scholarly journals Serologic Screening of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Cats and Dogs during First Coronavirus Disease Wave, the Netherlands

2021 ◽  
Vol 27 (5) ◽  
Author(s):  
Shan Zhao ◽  
Nancy Schuurman ◽  
Wentao Li ◽  
Chunyan Wang ◽  
Lidwien A.M. Smit ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
The Netherlands ◽  
Serologic Screening

scholarly journals Low awareness of past SARS-CoV-2 infection in healthy adults

2020 ◽  
Author(s):  
Katja van den Hurk ◽  
Eva-Maria Merz ◽  
Femmeke J. Prinsze ◽  
Marloes L.C. Spekman ◽  
Franke A. Quee ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
The Netherlands ◽  
Healthy Adults ◽  
Economic Consequences ◽  
Control Measures ◽  
Questionnaire Data ◽  
Online Questionnaire ◽  
Past Infection ◽  
Virus Control ◽  
Age And Sex

Background The coronavirus disease 2019 (COVID-19) pandemic challenges governments worldwide to balance appropriate virus control measures and their societal and economic consequences. These control measures include the identification, isolation and testing of potentially infected individuals. As this relies on an individual's awareness of infection, we investigated the extent to which healthy adults suspected having had COVID-19, and how COVID-19 suspicion and symptoms relate to antibodies indicative of a past infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Methods and findings Individuals donating plasma anywhere in the Netherlands between May 11th and 18th were screened for total SARS-CoV-2 antibodies using ELISA and invited to participate in an online questionnaire about COVID-19-related symptoms and awareness. Antibody and questionnaire data were complete for 3,676 individuals, including 239 (6.5%) that tested positive for SARS-CoV-2 antibodies. Here, we show that a 38% of the individuals that tested positive for SARS-CoV-2 antibodies reported having had no or only very mild symptoms at any time during the peak of the epidemic. The loss of taste and/or smell in particular was significantly associated with seropositivity, independent of age and sex. Forty-eight percent of antibody-positive persons did not suspect having had COVID-19, in spite of most of them reporting symptoms. Conclusions Awareness of infection was low among individuals that tested positive for SARS-CoV-2 antibodies, even at the peak of the epidemic. Improved awareness and recognition of COVID-19 symptoms and tracing of asymptomatic contacts is crucial to halting SARS-CoV-2 transmission.

scholarly journals Genome Sequence of a Minacovirus Strain from a Farmed Mink in The Netherlands

2021 ◽  
Vol 10 (8) ◽  
Author(s):  
Kirsty T. T. Kwok ◽  
Myrna M. T. de Rooij ◽  
Felisita F. Sinartio ◽  
Lidwien A. M. Smit ◽  
Marion P. G. Koopmans ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
The Netherlands ◽  
Real Time ◽  
Genome Sequence ◽  
Deep Sequencing ◽  
Real Time Pcr ◽  
Fecal Sample ◽  
Viral Genome ◽  
Rt Pcr ◽  
Content Type

ABSTRACT We report the genome sequence of a Minacovirus strain identified from a fecal sample from a farmed mink (Neovison vison) in The Netherlands that was tested negative for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using real-time PCR (RT-PCR). The viral genome sequence was obtained using agnostic deep sequencing.

scholarly journals High SARS-CoV-2 attack rates following exposure during singing events in the Netherlands, September-October 2020

2021 ◽  
Author(s):  
Anita A. Shah ◽  
Florien Dusseldorp ◽  
Irene K. Veldhuijzen ◽  
Margreet J.M. te Wierik ◽  
Alvin Bartels ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
The Netherlands ◽  
Index Case ◽  
Sequencing Data ◽  
Airborne Transmission ◽  
Indirect Contact ◽  
Increased Risk ◽  
Respiratory Droplets ◽  
Droplet Transmission ◽  
Interpretation Of Results

AbstractPrevious reports indicate that there may be an increased risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission during singing events. We describe SARS-CoV-2 transmission in six singing events from September–October 2020, across the Netherlands, with attack rates from 25–74%. We investigated potential routes of SARS-CoV-2 transmission for each event. Events included 9–21 persons, aged 20–79 years. SARS-CoV-2 transmission likely took place during five out of six events; a possible index case could be identified in four out of five clusters. Limited sequencing data was available, hampering interpretation of results. Indirect contact and droplet transmission (<1.5m) may have caused some cases, but are unlikely to explain the high attack rates. The previously published AirCoV2 model indicated that airborne transmission (via infectious droplets/ aerosols over longer distances (>1.5m)) due to singing is possible in case of supershedder presence (≥1010 RNA copies/mL). Also, airflow expelling respiratory droplets over longer distances (>1.5m) may have influenced transmission. In conclusion, a combination of transmission routes probably caused these five clusters. Proportions attributable to each route cannot be deduced. It is possible that airborne transmission of SARS-CoV-2 due to singing (partly) led to the high attack rates observed in these clusters.

scholarly journals Increased risk of infection with SARS-CoV-2 Beta, Gamma, and Delta variant compared to Alpha variant in vaccinated individuals

2021 ◽  
Author(s):  
Stijn P. Andeweg ◽  
Harry Vennema ◽  
Irene Veldhuijzen ◽  
Naomi Smorenburg ◽  
Dennis Schmitz ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
The Netherlands ◽  
Immune Status ◽  
Risk Of Infection ◽  
National Community ◽  
Increased Risk ◽  
Alpha Variant ◽  
Induced Immunity

The extent to which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOC) break through infection- or vaccine-induced immunity is not well understood. Here, we analyze 28,578 sequenced SARS-CoV-2 samples from individuals with known immune status obtained through national community testing in the Netherlands from March to August 2021. We find evidence for an increased risk of infection by the Beta (B.1.351), Gamma (P.1), or Delta (B.1.617.2) variants compared to the Alpha (B.1.1.7) variant after vaccination. No clear differences were found between vaccines. However, the effect was larger in the first 14-59 days after complete vaccination compared to 60 days and longer. In contrast to vaccine-induced immunity, no increased risk for reinfection with Beta, Gamma or Delta variants relative to Alpha variant was found in individuals with infection-induced immunity.

scholarly journals Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands, March 2020

2020 ◽  
Vol 25 (16) ◽  
Author(s):  
Alma Tostmann ◽  
John Bradley ◽  
Teun Bousema ◽  
Wing-Kee Yiek ◽  
Minke Holwerda ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
The Netherlands ◽  
Predictive Value ◽  
Healthcare Workers ◽  
General Malaise ◽  
Ocular Pain ◽  
Screening Strategies ◽  
Targeted Screening ◽  
Discriminative Value ◽  
Muscle Ache

Healthcare workers (n = 803) with mild symptoms were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (n = 90 positive) and asked to complete a symptom questionnaire. Anosmia, muscle ache, ocular pain, general malaise, headache, extreme tiredness and fever were associated with positivity. A predictive model based on these symptoms showed moderate discriminative value (sensitivity: 91.2%; specificity: 55.6%). While our models would not justify presumptive SARS-CoV-2 diagnosis without molecular confirmation, it can contribute to targeted screening strategies.

scholarly journals Excess Deaths during Influenza and Coronavirus Disease and Infection-Fatality Rate for Severe Acute Respiratory Syndrome Coronavirus 2, the Netherlands

2021 ◽  
Vol 27 (2) ◽  
Author(s):  
Liselotte van Asten ◽  
Carel N. Harmsen ◽  
Lenny Stoeldraijer ◽  
Don Klinkenberg ◽  
Anne C. Teirlinck ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
The Netherlands ◽  
Fatality Rate ◽  
Excess Deaths

scholarly journals Testing wastewater to detect severe acute respiratory syndrome coronavirus 2 in communities

2020 ◽  
Vol 114 (10) ◽  
pp. 782-783 ◽  
Author(s):  
Anthony D Harries ◽  
Selma dar Berger ◽  
Srinath Satyanarayana ◽  
Pruthu Thekkur ◽  
Ajay M V Kumar
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
The Netherlands ◽  
Research Groups ◽  
The World ◽  
Low Levels ◽  
Wastewater Samples

Abstract Research groups around the world are starting to analyse whether wastewater surveillance is a useful tool to monitor the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in communities. Reported studies from the Netherlands, USA, Australia and France have demonstrated that SARS-CoV-2 can be detected and quantified in wastewater, allowing the total number of community infections to be estimated as well as monitoring whether the virus has returned to a community after elimination. Further work is required to improve the quantification of virus, to better detect the virus at low levels and to ensure wastewater samples are representative of the community under surveillance.

No Value for Routine Serologic Screening for B orrelia burgdorferi in Patients With Uveitis in the Netherlands

2016 ◽  
Vol 166 ◽  
pp. 189-193 ◽  
Author(s):  
Hawkar Kazi ◽  
Jolanda D.F. de Groot-Mijnes ◽  
Ninette H. ten Dam-van Loon ◽  
Jeannette Ossewaarde-van Norel ◽  
Jan Jelrik Oosterheert ◽  
...  
Keyword(s):  
The Netherlands ◽  
No Value ◽  
Serologic Screening

scholarly journals Rapid assessment of regional SARS-CoV-2 community transmission through a convenience sample of healthcare workers, the Netherlands, March 2020

2020 ◽  
Vol 25 (12) ◽  
Author(s):  
Chantal B Reusken ◽  
Anton Buiting ◽  
Chantal Bleeker-Rovers ◽  
Bram Diederen ◽  
Mariëtte Hooiveld ◽  
...  
Keyword(s):  
Risk Management ◽  
Severe Acute Respiratory Syndrome ◽  
The Netherlands ◽  
Healthcare Workers ◽  
Rapid Assessment ◽  
Convenience Sample ◽  
Community Transmission ◽  
Respiratory Complaints ◽  
Epidemiological Link

To rapidly assess possible community transmission in Noord-Brabant, the Netherlands, healthcare workers (HCW) with mild respiratory complaints and without epidemiological link (contact with confirmed case or visited areas with active circulation) were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Within 2 days, 1,097 HCW in nine hospitals were tested; 45 (4.1%) were positive. Of six hospitals with positive HCW, two accounted for 38 positive HCW. The results informed local and national risk management.

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