Difficulties of differential diagnosis of primary hyperaldostronism and arterial hypertension by the example of a clinical observation

2019 ◽  
Vol 17 (4) ◽  
pp. 179-181
Author(s):  
Z. A. Afanasieva ◽  
◽  
D.P. Nikulina ◽  
T. L. Sharapov ◽  
N. I. Bariev ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Arterial Hypertension ◽  
Clinical Observation

scholarly journals Pulmonary arterial hypertension associated with systemic scleroderma

2021 ◽  
Vol 99 (1) ◽  
pp. 68-74
Author(s):  
E. K. Popova ◽  
N. S. Arkhipova ◽  
N. V. Ilyin ◽  
A. D. Asekritov ◽  
E. A. Ignatiev ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Pulmonary Arterial Hypertension ◽  
Early Diagnosis ◽  
Arterial Hypertension ◽  
Pulmonary Vascular Resistance ◽  
Clinical Observation ◽  
Systemic Scleroderma ◽  
Late Initiation ◽  
Pulmonary Arterial ◽  
The Republic

Pulmonary arterial hypertension (PAH) is an orphan disease characterized by an increase in pulmonary vascular resistance (PVR). PAH is a pathology, difficult to diagnose due to the non-specificity of its first strokes. The prognosis of PAH is extremely unfavorable without early diagnosis and treatment, as with systemic scleroderma, 60% of patients die in the first 2 years. In the Republic of Sakha (Yakutia), there are currently 38 patients with PAH, and a tendency towards an increase in their number is noted. The necessity to conduct scientific research on PAH patients living in the Republic of Sakha (Yakutia) is urgent due to the fact. The article represents a 1.5-year clinical observation of a 45-year-old patient with PAH associated with systemic scleroderma, which demonstrates difficulties in the differential diagnosis of PAH, late initiation of PAH-specific pharmacotherapy. The article discusses the efficiency of the original PAH-specific drugs use, and their generics.

ELECTROENCEPHALOGRAPHIC FINDINGS IN BREATH HOLDING SPELLS

PEDIATRICS ◽  
1955 ◽  
Vol 15 (5) ◽  
pp. 595-599
Author(s):  
Niels L. Low ◽  
Erna L. Gibbs ◽  
Frederic A. Gibbs
Keyword(s):  
Differential Diagnosis ◽  
Clinical Diagnosis ◽  
Slow Wave ◽  
Clinical Observation ◽  
Seizure Activity ◽  
Breath Holding ◽  
Convulsive Disorders

After reviewing the literature on breath holding spells, it seemed desirable to determine whether any electroencephalographic abnormality is revealed by recordings during sleep in such cases. One hundred twenty-nine children between the ages of 7 months and 11½ years with breath holding spells were examined electroencephalographically while awake and during sleep. Seventy-seven of these children were boys and 52 were girls. All these children but one had normal electroencephalograms. One tracing taken during a breath holding spell is reproduced which shows slow wave but no seizure activity. The clinical diagnosis is discussed and it is concluded that the electroencephalogram in combination with the history and clinical observation is of value in the differential diagnosis between breath holding spells and convulsive disorders.

scholarly journals Coprostasia and pregnancy (clinical observation)

2015 ◽  
Vol 64 (4) ◽  
pp. 57-61
Author(s):  
Evgeniy Sergeevich Mikhaylin ◽  
Lada Anatol’evna Ivanova ◽  
Aleksey Gennad’evich Savitskiy ◽  
Anna Gennad’evna Minina ◽  
Larisa Pavlovna Zhibura ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Clinical Observation ◽  
Discharge Home

The article presents the case of the formation of a giant fecal stone in 34 weeks of pregnancy, which demanded the differential diagnosis of tumors originating from the pelvis. The patient was conducted multistage finger fragmentation of the fecal stone, alternating with the enema. The patient was discharge home with progressing pregnancy.

scholarly journals Change of differential diagnosis tactics in the process of clinical observation ofa patient

2008 ◽  
Vol 7 (2) ◽  
pp. 79-83
Author(s):  
O. V. Kalinina
Keyword(s):  
Lung Cancer ◽  
Differential Diagnosis ◽  
Clinical Observation ◽  
Clinical Symptoms

The complicated ratios of clinical symptoms of internal lesions during central lung cancer are demonstrated in the article when changes of differential diagnosis tactics were required for diagnosing that necessary keeping is priority of the clinical appraisal of the results inspection patient.

scholarly journals Macroglossia reveals multiple myeloma

2021 ◽  
Vol 7 (3) ◽  
Author(s):  
Maria Bonvicini ◽  
Davide Crapanzano ◽  
Susanna Fenu ◽  
Marco Giordano ◽  
Lorenzo Palleschi
Keyword(s):  
Multiple Myeloma ◽  
Bone Marrow ◽  
Differential Diagnosis ◽  
Arterial Hypertension ◽  
Supportive Care ◽  
Loss Of Weight ◽  
Bright Orange ◽  
History Of ◽  
Congo Red Staining ◽  
One Year

We present an eighty-year old man with a one year history of progressive macroglossia, dysphagia and loss of weight. He had a medical history of arterial hypertension and prostatic hypertrophy which he had under good therapeutic control. The entire tongue was swollen, had hard solidity and was slightly painful upon palpation. A tongue biopsy revealed an amyloid deposition as it coloured bright orange-red on Congo Red staining and lead us subsequently to the diagnosis of amyloidosis; then a bone marrow biopsy confirmed the diagnosis of multiple myeloma. The case was further evaluated by a multidisciplinary team who considered it appropriate to start a lowdose melphalan treatment combined with supportive care. When macroglossia in the tongue is confirmed to be amyloidosis the differential diagnosis should include systemic amyloidosis deposition and multiple myeloma.

scholarly journals A Patient with Uncontrollable Belching: What to Do?

2019 ◽  
Vol 28 (6) ◽  
pp. 68-76 ◽  
Author(s):  
I. V. Maev ◽  
Yu. A. Kucheryaviy ◽  
E. V. Barkalova ◽  
M. A. Ovsepyan
Keyword(s):  
Differential Diagnosis ◽  
High Resolution ◽  
Esophageal Manometry ◽  
Speech Therapy ◽  
Clinical Observation ◽  
Behavioural Disorders ◽  
Speech Therapist ◽  
Esophageal Sphincter ◽  
The Moment ◽  
Transient Relaxation

Aim.In this paper, we discuss the clinical significance of belching and present a clinical case with the description of the belching differential diagnosis.Main findings.Belching may be either a physiological or a pathological phenomenon. Pathological belching requires an adequate diagnostic approach in order to clarify the nature of its occurrence. Gastric belching occurs reflexively at the moment of stomach stretching by excess air trapped during swallowing, which initiates the transient relaxation of the lower esophageal sphincter. As a consequence, the swallowed air escapes from the stomach first into the esophagus and then into the throat. Supragastric belching is a phenomenon, in which the air entering the esophagus does not reach the stomach, but rapidly returns to the throat. In this case, unlike aerophagia, the air entering the esophagus is not accompanied by the act of swallowing. Supragastric belching is not a reflex process; rather, it is considered to be a manifestation of behavioural disorders. 24-hour pH-impedancemetry and high-resolution esophageal manometry are highly informative methods for detecting various types of belching (gastric and supragastric), as well as their mechanisms. We present a clinical observation of a 47-year-old patient suffering from supragastric belching and treated by speech therapy under the supervision of a speech therapist.Conclusion.24-hour pH-impedancemetry and high-resolution esophageal manometry (also in combination with impedancemetry) provide a complete differential diagnosis of belching and allow the most effective patient management strategy to be selected.

scholarly journals Central Giant Cell Granuloma of the Mandible: Clinical Observation

2021 ◽  
Vol 8 ◽  
Author(s):  
Asma Azzouzi ◽  
Karima El Harti
Keyword(s):  
Differential Diagnosis ◽  
Giant Cell ◽  
Histological Examination ◽  
Clinical Observation ◽  
Central Cell ◽  
Giant Cell Granuloma ◽  
Central Giant Cell Granuloma ◽  
Plastic Type ◽  
Wide Range ◽  
Small Bones

The Giant central cell granuloma (GCCG) is a benign intra-osseous lesion of the neo-plastic type. It appears mainly in the mandible, but can be observed in the maxilla and small bones of the hand and foot, with a predilection for the female sex and prevalence at a young age. Its diagnosis is clinical and radiological, confirmed by histological examination. The differential diagnosis is biological because it has a wide range of morphologies and a misinterpretation with other giant cell lesions can often occur. The authors present a case of the Giant central cell granuloma in a 62-year-old woman developing for 3 years after dental extractions. The most favorable treatment for giant cell granulomas is surgical whose main objective is to prevent recurrences.

scholarly journals DIFFERENTIAL DIAGNOSIS OF ROSACEA AND SKIN TUBERCULOSIS AS AN EXAMPLE OF A CLINICAL CASE

2014 ◽  
Vol 13 (5) ◽  
pp. 203-208
Author(s):  
M. L. Aripova ◽  
S. A. Khardikova
Keyword(s):  
Differential Diagnosis ◽  
Clinical Diagnosis ◽  
Clinical Case ◽  
Clinical Observation ◽  
Skin Tuberculosis

In this paper for a clinical observation of a patient with rosacea, and patients with a flat form of lupus tuberculosis presented a differential clinical diagnosis of tuberculosis of the skin.

scholarly journals The importance of functional diagnostics in determining the cause of antisecretary therapy inefficiency in a patient with heartburn: clinical observation

2021 ◽  
pp. 46-53
Author(s):  
E. V. Barkalova ◽  
D. N. Andreev ◽  
M. A. Ovsepian
Keyword(s):  
Differential Diagnosis ◽  
High Resolution ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Research Methods ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Reflux Disease ◽  
Esophageal Manometry ◽  
Clinical Observation

One of the main symptoms of gastroesophageal reflux disease is heartburn, for the relief of which proton pump inhibitors are traditionally prescribed. However, there are frequent cases of heartburn, refractory to antisecretory therapy, when there is no complete relief of the symptom or only a partial clinical effect. The reason for an unsatisfactory response may be the functional genesis of heartburn. The purpose of the presented clinical observation is to demonstrate the heterogeneity of patients with heartburn, the role of functional research methods in the differential diagnosis of various conditions that accompany this symptom. A 42-year-old patient was admitted for an additional clinical examination with complaints of heartburn refractory to antisecretory therapy, which included high-resolution esophageal manometry, 24-hours pH-impedance. The manometric assessment of the structure and function of the lower esophageal sphincter, as well as the contractility of the thoracic esophagus, revealed no violations. The data of 24-hours pH-impedance demonstrated the absence of pathological reflux and the association of active symptoms with refluxes, which determined the functional nature of heartburn and explained the ineffectiveness of treatment with proton pump inhibitors. Heartburn can be functional in  nature and significantly reduce the  quality of  life of  patients. Functional heartburn requires different management tactics from gastroesophageal reflux disease, which is based on an adequate differential diagnosis, including functional research methods such as high-resolution esophageal manometry and 24-hours pH-impedance measurement, which allow to exclude other conditions accompanied by similar symptoms. 

scholarly journals Hemorrhagic testicular infarction as a complication of COVID-19 (SARS-CoV-2)

2021 ◽  
Vol 14 (2) ◽  
pp. 70-72
Author(s):  
T.I. Derevyanko ◽  
◽  
S.V. Pridchin ◽  
◽  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Arterial Hypertension ◽  
Blood Clotting ◽  
Clinical Observation ◽  
City Hospital ◽  
Hemorrhagic Infarction ◽  
Testicular Infarction

Introduction. Statistically, adult patients with testicular infarction make up 7-10% of the population of all acute urological pathology. This is one of the urological nosologies, which is а part of a group of diseases called  acute scrotum . Ischemic heart attack occurs as a result of an acute violation of the blood supply to the testicle from the testicular artery. Hemorrhagic infarction usually occurs as a result of impaired microcirculation or embolization of the arteries and arterioles of the testicle and is most often segmental in nature. Conditions associated with increased blood clotting also create conditions for vein obstruction with subsequent tissue necrosis in any organ, including in the testicles. It is known that COVID-19 (SARS-COV-2) causes a pathological increase in blood clotting in the patient's body and it's most dangerous complication is thrombosis in various blood vessels of the patient's organs, which often causes acute ischemia of these organs and even death in patients with COVID 19. Materials and methods. The authors consider 3 similar clinical observations of hemorrhagic testicular infarction in patients suffering from COVID-19 (SARS-COV-2) and who were in the specialized COVID department of the city hospital of Pyatigorsk (Russia, Stavropol Territory). All 3 patients were aged from 67 to 88 years and had a concomitant pathology from the cardiovascular system in the form of arterial hypertension, as well as type 2 diabetes mellitus. The authors provide one case in detail, since all 3 cases followed the same clinical scenario. Clinical observation: Patient B. 66 years old, who was in a specialized COVID department with a diagnosis of: Coronovirus infection caused by COVID 19 (confirmed), moderate form of UO7. 1, community-acquired bilateral lobar pneumonia, acute respiratory distress syndrome, respiratory failure. Concomitant diseases: atherosclerotic cardiosclerosis, arterial hypertension, type 2 diabetes mellitus. The patient received therapy for the underlying disease, but on the 9th day of his stay in the hospital, he had an acute hemorrhagic infarction of the left testicle. The diagnosis was confirmed by laboratory and instrumental examination. An emergency left-sided orchectomy was performed, and the diagnosis was confirmed histologically. Similar clinical situations were observed in two other patients with the same outcome. Conclusions. Hemorrhagic testicular infarction in patients with COVID-19 in our clinical observation can be considered as a complication of COVID-19, or as its clinical manifestation in the organs of the male reproductive system.

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