Relative Gastro-Intestinal Stability of Carotene and Vitamin A and Protective Effect of Xanthophyll.

1947 ◽  
Vol 65 (2) ◽  
pp. 207-210 ◽  
Author(s):  
W. C. Sherman
2019 ◽  
Vol 24 (8) ◽  
pp. 3037-3046
Author(s):  
Luciano Lima Correia ◽  
Hermano Alexandre Lima Rocha ◽  
Jocileide Sales Campos ◽  
Anamaria Cavalcante e Silva ◽  
Dirlene Mafalda Ildefonso da Silveira ◽  
...  

Abstract 200 million pre-school age children are not developing properly. Delays in child development are associated with multiple factors. This study aims to analyze if vitamin A supplementation is associated with improved development and how this effect could be mediated by nutritional status. Population-based study surveyed a representative sample of 8000 households, 1232 children 0-35 months, in the state of Ceará, Brazil. The variables analysed included child developmental status, nutritional determinants and confounding factors. The main effects and interactions were evaluated using Cox regressive models. Vitamin A supplementation showed protective effect to delay in cognitive and motor development modified by interaction with nutritional status. While well-nourished supplemented children presented a 67% lower risk of cognitive delay (adjusted PRR = 0·33 [0·21–0·53]), stunted children had no benefit from supplementation (adjusted PRR = 0·97 [0·39–2·40]). Vitamin A supplementation has a protective effect on child development, but not in stunted children. This suggests that supplementation is effective in promoting child development, especially if associated to a joint effort to improve the nutritional status of children, given the importance of this mediator.


2013 ◽  
Vol 32 (6) ◽  
pp. 1012-1016 ◽  
Author(s):  
Sinead Field ◽  
Faye Elliott ◽  
Juliette Randerson-Moor ◽  
Kairen Kukalizch ◽  
Jennifer H. Barrett ◽  
...  

2016 ◽  
Vol 130 (5) ◽  
pp. 440-446 ◽  
Author(s):  
I Aladag ◽  
M Guven ◽  
M Songu

AbstractObjective:To investigate the use of systemic N-acetylcysteine and vitamin A in the prevention of gentamicin ototoxicity in rats.Methods:Forty-two Wistar rats were divided into four groups according to treatment: intratympanic saline, intratympanic gentamicin, intraperitoneal vitamin A after intratympanic gentamicin, and intraperitoneal N-acetylcysteine after intratympanic gentamicin. Signal-to-noise ratio and distortion product otoacoustic emissions were evaluated in all groups.Results:N-acetylcysteine had a significant protective effect at 1.5, 2, 3, 4, 6 and 8 kHz, whilst vitamin A had a significant protective effect at 2, 3, 4 and 6 kHz, as determined by the distortion product otoacoustic emission measurements. According to the signal-to-noise measurements, N-acetylcysteine had a significant protective effect at 1.5, 2, 3, 4, 6 and 8 kHz, whilst vitamin A had a significant protective effect at 3, 6 and 8 kHz.Conclusion:Gentamicin-induced hearing loss in rats may be prevented by the concomitant use of vitamin A and N-acetylcysteine. Specifically, N-acetylcysteine appeared to have a more protective effect than vitamin A for a greater range of noise frequencies.


2020 ◽  
Vol 8 (1.1) ◽  
pp. 7256-7270
Author(s):  
Eman Mohamed Kamel ◽  
◽  
Shimaa Anter Fareed ◽  
Nassar Ayoub ◽  
◽  
...  

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