scholarly journals INTRAPERITONEAL USING OF BUPIVАCAIN FOR THE ANESTHESIA OF PATIENTS AFTER LAPAROSCOPIC CHOLECYSTECTOMY

2018 ◽  
Vol 14 (1-2) ◽  
pp. 54-58
Author(s):  
F.S. Glumcher ◽  
S.O. Solyaryk ◽  
O.V. Oliynyk ◽  
A.I. Kolosovych
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Visual Analog Scale ◽  
Surgical Intervention ◽  
Intraperitoneal Administration ◽  
Control Group ◽  
Average Dose ◽  
Analog Scale ◽  
Pain Evaluation ◽  
The Mean ◽  
Group 1

Relevance. The local anesthetics were used intraperitoneally after some minimally invasive gynecological interventions like a component of postoperative multimodal anesthesia in recent years.   Objective. The aim of  work was to study the effectiveness of intraperitoneal administration  of bupivokain  for the anesthesia of patients after laparoscopic cholecystectomy. Material and methods. 28 patients aged 32-60 years  (16 women, 12 men) were examined. The patients were divided into two groups. In the first group for anesthesia after the operation, was used ketorolac trometamine in dose 0.2 mg/kg intramuscularly each 6 hours. If the patient complained of postoperative pain, which was assessed by Visual-analog scale in 7 points or higher, fentanyl was administered intramuscularly in dose of 0.003 μg/kg. In the second group, besides the components of multimodal anesthesia used in the first group, at the end of the surgical intervention at the drainage tubes were injected 40 ml of 0.125% solution of bupivocaine (50 mg). This injection was repeated throughout the first day each 6 hours. The condition of patients was assessed by a Visual-analog scale after 1, 4, 8, 12 and 24 hours after the finishing of surgery. The average dose of fentanyl in μg/kg used for postoperative anesthesia  first 24 hours after operation was also determined. Results.  We have received a significant reduction in the rates of pain evaluation for Visual-analog scale in patients who used bupivacaine as a component of multimodal anesthesia. One hour after the end of the operation, the pain score for Visual-analog scale was less than the corresponding one in the control group in 1.77 times, after 4 hours – in 1.47, and in 8 hours – in 1.55 times. In all cases, P <0.001. The mean dose of fentanyl used for treatment in the study group was 1.55 times less than that in the control group. There were no significant complications in both groups. A patient in group 1 had nausea, requiring a single dose of ondasetron 2 mg Conclusion. Intraperitoneal administration of bupivocaine had a significant  anesthetic effect after laparoscopic cholecystectomy.

scholarly journals INTRAPERITONEAL USING OF BUPIVАCAIN FOR THE ANESTHESIA OF PATIENTS AFTER LAPAROSCOPIC CHOLECYSTECTOMY

2018 ◽  
Vol 14 (1-2) ◽  
pp. 54-58
Author(s):  
F.S. Glumcher ◽  
S.O. Solyaryk ◽  
O.V. Oliynyk ◽  
A.I. Kolosovych
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Visual Analog Scale ◽  
Surgical Intervention ◽  
Intraperitoneal Administration ◽  
Control Group ◽  
Average Dose ◽  
Analog Scale ◽  
Pain Evaluation ◽  
The Mean ◽  
Group 1

Relevance. The local anesthetics were used intraperitoneally after some minimally invasive gynecological interventions like a component of postoperative multimodal anesthesia in recent years.   Objective. The aim of  work was to study the effectiveness of intraperitoneal administration  of bupivokain  for the anesthesia of patients after laparoscopic cholecystectomy. Material and methods. 28 patients aged 32-60 years  (16 women, 12 men) were examined. The patients were divided into two groups. In the first group for anesthesia after the operation, was used ketorolac trometamine in dose 0.2 mg/kg intramuscularly each 6 hours. If the patient complained of postoperative pain, which was assessed by Visual-analog scale in 7 points or higher, fentanyl was administered intramuscularly in dose of 0.003 μg/kg. In the second group, besides the components of multimodal anesthesia used in the first group, at the end of the surgical intervention at the drainage tubes were injected 40 ml of 0.125% solution of bupivocaine (50 mg). This injection was repeated throughout the first day each 6 hours. The condition of patients was assessed by a Visual-analog scale after 1, 4, 8, 12 and 24 hours after the finishing of surgery. The average dose of fentanyl in μg/kg used for postoperative anesthesia  first 24 hours after operation was also determined. Results.  We have received a significant reduction in the rates of pain evaluation for Visual-analog scale in patients who used bupivacaine as a component of multimodal anesthesia. One hour after the end of the operation, the pain score for Visual-analog scale was less than the corresponding one in the control group in 1.77 times, after 4 hours – in 1.47, and in 8 hours – in 1.55 times. In all cases, P <0.001. The mean dose of fentanyl used for treatment in the study group was 1.55 times less than that in the control group. There were no significant complications in both groups. A patient in group 1 had nausea, requiring a single dose of ondasetron 2 mg Conclusion. Intraperitoneal administration of bupivocaine had a significant  anesthetic effect after laparoscopic cholecystectomy.

Study of Three Different Doses of Epidural Neostigmine Coadministered with Lidocaine for Postoperative Analgesia

1999 ◽  
Vol 90 (6) ◽  
pp. 1534-1538. ◽  
Author(s):  
Gabriela R. Lauretti ◽  
Raquel de Oliveira ◽  
Marlene P. Reis ◽  
Maria-do-Carmo C. Juliao ◽  
Newton L. Pereira
Keyword(s):  
Adverse Effects ◽  
Scale Score ◽  
Visual Analog Scale ◽  
Visual Analog Scale Score ◽  
Orthopedic Procedures ◽  
Control Group ◽  
Analog Scale ◽  
Analgesic Consumption ◽  
Group 2 ◽  
Group 1

Background Intrathecal neostigmine produces analgesia in volunteers and patients. However, the use of epidural neostigmine has not been investigated. The purpose of the current study was to define the analgesic effectiveness of epidural neostigmine coadministered with lidocaine and side effects in patients after minor orthopedic procedures. Methods After Institutional Review Board approval and informed consent, 48 patients (n = 12) undergoing knee surgery were randomly allocated to one of four groups and studied in a prospective way. After 0.05-0.1 mg/kg intravenous midazolam premedication, patients were randomized to receive 20 mg intrathecal bupivacaine plus epidural lidocaine (85 mg) with saline (control group); 1 microg/kg epidural neostigmine (1 microg group); 2 microg/kg epidural neostigmine (2 microg group); or 4 microg/kg epidural neostigmine (4 microg group). The concept of the visual analog scale, which consisted of a 10-cm line with 0 equaling "no pain at all" and 10 equaling "the worst possible pain" was introduced. Postoperatively, pain was assessed using the visual analog scale, and intramuscular 75 mg diclofenac was available at patient request. Results Groups were demographically the same and did not differ in intraoperative characteristics (blood pressure, heart rate, ephedrine consumption, oxyhemoglobin saturation, sensory loss before start of surgery, or duration of sensory motor block). The visual analog scale score at first rescue analgesic and the incidence of adverse effects were similar among groups (P &gt; 0.05). The time (min +/- SD) to first rescue analgesic was as follows: control group: 205+/-48; 1-microg group: 529+/-314; 2-microg group: 504+/-284; 4-microg group: 547+/-263 (P &lt; 0.05). The analgesic consumption (number of intramuscular diclofenac injections [mean, 25th-75th percentile]) in 24 h was as follows: control group: 3 [3 or 4]; 1-microg group: 1 [1 or 2]; 2-microg group: 2 [1 or 2]; 4-microg group: 2 [1-3] (P &lt; 0.05). The 24-h-pain visual analog scale score (cm +/- SD) that represents the overall impression for the last 24 h was as follows: control group: 5+/-1.6; 1-microg group: 1.6+/-1.8; 2-microg group: 1.4+/-1.6; 4-microg group: 2.2+/-1.9 (P &lt; 0.005). The incidence of adverse effects was similar among groups (P &gt; 0.05). Conclusion Epidural neostigmine (1, 2, or 4 microg/kg) in lidocaine produced a dose-independent analgesic effect (approximately 8 h) compared to the control group (approximately 3.5 h), and a reduction in postoperative rescue analgesic consumption without increasing the incidence of adverse effects.

Efficacy of Curcuminoids in managing postoperative pain after total laparoscopic hysterectomy: A randomized controlled, open-label trial.

2022 ◽  
Author(s):  
Chai Ariyasriwatana ◽  
Natacha Phoolcharoen ◽  
Shina Oranratanaphan ◽  
Pongkasem Worasethsin
Keyword(s):  
Postoperative Pain ◽  
Visual Analog Scale ◽  
Curcuma Longa ◽  
Laparoscopic Hysterectomy ◽  
Control Group ◽  
Analog Scale ◽  
Open Label ◽  
Vas Scores ◽  
The Mean ◽  
Experimental Group

Background and aims: Curcuminoids, which are substances extracted from turmeric (Curcuma longa), have anti-inflammatory and analgesic effects and a good safety profile. This study aimed to evaluate the clinical efficacy of curcuminoid extracts on reducing pain among patients who underwent laparoscopic hysterectomy. Experimental procedure: From November 2016 to December 2017, 98 participants were included in this clinical trial, and they were randomly assigned to the experimental and control arms according to blocks of four. The intraoperative findings did not significantly differ between the two groups. The experimental group received one tablet of curcuminoid extract 250 mg four times a day on postoperative days 1–3. Pain was evaluated at 24 and 72 h postoperatively using a 10-point visual analog scale (VAS). Results and conclusion: The mean visual analog scale (VAS) scores at 24 h after surgery were 4.9 in the experimental group and 4.3 in the control group. Hence, the results did not significantly differ (p = 0.129). The mean VAS scores at 72 h after surgery were 1.8 in the experimental group and 2.8 in the control group (p = 0.001). The side effects in both groups were similar. Hence, curcuminoids can be an effective supplement for reducing pain after laparoscopic hysterectomy. The conclusion from this study is, that curcuminoids may be an effective supplement to reduce postoperative pain following laparoscopic hysterectomy.

The effect of acupuncture on pain score after open kidney surgery

2015 ◽  
Vol 12 (3) ◽  
Author(s):  
Kamiar Tavakkoli Tabassi ◽  
Parisa Amini ◽  
Shabnam Mohammadi ◽  
Rahim Taghavi Razavizadeh ◽  
Amir Golchian
Keyword(s):  
Clinical Trial ◽  
Pain Score ◽  
Visual Analog Scale ◽  
Acupuncture Group ◽  
Control Group ◽  
Analog Scale ◽  
Gender And Age ◽  
The Mean ◽  
Spss Software ◽  
Scale Data

Abstract: The pain after nephrectomy, just as any other surgery, is one of the problems that surgeons confront. The aim of this study was to evaluate the relieving effect of acupuncture on the pain experienced after nephrectomy.: This was a clinical trial that was performed on 30 patients with mean age of 40.8 ± 12.54 who were candidates for nephrectomy. After matching for gender and age, the patients were divided into either acupuncture or control group. In acupuncture group, four points were stimulated for 30 minutes, and in control group, other points were stimulated ineffectively for 30 min. Then, the pain experienced in the first six hours after the surgery was registered by a blind observer based on visual analog scale. Data were analyzed using SPSS software and the t-test.: Our results showed that the severity of pain in the acupuncture group was significantly lower than that in the control group. Also, there were six patients who required opioids in the acupuncture group, but there were 12 such patients in the control group. The mean opiate used in the control group was significantly greater than the mean for the acupuncture group.: Acupuncture can reduce the severity of pain and the demand for opioids in patients who have undergone nephrectomy.

TO ASSESS THE IDEAL TIME OF LAPAROSCOPIC CHOLECYSTECTOMY AFTER ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY IN CASES OF CHOLELITHIASIS WITH CHOLEDOCHOLITHIASIS

2021 ◽  
Vol 5 (4) ◽  
Author(s):  
Dhirendra Godara ◽  
Vineet Choudhary ◽  
Nitish Soni
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Endoscopic Retrograde Cholangiopancreatography ◽  
Medical Sciences ◽  
Early Recovery ◽  
Endoscopic Retrograde ◽  
The Mean ◽  
Group 2 ◽  
Late Group ◽  
Group 1 ◽  
The Ideal

Background: Aims of this study was assess the ideal time of laparoscopic cholecystectomy after endoscopic retrograde cholangiopancreatography in cases of cholelithiasis with Choledocholthiasis Methods: The present study was carried out on 150 patients admitted in Department of General surgery National Institute of Medical Sciences and Research, Jaipur, diagnosed with cholelithiasis along with choledocholithiasis  from 1stJanuary 2019 to 30thJune, 2020. Results: In group 1 out of 75 patients 7 patients developed complications in post operative period compared to 35 patients out of 75 patients developed complications in group 2. The The mean hospital stay (in day) in group 1 patients was 2.26, median 2 and the mean of group 2 was 5.26, median 5. Conclusion: To conclude in our study there has been found significant advantage of early laparoscopic cholecystecomy following ERCP over the late group to minimize complications and promote early recovery of the patients. Keywords: ERCP, Cholecystectomy, Endoscopic retrograde cholangiopancreatography

scholarly journals The effect of local ketamine infiltration on post tonsillectomy pain scale

2020 ◽  
Vol 50 (1) ◽  
pp. 38
Author(s):  
Ade Asyari ◽  
Novialdi Novialdi ◽  
Elniza Morina ◽  
Rimelda Aquinas ◽  
Nasman Puar ◽  
...  
Keyword(s):  
Visual Analog Scale ◽  
Secondary Infection ◽  
Pain Scale ◽  
Control Group ◽  
Analog Scale ◽  
Noticeable Effect ◽  
Local Infiltration ◽  
Significant Difference ◽  
Post Test ◽  
Test Control

Background: Post tonsillectomy pain is one of the surgery side effects that most disturbing for patient’s comfort and will cause dysphagia, low intake, dehydration, secondary infection and bleeding. Ketamine is an anesthetic drug that has strong analgesic effect and easily available in any hospital at relatively cheap price. Objective: To find out the effect of local ketamine infiltration on the post tonsillectomy pain scale. Method: An experimental study during tonsillectomy with a Post Test Control Group on 12 samples without local infiltration of ketamine and 12 samples with local infiltration of ketamine in peritonsillar pillar. The pain was assessed 2 hours and 24 hours post extubation with pain Visual Analog Scale (VAS). Result: The VAS value from patients who were given local infiltration of ketamine in peritonsillar pillar were lower (5.83 ± 0.72 at 2 hours and 2.83 ± 0.58 at 24 hours post extubation) compared to patients without ketamine infiltration (7.83 ± 0.58 at 2 hours and 3.58 ± 0.51 at 24 hours post extubation). The result showed statistically significant difference (p <0.05) at 2 hours and 24 hours post extubation. Conclusion: The VAS score of the ketamine infiltration group is lower at 2 hours and 24 hours post extubation than the group without ketamine infiltration, showing there was a noticeable effect of local ketamine infiltration on the post tonsillectomy pain scale.Keywords : post tonsillectomy pain, ketamine, local infiltration, visual analog scale ABSTRAKLatar belakang: Nyeri pascatonsilektomi adalah salah satu efek samping operasi yang sangat mengganggu kenyamanan pasien, dan dapat menyebabkan gangguan menelan, kurangnya asupan nutrisi, dehidrasi, infeksi sekunder dan perdarahan. Ketamin merupakan obat anestesi yang memiliki efek analgetik yang kuat dan mudah didapatkan di semua tipe rumah sakit dengan harga yang relatif murah. Tujuan: Mengetahui efek pemberian infiltrasi lokal ketamin terhadap skala nyeri pascatonsilektomi. Metode: Penelitian eksperimental dengan desain Post Test Control Group pada 12 sampel tanpa pemberian infiltrasi lokal ketamin dan 12 sampel dengan pemberian infiltrasi lokal ketamin di pilar peritonsil saat tonsilektomi. Dilakukan penilaian nyeri 2 jam dan 24 jam pascaekstubasi menggunakan skala nyeri Visual Analog Scale (VAS). Hasil: Nilai VAS pasien yang diberi infiltrasi lokal ketamin di pilar peritonsil lebih rendah (5,83±0,72 pada 2 jam dan 2,83 ± 0,58 pada 24 jam pascaekstubasi) dibanding tanpa diberi infiltrasi lokal ketamine (7,83 ± 0,58 pada 2 jam dan 3,58± 0,51 pada 24 jam pascaekstubasi), dan bermakna secara statistik (p<0,05) pada kedua penilaian. Kesimpulan: Terdapat efek nyata infiltrasi lokal ketamin terhadap skala nyeri pascatonsilektomi, dimana nilai VAS kelompok yang diberi infiltrasi ketamin lebih rendah, baik pada 2 jam ataupun 24 jam pascaekstubasi dibanding kelompok yang tidak diberi infiltrasi ketamin.

scholarly journals Spinal cord stimulation for chronic intractable trunk or limb pain: study protocol for a Chinese multicenter randomized withdrawal trial (CITRIP study)

2020 ◽  
Author(s):  
Yang Lu ◽  
Peng Mao ◽  
Guihuai Wang ◽  
Wei Tao ◽  
Donglin Xiong ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Visual Analog Scale ◽  
Spinal Cord Stimulation ◽  
Pulse Generator ◽  
Short Form ◽  
Control Group ◽  
Withdrawal Period ◽  
Analog Scale ◽  
Limb Pain ◽  
Vas Score

Abstract Background: Although effective results of many studies support the use of spinal cord stimulation in the chronic pain patients, no randomized controlled trial has been undertaken in China to date. CITRIP is a multicenter, prospective, randomized, withdrawal study designed to evaluate the clinical effectiveness and safety of spinal cord stimulation plus remote programming management in patients with intractable trunk or limb pain.Method：Participants will be recruited in approximately 10 centers across China. Eligible participants with intractable trunk or limb and an average Visual Analog Scale (VAS) score ≥ 5 will undergo spinal cord stimulation test. Participants with VAS score reduction ≥ 50% could move forward to receive implantation of an implanted pulse generator. In the withdrawal period at 3-months follow-up visit, participants randomized to the experimental group (EG) will undergo continuous stimulation while ceasing the stimulation in the control group (CG). The outcome assessment will occur at baseline and at 1, 3 (pre and post randomization) and 6 months. The primary outcome is the difference of maximal visual analog scale (VAS) score between EG and CG in the withdrawal period compared with baseline before the withdrawal period. Additional outcomes include VAS score change at 1, 3 and 6-month follow-ups, responder rate (VAS score improving by 50%), achievement rate of a desirable pain state (VAS score ≤ 4), awake times during sleep, Beck Depression Inventory for depression evaluation, short-form 36 for quality of life evaluation, drug usage, satisfaction rating of the device. Adverse events will be collected. The primary analysis will follow the intention-to-treat principle. Discussion：The CITRIP study seeks to evaluate the effectiveness and safety of a randomized withdrawal trial of spinal cord stimulation for patients with intractable trunk or limb pain.Trial registration: NCT03858790, clinicaltrials.gov, registered on March 1st, 2019, retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT03858790

scholarly journals PENGARUH INTRADYALITIC EXERCISE TERHADAP PENURUNAN NYERI PASIEN HEMODIALISA RUTIN DI UNIT HEMODIALISA RSUD Dr. TJITROWARDOJO PURWOREJO

2018 ◽  
Vol 3 (1) ◽  
Author(s):  
Wiwit Sugiarti ◽  
Sri Nabawiyati Nurul Makiyah ◽  
Azizah Khoiriyati
Keyword(s):  
Visual Analog Scale ◽  
Control Group ◽  
P Value ◽  
Analog Scale ◽  
Intradialytic Exercise

Latar belakang; Nyeri muskuloskeletal merupakan gejala yang dialami pasien gagal ginjal kronik yang menjalani hemodialisa.Manajemen nyeri dapat menggunakan distraksi relaksasi konvensional dan intradialytic exercise. Penelitian ini bertujuan untuk mengetahui efektivitas Intradialytic exercise dalam menurunkan nyeri pada pasien hemodialisa rutin di Unit Hemodialisa Rumah Sakit Umum Daerah Dr. Tjitrowardojo Purworejo.Metode; Rancangan penelitian yang digunakan eksperimen semu dengan desain pretest-posttest with control group. Respondennya 36 orang, terdiri dari 18 pasien yang diberi Intradialytic exercise sebagai kelompok intervensi dan 18 pasien lainnya hanya diberikan distraksi-relaksasi konvensional sebagai kelompok kontrol.  Pengukuran nyeri menggunakan Visual Analog Scale. Analisis datanya menggunakanPaired t Testdan  Independent Sample t Test.Hasil;  Hasil penelitian didapatkan perbedaan penurunan yang signifikan terhadap skor nyeri pre dan postes pada kelompok baik intervensi dan kelompok kontrol dengan p value 0,000 (p< 0,005 dan metode Intradialytic exercise lebih efektif dalam menurunkan skor nyeri dibandingkan metode distraksi-relaksasi konvensional pada pasien HD rutin  dengan p value 0,000 (p< 0,005). Kata kunci: Intradialytic Exercise, Nyeri

Effect of Chlorophyllin on Urinary Odor in Incontinent Geriatric Patients

1983 ◽  
Vol 17 (10) ◽  
pp. 732-734 ◽  
Author(s):  
Milap C. Nahata ◽  
Carole A. Slencsak ◽  
Judith Kamp
Keyword(s):  
Visual Analog Scale ◽  
Washout Period ◽  
Geriatric Patients ◽  
Odor Intensity ◽  
Controlled Study ◽  
Analog Scale ◽  
Double Blind ◽  
Mean Intensity ◽  
The Mean ◽  
Percent Decrease

This randomized, double-blind, crossover, placebo-controlled study involved 20 incontinent geriatric patients; all had indwelling Foley catheters. Each patient received chlorophyllin 100 mg/d for two weeks and placebo daily for two weeks, separated by a washout period of one week. For each subject, the intensity of urinary odor was measured ten times during both the treatment and placebo regimen and three times during the washout period, using a visual analog scale. A decrease in urinary odor was associated with chlorophyllin in 12 patients and with placebo in 6 patients at the end of two weeks on each regimen. Chlorophyllin treatment was associated with about a 21-percent decrease in mean urinary odor intensity, whereas placebo increased the odor by about 9 percent. The mean intensity of urinary odor was lowest during the second week of chlorophyllin treatment. Despite the decrease in urinary odor in many patients receiving chlorophyllin, its effect was not significantly greater than that of placebo. Our data suggest that chlorophyllin 100 mg/d for two weeks may not be effective in incontinent geriatric patients with mild to moderate urinary odor.

Psychiatric Morbidity in Sentenced Segregated HIV-Positive Prisoners

1993 ◽  
Vol 163 (6) ◽  
pp. 802-805 ◽  
Author(s):  
Arthur Dorman ◽  
Art O'Connor ◽  
Eamonn Hardiman ◽  
Aideen Freyne ◽  
Helen O'Neill
Keyword(s):  
Drug Abuse ◽  
Matched Control ◽  
Psychiatric Morbidity ◽  
Hiv Positive ◽  
Control Group ◽  
Matched Control Group ◽  
History Of ◽  
The Mean ◽  
Group 2 ◽  
Group 1

In this comparative study with a control group of prisoners, psychiatric morbidity was measured in two groups of sentenced prisoners, each group completing the GHQ-30 and 21-item Beck Depression Inventory (BDI). Group 1 consisted of 40 segregated HIV-positive prisoners and group 2 a matched control group in the main prison who had no history of HIV seropositivity. All members of group 1 had a history of intravenous drug abuse. The mean GHQ-30 and BDI scores were significantly higher in group 1, and 90% of group 1 were psychiatric ‘cases’ compared with just over 42% of group 2. Levels of psychiatric morbidity present in a third group, consisting of HIV-positive prisoners who had not been segregated (prison authorities were unaware of their seropositivity) are an interesting pointer for further research.

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