. ASIA group C decreased from 40% to 6.7%, and ASIA group D decreased from 60% to 26.7%, and we got a new ASIA group E 66.7% didn’t exist before surgery. Conclusion: The utilized surgical technique is very effective and safe as we get wide corridor for tumor excision, so increasing the effectiveness of operative microscopy and other operative tools, and improve the surgical outcome as noticed in postoperative neurological status.

scholarly journals Multifocal Intradural Extramedullary Anaplastic Ependymoma With Intracranial Involvement at Presentation: A Case Report

2021 ◽  
Vol 7 (3) ◽  
pp. 159-164
Author(s):  
Khashayar Mozaffari ◽  
◽  
Michael A Stellon ◽  
Eric J Chalif ◽  
Michael K Rosner ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Spinal Cord ◽  
Magnetic Resonance ◽  
Malignant Neoplasm ◽  
World Health ◽  
Spinal Tumors ◽  
Resonance Imaging ◽  
Anaplastic Ependymoma ◽  
Intracranial Involvement ◽  
Intradural Extramedullary

Background and Importance: Ependymomas are a rare malignant neoplasm. Multifocal intradural extramedullary anaplastic ependymomas are even more of a rare entity with much of the current knowledge derived from case reports. We presented a case of a multifocal intradural extramedullary anaplastic ependymoma with intracranial involvement at presentation. Case Presentation: A 53-year-old male presented with urinary symptoms. Magnetic resonance imaging revealed two lesions along the spinal cord and two lesions, intracranially. Histopathological examination was consistent with the World Health Organization grade III anaplastic ependymoma. The patient was treated with the gross total resections of spinal cord lesions, followed by radiation therapy to the resection cavities and intracranial lesions. At the 10-month follow-up visit, he reported almost complete resolution of symptoms, and magnetic resonance imaging revealed no recurrence. Conclusion: Despite their rarity, ependymomas should be considered as the differential diagnosis when evaluating spinal tumors. Gross total resection followed by targeted radiotherapy appears to be an effective treatment modality for high-grade lesions.

Spinal Fibrous Hamartoma of Infancy: Case Report

Neurosurgery ◽  
2004 ◽  
Vol 55 (3) ◽  
pp. E728-E731 ◽  
Author(s):  
Shunsuke Yano ◽  
Kazutoshi Hida ◽  
Kazuo Nagashima ◽  
Yoshinobu Iwasaki
Keyword(s):  
Magnetic Resonance Imaging ◽  
Spinal Cord ◽  
Clinical Presentation ◽  
Histopathological Examination ◽  
Fibrous Tissue ◽  
Resonance Imaging ◽  
Partial Removal ◽  
Mesenchymal Tissue ◽  
The Central Nervous System ◽  
Fibrous Hamartoma Of Infancy

Abstract OBJECTIVE AND IMPORTANCE: Fibrous hamartoma of infancy (FHI) in the spinal cord is very rare. It is characterized histopathologically by three elements: fibrous, adipose, and myxoid mesenchymal tissues. CLINICAL PRESENTATION: A 10-month-old boy presented with paraparesis. Magnetic resonance imaging showed a large intradural mass that occupied the space between the T10 and L4 levels. INTERVENTION: We performed partial removal of the mass. Histopathological examination of the lesion revealed that it was composed of collagen bundles and fibrous tissue interspersed with adipose tissue, mesenchymal tissue, and glial tissue, and it was diagnosed as FHI. CONCLUSION: FHI in the central nervous system, especially in the spine, is very rare, and the presence of glial tissue admixed with particular components of FHI is quite exceptional.

scholarly journals Intradural Extramedullary Metastasis of the Upper Thoracic Spine – Case Report and Literature Review

Folia Medica ◽  
2019 ◽  
Vol 61 (4) ◽  
pp. 624-629
Author(s):  
Ivo Kehayov ◽  
Sylvia Genova ◽  
Maria Gicheva ◽  
Bahar Nuri ◽  
Borislav Kitov
Keyword(s):  
Quality Of Life ◽  
Magnetic Resonance Imaging ◽  
Spinal Cord ◽  
Surgical Decompression ◽  
Cement Augmentation ◽  
Resonance Imaging ◽  
Upper Thoracic Spine ◽  
Intradural Extramedullary ◽  
Upper Thoracic

We report a case of 46-year-old male operated on for moderately differentiated lung adenocarcinoma. Postoperatively, he underwent six courses of chemotherapy and radiotherapy. He developed progressive severe inferior paraparesis accompanied by excruciating pain between the shoulders two years later. Magnetic resonance imaging revealed metastases in the bodies of T2 and T3 vertebrae with adjacent intradural extramedullary lesion compressing the spinal cord. The patient underwent surgical decompression and vertebral body cement augmentation that lead to pain relief and partial neurological recovery. The histological examination was consistent with metastases from low differentiated pulmonary adenocarcinoma. Surgical resection of intradural extramedullary metastasis improves patient quality of life by reducing pain intensity and neurological deficit.

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