scholarly journals Postinfectious irritable bowel syndrome in children

2021 ◽  
Vol 4 (3) ◽  
pp. 292-297
Author(s):  
D.V. Pechkurov ◽  
◽  
A.A. Tyazheva ◽  

Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders in adults, children, and adolescents. This paper reviews the etiology and pathogenesis of IBS, particularly one of its subtypes, postinfectious IBS, associated with a prior acute intestinal infection. The authors discuss risk factors, diagnosis, and treatment for postinfectious IBS and describe diagnostic search and therapeutic algorithm in a child. Treatment for IBS involves changes in diet and lifestyle, pharmacotherapy, and psychotherapy. This case report is interesting for clinicians since only attempts are made to systematize guidelines on the diagnosis and treatment for postinfectious IBS. However, specific management strategies for this condition are scarce, making the diagnosis difficult and resulting in treatment delay. KEYWORDS: irritable bowel syndrome, functional gastrointestinal disorders, prokinetic agent, synbiotic, Maxilac. FOR CITATION: Pechkurov D.V., Tyazheva A.A. Postinfectious irritable bowel syndrome in children. Russian Journal of Woman and Child Health. 2021;4(3):292–297 (in Russ.). DOI: 10.32364/2618-8430-2021-4-3-292-297.

Author(s):  
A.V. Zubarenko ◽  
V.V. Luzan ◽  
T.Yu. Kravchenko ◽  
G.K. Kopiyka ◽  
V.I. Martyuk

Functional gastrointestinal disorders are considered as a clinical variant of the interaction between psychosocial factors and gastrointestinal tract physiology implemented through the "brain - intestine" axis. The purpose of the study was to investigate psychological peculiarities of children with irritable bowel syndrome. The study included 68 children aged from 14 to 18 years with the confirmed diagnosis of irritable bowel syndrome. To determine the type of character accentuation, the Schmishek -Leonhard test questionnaire (child version) was used. The SCL-90-R test questionnaire (by L. Derogatis method) was applied to determine psycho-emotional disorders. The study has found out the majority of patients have certain psycho-emotional disorders. The group of children with irritable bowel syndrome, who were experiencing constipation, more frequently demonstrated an emotional type of character accentuation and a somatized and depressed type of psychological disorders. The patients with irritable bowel syndrome and diarrhoea had cycloid and demonstrative types of character accentuation and demonstrated an anxious type according to the questionnaire. The patients with mixed bowel rhythms exhibited features of a cycloid, emotional, and pedantic type of character accentuation. Depression, anxiety, somatised types were reported as manifestations of psychological disorders.


2020 ◽  
Vol 11 ◽  
Author(s):  
Chloé Melchior ◽  
Charlotte Desprez ◽  
Fabien Wuestenberghs ◽  
Anne-Marie Leroi ◽  
Antoine Lemaire ◽  
...  

Objective: We aimed to determine the burden of opioid consumption in a cohort of patients with functional gastrointestinal disorders.Methods: All patients diagnosed with functional gastrointestinal disorders and referred to our university hospital were evaluated from 2013 to the beginning of 2019. Irritable bowel syndrome and functional dyspepsia diagnoses were determined according to Rome criteria and severity according to irritable bowel syndrome severity scoring system. Vomiting was quantified using a 5-point Likert scale, and constipation severity was measured using the Knowles-Eccersley-Scott-Symptom questionnaires. Quality of life was quantified by the GastroIntestinal Quality of Life Index. Patients were categorized as being treated on a chronic basis with either tramadol, step II opioids, step III opioids or as being opioid-free.Results: 2933 consecutive patients were included. In our cohort, 12.5% had only irritable bowel syndrome, 39.3% had only functional dyspepsia, 24.9% had a combination of both, and 23.4% had other functional gastrointestinal disorders. Among them, the consumption of tramadol, step II (tramadol excluded) and step III opioids was 1.8, 1.3 and 0.3 % respectively in 2013 and 4.3, 3.4 and 1.9% in 2018 (p < 0.03). Opioid consumption was associated with increased vomiting (p = 0.0168), constipation (p < 0.0001), symptom severity (p < 0.001), more altered quality of life (p < 0.0001) and higher depression score (p = 0.0045).Conclusion: In functional gastrointestinal disorders, opioid consumption has increased in the last years and is associated with more GI symptoms (vomiting, constipation and GI severity), higher depression and more altered quality of life.


2015 ◽  
Vol 6 (2) ◽  
pp. 209-217 ◽  
Author(s):  
S. Guandalini ◽  
E. Cernat ◽  
D. Moscoso

Underlying pathophysiological mechanisms of irritable bowel syndrome (IBS), a common disorder characterized by abdominal pain associated to a change in stool consistency or frequency, include low-grade inflammation and intestinal microbiota changes. Few and disappointing data are available for prebiotics. A few controlled trials (RCTs) of probiotics are instead available with favourable effects, although most are limited by suboptimal design and small sample size. A recent report from the Rome foundation group included 32 RCTs of probiotics, most of which showed an overall modest improvement in symptoms, with the patients most benefitting from probiotics being those with predominant diarrhoea and those having a post-infectious IBS. A review focusing only on children with functional gastrointestinal disorders concluded that probiotics are more effective than placebo in the treatment of patients with abdominal pain-related functional gastrointestinal disorders, although no effect on constipation was evident. The role for probiotics in inflammatory bowel disease (IBD) appears logical: the endogenous intestinal microbiota plays a central role in their development, and various probiotics have been found effective in animal models of IBD. However, research in humans has been overall quite limited, and it would seem that after a phase of intense research in the first decade of this century, the pace has slowed down, with fewer clinical trials been published in the past 2-3 years. To summarize current evidence: no probiotic has proven successful in Crohn's disease. In ulcerative colitis, on the other hand, data are more promising, and a very recent meta-analysis, that included 23 randomized controlled trials, concluded that there is evidence of efficacy for the probiotic mixture VSL#3 in helping inducing and maintaining remission, as well as in maintaining remission in patients with pouchitis. It is fair to state that for both IBD and IBS, more well-designed, rigorous, randomized clinical trials must be performed.


2022 ◽  
Vol 49 (3) ◽  
pp. 1-6
Author(s):  
Türkan Kutluay Merdol

Fonksiyonel gastrointestinal bozukluklar (FGID-functional gastrointestinal disorders) herhangi bir organik bozukluk olmamasına karşın kronik veya tekrarlayan gastrointestinal semptomlara verilen genel bir addır. Bu bozukluklarda diyetin, hastaya özel olarak hazırlanması ve sürekli izlenmesi çok büyük önem taşımaktadır. Bu süreçte, hastanın beslenme alışkanlıklarının deneyimli diyetisyenler tarafından belirlenmesi ve hasta ile karşılıklı olarak tüm biyo-psiko-sosyal yönler dikkate alınarak incelenmesi, buna göre kişiye özel beslenme ve diyet planının tanzim edilmesi gerekmektedir. FGID’ler arasında en yaygın semptomlar bütünü IBS (Irritable Bowel Syndrome-huzursuz bağırsak sendromu) olarak adlandırılan bozukluktur. IBS’lerde diyetisyenin rolü diğer FGID’lere göre daha da önemli ve özeldir. Türkiye’de diyetisyenlerin bu bozukluklar alanında uzmanlaşması için gerekli adımlar ivedilikle atılmalı ve sağlık kurumlarında diyetisyen kadrosu istihdamı da arttırılmalıdır.


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