scholarly journals CHEMICAL PROFILE AND BIOLOGICAL ACTIVITY OF ESSENTIAL OILS FROM Psidium guajava GROWN IN TIMOR ISLAND-EASTERN INDONESIA

2021 ◽  
Vol 14 (02) ◽  
pp. 1312-1315
Author(s):  
Antonius R. B. Ola ◽  
Yosefa Cysilia Bheku Dje ◽  
Agustina E Nahas ◽  
Petronela Nenotek ◽  
Theo Da Cunha ◽  
...  
2021 ◽  
Vol 10 (9) ◽  
pp. e6110917710
Author(s):  
Loren Cristina Vasconcelos ◽  
Esdras de Souza Santos ◽  
Luiza Alves Mendes ◽  
Marcia Flores da Silva Ferreira ◽  
Milene Miranda Praça-Fontes

Natural products with biological activity, such as essential oils, can be used in the search for and development of ecological herbicides as an alternative to reduce the damage caused by synthetic herbicides. This work to aimed to determine the chemical composition and phytotoxic properties of the essential oils, at concentrations of 3000, 1500, 750, 375 and 187.5 µg/mL, of four cultivars of Psidium guajava (guava) evaluated on germination and root growth of plant models Lactuca sativa and Sorghum bicolor, as well as in the L. sativa cell cycle.  Exposure to essential oils reduced germination and root growth in bioassays, especially at the highest concentration (3000 µg/mL). The essential oils interfered in the normal dynamics of the cell cycle of L. sativa at most concentrations, causing a decrease in the mitotic index and increasing of chromosomal alterations, evidencing aneugenic and clastogenic action. The biological activity of the oils was associated with the presence of sesquiterpenes and monoterpenes found here, such as caryophyllene oxide, (E) -caryophyllene, and limonene. Thus, the essential oils of cultivars of guava demonstrated the promising potential for use as natural herbicides.


2021 ◽  
Vol 16 (2) ◽  
pp. 1934578X2199615
Author(s):  
Lucas Botelho Jerônimo ◽  
Jamile S. da Costa ◽  
Laine C. Pinto ◽  
Raquel C. Montenegro ◽  
William N. Setzer ◽  
...  

This work analyzed the chemical compositions and evaluated the antioxidant and cytotoxic activities of essential oils (EO) of Eugenia patrisii (Epat), Eugenia stipitata (Esti), Myrcia splendens (Mspl), Myrcia sylvatica (Msyl), Psidium guajava (Pgua), and Psidium guineense (Pgui-1 and Pgui-2) from the Brazilian Amazon. Sesquiterpenoids were found in high concentrations in the oils of E. patrisii and M. splendens, which were rich in E-caryophyllene (32.0% and 45.8%); E. stipitata and M. sylvatica, which displayed germacrene D (11.8%) and germacrene B (24.5%); and P. guajava that showed epi-β-bisabolol (16.1%) as the main compound. However, P. guineense samples (Pgui-1 and Pgui-2) were rich in monoterpenoids such as limonene (Pgui-1: 30.2%; Pgui-2 30.4%) and α-pinene (Pgui-1: 22.5%; Pgui-2: 17.7%). The samples showed a weak and moderate antioxidant activities in the DPPH assay, displaying inhibition rates from 11.5% to 38.6% (at 10 mg/mL). All samples were cytotoxic against human cancer cells by the MTT method. Epat oil showed higher activity against melanoma (SKMEL-19, IC505.8 µg/mL), gastric (AGP01, IC503.2 µg/mL), and colon (HCT116, IC506.7 µg/mL). Meanwhile, the samples Pgua and Pgui were more active against breast cancer cells (MCF7, IC5012.4 µg/mL and 11.6 µg/mL, respectively).


2019 ◽  
Vol 31 (4) ◽  
pp. 993-998 ◽  
Author(s):  
Afaf Weli ◽  
Amna Al-Kaabi ◽  
Jamal Al-Sabahi ◽  
Sadri Said ◽  
Mohammad Amzad Hossain ◽  
...  

2016 ◽  
Vol 13 (5) ◽  
pp. 571-581 ◽  
Author(s):  
Monica Rosa Loizzo ◽  
Rosa Tundis ◽  
Marco Bonesi ◽  
Giuseppe Di Sanzo ◽  
Alessandra Verardi ◽  
...  

2004 ◽  
Vol 16 (5) ◽  
pp. 504-506 ◽  
Author(s):  
Francisco J.B. dos Santos ◽  
J. Arimatéia D. Lopes ◽  
A. M. Graças L. Cito ◽  
Evaldo H. de Oliveira ◽  
Sidney G. de Lima ◽  
...  

2016 ◽  
Vol 76 (2) ◽  
pp. 195-200 ◽  
Author(s):  
Fatiha Medjahed ◽  
Abdelaziz Merouane ◽  
Abdelkader Saadi ◽  
Ammar Bader ◽  
Pier Luigi Cioni ◽  
...  

2016 ◽  
Vol 28 (6) ◽  
pp. 557-564 ◽  
Author(s):  
Bhaskaruni R. Rajeswara Rao ◽  
Ganjigunta Adinarayana ◽  
Arigari Niranjan Kumar ◽  
Dharmendra K. Rajput ◽  
Kodakandla V. Syamasundar

Molecules ◽  
2020 ◽  
Vol 25 (11) ◽  
pp. 2612 ◽  
Author(s):  
Giuseppe Mannino ◽  
Carla Gentile ◽  
Alessandra Porcu ◽  
Chiara Agliassa ◽  
Fabio Caradonna ◽  
...  

Annona cherimola (Cherimoya) and Annona atemoya (Atemoya) are tropical plants known for their edible fruit. Scientific data suggest that their leaves, used in traditional medicine in the form of teas or infusions without evidence of toxicity, contain several bioactive compounds. However, only Annona muricata among all the Annona species is currently used in the nutraceutical field, and its dried leaves are marketed for tea preparation. In this work, we explored the nutraceutical potential of Atemoya and Cherimoya leaves, by evaluating their chemical profile and functional properties. Phytochemical analyses showed large amounts of phenolic compounds, in particular proanthocyanidins, and identified 18 compounds, either flavonoids or alkaloids. Concerning biological activity, we found antioxidative properties correlated with polyphenols, and antiproliferative activity against HeLa and HepG2 cell lines correlated with alkaloids. The obtained results demonstrate the potential use of Annona cherimola leaves for the preparation of dietary supplements aimed to promote the physiological redox balance. Moreover, the varietal comparison suggests that two commercial cultivars (Campas and White) and the local Torre 1, better suit this purpose. On the other hand, among the studied cultivars, Campas and Torre 1 are also the richest in alkaloids and, in consideration of the anti-proliferative properties of their extracts, dietary supplements based on these cultivars might also have chemo-preventive effects.


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